journal
https://read.qxmd.com/read/38611694/opportunistic-screening-for-acute-vertebral-fractures-on-a-routine-abdominal-or-chest-computed-tomography-scans-using-an-automated-deep-learning-model
#1
JOURNAL ARTICLE
Ye Rin Kim, Yu Sung Yoon, Jang Gyu Cha
OBJECTIVES: To develop an opportunistic screening model based on a deep learning algorithm to detect recent vertebral fractures in abdominal or chest CTs. MATERIALS AND METHODS: A total of 1309 coronal reformatted images (504 with a recent fracture from 119 patients, and 805 without fracture from 115 patients), from torso CTs, performed from September 2018 to April 2022, on patients who also had a spine MRI within two months, were included. Two readers participated in image selection and manually labeled the fractured segment on each selected image with Neuro-T (version 2...
April 8, 2024: Diagnostics
https://read.qxmd.com/read/38611693/specificities-in-the-structure-of-the-cartilage-of-patients-with-advanced-stages-of-developmental-dysplasia-of-the-hip
#2
JOURNAL ARTICLE
Tea Duvančić, Andreja Vukasović Barišić, Ana Čizmić, Mihovil Plečko, Ivan Bohaček, Domagoj Delimar
Developmental dysplasia of the hip (DDH) presents varying degrees of femoral head dislocation, with severe cases leading to the formation of a new articular surface on the external side of the iliac bone-the neoacetabulum. Despite conventional understanding suggesting otherwise, a tissue resembling hyaline cartilage is found in the neoacetabulum and acetabulum of Crowe III and IV patients, indicating a potential for hyaline cartilage development without mechanical pressure. To test this theory, acetabular and femoral head cartilage obtained from patients with DDH was stained with hematoxylin-eosin and toluidine blue...
April 8, 2024: Diagnostics
https://read.qxmd.com/read/38611692/the-doppler-perfusion-index-of-the-liver-and-the-underlying-duplex-sonography-of-visceral-vessels-a-systematic-and-comprehensive-evaluation-of-reproducibility
#3
JOURNAL ARTICLE
Christian Lueders, Johannes Gladitz, Georg Bauer, Christian Jenssen, Jana Belaschki, Arndt von Kirchbach, Christoph Schneider, Thomas Kiefer, Heinz Voeller, Daniel Merkel
Prior to the curative resection of colorectal carcinoma (CRC) or pancreatic ductal adenocarcinoma (PDAC), the exclusion of hepatic metastasis using cross-sectional imaging is mandatory. The Doppler perfusion index (DPI) of the liver is a promising method for detecting occult liver metastases, but the underlying visceral duplex sonography is critically viewed in terms of its reproducibility. The aim of this study was to investigate systematically the reproducibility of the measured variables, the calculated blood flow, and the DPI...
April 8, 2024: Diagnostics
https://read.qxmd.com/read/38611691/tumid-lupus-erythematosus-tle-a-review-of-a-rare-variant-of-chronic-cutaneous-lupus-erythematosus-ccle-with-emphasis-on-differential-diagnosis
#4
REVIEW
Maged Daruish, Francesca Ambrogio, Caterina Foti, Alessandra Filosa, Gerardo Cazzato
Tumid lupus erythematosus (TLE) has been the subject of heated debate regarding its correct nosographic classification. The definition of TLE has changed over time, varying according to the different studies performed. In this review, we address the initial definition of TLE, the changes that have taken place in the understanding of TLE, and its placement within the classification of cutaneous lupus erythematosus (CLE), with a focus on clinical, histopathological, immunophenotypical, and differential diagnosis aspects...
April 8, 2024: Diagnostics
https://read.qxmd.com/read/38611690/the-diagnostic-value-of-soluble-triggering-receptor-expressed-on-myeloid-cells-for-patients-with-acute-stone-pyelonephritis
#5
JOURNAL ARTICLE
Metin Özsoy, Miraç Ataman, Serhat Kazım Şahin, İbrahim Şenocak, Artuner Varlibaş, Ercan Yuvanç, Aydın Çifci, Mustafa Kemal Başaralı, Gül Kırtıl, Erdal Yilmaz
Soluble triggering receptor expressed on myeloid cells (sTREM-1) is a new biomarker that can be used for the diagnosis and monitoring of urinary system infections. This study aimed to evaluate the diagnostic performance of serum sTREM-1 in patients with a diagnosis of acute stone pyelonephritis (ASP). This prospective study included 46 patients with a diagnosis of ASP and a control group of 23 individuals without urinary system infection. Blood samples were taken from participants upon hospital admission, and basal serum sTREM-1 levels were analyzed using the ELISA method...
April 7, 2024: Diagnostics
https://read.qxmd.com/read/38611689/the-clinical-impact-of-the-pulmonary-embolism-severity-index-on-the-length-of-hospital-stay-of-patients-with-pulmonary-embolism-a-randomized-controlled-trial
#6
JOURNAL ARTICLE
Marco Paolo Donadini, Nicola Mumoli, Patrizia Fenu, Fulvio Pomero, Roberta Re, Gerardo Palmiero, Laura Spadafora, Valeria Mazzi, Alessandra Grittini, Lorenza Bertù, Drahomir Aujesky, Francesco Dentali, Walter Ageno, Alessandro Squizzato
BACKGROUND: The Pulmonary Embolism Severity Index (PESI) is an extensively validated prognostic score, but impact analyses of the PESI on management strategies, outcomes and health care costs are lacking. Our aim was to assess whether the adoption of the PESI for patients admitted to an internal medicine ward has the potential to safely reduce the length of hospital stay (LOS). METHODS: We carried out a multicenter randomized controlled trial, enrolling consecutive adult outpatients diagnosed with acute PE and admitted to an internal medicine ward...
April 7, 2024: Diagnostics
https://read.qxmd.com/read/38611688/utility-of-dual-energy-computed-tomography-in-clinical-conundra
#7
REVIEW
Ahmad Abu-Omar, Nicolas Murray, Ismail T Ali, Faisal Khosa, Sarah Barrett, Adnan Sheikh, Savvas Nicolaou, Stefania Tamburrini, Francesca Iacobellis, Giacomo Sica, Vincenza Granata, Luca Saba, Salvatore Masala, Mariano Scaglione
Advancing medical technology revolutionizes our ability to diagnose various disease processes. Conventional Single-Energy Computed Tomography (SECT) has multiple inherent limitations for providing definite diagnoses in certain clinical contexts. Dual-Energy Computed Tomography (DECT) has been in use since 2006 and has constantly evolved providing various applications to assist radiologists in reaching certain diagnoses SECT is rather unable to identify. DECT may also complement the role of SECT by supporting radiologists to confidently make diagnoses in certain clinically challenging scenarios...
April 7, 2024: Diagnostics
https://read.qxmd.com/read/38611687/a-diagnostic-driven-prospective-clinical-study-evaluating-the-combination-of-an-antibiofilm-agent-and-negative-pressure-wound-therapy
#8
JOURNAL ARTICLE
Thomas E Serena, Emily King, Laura Serena, Kristy Breisinger, Omar Al-Jalodi, Matthew F Myntti
BACKGROUND: Each year, millions of Americans develop truncal pressure ulcers (PUs) which can persist for months, years, or until the end of life. Despite the negative impact on quality of life and escalating costs associated with PUs, there is sparse evidence supporting validated and efficacious treatment options. As a result, treatment is based on opinion and extrapolation from other wound etiologies. The ideal reconstructive plan maximizes the patient's nutritional status, incorporates the basic tenets of wound bed preparation (debridement, offloading, proper moisture balance, reduction of bacterial burden), and employs diagnostics to guide therapeutic intervention...
April 7, 2024: Diagnostics
https://read.qxmd.com/read/38611686/artificial-intelligence-in-medical-imaging-analyzing-the-performance-of-chatgpt-and-microsoft-bing-in-scoliosis-detection-and-cobb-angle-assessment
#9
JOURNAL ARTICLE
Artur Fabijan, Agnieszka Zawadzka-Fabijan, Robert Fabijan, Krzysztof Zakrzewski, Emilia Nowosławska, Bartosz Polis
Open-source artificial intelligence models (OSAIM) find free applications in various industries, including information technology and medicine. Their clinical potential, especially in supporting diagnosis and therapy, is the subject of increasingly intensive research. Due to the growing interest in artificial intelligence (AI) for diagnostic purposes, we conducted a study evaluating the capabilities of AI models, including ChatGPT and Microsoft Bing, in the diagnosis of single-curve scoliosis based on posturographic radiological images...
April 5, 2024: Diagnostics
https://read.qxmd.com/read/38611685/imaging-considerations-before-and-after-liver-directed-locoregional-treatments-for-metastatic-colorectal-cancer
#10
REVIEW
David-Dimitris Chlorogiannis, Amgad M Moussa, Ken Zhao, Erica S Alexander, Constantinos T Sofocleous, Vlasios S Sotirchos
Colorectal cancer is a leading cause of cancer-related death. Liver metastases will develop in over one-third of patients with colorectal cancer and are a major cause of morbidity and mortality. Even though surgical resection has been considered the mainstay of treatment, only approximately 20% of the patients are surgical candidates. Liver-directed locoregional therapies such as thermal ablation, Yttrium-90 transarterial radioembolization, and stereotactic body radiation therapy are pivotal in managing colorectal liver metastatic disease...
April 5, 2024: Diagnostics
https://read.qxmd.com/read/38611684/association-of-genetic-risk-for-age-related-macular-degeneration-with-morphological-features-of-the-retinal-microvascular-network
#11
JOURNAL ARTICLE
Adam Sendecki, Daniel Ledwoń, Aleksandra Tuszy, Julia Nycz, Anna Wąsowska, Anna Boguszewska-Chachulska, Adam Wylęgała, Andrzej W Mitas, Edward Wylęgała, Sławomir Teper
BACKGROUND: Age-related macular degeneration (AMD) is a multifactorial disease encompassing a complex interaction between aging, environmental risk factors, and genetic susceptibility. The study aimed to determine whether there is a relationship between the polygenic risk score (PRS) in patients with AMD and the characteristics of the retinal vascular network visualized by optical coherence tomography angiography (OCTA). METHODS: 235 patients with AMD and 97 healthy controls were included...
April 5, 2024: Diagnostics
https://read.qxmd.com/read/38611683/ambulatory-risk-stratification-for-worsening-heart-failure-in-patients-with-reduced-and-preserved-ejection-fraction-using-diagnostic-parameters-available-in-implantable-cardiac-monitors
#12
JOURNAL ARTICLE
Shantanu Sarkar, Jodi Koehler, Neethu Vasudevan
BACKGROUND: Ambulatory risk stratification for worsening heart failure (HF) using diagnostics measured by insertable cardiac monitors (ICM) may depend on the left ventricular ejection fraction (LVEF). We evaluated risk stratification performance in patients with reduced versus preserved LVEF. METHODS: ICM patients with a history of HF events (HFEs) were included from the Optum® de-identified Electronic Health Record dataset merged with ICM device-collected data during 2007-2021...
April 5, 2024: Diagnostics
https://read.qxmd.com/read/38611682/comprehensive-oral-diagnosis-and-management-for-women-with-turner-syndrome
#13
JOURNAL ARTICLE
Victoria Tallón-Walton, Meritxell Sánchez-Molins, Wenwen Hu, Neus Martínez-Abadías, Aroa Casado, María Cristina Manzanares-Céspedes
Turner Syndrome (TS) is a rare genetic disorder that affects females when one of the X chromosomes is partially or completely missing. Due to high genetic and phenotypic variability, TS diagnosis is challenging and is often delayed until adolescence, resulting in poor clinical management. Numerous oral, dental and craniofacial anomalies have been associated with TS, yet a comprehensive description is still lacking. This study addresses this gap through a detailed analysis of oral health and craniofacial characteristics in a cohort of 15 females with TS and their first-degree relatives...
April 5, 2024: Diagnostics
https://read.qxmd.com/read/38611681/comparison-between-two-adaptive-optics-methods-for-imaging-of-individual-retinal-pigmented-epithelial-cells
#14
JOURNAL ARTICLE
Elena Gofas-Salas, Daniel M W Lee, Christophe Rondeau, Kate Grieve, Ethan A Rossi, Michel Paques, Kiyoko Gocho
The Retinal Pigment Epithelium (RPE) plays a prominent role in diseases such as age-related macular degeneration, but imaging individual RPE cells is challenging due to their high absorption and low autofluorescence emission. The RPE lies beneath the highly reflective photoreceptor layer (PR) and contains absorptive pigments, preventing direct backscattered light detection when the PR layer is intact. Here, we used near-infrared autofluorescence adaptive optics scanning laser ophthalmoscopy (NIRAF AOSLO) and transscleral flood imaging (TFI) in the same healthy eyes to cross-validate these approaches...
April 4, 2024: Diagnostics
https://read.qxmd.com/read/38611680/artificial-intelligence-based-left-ventricular-ejection-fraction-by-medical-students-for-mortality-and-readmission-prediction
#15
JOURNAL ARTICLE
Ziv Dadon, Moshe Rav Acha, Amir Orlev, Shemy Carasso, Michael Glikson, Shmuel Gottlieb, Evan Avraham Alpert
INTRODUCTION: Point-of-care ultrasound has become a universal practice, employed by physicians across various disciplines, contributing to diagnostic processes and decision-making. AIM: To assess the association of reduced (<50%) left-ventricular ejection fraction (LVEF) based on prospective point-of-care ultrasound operated by medical students using an artificial intelligence (AI) tool and 1-year primary composite outcome, including mortality and readmission for cardiovascular-related causes...
April 4, 2024: Diagnostics
https://read.qxmd.com/read/38611679/comparative-analysis-of-examination-methods-for-periapical-lesion-diagnostics-assessing-cone-beam-computer-tomography-ultrasound-and-periapical-radiography
#16
JOURNAL ARTICLE
Aleksandra Karkle, Anda Slaidina, Maksims Zolovs, Anete Vaskevica, Dita Meistere, Zanda Bokvalde, Laura Neimane
INTRODUCTION: Periapical lesions of teeth are typically evaluated using periapical X-rays (PA) or cone-beam computer tomography (CBCT); however, ultrasound imaging (US) can also be used to detect bone defects. A comparative analysis is necessary to establish the diagnostic accuracy of US for the detection of periapical lesions in comparison with PA and CBCT. OBJECTIVES: This study aimed to evaluate and compare the measurement precision of US against PA and CBCT in detecting periapical lesions...
April 4, 2024: Diagnostics
https://read.qxmd.com/read/38611678/occult-breast-cancer-presenting-as-sternum-pain
#17
JOURNAL ARTICLE
Dang Wu, Siyu Guo, Bicheng Zhang, Fengbo Huang, Wei Qian, Fuming Qiu, Qichun Wei, Ting Zhang
Bone metastasis has been reported in up to 70% of patients with advanced breast cancer. A total of 55.76% of skeletal metastases in women were derived from breast cancer. However, patients with bone metastasis from an occult primary breast cancer are a rare subset of patients. Here, we present the case of a 38-year-old woman who had sternum pain for 4 months. A whole-body PET-CT scan revealed that the FDG uptake of both the sternum and internal mammary node was significantly increased. The final diagnosis of occult breast cancer was established by immunohistochemical (IHC) staining, which is of great significance for identifying the origin of a metastatic tumor despite no visualized lesions of mammary glands...
April 4, 2024: Diagnostics
https://read.qxmd.com/read/38611677/non-neovascular-age-related-macular-degeneration-assessment-focus-on-optical-coherence-tomography-biomarkers
#18
REVIEW
Daniela Adriana Iliescu, Ana Cristina Ghita, Larisa Adriana Ilie, Suzana Elena Voiculescu, Aida Geamanu, Aurelian Mihai Ghita
The imagistic evaluation of non-neovascular age-related macular degeneration (AMD) is crucial for diagnosis, monitoring progression, and guiding management of the disease. Dry AMD, characterized primarily by the presence of drusen and retinal pigment epithelium atrophy, requires detailed visualization of the retinal structure to assess its severity and progression. Several imaging modalities are pivotal in the evaluation of non-neovascular AMD, including optical coherence tomography, fundus autofluorescence, or color fundus photography...
April 3, 2024: Diagnostics
https://read.qxmd.com/read/38611676/diagnosing-cystic-fibrosis-in-the-21st-century-a-complex-and-challenging-task
#19
REVIEW
Dana-Teodora Anton-Păduraru, Alice Nicoleta Azoicăi, Felicia Trofin, Dana Elena Mîndru, Alina Mariela Murgu, Ana Simona Bocec, Codruța Olimpiada Iliescu Halițchi, Carmen Iulia Ciongradi, Ioan Sȃrbu, Maria Liliana Iliescu
Cystic fibrosis (CF) is a chronic and potentially life-threatening condition, wherein timely diagnosis assumes paramount significance for the prompt initiation of therapeutic interventions, thereby ameliorating pulmonary function, addressing nutritional deficits, averting complications, mitigating morbidity, and ultimately enhancing the quality of life and extending longevity. This review aims to amalgamate existing knowledge to provide a comprehensive appraisal of contemporary diagnostic modalities pertinent to CF in the 21st century...
April 3, 2024: Diagnostics
https://read.qxmd.com/read/38611675/diagnostic-accuracy-of-the-triglyceride-glucose-index-tyg-tyg-body-mass-index-and-tyg-waist-circumference-index-for-liver-steatosis-detection
#20
JOURNAL ARTICLE
Alejandra Mijangos-Trejo, Raúl Gómez-Mendoza, Martha Helena Ramos-Ostos, Graciela Castro-Narro, Misael Uribe, Eva Juárez-Hernández, Iván López-Méndez
BACKGROUND: The triglyceride-glucose index (TyG) and a combination of body mass index (BMI) and waist circumference (WC) have been proposed as predictive scores for liver steatosis (LS). The aim of this study was to determine the diagnostic accuracy of these indices compared with controlled attenuation parameters (CAPs) and other predictive scores of LS. METHODS: A retrospective analysis of patients who attended a check-up unit in 2021 was performed. LS was determined by CAP...
April 3, 2024: Diagnostics
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