J Maximilian Fels, Saad Khan, Ryan Forster, Karin A Skalina, Surksha Sirichand, Amy S Fox, Aviv Bergman, William B Mitchell, Lucia R Wolgast, Wendy A Szymczak, Robert H Bortz, M Eugenia Dieterle, Catalina Florez, Denise Haslwanter, Rohit K Jangra, Ethan Laudermilch, Ariel S Wirchnianski, Jason Barnhill, David L Goldman, Hnin Khine, D Yitzchak Goldstein, Johanna P Daily, Kartik Chandran, Libusha Kelly
The Bronx was an early epicenter of the COVID-19 pandemic in the USA. We conducted temporal genomic surveillance of 104 SARS-CoV-2 genomes across the Bronx from March October 2020. Although the local structure of SARS-CoV-2 lineages mirrored those of New York City and New York State, temporal sampling revealed a dynamic and changing landscape of SARS-CoV-2 genomic diversity. Mapping the trajectories of mutations, we found that while some became 'endemic' to the Bronx, other, novel mutations rose in prevalence in the late summer/early fall...
July 13, 2022: Cold Spring Harbor Molecular Case Studies