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Autopsy & Case Reports

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https://read.qxmd.com/read/30775334/erratum
#1
(no author information available yet)
[This corrects the article DOI: 10.4322/acr.2018.029.].
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775333/pulmonary-histoplasmoma-a-disguised-malady
#2
Paulo Marcelo Pontes Gomes de Matos, Aloisio Felipe-Silva, José Pinhata Otoch
Histoplasmosis is a mycosis caused by the dimorphic fungus, Histoplasma capsulatum , which is transmitted via dust and aerosols. Lung involvement is the most common, with a varied clinical presentation. Although it is not the only source of infection, H. capsulatum is frequently found in bat guano, which is the reason why it is highly prevalent among caving practitioners. The solitary histoplasmoma of the lung is an unusual and chronic manifestation of this entity, which mimics, or at least is frequently misconstrued, as a malignancy...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775332/university-autopsy-service-a-high-powered-tool-for-medical-teaching-and-scientific-research-a-testimony
#3
EDITORIAL
Carlos Augusto Pasqualucci
No abstract text is available yet for this article.
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775331/nominata-of-the-reviewers-of-the-volume-8-2018
#4
(no author information available yet)
No abstract text is available yet for this article.
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775330/sebaceous-carcinoma-in-a-mature-teratoma-of-the-ovary
#5
Renata Bernardini de Lima, Juliana Elizabeth Jung, Sérgio Ossamu Ioshii, Roger Mitsuo Kami
The finding of a sebaceous carcinoma in a mature teratoma is rare in human pathology, with fewer than 10 cases currently reported in the literature. In this article, we report a case of sebaceous carcinoma in a mature teratoma of the ovary in a 59-year-old patient and discuss its histological findings.
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775329/myxomatous-degeneration-of-the-mitral-valve
#6
Felippe Lazar Neto, Laís Costa Marques, Vera Demarchi Aiello
No abstract text is available yet for this article.
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775328/intravascular-large-b-cell-lymphoma-the-great-imitator
#7
Katherine Ann Devitt, Juli-Anne Gardner
Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma with an estimated incidence of less than one per million. Unlike other hematopoietic malignancies, lymphadenopathy and hepatosplenomegaly are uncommon, and patients typically present with nonspecific symptoms. IVLBCL presents a diagnostic challenge and patients are usually diagnosed late in the disease course, if at all, and the prognosis is poor. The differential diagnosis is broad, and physicians often pursue multiple diagnostic possibilities during patient workup...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775327/ameloblastoma-with-distinctive-granular-cell-pattern-an-8-case-study
#8
Ana Maria Hoyos Cadavid, Tathyane Harumi Nakajima Teshima, Clóvis Antônio Lopes Pinto, Cláudia Malheiros Coutinho Camillo, Silvia Vanessa Lourenço
Ameloblastoma with granular cell pattern (AGC) is classified as an unusual histological subtype of solid/multicystic ameloblastoma, characterized by granular changes in stellate-like cells located within the inner portion of the epithelial follicles. Studies have revealed that lysosomal overload causes cytoplasmic granularity; however, the mechanism involved remains poorly understood. Here we report on eight cases of granular cell ameloblastoma, in the posterior region of the mandible. The age of the patients included in this case series ranged from 35 -64 years old and 87...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775326/late-stillbirth-due-to-listeriosis
#9
Antonio Segado-Arenas, Lidia Atienza-Cuevas, José Roman Broullón-Molanes, Moisés Rodríguez-González, Simón Pedro Lubián-López
Listeriosis is a sporadic infectious disease, which affects high-risk populations, such as the elderly, pregnant women, newborns, and immunocompromised patients. During pregnancy, listeriosis usually presents like a mild non-specific infection, but it may be responsible for fetal loss, preterm labor, early onset neonatal sepsis, and neonatal death. We report the case of a late stillbirth secondary to maternal chorioamnionitis. Listeria monocytogenes was isolated from the amniotic fluid and the fetal pleural fluid...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775325/fatal-disseminated-herpes-simplex-in-a-very-premature-neonate
#10
Ranjit I Kylat, Joel Addams, Richard E Sobonya
Herpes Simplex Virus infections (HSV) are ubiquitous. The neonatal HSV infection (NHSV) is rare. The incidence is estimated globally at only 10.3 per 100,000 births, but it can cause devastating disease in premature infants. Both HSV-1 and HSV-2 can be the etiologic agents in this type of vertically transmittted NHSV infection. Here we describe the pathological findings from a complete autopsy of a very low birth weight infant who succumbed to the infection despite early institution of antiviral treatment. We urge more awareness of this disease with continued surveillance; every effort should be taken to make an early diagnosis and thus prevent this devastating disease...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775324/dihydropyrimidine-dehydrogenase-deficiency-as-a-cause-of-fatal-5-fluorouracil-toxicity
#11
Shiraz S Fidai, Aarti E Sharma, Daniel N Johnson, Jeremy P Segal, Ricardo R Lastra
5-Fluorouracil (5-FU), in combination with other cytotoxic drugs, is commonly used to treat a variety of cancers. Dihydropyrimidine dehydrogenase (DPD) catalyzes the first catabolic step of the 5-FU degradation pathway, converting 80% of 5-FU to its inactive metabolite. Approximately 0.3% of the population demonstrate complete DPD deficiency, translating to extreme toxicity of 5-FU. Here we present a case of a patient who had a fatal outcome after treatment with 5-FU who was found to have an unknown DPD deficiency discovered at autopsy...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775323/multiple-hepatic-metastases-of-cardiac-angiosarcoma
#12
Marlone Cunha-Silva, Daniel Ferraz de Campos Mazo, Igor Logetto Caetité Gomes, Marcello Rabello Imbrizi, Tiago Sevá-Pereira, Nayana Fonseca Vaz, Mariana Sandoval Lourenço, Larissa Bastos Eloy da Costa, Cecilia Amelia Fazzio Escanhoela, Jazon Romilson de Souza Almeida
The differential diagnosis of hepatic focal lesions is challenging because the etiology can be inflammatory, infectious, and even neoplastic. A rare cause of metastatic liver nodules is cardiac angiosarcoma. We report a case of this tumor, which was diagnosed only after autopsy. A 26-year-old Caucasian man was admitted for progressive dyspnea and cough over the past 3 weeks. Physical examination showed only hypophonetic heart sounds. Laboratory analysis demonstrated anemia and elevated inflammatory markers, despite normal biochemical parameters and liver function...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775322/large-desmoid-tumors-in-familial-adenomatous-polyposis-a-successful-outcome
#13
Vítor Devezas, Laura Elisabete Barbosa, Rosa Ramalho, Cristina Sarmento, José Costa Maia
Desmoid tumors develop from connective tissue, fasciae, and aponeuroses, and may occur in the context of familial adenomatous polyposis or may arise sporadically; also, they may be extra-abdominal, intra-abdominal, or located in the abdominal wall. These benign tumors have a great aggressiveness with a high rate of local recurrence. Familial adenomatous polyposis is an inherited condition with autosomal dominant transmission, and is characterized by the development of multiple colonic and rectal adenomatous polyps, as well as desmoid tumors...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775321/oral-focal-mucinosis-of-the-hard-palate-and-gingiva
#14
Priscila Lie Tobouti, Fernando Kendi Horikawa, Bruno Fernandes Matuck, Suzana Cantanhede Orsini Machado de Sousa, Fábio Abreu Alves
Oral focal mucinosis (OFM) is an uncommon, asymptomatic, submucosal, slow-growing nodule representing a counterpart of the cutaneous focal mucinosis (CFM). OFM has a female predilection with the highest prevalence in the fifth decade of life. About 68% of OFMs occur in the gingiva and 14% in the palate. We present the case of a 41-year-old woman presenting a progressively growing mass on the palate, since the last 8 months. The diagnostic workup led to the diagnosis of an unusual OFM with the clinical presentation involving the gingiva and hard palate...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775320/malignant-ameloblastoma-a-challenging-diagnosis
#15
Ayodeji Salami, Uchenna Ezenkwa, Mudashiru Salami, Mustapha Ajani, Clement Okolo
Ameloblastoma is an uncommon and locally aggressive, benign, odontogenic tumor, with local recurrence when not adequately excised. A rare variant of this neoplasm with the benign features but accompanied with metastases has been described. This rare variant is malignant ameloblastoma and is known to have a poor prognosis. We present the case of a young woman who had recurrent mandibular tumors, which were resected twice and histologically reported as ameloblastoma. Four years later, she presented with pulmonary metastasis and atelectasis...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775319/primary-endometrial-large-cell-neuroendocrine-carcinoma-with-melanocytic-differentiation
#16
Lucinda Calheiros Guimarães, Priscila Leandro Garcia, João Badaró Castro, Antonio Carlos Oliveira Meneses
High-grade endometrial carcinomas are aggressive neoplasms of difficult histological classification. Neuroendocrine differentiation in endometrial carcinomas is rare. This is the report of an endometrial large cell neuroendocrine carcinoma with foci of melanocytic differentiation in a 75-year-old woman with abnormal post-menopausal uterine bleeding for 2 years. Two initial biopsies were inconclusive. Histopathological examination of the uterus revealed large cell neuroendocrine carcinoma associated with endometrioid carcinoma and foci of melanocytic differentiation, pT3a (FIGO IIIA)...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30775318/fibrosarcomatous-dermatofibrosarcoma-protuberans-from-scar-following-trauma
#17
Sang Wook Lee, Araya Zaesim, Amanda Jackson, Michael Borkat
Dermatofibrosarcoma protuberans (DFSP) is an uncommon soft tissue neoplasm of low metastatic potential notable for its progressive growth and high rate of local recurrence after surgical excision. Fibrosarcomatous transformation of DFSP (FS-DFSP) is a rare variant characterized by higher rates of local recurrence and metastasis. Trauma has been hypothesized as a potential risk factor for the development of DFSP, although clear evidence has been lacking. In this study, we report a case of FS-DFSP that was found arising from a previously stable scar following a traumatic injury...
October 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30237990/autopsy-in-the-elderly
#18
EDITORIAL
Luiz Eugênio Garcez Leme
No abstract text is available yet for this article.
July 2018: Autopsy & Case Reports
https://read.qxmd.com/read/30237989/odontogenic-myxoma-in-a-child-treated-with-enucleation-and-curettage
#19
Samanta Vicente Oliveira, Andre Caroli Rocha, Marcelo Minharro Ceccheti, Camila de Barros Gallo, Fábio Abreu Alves
Odontogenic myxoma is an aggressive benign odontogenic tumor, accounting for 3-6% of all the odontogenic tumors in adults. The incidence among children is lower. Due to its clinical behavior, there is no consensus on the best treatment. In this paper, the authors report the case of a 9-year-old girl with the diagnosis of odontogenic myxoma. The panoramic X-ray showed an extensive radiolucent lesion involving the left mandibular body causing teeth displacement. The treatment consisted of tumor enucleation followed by vigorous curettage of the bone walls...
July 2018: Autopsy & case reports
https://read.qxmd.com/read/30237988/the-lethal-twist-a-story-of-unspoken-pain-small-intestinal-volvulus-in-cerebral-palsy
#20
Kritika Krishnamurthy, Siba El Hussein, Yumna Omarzai
Small intestinal volvulus (SBV) is the abnormal twisting of bowel around the axis of its mesentery, leading to obstruction and vascular compromise, resulting in bowel ischemia and necrosis which are life-threatening. Risk factors include malformation, malrotation, and adhesions. Its rare incidence and vague clinical presentation make it a difficult diagnosis, more so in a nonverbal patient who cannot express his pain, which is the first and most prominent symptom. Studies suggest an increased frequency of intestinal obstruction in cerebral palsy patients...
July 2018: Autopsy & case reports
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