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Value in Health Regional Issues

Alexia Kieffer, Celine Hoestlandt, Yaneth Gil-Rojas, Anaïs Broban, Camilo Castañeda-Cardona, Diego Rosselli
OBJECTIVES: To evaluate the public health benefits and economic value of live-attenuated yellow fever (YF) 17D vaccine in Colombia. METHODS: A decision tree model was used to assess the theoretical impact of routine YF vaccination of 1-year-olds (no "catch-up") during the interepidemic period from 1980 to 2002, avoiding capturing the impact of YF vaccine introduction in 2003. The vaccine was assumed to be 99% effective, to provide lifetime protection, and to cover 85% of the target population...
April 8, 2019: Value in Health Regional Issues
Lindsey Hiebert, Robert Hecht, Shan Soe-Lin, Rosmawati Mohamed, Fatiha H Shabaruddin, Syed Mukhtar Syed Mansor, Maznah Dahlui, Amirah Azzeri, Scott A McDonald
BACKGROUND: In Malaysia, more than 330 000 individuals are estimated to be chronically infected with hepatitis C virus (HCV), but less than 2% have been treated to date. OBJECTIVES: To estimate the required coverage and costs of a national screening strategy to inform the launch of an HCV elimination program. METHODS: We designed an HCV screening strategy based on a "stepwise" approach. This approach relied on targeting of people who inject drugs in the early years, with delayed onset of widespread general population screening...
March 25, 2019: Value in Health Regional Issues
Jing Wu, Yi Qu, Ke Wang, Yu Chen
OBJECTIVES: To estimate annual healthcare resource utilization and direct medical costs for patients with osteoporotic fractures in China. METHODS: Data were obtained from the Tianjin Urban Employee Basic Medical Insurance database (2008-2011). Included patients were 50 years or older with one or more diagnoses of osteoporotic fractures between 2009 and 2010. The annual healthcare resource utilization and direct medical costs were estimated. Regression model was applied to identify factors associated with the direct medical costs...
March 22, 2019: Value in Health Regional Issues
Shima Shahjouei, Alireza Vafaei Sadr, Soheila Khorasani, Farideh Nejat, Zohreh Habibi, Ali Akbari Sari
BACKGROUND: Assessment of health-related quality of life (HRQOL or utility) is a complex issue especially in children with temporary health states. OBJECTIVES: To assess the utility of prone positioning as a prophylactic postsurgical approach with the aid of 5 frequently used general instruments. METHODS: Visual analogue scale (VAS), time trade-off (TTO), modified TTO (m-TTO), standard gamble (SG), and chain of gambles (ChGs) instruments and interview with the parent caregivers were used to measure the HRQOL (utility value) of patients who were admitted in the surgical wards of Children's Medical Center Hospital between July and November 2015...
March 18, 2019: Value in Health Regional Issues
Zahra Azad, Fatemeh Teimouri, Ali Akbarisari, Abdoulreza Esteghamati, Shekoufeh Nikfar
OBJECTIVES: To examine the budget impact of introducing the RotaTeq® vaccine (Merck and Co Inc, West Point, PA) to the national immunization program in Iran. METHODS: The pre- and postvaccine introduction costs were compared. The total annual costs included the vaccination and diarrhea treatment costs. The health outcome was the estimated annual cases of the disease. To evaluate the net budget impact, the annual prevaccine introduction cost was reduced from the postvaccine introduction cost...
March 14, 2019: Value in Health Regional Issues
Sara Hamdi Abdulrhim, Rana Ahmed Saleh, Mohamed Abdelazim Mohamed Hussain, Hend Al Raey, Ahmed Hussein Babiker, Nadir Kheir, Ahmed Awaisu
BACKGROUND: Diabetes mellitus is highly prevalent in the Middle East and the burden associated with it is dramatically increasing. Pharmacists working in collaborative healthcare teams have an important role to improve outcomes in the primary care of diabetes. OBJECTIVES: To evaluate the impact of a collaborative pharmaceutical care service (CPCS) on improving outcomes among patients with diabetes in a primary care setting. METHODS: This was a retrospective, multiple time series study involving patients attending an ambulatory diabetes clinic at Qatar Petroleum Healthcare Center in Dukhan, Qatar...
March 12, 2019: Value in Health Regional Issues
Daniela María Paredes Fernández, Rony Christian Lenz Alcayaga
BACKGROUND: Despite the growing interest in risk-sharing agreements as appropriate payment mechanisms for high-cost treatments, few practical resources facilitate their adoption. OBJECTIVE: To identify and propose lessons for designing and implementing these models based on a review of the international experience, and to offer a concise model based on these lessons. METHODS: The steps of the Joanna Briggs Institute were adopted, which included identifying the concept and its relevant variants in scientific and gray literature...
March 11, 2019: Value in Health Regional Issues
P N Aguiar, Felipe Roitberg, Carmelia Maria Noia Barreto, Jacob J Adashek, Auro Del Giglio, Gilberto L Lopes
BACKGROUND: Over the past 5 years, 55 new anticancer drugs have been launched worldwide. Considering the increasing costs of innovative treatments, both the number and the relevance of cost-effectiveness analyses have increased, meaningfully supporting decision making by stakeholders and policy makers. Notably, cost-effective treatments remain unavailable to patients because they are still unaffordable for a multitude of payers. OBJECTIVES: To discuss the differences between cost effectiveness and affordability...
March 8, 2019: Value in Health Regional Issues
Todd Gilmer, Jose Luis Burgos, Maria Cecilia, Adriana Vargas-Ojeda
BACKGROUND: The prevalence of diabetes has increased substantially in Mexico over the last 40 years, leading to significant impacts on population health and the healthcare system. Technology-based solutions may improve diabetes outcomes in areas where lack of efficient transportation creates barriers to care. OBJECTIVES: To estimate the lifetime cost effectiveness of a technology-based diabetes care management program from the perspective of the Mexican healthcare system...
March 8, 2019: Value in Health Regional Issues
Alena Strizek, Chee-Jen Chang, Wesley Furnback, Bruce Wang, Jérémie Lebrec, Thomas Lew
OBJECTIVES: To quantify the incremental burden of patients with type 2 diabetes mellitus (T2DM) and a hypoglycemic event in Taiwan using the National Health Insurance Research Database. METHODS: Data from 2000 through 2013 with an index period of 2001 through 2012 from the National Health Insurance Research Database's 2-million-patient sample were used. Using a nested case-control study design, patients were indexed if they reported a diagnosis of T2DM during the index period...
February 15, 2019: Value in Health Regional Issues
Alen Marijam, Jan Olbrecht, Alev Ozakay, Volkan Eken, Kinga Meszaros
BACKGROUND: The 13-valent pneumococcal conjugate vaccine (PCV13) is used for universal infant vaccination in Turkey. OBJECTIVES: To assess the cost effectiveness of replacing PCV13 with pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV). METHODS: A Markov cohort model with monthly cycles following 1 cohort of infants over a 10-year time horizon was used. Local input parameters were obtained from published sources and expert consultation whenever possible...
February 15, 2019: Value in Health Regional Issues
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February 6, 2019: Value in Health Regional Issues
Andrés Freiberg, Jorge Nicolás Lafferriere, Martín Zambrano
Argentina considers its first National HTA Agency (AGNET) amidst expectations that it would stop "the scourge of judicialization". We suspect this argument is counterintuitive: the creation of HTA Agencies, or Health Benefits Packages in the Region, whatever their breadth, have so far failed to contain judicialisation by themselves. We discuss that judicialization thrives not only because of the laws of the land, but also because the design and creation of these technical Agencies, informing benefits lists, has been largely divorced from the more difficult task of seeking system-wide priority-setting (PS) processes and institutions, capable of eliciting the social values on which difficult coverage decisions should rest...
January 28, 2019: Value in Health Regional Issues
Pimwara Tanvejsilp, Suthira Taychakhoonavudh, Usa Chaikledkaew, Nathorn Chaiyakunapruk, Surachat Ngorsuraches
OBJECTIVES: To describe the process, challenges, and future direction of health technology assessment (HTA), focusing on the drug selection of the National List of Essential Medicines (NLEM) in Thailand. METHODS: Literature and government documents were reviewed and analyzed by authors with experiences in HTA and drug policy in the country. RESULTS: The structure of HTA and its process in the drug selection of the NLEM were described, followed by the outcomes of the use of HTA...
January 11, 2019: Value in Health Regional Issues
Slaveyko N Djambazov, Maria Daniela Giammanco, Lara Gitto
BACKGROUND: The relevance of studies focusing on patient satisfaction becomes imperative for patients with cancer, who often face major changes in their lifestyles. Their perceived uncertainty in illness and their personal experiences with the services received are crucial factors for a qualitatively adequate assistance. OBJECTIVES: To assess the determinants of patient satisfaction, using a sample of 306 Bulgarian oncology outpatients. METHODS: The hypotheses tested concern the extent to which patient satisfaction depends on the uncertainty in illness; the patients' assessment of technical and interpersonal skills of nurses and medical staff; the information provision; and some organizational aspects...
January 11, 2019: Value in Health Regional Issues
Ana Inés Galain, Juan José Dapueto, Ramón Alvarez, Liliana Gadola
BACKGROUND: Patients on dialysis report high levels of symptom burden. The association of these symptoms may have an increased deleterious effect on the patients' well-being. OBJECTIVE: This study aimed to assess the prevalence of symptoms, to identify symptom clusters, and to describe the impact of concurrent symptoms on physical and emotional well-being in a sample of dialysis patients. METHODS: Data of the first assessment of a longitudinal study aimed to assess patient-reported outcomes in dialysis were included here...
January 10, 2019: Value in Health Regional Issues
Shima Shahjouei, Alireza Vafaei Sadr, Soheila Khorasani, Farideh Nejat, Zohreh Habibi, Ali Akbari Sari
BACKGROUND: Health-related quality of life (utility) measures are essential components of effectiveness analyses. The health-related quality of life of health states in pediatric patients who underwent spinal surgery have not been reported previously. OBJECTIVES: To estimate the utility of complications after spinal surgeries and side effects of acetazolamide administration. METHODS: Parent caregivers, nurses, neurosurgeons, and orthopedists were interviewed as proxies to evaluate the preference of health conditions in pediatric patients who underwent intradural surgeries...
January 9, 2019: Value in Health Regional Issues
Federico Liberman, Jorge Elgart, Ingrid Strusberg
OBJECTIVES: To estimate the following: (1) the avoidable cost of biologic (bDMARDs) and conventional synthetic Rheumatoid Arthritis (RA) modifying antirheumatic drugs (csDMARDs) during controlled clinical trials (CCTs), their extension period, and for bDMARDs in post study drug programs; and (2) to evaluate the impact on health insurances. METHODS: We analyzed 13 CCTs (233 patients) that evaluated bDMARDs. Avoidable cost was what the health insurance should have paid if the patient had not received the medication from the CCT sponsor and was estimated with a micro-costing approach (bottom-up method)...
January 8, 2019: Value in Health Regional Issues
Marcos Bosi Ferraz, Elene Paltrinieri Nardi, Alessandro Gonçalves Campolina
BACKGROUND: The 6-dimensional health state short form (SF-6D) is a health preference measure used in economic evaluations of many treatments. OBJECTIVES: To compare the results provided by the SF-6D index, when applied to a representative sample of the Brazilian population, using Brazilian and UK preference weights. METHODS: Five thousand individuals were assessed in the 5 regions of Brazil. Preference measures in healthcare were assessed using the SF-6D Brazil, version 2002...
January 8, 2019: Value in Health Regional Issues
Valerie S Hughes, André Luis Ferreira De Azeredo-Da-Silva, Ana L Hincapie
BACKGROUND: An increasing awareness of the importance of health economics and outcomes research (HEOR) skills has been reported in Latin America. There is, however, no published study directly assessing perceived knowledge levels and knowledge gaps on specific HEOR topics among professionals and students in the region. OBJECTIVES: To assess perceived HEOR knowledge levels and identify knowledge gaps in Latin America. METHODS: An online needs assessment survey was developed to quantify perceived HEOR knowledge levels and identify knowledge gaps...
January 8, 2019: Value in Health Regional Issues
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