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Burns and Trauma

Ke Li, Fabio Nicoli, Wen Jing Xi, Zheng Zhang, Chunxiao Cui, Ahmed Al-Mousawi, Alberto Balzani, Yun Tong, Yixin Zhang
Background: Keloids are the result of abnormal wound healing and often are subject to infections and recurrent inflammation. We present a study conducted with a 1470 nm diode laser using an intralesional optical fiber device for the treatment of inflamed keloid scars. We evaluate its efficacy as a novel alternative method to decrease keloid infection and inflammation. Methods: The patients who underwent 1470 nm laser treatment from February 2016 to February 2018 at the plastic and reconstructive surgery department of the Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University with keloid accompanying serious local infection and fester were included...
2019: Burns and Trauma
Xiujun Fu, Jiying Dong, Shen Wang, Min Yan, Min Yao
Traumatic scarring is one of the most common complications after soft tissue injury caused by burns and trauma, which affects tens of millions of people worldwide every year. Traumatic scars diminish the quality of life due to disfigurement, symptoms of pain and itch, and restricted motion. The pathogenesis and pathophysiology of traumatic scar remain elusive. The management for traumatic scars is comprised of surgical and non-surgical interventions such as pressure therapy, silicone, corticosteroid, and radiotherapy, which are chosen by clinicians based on the physical examinations of scars...
2019: Burns and trauma
Henry Tan Chor Lip, Jih Huei Tan, Mathew Thomas, Farrah-Hani Imran, Tuan Nur' Azmah Tuan Mat
Background: Prognostic measures to determine burn mortality are essential in evaluating the severity of individual burn victims. This is an important process of triaging patients with high risk of mortality that may be nursed in the acute care setting. Malaysian burn research is lacking with only one publication identified which describes the epidemiology of burn victims. Therefore, the objective of this study was to go one step further and identify the predictors of burn mortality from a Malaysian burns intensive care unit (BICU) which may be used to triage patients at higher risk of death...
2019: Burns and trauma
Rachael Zoe Murray, Zoe Elizabeth West, Allison June Cowin, Brooke Louise Farrugia
There is a vast number of treatments on the market for the management of wounds and burns, representing a multi-billion dollar industry worldwide. These include conventional wound dressings, dressings that incorporate growth factors to stimulate and facilitate the wound healing process, and skin substitutes that incorporate patient-derived cells. This article will review the more established, and the recent advances in the use of biomaterials for wound healing therapies, and their future direction.
2019: Burns and Trauma
Hao Lu, Long Yuan, Xunzhou Yu, Chengzhou Wu, Danfeng He, Jun Deng
Wound management is a major global challenge and a big financial burden to the healthcare system due to the rapid growth of chronic diseases including the diabetes, obesity, and aging population. Modern solutions to wound management include hydrogels that dissolve on demand, and the development of such hydrogels is of keen research interest. The formation and subsequent on-demand dissolution of hydrogels is of keen interest to scientists and clinicians. These hydrogels have excellent properties such as tissue adhesion, swelling, and water absorption...
2018: Burns and Trauma
Si-Liang Xue, Kai Liu, Ornella Parolini, Yue Wang, Li Deng, Yong-Can Huang
Background: The lower third of the nose is one of the most important cosmetic units of the face, and its reconstructive techniques remain a big challenge. As an alternative approach to repair or regenerate the nasal tissue, the biomaterial-based strategy has been extensively investigated. The aim of this study is to determine the safety and efficacy of human acellular amniotic membrane (HAAM) to repair the full-thickness defects in the lower third of the nose in humans. Methods: In this study, 180 patients who underwent excision of skin lesions of the lower third of the nose from 2012 to 2016 were included; of the patients, 92 received HAAM and Vaseline gauze treatments, and the other 88 patients received Vaseline gauze treatment only...
2018: Burns and Trauma
Craig A McBride, Roy M Kimble, Kellie A Stockton
Background: This is a parallel three-arm prospective randomised controlled trial (RCT) comparing Algisite™ M, Cuticerin™, and Sorbact® as donor site dressings in paediatric split-thickness skin grafts (STSG). All three were in current use within the Pegg Leditschke Children's Burn centre (PLCBC), the largest paediatric burns centre in Queensland, Australia. Our objective was to find the best performing dressing, following on from previous trials designed to rationalise dressings for the burn wound itself...
2018: Burns and Trauma
Janine M Duke, Sean M Randall, Thirthar P Vetrichevvel, Sarah McGarry, James H Boyd, Suzanne Rea, Fiona M Wood
Background: Burns are a devastating injury that can cause physical and psychological issues. Limited data exist on long-term mental health (MH) after unintentional burns sustained during childhood. This study assessed long-term MH admissions after paediatric burns. Methods: This retrospective cohort study included all children (< 18 years) hospitalised for a first burn ( n  = 11,967) in Western Australia, 1980-2012, and a frequency matched uninjured comparison cohort ( n  = 46,548)...
2018: Burns and Trauma
Thirthar P Vetrichevvel, Sean M Randall, Fiona M Wood, Suzanne Rea, James H Boyd, Janine M Duke
Background: A number of studies report high prevalence of mental health conditions among burn patients. However there is a need to understand differences in the temporal relationship between mental health conditions and intentional and unintentional burns to hasten psychological prevention and intervention. This study aims to compare the socio-demographic profile, burn characteristics and pre- and post-burn psychiatric morbidity of burn patients by intent-of-injury. Methods: De-identified linked hospital, death and mental health (MH) case registry data of burn patients hospitalised in Western Australia between 1 January 1980 and 30 June 2012 were analysed...
2018: Burns and Trauma
Yichao Xu, Xinyuan Jin, Xiaonan Shao, Feng Zheng, Hong Zhou
Background: Severe burn sepsis can lead to high mortality. We explored the valuable prognostic indicators for severe burn sepsis with inhalation lesion. Methods: Thirty-eight severe burn patients with sepsis who were admitted to the Third Affiliated Hospital of Soochow University from August 2014 to December 2017 were retrospectively analyzed. Among them, 22 patients were assigned to the death group and 16 patients to the survival group. Their general information, vital signs, and blood index including serum procalcitonin (PCT) and C-reactive protein (CRP) levels at admission, diagnosis of sepsis, and 1-week post-diagnosis of sepsis were compared...
2018: Burns and trauma
Denisse Mendez-Romero, Audra T Clark, Alana Christie, Steven E Wolf
Background: Severe burn is associated with significant changes in body weight due to resuscitation volumes, fluid shifts, a hypermetabolic state, prolonged bed rest, and caloric intake. Our goal was to quantify and describe trends in weight change in patients with burns of all severities under modern treatment conditions and to identify the time points at which these changes occur. Methods: An institutional review board-approved chart review was conducted of acute burn patients treated at an American Burn Association-verified regional burn center from February 2016 to November 2016...
2018: Burns and Trauma
Peng-Ran Du, Hong-Ting Lu, Xi-Xiang Lin, Li-Feng Wang, Yan-Xia Wang, Xiao-Ming Gu, Xiao-Zhi Bai, Ke Tao, Jing-Jun Zhou
Background: The molecular pattern of severe burn-induced acute lung injury, characterized by cell structure damage and leukocyte infiltration, remains unknown. This study aimed to determine whether calpain, a protease involved in both processes, mediates severe burn-induced acute lung injury. Methods: Rats received full-thickness scald burns covering 30% of the total body surface area, followed by instant fluid resuscitation. MDL28170 (Tocris Bioscience), an inhibitor of calpain, was given intravenously 1 h before or after the scald burn...
2018: Burns and Trauma
Kaiyang Lv, Zhaofan Xia
Following injury, Asian skin has a tendency toward hyperpigmentation and scar formation than Caucasians. A standardized algorithm tailored to Asian patients, especially Chinese patients, is in great demand. Twelve independent, self-selected academic and military physicians from the department of burn/trauma, plastic surgery and dermatology with extensive experience in treating scars were assembled on January 17, 2015, establishing the consensus panel. This consensus was then appraised, drafted, reviewed, and finalized during the following 3 years, aiming to standardize and improve scar prevention and treatment in China...
2018: Burns and trauma
Si Jack Chong, Yee Onn Kok, Rosanna Xiang Ying Tay, Desai Suneel Ramesh, Kok Chai Tan, Bien Keem Tan
Background: Inhalational injury is a major cause of morbidity and mortality in burns patients. This study aims to analyse the clinical outcomes, complications and bacteriology of inhalational burn patients. Methods: A prospective study was done on consecutive admissions to Burn Department, Singapore General Hospital over 15 months from January 2015 to March 2016. Presence of inhalational injury, demographics, complications and outcomes was recorded. Diagnosis of inhalational injury was based on history, symptoms and nasoendoscopy...
2018: Burns and Trauma
Hannah Zhao-Fleming, Audrey Hand, Kelly Zhang, Robert Polak, Armand Northcut, Daron Jacob, Sharmila Dissanaike, Kendra P Rumbaugh
The USA is currently going through an opioid crisis, associated with tremendous economic and societal impacts. In response to this crisis, healthcare professionals are looking for alternative pain management methods, and non-steroidal anti-inflammatory drugs (NSAIDs) are a sensible choice because of their effectiveness after surgical procedures. However, before surgeons start prescribing NSAIDs in place of opioids, it is crucial to first understand their potential post-surgical complications. The goal of this review is to summarize the data obtained through both animal and human studies, which suggest how a dramatic increase in NSAID use may affect these post-surgical complications...
2018: Burns and Trauma
Dmitry Zavlin, Vishwanath Chegireddy, Stefanos Boukovalas, Anna M Nia, Ludwik K Branski, Jeffrey D Friedman, Anthony Echo
Background: Previous reports individually identified different factors that predict death after burns. The authors employed the multi-center American Burn Association's (ABA) National Burn Repository (NBR) to elucidate which parameters have the highest negative impact on burn mortality. Methods: We audited data from the NBR v8.0 for the years 2002-2011 and included 137,061 patients in our study. The cases were stratified into two cohorts based on the primary outcome of death/survival and then evaluated for demographic data, intraoperative details, and their morbidity after admission...
2018: Burns and trauma
Laura Pompermaier, Moustafa Elmasry, Islam Abdelrahman, Mats Fredrikson, Folke Sjöberg, Ingrid Steinvall
Background: Disparity between medical treatment for men and women has been recorded worldwide. However, it is difficult to find out if the disparities in both the use of resources and outcome depend entirely on sex-related discrimination. Our aim was to investigate if there are differences in burn treatments between the sexes. Methods: All patients admitted with burns to Linköping University Hospital during the 16-year period 2000-2015 were included. Interventions were prospectively recorded using the validated Burn SCoring system (BSC)...
2018: Burns and Trauma
Jong Dae Kim, Suk Joon Oh, Sun Gyu Kim, Song Vogue Ahn, Yu Jin Jang, Ban Seok Yang, Ji Yun Jeong, Kwang Jo Kim
Background: This study aimed to investigate the difference between ultrasonographic findings of normal skin and those of re-epithelialized skin after partial-thickness burns and to evaluate the relationship between these findings and clinical outcomes. Methods: This study retrospectively analysed the ultrasound images of re-epithelialized skin after partial-thickness burns and contralateral normal skin from January 2016 to December 2016. A total of 155 lesions from 148 patients were analysed with ultrasound images, and healing time was documented...
2018: Burns and Trauma
Cheng Hean Lo, Simone H Nothdurft, Hye-Sung Park, Eldho Paul, James Leong
Background: The purpose of this study is to present our experience with the modified pins and rubber band traction system, discuss problems encountered, and make recommendations to optimize outcomes. Methods: Data was collected prospectively from November 2013 to March 2017 at a tertiary referral hospital in Melbourne, Australia. Patients with closed complex proximal interphalangeal joint fracture dislocations that were considered unsuitable for other surgical options were included in the study...
2018: Burns and Trauma
Akhtar Bibi, Sundas Kalim, Muhammad Adnan Khalid
Background: Post-traumatic stress disorder (PTSD) is one of the major psychological disorders developed after burn injuries, though this subject of burn injuries and their destructive chronic psychological impact are not considered as thoughtfully in developing countries like Pakistan. Hence, the current study investigated the relationship between PTSD symptoms and resilience among burn patients in Pakistan, exploring the variance occurrence of the two variables concerning male burn patients and female burn patients...
2018: Burns and Trauma
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