journal
https://read.qxmd.com/read/38213877/necrotizing-fasciitis-and-fatal-septic-shock-associated-with-streptococcus-constellatus
#1
Fareed Rajack, Shawn Medford, Tammey Naab
Streptococcus constellatus is usually a benign, commensal bacteria but has increased incidence in blood cultures and abscesses. This pathogenic involvement is most prevalent in individuals with underlying medical conditions, such as solid tumors and type 2 diabetes mellitus, as well as in cases of community-acquired infections. We report a 43-year-old male with a right medial thigh ulcer and necrotic scrotal skin. The wound culture from surgical debridement grew Streptococcus constellatus, and histology was consistent with stage III necrotizing fasciitis...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38213876/spongiform-leukoencephalopathy-unveiled-in-an-autopsy-of-a-drug-abuser
#2
Hemlata Jangir, Govinda Balmuchu, Jhansi Lakshmi Mylapalli, Arulselvi Subramanian, Sanjeev Lalwani
Toxic leukoencephalopathy (TLE) is a rare neurological debilitating and fatal condition. It has been previously associated with exposure to leukotoxic offenders such as chemotherapy, cranial radiation, certain drugs, and environmental factors. Currently, it is a commoner white matter syndrome resulting from increased substance abuse, classically by inhaled heroin and other opioids. Herein, we report a case of fatal TLE unveiled in an autopsy of a drug abuser. A 24-year-old male was found dead on the roadside...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38213875/chondroblastic-osteosarcoma
#3
JOURNAL ARTICLE
Neha Bhardwaj, Vikas Bachhal, Uma Nahar Saikia
No abstract text is available yet for this article.
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38149072/ovarian-hydatid-cyst-an-uncommon-site-of-presentation
#4
Kaushlendra Kumar, Ariba Zaidi, Nuzhat Husain
Hydatid cyst is a parasitic infestation caused by Echinococcus larvae. Hydatid cyst of the ovary is a highly unusual presentation. Herein, we present a case of a young woman who complained of episodic lower abdominal pain. Ultrasound of the abdomen revealed a multi-cystic left adnexal mass measuring 86 mm x 67 mm. A possibility of ovarian cystic neoplasm was suggested. Unilateral salpingo-oophorectomy was performed. On histopathological examination, a cyst measuring 8.0 x 5.5 x 4.5 cm was found, replacing the entire ovary...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38149071/epididymal-adrenal-rest-in-an-orchiectomy-specimen-with-seminoma
#5
JOURNAL ARTICLE
Luca Ventura, Giulia Del Rosario, Martina Di Franco, Veronica Forte, Massimo Menichini, Guido Ranieri
No abstract text is available yet for this article.
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38149070/inclusion-body-fibromatosis
#6
JOURNAL ARTICLE
Elgiva Iangngap, Mayur Parkhi, Aravind Sekar, Parmod Kumar, Uma Nahar Saikia
No abstract text is available yet for this article.
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38149069/rosai-dorfman-disease-of-the-oral-cavity
#7
Abir Charfeddine, Mounir Omami, Marwa Garma, Ahlem Bellalah, Sameh Sioud, Jamil Selmi
First described by J Rosai and R F Dorfman in 1969, Rosai-Dorfman disease (RDD) is a benign, self-limiting histiocytosis of unknown etiology. It is usually seen in the first two decades of life. The most frequent clinical presentation is painless, bilateral cervical lymphadenopathy accompanied by fever, weight loss, and an elevated ESR. However, RDD without nodal involvement is extremely rare, and the most common extranodal location is the head and neck region, mainly affecting the nasal cavity, pharynx, and paranasal sinuses...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38149068/anorectal-balloon-cell-melanoma-a-rare-variant
#8
Priyanka Sameer, Pallavi Srivastava, Saumya Shukla, Nuzhat Husain
Balloon cell melanoma is a rare presentation of malignant melanoma, usually on the skin, with less than 100 cases reported. Mucosal BCM is even rarer, with only one case of anorectal BCM reported in English literature. The diagnosis is based on the histopathologic findings of a tumor composed of large, foamy melanocytes, with or without pigmentation, and confirmed by immunohistochemical studies showing expression for melanocytic markers. The foam cell appearance of the tumor cells and the lack of melanin pigment lead to a diagnostic dilemma, mostly when presented at an unusual location...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38046944/dermal-cylindroma-of-the-external-auditory-canal
#9
Vivek Dokania, Indranil Mukherjee
External auditory canal (EAC) cylindroma is a rare tumor that mainly presents as a painless mass over the lateral aspect of the ear canal. They have been designated under different nomenclatures in the literature, and controversies persist about their etiology and histogenesis. Moreover, a clinical diagnosis of EAC cylindroma is often challenging because of their rarity and a close resemblance with other adnexal benign and malignant tumors. None of the previous authors have extensively reviewed the dermal cylindroma of the EAC...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38034525/disseminated-nasal-subtype-extranodal-nk-t-cell-lymphoma-and-its-diagnostic-difficulties-in-antemortem-biopsies
#10
Aravind Sekar, Siddharth Jain, Jaimanti Bakshi, Suneel Rachagiri, Harish Bhujade, Rajender Kumar, Amanjit Bal
Extranodal NK/T- cell lymphoma (ENKTCL) is an aggressive lymphoma driven by Epstein-Barr virus (EBV) infection in genetically susceptible individuals. It was historically called a lethal midline granuloma. Due to the angio-destructive nature of ENKTCL, lymphoma cells are often accompanied and masked by necrosis and dense inflammation in the biopsy. Further, the biopsy may show vasculitis, which can mimic granulomatosis with polyangiitis. Due to these masquerades, ENKTCL is often misdiagnosed in the biopsy. Several biopsies may be required to establish the diagnosis...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38034524/biliary-adenofibroma-a-precursor-lesion-of-intrahepatic-cholangiocarcinoma
#11
Mayur Parkhi, Rashmi Joshi, Manish Kumar, Aditi Sharma, Suvradeep Mitra, Lileswar Kaman
Biliary adenofibroma (BAF) is an uncommon liver tumor with a high propensity for malignant transformation. The histomorphology of BAF with malignant transformation can show a spectrum of changes ranging from benign, dysplastic to frank malignancy. Thus, the diagnosis of BAF imposes the pursuit of dysplasia/ malignancy focus. We presented a case of intrahepatic cholangiocarcinoma arising from BAF in a 49-year-old woman with detailed histomorphology. We also performed a PubMed database search and tabulated all previously reported cases of BAF with dysplasia/ malignant transformation...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38034523/alcoholic-foamy-degeneration-an-unusual-presentation-of-the-alcoholic-liver-disease-diagnosed-on-autopsy
#12
Rashmi Joshi, Mayur Parkhi, Anjali Gupta, Terence Susngi, Ashwani Kumar, Deba Prasad Dhibar, Suvradeep Mitra
Alcoholic foamy degeneration (AFD) is an uncommon presentation of alcoholic liver disease (ALD) with characteristic histologic findings of foamy-looking hepatocytes due to the presence of abundant microvesicles of fat within the cytoplasm predominantly in perivenular and midzonal regions without inflammation and fibrosis. It is underdiagnosed as the patients quickly recover after alcoholic abstinence and are rarely caught on biopsies. AFD has better prognosis than alcoholic hepatitis, and the injury mechanism is different, warranting a different diagnosis...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38034522/gingival-cyst-of-the-adult
#13
Maria Emília Mota, Dandara Menezes de Araujo Oliveira, Yuri de Lima Medeiros, Maria Stella Moreira, Rodrigo Nascimento Lopes, Fábio Abreu Alves, Brendo Vinícius Rodrigues Louredo, Pablo Agustin Vargas, José Divaldo Prado
The gingival cyst of the adult (GCA) is a rare odontogenic cyst, consisting of 0.3% of all odontogenic cysts. This case report, based on CARE guidelines for case reports, aims to present a case of a 52-year-old female patient with a symptomatic translucent nodule in the upper left anterior gingiva, measuring approximately 6mm. Excisional biopsy was performed, and the histological examination revealed multiple cystic cavities lined by the squamous epithelium of varying thickness with focal areas of nodular thickenings...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38034521/gallbladder-adenocarcinoma-skin-metastasis
#14
JOURNAL ARTICLE
Arvind Kumar, Tushar Kalonia, Akanksha Gupta, Ravi Hari Phulware
No abstract text is available yet for this article.
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38034520/rare-association-between-giant-cell-aortitis-and-giant-cell-aortic-valvulitis
#15
Georgina Del Cisne Jadán Luzuriaga, Ricardo Ribeiro Dias, José Augusto Duncan Santiago, Vagner Madrini, Walther Yoshiharu Ishikawa, Fabio Fernandes, Vera Demarchi Aiello
Giant cell arteritis (GCA) is a type of chronic vasculitis that affects medium and large-caliber arteries, frequently related to aortic involvement and, consequently, to aneurysm formation. However, associated valvulitis with giant cells is uncommon. We describe the case of a 50-year-old female patient with aortic aneurysm and valvular insufficiency, whose anatomopathological examination revealed giant-cell aortic valvulitis associated with giant cell aortitis.
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38034519/small-cell-neuroendocrine-carcinoma-with-adenocarcinoma-and-high-grade-squamous-intraepithelial-neoplasia-of-the-cervix
#16
Guralarasan Gurubalan, Amber Parwaiz, Surabhi Ajit, Tarun Kumar, Madhu Kumari, Punam Bhadani
Neuroendocrine neoplasm (NEN) of the cervix is a malignant tumor and is classified into low and intermediate-grade neuroendocrine tumor (NET), and high-grade small cell neuroendocrine carcinoma (SCNEC), and large cells neuroendocrine carcinoma (LCNEC). SCNEC of the cervix is an Infrequent tumor with an incidence of less than 1% of all gynecological malignancies. It is characterized by small to medium-sized tumor cells with scant cytoplasm and neuroendocrine differentiation. Most cases of SCNEC of the cervix manifest in pure forms, and only cases show coexisting, non-neuroendocrine component of HPV-associated adenocarcinoma or squamous cell carcinoma...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38034518/bilateral-virchow-nodes-an-unusual-finding-of-pulmonary-small-cell-neuroendocrine-carcinoma-metastasis
#17
Matthew J Zdilla, Alexander R Gross, Tara Hajarat, Jeffrey A Vos
An enlarged left-sided supraclavicular node is a signal node for cancer metastasis. In such a case, the enlarged lymph node is often referred to as a Virchow node. The left-sided nature of the node is due to the drainage of the thoracic duct. So, the enlargement of a Virchow node is typically associated with malignancies, including gastrointestinal, pulmonary, and genitourinary carcinomas, in addition to lymphomas. This report documents a particularly unusual finding: bilateral Virchow nodes, representing metastasis of small-cell neuroendocrine carcinoma...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38034517/acantholytic-oral-squamous-cell-carcinoma-with-clear-cell-change-a-rare-amalgamated-variant
#18
Gitika Sharma, Anju Devi, Mala Kamboj, Anjali Narwal
BACKGROUND: Acantholytic squamous cell carcinoma (ASCC) is an uncommon histological variation of oral squamous cell carcinoma (OSCC), accounting for fewer than 4% of all occurrences. The tumor shows a slight masculine predisposition, with the lower lip being the most commonly affected location. ASCC is reported to have a diverse biologic behavior, which explains its ability to metastasize to distant places and, thus, its poor prognosis. Similarly, clear cell change in OSCC is a rare occurrence with an unknown etiology that suggests its aggressive nature...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38034516/radiologic-pathologic-autopsy-correlation-of-an-internal-watershed-infarct-a-case-report
#19
Thomas Dimitrios Zaikos, David M Yousem, Juan C Troncoso, James Stephen Nix
Internal watershed infarcts (IWIs) occur at the junction of the deep and superficial perforating arterial branches of the cerebrum. Despite documentation in the radiology literature, IWIs are rarely encountered at the time of autopsy. Here, we report the case of a 59-year-old incarcerated male who was brought to the emergency department after being found unresponsive on the floor of his jail cell. Initial examination and imaging demonstrated right-sided hemiplegia, aphasia, right facial droop, and severe stenosis of the left middle cerebral artery, respectively...
2023: Autopsy & Case Reports
https://read.qxmd.com/read/38034515/-clostridioides-difficile-infection-leading-to-fulminant-colitis-with-toxic-megacolon
#20
Fareed Rajack, Shawn Medford, Tammey Naab
Clostridioidesdifficile infection (CDI) is the culprit of millions of nosocomial infections in the United States. Programs that successfully decrease its incidence, therefore, render cost savings for the healthcare system. Toxic megacolon and perforation are two of the most significant complications with increased mortality rates. We report a 23-year-old nursing home resident hospitalized for fever, cough, and green sputum. After 3 days of antibiotic therapy, he developed abdominal distension, diarrhea, and vomiting and underwent a total colectomy...
2023: Autopsy & Case Reports
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