Nora Penzel, Rachele Sanfelici, Linda A Antonucci, Linda T Betz, Dominic Dwyer, Anne Ruef, Kang Ik K Cho, Paul Cumming, Oliver Pogarell, Oliver Howes, Peter Falkai, Rachel Upthegrove, Stefan Borgwardt, Paolo Brambilla, Rebekka Lencer, Eva Meisenzahl, Frauke Schultze-Lutter, Marlene Rosen, Theresa Lichtenstein, Lana Kambeitz-Ilankovic, Stephan Ruhrmann, Raimo K R Salokangas, Christos Pantelis, Stephen J Wood, Boris B Quednow, Giulio Pergola, Alessandro Bertolino, Nikolaos Koutsouleris, Joseph Kambeitz
Continued cannabis use (CCu) is an important predictor for poor long-term outcomes in psychosis and clinically high-risk patients, but no generalizable model has hitherto been tested for its ability to predict CCu in these vulnerable patient groups. In the current study, we investigated how structured clinical and cognitive assessments and structural magnetic resonance imaging (sMRI) contributed to the prediction of CCu in a group of 109 patients with recent-onset psychosis (ROP). We tested the generalizability of our predictors in 73 patients at clinical high-risk for psychosis (CHR)...
March 9, 2022: NPJ Schizophrenia