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Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)

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https://read.qxmd.com/read/30864371/hyperfibrinogenemia-in-peripheral-arterial-disease-coexistent-and-independent-risk-factor-a-report-of-two-cases-and-review-of-literature
#1
Marijan Bosevski, Gorjan Krstevski, Irena Mitevska, Emilija Antova, Golubinka Bosevska
These case reports aim to show that hyperfibrinogenemia is a risk factor for the progression and prognosis of peripheral arterial disease (PAD), in patients with and without diabetes mellitus type 2. We present a patient with PAD who has type 2 diabetes mellitus, who has previously been repeatedly treated for lower limb ischemia with multiple vascular surgeries performed. A few weeks before admission the patient developed critical lower limb ischemia, which was treated with an iliaco-popliteal and femorofemoral bypass...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864370/comparison-of-argon-plasma-coagulation-and-injection-therapy-with-adrenalin-and-polidocanol-in-the-management-of-bleeding-angiodysplasia-in-upper-gastrointestinal-tract
#2
Atip Ramadani, Rozalinda Popova Jovanovska, Meri Trajkovska, Vladimir Andreevski, Viktorija Calovska, Vladimir Serafimoski, Sonja Bojadzieva
INTRODUCTION: The term angiodysplasia (AD) refers to acquired malformation of the blood vessels (communications between veins and capillaries), frequently found within the gastrointestinal mucosa and submucosa. AD of stomach and duodenum are cause of upper gastrointestinal bleeding in 4%-7% of patients. The means of treatment are usually endoscopic, including argon plasma coagulation (APC), electrocoagulation, mechanical hemostasis by clippsing, laser photo-coagulation and injection therapy...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864369/a-4-year-old-boy-with-beckwith-wiedemann-syndrome-bws
#3
Aleksandra Janchevska, Velibor Tasic, Nevenka Laban, Momir Polenakovic, Zoran Gucev, Nadine Bachmann, Carsten Bergmann
OBJECTIVES: Molecular characterization of a patient with BWS. CLINICAL PRESENTATION AND INTERVENTION: A 4-year-old boy with overgrowth (weight above 99th and height at 99th percentile) had longitudinal hemihypertrophy of the tongue and left cheek. In addition, there was a difference of one centimeter in the circumference of the left and right leg. Molecular genetic analysis revealed hypomethylation of KvDRM1 (LIT1) in the imprinting control region-2 (ICR2) on chromosome 11p15...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864368/immunohistochemical-expression-of-epidermal-growth-factor-receptor-in-hepatocellular-carcinoma
#4
Dafina Nikolova, Viktorija Chalovska, Magdalena Genadieva Ivanova, Emilija Nikolovska, Ance Volkanovska, Nikola Orovchanec, Slavica Kostadinova Kunovska, Gordana Petrushevska, Vesna Janevska
INTRODUCTION: Epidermal growth factor receptor (EGFR) signaling plays an important role in various cancers, including hepatocellular carcinoma (HCC). We aimed to evaluate immunoexpression of EGFR in HCC and surrounding non-tumor liver tissue and to correlate it to multiple clinicopathologic data. MATERIAL AND METHODS: We analyzed 60 patients with HCC for multiple clinicopathologic characteristics and survival. Presence of the immunosignal and the percentage of positive tumor cells at the whole tumor tissue sample and adjacent cirrhotic liver tissue were semi-quantitatively determined...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864367/nutritional-assessment-of-dialysis-patient-with-a-web-based-tool-allows-more-accurate-treatment-of-malnutrition
#5
Mihela Ferlinc, Bojan Knap
BACKGROUND/AIMS: Regular assessment of nutritional status of dialysis patients is vital for preventing malnutrition and protein energy wasting. The aim of this clinical study was to analyze dietary intake of dialysis patients and to determine if it meets their nutritional needs. METHODS: Clinical study was conducted on 30 randomly selected dialysis patients in the dialysis department of the University Medical Centre Ljubljana. Nutritional interview was conducted unannounced five times over a period of three months with the 24-hour recall method...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864366/evaluation-of-correlation-between-the-pharmacogenetic-profiles-of-risperidone-treated-psychiatry-patients-with-plasma-and-urine-concentration-of-risperidone-and-its-active-moiety-9-oh-risperidone-determined-with-optimized-bioanalytical-lc-method
#6
Ana Filipce, Zorica Naumovska, Aleksandra Kapedanovska Nestorovska, Zoran Sterjev, Katerina Brezovska, Jasmina Tonic-Ribarska, Aleksandra Grozdanova, Ljubica Suturkova, Marija Raleva
Atypical antipsychotic risperidone is widely used first-line monotherapy in schizophrenia and combined therapy in bipolar disorders. Therapeutic plasma concentrations of risperidone and its active moiety are directly influenced by genetic variations in metabolic CYP450 enzymes (CYP2D6 and CYP3A4/5) and transporter (ABCB1) protein and additional environmental factors. Since active metabolite 9-OH risperidone has a greater percentage of the pharmacologically active fraction and is equipotent to the parent drug risperidone, it is assumed that it contributes significantly to therapeutic and adverse effects...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864365/epidemiological-analysis-and-geographical-distribution-of-patients-suffering-from-rheumatoid-arthritis-eligible-for-first-line-therapy-monotherapy-treatment-with-subcutaneous-formulation-of-tocilizumab-in-the-republic-of-macedonia
#7
Filip Gucev, Snezana Perchinkova-Mishevska, Georgi Bozinovski, Irena Kafedjiska, Dubravka Antova, Ljubinka Damjanovska-Krstic, Bashkim Osmani, Fjola Hadjihamza, Oliver Nikolov
Rheumatoid arthritis is an inflammatory arthritis characterized by synovial tissue inflammation that leads to structural damage and disability. There are several treatment options available, which include glucocorticoids, DMARDs and biologics given alone as monotherapy or in a variety of combinations. Recent evidence has shown that early treatment is important in reducing the rate of progression of erosions and decreasing disability. The lack of adequate statistical data on number of patients that are eligible for first-line therapy/monotherapy of rheumatoid arthritis in Macedonia, triggered this epidemiological analyse describing eligible patients for first-line treatment/monotherapy distributed by gender, age and geographical allocation...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864364/icgeb-workshop-on-next-generation-diagnostics-22-03-2018-24-03-2018-macedonian-academy-of-sciences-and-arts-skopje-republic-of-macedonia
#8
Dimitar Efremov, Momir Polenakovic
More than 200 participants from Europe, Asia, Africa and South America attended the two days ICGEB Workshop on Next Generation Diagnostics, 22/03/2018-24/03/2018, at the Macedonian Academy of Sciences and Arts (MASA) in Skopje, Republic of Macedonia. The meeting provided an overview of the current and future use of next generation sequencing (NGS), proteomics and other high-throughput technologies in the diagnostic setup of malignant, inherited and communicable diseases. In addition, considerable emphasis was placed on the potential use of these techniques for disease prognostication, patient stratification and monitoring responses to therapy...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864363/the-effect-of-continuous-renal-replacement-therapy-with-the-an69st-membrane-on-inflammatory-markers-and-the-level-of-consciousness-of-hemodialysis-patients-with-stroke-comparison-with-hemodialysis-with-low-blood-flow-rate
#9
Tomohiro Matsui, Takafumi Nakagawa, Hitomi Kikuchi, Hiroyuki Horio, Kazuhiko Hashimura
INTRODUCTION: Hemodialysis (HD) with low blood flow rate, continuous renal replacement therapy (CRRT), and peritoneal dialysis are recommended for patients with stroke complications to prevent intracranial hypertension because of the low diffusion capacity of the brain barrier. However, detailed guidelines are not currently available; thus, there is an urgent need to establish such guidelines. MATERIAL AND METHODS: We developed a novel protocol for performing CRRT with the AN69ST membrane, which has excellent adsorption capacity for various cytokines...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864362/community-acquired-legionnaire-s-disease-in-a-kidney-transplant-patient
#10
Jason Kirincich, Zrinka Sakic, Armin Atic, Nikolina Basic-Jukic
This case report details the clinical picture of a renal transplant recipient infected with community acquired Legionella pneumonia. While it is more commonly associated as a nosocomial infection due to pathogenic organisms in a hospital's water supply, this case serves as a reminder to consider the patient's impaired cellular immune function when trying to diagnose community acquired pneumonia.
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864361/evaluation-of-pain-following-the-use-of-scalpel-versus-electrosurgery-for-skin-incisions-in-the-facial-regions
#11
Margarita Peneva, Andrijana Gjorgjeska, Smilja Tudzarova Gjorgova, Boro Dzonov, Lazo Noveski, Vladimir Ginoski, Roza Dzoleva Tolevska, Hristina Breshkovska
INTRODUCTION: Postoperative pain presents a significant medical problem. It can create a considerable discomfort in the immediate postoperative period and thus increase patient's morbidity. Multiple mechanisms are involved in its' etiology, one of them being the method of tissue incision. The aim of this study is to compare the early postoperative pain following incision with two different methods, scalpel and electrosurgery in the facial regions. MATERIAL AND METHODS: Eighty patients with both benign and malignant skin lesions in the facial regions undergoing surgery were enrolled in this study...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864360/opioid-free-anesthesia-for-laparotomic-hemicolectomy-a-case-report
#12
Marija Toleska, Biljana Kuzmanovska, Andrijan Kartalov, Mirjana Shosholcheva, Jasminka Nancheva, Aleksandar Dimitrovski, Natasha Toleska
Opioid free anesthesia (OFA) is deffined as anaesthesiological technique where opioids are not used in the intraoperative period (systemic, neuroaxial or intracavitary). Anaphylaxis caused by opioids (fentanyl) is very rare, and the reaction is presented with hypotension and urticaria. When we have proven allergy to fentanyl, patients' refusal of placing epidural catheter and refusal of receiving bilateral ultrasound guided transversus abdominis plane block (USG TAPB), we must think of using multimodal nonopioide analgesia...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864359/myocardial-perfusion-abnormalities-in-young-and-premenopausal-women-with-systemic-lupus-erythematosus-detected-with-99mtc-mibi-myocardial-perfusion-scintigraphy-prevalence-and-correlation-with-proatherogenic-factors
#13
Emilija Sandevska, Daniela Pop Gjorcheva, Marija Vavlukis, Aleksandar Sandevski, Irena Kafedziska, Ljubinka Krstik-Damjanovska, Venjamin Majstorov, Sasha Jovanovska-Perchinkova, Filip Guchev, Nela Kostova
INTRODUCTION: Atherosclerosis in young and premenopausal women with systemic lupus erythematosus (SLE) is frequent, premature and progressive. Although asymptomatic or with atypical clinical presentation, the patients are at high risk of cardiac events. Aim of this study is to estimate the risk profile for atherogenesis and the prevalence of myocardial perfusion abnormalities with 99mTc myocardial perfusion scintigraphy (MPS) in young and premenopausal women. MATERIAL AND METHODS: Sixty female patients, aged 30-72 years (divided into two subgroups - patients under 45 years of age and patients over 45 years), diagnosed with SLE for over of 5 years, in active phase of the disease were analyzed for disease activity scores (SLEDAI), the immunologic status of the disease (ANA and a-DNA antibodies in the serum), procoagulant tendency (antiphospholipid antibodies-APhL and lupus-anticoagulant-LAC), the activity of the inflammatory process (hsCRP), the anti-SLE therapeutic approach and the presence of traditional risk factors for atherosclerosis (BMI, smoking, hypertension, hyperlipidemia, diabetes, and familial history for the CAD)...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864358/jakub-chlebowski-rector-magnificus-exultus-a-distinguished-professor-of-internal-medicine-in-postwar-north-east-poland
#14
Andrzej Wincewicz, Piotr Woltanowski, Stanisław Sulkowski, Jolanta Małyszko
Jakub Chlebowski (Jakub Frydman) (1905-1969) was a distinguished professor of internal medicine and skillful organizer of health care system in Bialystok region in the North east Poland. He graduated medicine in 1929 and worked at local university in prewar Vilnius. During World War Two, arrested by the Soviets and exiled to Siberian work camps he managed to return to Poland with Kosciuszko Division of Polish Army. Then, he continued to serve as a military and university medical doctor in Cracow and Lodz, finally to take over position of director of Internal Diseases Department in 1951 in Bialystok, holding an office of rector magnificus of Medical University of Bialystok from 1959 to 1962...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864357/assessment-of-malnutrition-inflammation-score-in-different-stages-of-chronic-kidney-disease
#15
H K Aggarwal, Deepak Jain, Rahul Chauda, Shailesh Bhatia, Rajnish Sehgal
BACKGROUND: Protein-energy wasting (PEW) is common in patients with chronic kidney disease (CKD), and is associated with high morbidity and mortality. Malnutrition-Inflammation Score (MIS) has significant correlations with prospective hospitalization and mortality, as well as measures of anemia, inflammation, and nutrition in dialysis patients. MATERIAL AND METHODS: The study was conducted on 100 adult patients of CKD selected from K&D clinic PGIMS, Rohtak. All the patients went under detailed socioeconomic, clinical, biochemical and radiological examination...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864356/intrapartum-procedures-for-prevention-of-infections-and-complications-in-mothers-during-childbirth
#16
Svetlana Krstevska Blazhevska, Doncho Donev
INTRODUCTION: Multiple factors can cause infection and other pathological conditions in mothers during childbirth. These risk factors and diseases/complications can be prevented or timely detected through the implementation of special protocols/procedures. The aim of this paper is to identify the implementation of procedures/measures for the prevention and detection of infections and risk factors for morbidity and mortality in four hospitals in the Republic of Macedonia, before and during childbirth...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864355/giant-fibroepithelial-polyp-of-vulva-a-case-report-and-review-of-literature
#17
Meral Rexhepi, Elizabeta Trajkovska, Florin Besimi, Nagip Rufati
Fibroepithelial stromal polyps of vulva are the type of mesenchymal lesion that typically occurs in women of reproductive period. They are common, usually small and hystologically benign. Larger lesions are rare and likely arise from proliferation of mesenchymal cells within the hormonally sensitive subepithelial stromal layer of the lower genital tract. We present a case of 16 year old female with a giant polypoid lesion of the vulva localized on the right labium. The mass measure was 18×12×3 cm. Total surgical resection of the lesion was performed...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30864354/inter-and-intra-hemispheric-eeg-coherence-study-in-adults-with-neuropsychiatric-disorders
#18
Silvana Markovska-Simoska, Nada Pop-Jordanova, Jordan Pop-Jordanov
Functional connectivity between different regions of the brain in the resting state has been a recent topic of interest in neurophysiological research. EEG coherence happened to be an useful tool for measuring changes in neuro-psycho-physiological functioning which are not detectable by simply measuring amplitude or power spectra. The aim of our study was to investigate the changes in the EEG coherence in groups of different mental disorders such as: depression, general anxiety disorder, ADHD, Asperger syndrome and headaches, compared to control group...
December 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30110272/originally-adapted-mobile-application-used-for-neuropsychiatric-patients
#19
Nada Pop-Jordanova, Sofija Loleska, Mario Loleski
No abstract text is available yet for this article.
July 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/30110271/analysis-of-bone-metabolism-in-children-with-cystic-fibrosis
#20
Tatjana Jakovska
No abstract text is available yet for this article.
July 1, 2018: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
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