Cristina Quispe, Jesús Herrera-Bravo, Khushbukhat Khan, Zeeshan Javed, Prabhakar Semwal, Sakshi Painuli, Senem Kamiloglu, Miquel Martorell, Daniela Calina, Javad Sharifi-Rad
Medicinal applications of turmeric-derived curcumin have been known to mankind for long ages. Its potential in managing "cystic fibrosis" has also been evaluated. This autosomal recessive genetic disease is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) which involves an impaired secretion of chloride ions and leads to hypersecretion of thick and sticky mucus and serious complications including airway obstruction, chronic lung infection, and inflammatory reactions. This narrative review aims to highlight the available evidence for the efficacy of curcumin nanoformulations in its potential treatment of cystic fibrosis...
July 29, 2022: Progress in Biomaterials