Muhammed A M Hammad, Adriana Rush, Charles A Loeb, Jasmin Banton, Elia Abou Chawareb, Narmina Khanmammadova, Rafael R Gevorkyan, David W Barham, Faysal A Yafi, Lawrence C Jenkins
INTRODUCTION: Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system and is widely recognized as a disease primarily affecting women. The relationship between MS and hypogonadism is complex and not fully understood, with recent evidence showing that hypogonadism may have a significant impact on the quality of life and disease progression of patients with MS. OBJECTIVES: This review aims to provide an overview of the current knowledge regarding the relationship between MS and hypogonadism, including the mechanisms underlying this relationship; the effects of hypogonadism on patients with MS; and the potential benefits and drawbacks of testosterone replacement therapy for patients with MS and hypogonadism...
January 5, 2024: Sexual Medicine Reviews