journal
Journals Frontiers in Cardiovascular Me...

Frontiers in Cardiovascular Medicine

https://read.qxmd.com/read/38420267/ion-channel-trafficking-implications-in-heart-failure
#1
REVIEW
Jean-Baptiste Reisqs, Yongxia Sarah Qu, Mohamed Boutjdir
Heart failure (HF) is recognized as an epidemic in the contemporary world, impacting around 1%-2% of the adult population and affecting around 6 million Americans. HF remains a major cause of mortality, morbidity, and poor quality of life. Several therapies are used to treat HF and improve the survival of patients; however, despite these substantial improvements in treating HF, the incidence of HF is increasing rapidly, posing a significant burden to human health. The total cost of care for HF is USD 69.8 billion in 2023, warranting a better understanding of the mechanisms involved in HF...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38420266/editorial-imaging-in-structural-heart-interventions
#2
EDITORIAL
Martijn G H Vrijkorte, Omar K Khalique, Stamatios Lerakis, Martin J Swaans
No abstract text is available yet for this article.
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38420265/corrigendum-case-report-four-cases-of-cardiac-sarcoidosis-in-patients-with-inherited-cardiomyopathy-a-phenotypic-overlap-co-existence-of-two-rare-cardiomyopathies-or-a-second-hit-disease
#3
Hans Ebbinghaus, Laura Ueberham, Daniela Husser-Bollmann, Andreas Bollmann, Ingo Paetsch, Cosima Jahnke, Ulrich Laufs, Borislav Dinov
[This corrects the article DOI: 10.3389/fcvm.2023.1328802.].
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38420264/gender-differences-in-all-cause-and-cardiovascular-mortality-among-us-adults-from-nhanes-2005-2018
#4
JOURNAL ARTICLE
Ying Lv, Xiaodi Cao, Kai Yu, Jie Pu, Zhiguo Tang, Na Wei, Junkui Wang, Fuqiang Liu, Shangjian Li
BACKGROUND: Gender disparities in mortality have drawn great interest, with previous studies identifying various biological, social, and behavioral factors contributing to the observed gender differences. This study aims to identify the sources of gender disparities in mortality rates and quantify the extent to which these factors mediate the gender differences in all-cause mortality. METHODS: Data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2005 and 2018 were analyzed...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38420263/anti-hypertensive-effect-of-a-novel-angiotensin-ii-receptor-neprilysin-inhibitor-arni-s086-in-dss-rat-model
#5
JOURNAL ARTICLE
Jingchao Sun, Ying Xiao, Wenjie Xu, Wei Xing, Frank Du, Maozhi Tian, Danqi Xu, Yihua Ren, Xin Fang
INTRODUCTION: Angiotensin receptor-neprilysin inhibitor (ARNi), comprised of an angiotensin receptor blocker (ARB) and a neprilysin inhibitor (NEPi), has established itself as a safe and effective intervention for hypertension. S086 is a novel ARNi cocrystal developed by Salubris for the treatment of heart failure and hypertension. METHODS: Dahl Salt Sensitive (DSS) hypertensive rat model and telemetry system were employed in this study to investigate the anti-hypertensive efficacy of S086 and compare it with the first ARNi-LCZ696...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38420262/a-study-of-clinical-and-serological-correlation-of-early-myocardial-injury-in-elderly-patients-infected-with-the-omicron-variant
#6
JOURNAL ARTICLE
Xueying Yu, Xiaoguang Li, Shuai Xia, Lu Lu, Jiahui Fan, Ying Wang, Yan Fu, Chen Suo, Qiuhong Man, Lize Xiong
INTRODUCTION: Myocardial injury in elderly Omicron variant patients is a leading cause of severe disease and death. This study focuses on elucidating the clinical characteristics and potential risk factors associated with myocardial injury in elderly patients infected with the Omicron variant. METHODS: Myocardial injury was defined based on elevated cardiac troponin concentrations exceeding the 99th percentile upper reference limit. Among 772 elderly Omicron-infected patients, categorized into myocardial injury ( n  = 263) and non-myocardial injury ( n  = 509) groups...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38420261/case-report-giant-left-atrial-cystic-tumor-myxoma-or-intracardiac-blood-cyst
#7
Weizhang Xiao, Jing Qin, Jia Feng, Feng Jiang, Xinming Chen, Xiang Cao, Qun Xue, Jiahai Shi
BACKGROUND: Primary cardiac tumors are uncommon, with the majority being benign myxomas. Cystic myxoma, a particularly rare type of benign cardiac tumor, demands cautious differential diagnosis from other cardiac tumors. CASE SUMMARY: A 43-year-old male patient presenting with intermittent dyspnea was referred to our department for surgical evaluation. Transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) unveiled an intra-left atrial cyst, which was subsequently found to be blood-filled during a video-assisted microinvasive heart surgery...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38414927/polygenic-risk-score-predicts-all-cause-death-in-east-asian-patients-with-prior-coronary-artery-disease
#8
JOURNAL ARTICLE
Min Qin, Yonglin Wu, Xianhong Fang, Cuiping Pan, Shilong Zhong
INTRODUCTION: Coronary artery disease (CAD) is a highly heritable and multifactorial disease. Numerous genome-wide association studies (GWAS) facilitated the construction of polygenic risk scores (PRS) for predicting future incidence of CAD, however, exclusively in European populations. Furthermore, identifying CAD patients with elevated risks of all-cause death presents a critical challenge in secondary prevention, which will contribute largely to reducing the burden for public healthcare...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38414926/efficacy-and-safety-of-tongxinluo-capsule-for-angina-pectoris-of-coronary-heart-disease-an-overview-of-systematic-reviews-and-meta-analysis
#9
REVIEW
Liuying Li, Peimin Feng, Wenhua Zhou, Biao Luo, Lvyu Deng, Daohui Gan, Xiaohan Wu, Fengya Zhu, Xia Zhou
BACKGROUND: Tongxinluo capsule (TXLC) is a common drug for treating angina pectoris of coronary heart disease (CHD). In recent years, many systematic reviews (SRs) and meta-analyses (MAs) have reported the efficacy and safety of TXLC for improving angina symptoms in patients with CHD. We aimed to comprehensively evaluate the existing SRs and MAs of TXLC in treating angina pectoris of CHD, summarize the evidence quality, and provide scientific evidence and recommendations. METHODS: We searched seven databases for relevant SRs/MAs published up to 1 June 2023...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38414925/takotsubo-syndrome-and-atrial-myxoma-identifying-a-new-trigger-a-case-report
#10
Kevin Velarde-Acosta, Robert Sandoval, Luis Falcón-Quispe, William Efrain Anicama Lima, Roberto Baltodano-Arellano
Takotsubo syndrome (TTS) is a rare cardiomyopathy, but its prevalence is increasing due to the greater availability of diagnostic tools, whose pathophysiology is unknown; however, the evidence points to an excess of catecholamines that ends up generating cardiac stunning. The cause of excessive sympathetic discharge is multifactorial, and some tumors may be related to their origin. In this case report, we present a female patient with TTS whose only identified triggering factor was an atrial myxoma, which generated an unusual clinical presentation...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38414924/effect-of-on-pump-vs-off-pump-coronary-artery-bypass-grafting-in-patients-with-non-dialysis-dependent-severe-renal-impairment-propensity-matched-analysis-from-the-uk-registry-dataset
#11
JOURNAL ARTICLE
Daniel P Fudulu, Amerikos Argyriou, Rahul Kota, Jeremy Chan, Hunaid Vohra, Massimo Caputo, Mustafa Zakkar, Gianni D Angelini
INTRODUCTION: On-pump coronary artery bypass (ONCABG) grafting in patients with a pre-existing poor renal reserve is known to carry significant morbidity and mortality. There is limited controversial evidence on the benefit of off-pump coronary artery bypass (OPCABG) grafting in these high-risk groups of patients. We compared early clinical outcomes in propensity-matched cohorts of patients with non-dialysis-dependent pre-operative severe renal impairment undergoing OPCABG vs. ONCABG, captured in a large national registry dataset...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38414923/treatment-of-coronary-lesions-with-a-novel-crystalline-sirolimus-coated-balloon
#12
JOURNAL ARTICLE
Mehdi Madanchi, Adrian Attinger-Toller, Varis Gjergjizi, Irena Majcen, Giacomo M Cioffi, Angelika Epper, Eleonora Gnan, Tanja Koch, Yuan Zhi, Florim Cuculi, Matthias Bossard
BACKGROUND: There is mounting data supporting the use of drug-coated balloons (DCB) not only for treatment of in-stent restenosis (ISR), but also in native coronary artery disease. So far, paclitaxel-coated balloons represented the mainstay DCBs. The SeQuent® crystalline sirolimus-coated balloon (SCB) (B.Braun Medical Inc, Germany) represents a novel DCB, which allows a sustained release of the limus-drug. We evaluated its performance in an all-comer cohort, including complex coronary lesions...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38414922/case-report-primary-pericardial-angiosarcoma-a-rare-cause-of-cardiac-tamponade
#13
Ling-Yun Kong, Xiao-Zheng Cui, Wei Xiang, Xiu-Juan Wang, Fang Liu
Primary pericardial angiosarcoma is a rare malignancy of the pericardium with variable clinical features and imaging characteristics. Herein, we report a case of histopathologically confirmed pericardial angiosarcoma in a 66-year-old man. The patient developed cardiac tamponade in a short time period. The transthoracic echocardiography showed the presence of multiple irregular echodensities, heterogeneous in echogenicity, encasing the apex of both ventricles in the pericardial space, initially misinterpreted as pericardial effusion...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38414921/comorbidity-patterns-in-cardiovascular-diseases-the-role-of-life-stage-and-socioeconomic-status
#14
JOURNAL ARTICLE
Héctor A Cruz-Ávila, Fernando Ramírez-Alatriste, Mireya Martínez-García, Enrique Hernández-Lemus
Cardiovascular diseases stand as a prominent global cause of mortality, their intricate origins often entwined with comorbidities and multimorbid conditions. Acknowledging the pivotal roles of age, sex, and social determinants of health in shaping the onset and progression of these diseases, our study delves into the nuanced interplay between life-stage, socioeconomic status, and comorbidity patterns within cardiovascular diseases. Leveraging data from a cross-sectional survey encompassing Mexican adults, we unearth a robust association between these variables and the prevalence of comorbidities linked to cardiovascular conditions...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38414920/editorial-arrhythmias-in-women
#15
EDITORIAL
Hector Barajas-Martinez, Michael Shehata, Yang Liu
No abstract text is available yet for this article.
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38414919/people-living-with-hiv-display-increased-anti-apolipoprotein-a1-auto-antibodies-inflammation-and-kynurenine-metabolites-a-case-control-study
#16
JOURNAL ARTICLE
Miguel A Frias, Sabrina Pagano, Nasim Bararpour, Jonathan Sidibé, Festus Kamau, Vanessa Fétaud-Lapierre, Peter Hudson, Aurélien Thomas, Sandrine Lecour, Hans Strijdom, Nicolas Vuilleumier
OBJECTIVE: This study aimed to study the relationship between auto-antibodies against apolipoprotein A1 (anti-apoA1 IgG), human immunodeficiency virus (HIV) infection, anti-retroviral therapy (ART), and the tryptophan pathways in HIV-related cardiovascular disease. DESIGN: This case-control study conducted in South Africa consisted of control volunteers ( n  = 50), people living with HIV (PLWH) on ART ( n  = 50), and untreated PLWH ( n  = 44)...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38414918/editorial-implementation-of-digital-health-intervention-on-mobile-devices-to-support-cardiovascular-disease-healthcare-among-public-health
#17
EDITORIAL
Han Feng, Lingzhi Li, Chaoran Hu, Hua He, Nassir Marrouche, Xiang Li
No abstract text is available yet for this article.
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38410247/neuromuscular-manifestations-of-wild-type-transthyretin-amyloidosis-a-review-and-single-center-s-experience
#18
REVIEW
Sasha A Živković, David Lacomis, Prem Soman
Transthyretin amyloidosis (ATTR) is a condition defined by accumulation of insoluble transthyretin amyloid deposits in multiple organs, especially in the peripheral nerve and heart muscle. ATTR may result from transthyretin mutations (variant ATTR or ATTRv) or may occur with normal transthyretin genotype (wild type ATTR or ATTRwt). ATTRwt was previously known as "senile amyloidosis" and causes cardiomyopathy which may lead to heart failure with a preserved ejection fraction, affecting predominantly elderly men...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38410246/deep-learning-denoising-reconstruction-for-improved-image-quality-in-fetal-cardiac-cine-mri
#19
JOURNAL ARTICLE
Thomas M Vollbrecht, Christopher Hart, Shuo Zhang, Christoph Katemann, Alois M Sprinkart, Alexander Isaak, Ulrike Attenberger, Claus C Pieper, Daniel Kuetting, Annegret Geipel, Brigitte Strizek, Julian A Luetkens
PURPOSE: This study aims to evaluate deep learning (DL) denoising reconstructions for image quality improvement of Doppler ultrasound (DUS)-gated fetal cardiac MRI in congenital heart disease (CHD). METHODS: Twenty-five fetuses with CHD (mean gestational age: 35 ± 1 weeks) underwent fetal cardiac MRI at 3T. Cine imaging was acquired using a balanced steady-state free precession (bSSFP) sequence with Doppler ultrasound gating. Images were reconstructed using both compressed sensing (bSSFP CS) and a pre-trained convolutional neural network trained for DL denoising (bSSFP DL)...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38410245/circulating-biomarkers-in-the-diagnosis-and-prognosis-of-immune-checkpoint-inhibitor-related-myocarditis-time-for-a-risk-based-approach
#20
REVIEW
Gillian Murtagh, Christopher deFilippi, Qiong Zhao, Ana Barac
Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block immune checkpoints and therefore activate immune cells, allowing them to recognize and attack cancer cells. ICIs have revolutionized oncology practice, but their use has been complicated by immune-related adverse events (irAEs). Of cardiovascular (CV) irAEs, ICI-related myocarditis has received significant attention due to high mortality rates, ranging from 25% to 50%, despite its overall low incidence. Establishing the early diagnosis of ICI-myocarditis is important for early initiation of steroids and consideration of hospitalization in patients who are at risk for hemodynamic compromise and need high acuity care in a tertiary setting...
2024: Frontiers in Cardiovascular Medicine
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