journal
https://read.qxmd.com/read/38750178/author-correction-peptidoglycan-synthesis-drives-a-single-population-of-septal-cell-wall-synthases-during-division-in-bacillus-subtilis
#1
Kevin D Whitley, James Grimshaw, David M Roberts, Eleni Karinou, Phillip J Stansfeld, Séamus Holden
No abstract text is available yet for this article.
May 15, 2024: Nature Microbiology
https://read.qxmd.com/read/38750177/the-meaning-of-oral-bacteria-in-faeces
#2
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
May 15, 2024: Nature Microbiology
https://read.qxmd.com/read/38750176/peptostreptococcus-anaerobius-mediates-anti-pd1-therapy-resistance-and-exacerbates-colorectal-cancer-via-myeloid-derived-suppressor-cells-in-mice
#3
JOURNAL ARTICLE
Yali Liu, Chi Chun Wong, Yanqiang Ding, Mengxue Gao, Jun Wen, Harry Cheuk-Hay Lau, Alvin Ho-Kwan Cheung, Dan Huang, He Huang, Jun Yu
Bacteria such as the oral microbiome member Peptostreptococcus anaerobius can exacerbate colorectal cancer (CRC) development. Little is known regarding whether these immunomodulatory bacteria also affect antitumour immune checkpoint blockade therapy. Here we show that administration of P. anaerobius abolished the efficacy of anti-PD1 therapy in mouse models of CRC. P. anaerobius both induced intratumoral myeloid-derived suppressor cells (MDSCs) and stimulated their immunosuppressive activities to impair effective T cell responses...
May 15, 2024: Nature Microbiology
https://read.qxmd.com/read/38740932/propionate-prevents-loss-of-the-pdim-virulence-lipid-in-mycobacterium-tuberculosis
#4
JOURNAL ARTICLE
Claire V Mulholland, Thomas J Wiggins, Jinhua Cui, Catherine Vilchèze, Saranathan Rajagopalan, Michael W Shultis, Esmeralda Z Reyes-Fernández, William R Jacobs, Michael Berney
Phthiocerol dimycocerosate (PDIM) is an essential virulence lipid of Mycobacterium tuberculosis. In vitro culturing rapidly selects for spontaneous PDIM-negative mutants that have attenuated virulence and increased cell wall permeability, thus impacting the relevance of experimental findings. PDIM loss can also reduce the efficacy of the BCG Pasteur vaccine. Here we show that vancomycin susceptibility can rapidly screen for M. tuberculosis PDIM production. We find that metabolic deficiency of methylmalonyl-CoA impedes the growth of PDIM-producing bacilli, selecting for PDIM-negative variants...
May 13, 2024: Nature Microbiology
https://read.qxmd.com/read/38740931/dynamics-of-measles-immunity-from-birth-and-following-vaccination
#5
JOURNAL ARTICLE
Wei Wang, Megan O'Driscoll, Qianli Wang, Sihong Zhao, Henrik Salje, Hongjie Yu
Measles remains a major threat to human health despite widespread vaccination. While we know that maternal antibodies can impair vaccine-induced immunity, the relative contributions of pre-existing immunity levels, maternal and infant characteristics on vaccine responses remain unclear, hampering evidence-based vaccination policy development. Here we combine serological data from 1,505 individuals (aged 0-12 years) in a mother-infant cohort and in a child cohort with empirical models to reconstruct antibody trajectories from birth...
May 13, 2024: Nature Microbiology
https://read.qxmd.com/read/38740930/reply-to-microbial-dark-matter-could-add-uncertainties-to-metagenomic-trait-estimations
#6
LETTER
Gabin Piton, Steven D Allison, Mohammad Bahram, Falk Hildebrand, Jennifer B H Martiny, Kathleen K Treseder, Adam C Martiny
No abstract text is available yet for this article.
May 13, 2024: Nature Microbiology
https://read.qxmd.com/read/38740929/microbial-dark-matter-could-add-uncertainties-to-metagenomic-trait-estimations
#7
LETTER
Ernest D Osburn, Steven G McBride, Michael S Strickland
No abstract text is available yet for this article.
May 13, 2024: Nature Microbiology
https://read.qxmd.com/read/38724757/understanding-the-biology-of-monkeypox-virus-to-prevent-future-outbreaks
#8
REVIEW
Bernard Moss
Historically, monkeypox (mpox) was a zoonotic disease endemic in Africa. However, in 2022, a global outbreak occurred following a substantial increase in cases in Africa, coupled with spread by international travellers to other continents. Between January 2022 and October 2023, about 91,000 confirmed cases from 115 countries were reported, leading the World Health Organization to declare a public health emergency. The basic biology of monkeypox virus (MPXV) can be inferred from other poxviruses, such as vaccinia virus, and confirmed by genome sequencing...
May 9, 2024: Nature Microbiology
https://read.qxmd.com/read/38714761/considering-the-host-in-host-pathogen-interactions
#9
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
May 7, 2024: Nature Microbiology
https://read.qxmd.com/read/38714760/metagenomics-to-improve-infectious-disease-diagnostics-in-low-and-middle-income-countries
#10
JOURNAL ARTICLE
Abdullahi Jamiu, Chrispin Chaguza
No abstract text is available yet for this article.
May 7, 2024: Nature Microbiology
https://read.qxmd.com/read/38714759/microbioraman-an-open-access-web-repository-for-microbiological-raman-spectroscopy-data
#11
LETTER
Kang Soo Lee, Zachary Landry, Awais Athar, Uria Alcolombri, Pratchaya Pramoj Na Ayutthaya, David Berry, Philippe de Bettignies, Ji-Xin Cheng, Gabor Csucs, Li Cui, Volker Deckert, Thomas Dieing, Jennifer Dionne, Ondrej Doskocil, Glen D'Souza, Cristina García-Timermans, Notburga Gierlinger, Keisuke Goda, Roland Hatzenpichler, Richard J Henshaw, Wei E Huang, Ievgeniia Iermak, Natalia P Ivleva, Janina Kneipp, Patrick Kubryk, Kirsten Küsel, Tae Kwon Lee, Sung Sik Lee, Bo Ma, Clara Martínez-Pérez, Pavel Matousek, Rainer U Meckenstock, Wei Min, Peter Mojzeš, Oliver Müller, Naresh Kumar, Per Halkjær Nielsen, Ioan Notingher, Márton Palatinszky, Fátima C Pereira, Giuseppe Pezzotti, Zdenek Pilat, Filip Plesinger, Jürgen Popp, Alexander J Probst, Alessandra Riva, Amr A E Saleh, Ota Samek, Haley M Sapers, Olga T Schubert, Astrid K M Stubbusch, Loza F Tadesse, Gordon T Taylor, Michael Wagner, Jing Wang, Huabing Yin, Yang Yue, Renato Zenobi, Jacopo Zini, Ugis Sarkans, Roman Stocker
No abstract text is available yet for this article.
May 7, 2024: Nature Microbiology
https://read.qxmd.com/read/38698178/oral-bacteria-relative-abundance-in-faeces-increases-due-to-gut-microbiota-depletion-and-is-linked-with-patient-outcomes
#12
JOURNAL ARTICLE
Chen Liao, Thierry Rolling, Ana Djukovic, Teng Fei, Vishwas Mishra, Hongbin Liu, Chloe Lindberg, Lei Dai, Bing Zhai, Jonathan U Peled, Marcel R M van den Brink, Tobias M Hohl, Joao B Xavier
The detection of oral bacteria in faecal samples has been associated with inflammation and intestinal diseases. The increased relative abundance of oral bacteria in faeces has two competing explanations: either oral bacteria invade the gut ecosystem and expand (the 'expansion' hypothesis), or oral bacteria transit through the gut and their relative increase marks the depletion of other gut bacteria (the 'marker' hypothesis). Here we collected oral and faecal samples from mouse models of gut dysbiosis (antibiotic treatment and DSS-induced colitis) and used 16S ribosomal RNA sequencing to determine the abundance dynamics of oral bacteria...
May 2, 2024: Nature Microbiology
https://read.qxmd.com/read/38689168/author-correction-a-dual-targeting-antifungal-is-effective-against-multidrug-resistant-human-fungal-pathogens
#13
Min Zhou, Longqiang Liu, Zihao Cong, Weinan Jiang, Ximian Xiao, Jiayang Xie, Zhengjie Luo, Sheng Chen, Yueming Wu, Xinying Xue, Ning Shao, Runhui Liu
No abstract text is available yet for this article.
April 30, 2024: Nature Microbiology
https://read.qxmd.com/read/38684912/author-correction-structure-of-geobacter-cytochrome-omcz-identifies-mechanism-of-nanowire-assembly-and-conductivity
#14
Yangqi Gu, Matthew J Guberman-Pfeffer, Vishok Srikanth, Cong Shen, Fabian Giska, Kallol Gupta, Yuri Londer, Fadel A Samatey, Victor S Batista, Nikhil S Malvankar
No abstract text is available yet for this article.
April 29, 2024: Nature Microbiology
https://read.qxmd.com/read/38684911/akkermansia-muciniphila-exoglycosidases-target-extended-blood-group-antigens-to-generate-abo-universal-blood
#15
JOURNAL ARTICLE
Mathias Jensen, Linn Stenfelt, Jennifer Ricci Hagman, Michael Jakob Pichler, Julia Weikum, Tine Sofie Nielsen, Annika Hult, Jens Preben Morth, Martin L Olsson, Maher Abou Hachem
Matching donor and recipient blood groups based on red blood cell (RBC) surface ABO glycans and antibodies in plasma is crucial to avoid potentially fatal reactions during transfusions. Enzymatic conversion of RBC glycans to the universal group O is an attractive solution to simplify blood logistics and prevent ABO-mismatched transfusions. The gut symbiont Akkermansia muciniphila can degrade mucin O-glycans including ABO epitopes. Here we biochemically evaluated 23 Akkermansia glycosyl hydrolases and identified exoglycosidase combinations which efficiently transformed both A and B antigens and four of their carbohydrate extensions...
April 29, 2024: Nature Microbiology
https://read.qxmd.com/read/38684910/gut-microorganism-enzymes-unlock-universal-blood
#16
JOURNAL ARTICLE
Timothy J Satchwell, Natalie Di Bartolo, Ashley M Toye
No abstract text is available yet for this article.
April 29, 2024: Nature Microbiology
https://read.qxmd.com/read/38671272/rethinking-the-burden-of-latent-tuberculosis-to-reprioritize-research
#17
JOURNAL ARTICLE
Marcel A Behr, Paul H Edelstein, Lalita Ramakrishnan
No abstract text is available yet for this article.
April 26, 2024: Nature Microbiology
https://read.qxmd.com/read/38671271/exceeding-expectations-out-in-the-cold-with-colwellia
#18
JOURNAL ARTICLE
Jody W Deming
No abstract text is available yet for this article.
April 26, 2024: Nature Microbiology
https://read.qxmd.com/read/38658786/age-and-sex-influence-antibody-profiles-associated-with-tuberculosis-progression
#19
JOURNAL ARTICLE
Leela R L Davies, Chuangqi Wang, Pia Steigler, Kathryn A Bowman, Stephanie Fischinger, Mark Hatherill, Michelle Fisher, Stanley Kimbung Mbandi, Miguel Rodo, Tom H M Ottenhoff, Hazel M Dockrell, Jayne S Sutherland, Harriet Mayanja-Kizza, W Henry Boom, Gerhard Walzl, Stefan H E Kaufmann, Elisa Nemes, Thomas J Scriba, Douglas Lauffenburger, Galit Alter, Sarah M Fortune
Antibody features vary with tuberculosis (TB) disease state. Whether clinical variables, such as age or sex, influence associations between Mycobacterium tuberculosis-specific antibody responses and disease state is not well explored. Here we profiled Mycobacterium tuberculosis-specific antibody responses in 140 TB-exposed South African individuals from the Adolescent Cohort Study. We identified distinct response features in individuals progressing to active TB from non-progressing, matched controls. A multivariate antibody score differentially associated with progression (SeroScore) identified progressors up to 2 years before TB diagnosis, earlier than that achieved with the RISK6 transcriptional signature of progression...
April 24, 2024: Nature Microbiology
https://read.qxmd.com/read/38653780/sars-and-synapses
#20
JOURNAL ARTICLE
Harris A Gelbard, Wesley Chiang
No abstract text is available yet for this article.
April 23, 2024: Nature Microbiology
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