Li-Juan Lv, Ji-Ying Wen, Yue Zhang, Ruo-Chun Guo, Hui Li, Zhou-Ting Yi, Tian-Wen He, Min-Chai Chen, Yang Chen, Xiao-Yan Wu, Sheng-Hui Li, Jian Kang, Ya-Ping Hou, Qiu-Long Yan, Ai-Hua Yin
Preeclampsia (PE), a pregnancy-specific syndrome, has been associated with the gut bacteriome. Here, to investigate the impact of the gut virome on the development of PE, we identified over 8,000 nonredundant viruses from the fecal metagenomes of 40 early-onset PE and 37 healthy pregnant women and profiled their abundances. Comparison and correlation analysis showed that PE-enriched viruses frequently connected to Blautia species enriched in PE. By contrast, bacteria linked to PE-depleted viruses were often the Bacteroidaceae members such as Bacteroides spp...
March 20, 2024: MSphere