Mohammad Yazdi, Amirhossein Nafari, Mojgan Azadpour, Mahdi Alaee, Forouzan Hadipour Moradi, Razieh Choghakhori, Maryam Hormozi, Hassan Ahmadvand
BACKGROUND: Cinnamic acid, a phenylpropanoid acid, has been investigated as a potential alternative therapy for diabetes and its complications in some studies. METHODS: In the first stage, the viability of HepG2 cells at different concentrations of glucose and CA was assessed by MTT assay. Oxidative stress markers) CAT, GPx, GSH, and MDA) were measured spectrophotometrically. After RNA extraction, the effect of different concentrations of CA on the expression of DPP4 and inflammatory factors (IL-6, NF- κB) in HepG2 cells was assessed using real-time PCR...
April 2023: Reports of Biochemistry & Molecular Biology