journal
MENU ▼
Read by QxMD icon Read
search

Journal of Virus Eradication

journal
https://read.qxmd.com/read/30800430/highlights-from-hiv-glasgow-28-31-october-2018-glasgow-uk
#1
EDITORIAL
Christina K Psomas, Patrick Philibert, Sabine Kinloch
No abstract text is available yet for this article.
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30800429/the-global-campaign-to-eliminate-hbv-and-hcv-infection-international-viral-hepatitis-elimination-meeting-and-core-indicators-for-development-towards-the-2030-elimination-goals
#2
EDITORIAL
Stephanie Popping, Debora Bade, Charles Boucher, Mark van der Valk, Manal El-Sayed, Olafsson Sigurour, Vana Sypsa, Timothy Morgan, Amiran Gamkrelidze, Constance Mukabatsinda, Sylvie Deuffic-Burban, Michael Ninburg, Jordan Feld, Margaret Hellard, John Ward
Hepatitis B virus (HBV) and hepatitis C virus (HCV) affect more than 320 million people worldwide, which is more than HIV, tuberculosis (TB) and malaria combined. Elimination of HBV and HCV will, therefore, produce substantial public health and economic benefits and, most importantly, the prevention of 1.2 million deaths per year. In 2016, member states of the World Health Assembly unanimously adopted a resolution declaring that viral hepatitis should be eliminated by 2030. Currently, few countries have elimination programmes in place and even though the tools to achieve elimination are available, the right resources, commitments and allocations are lacking...
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30800428/highlights-from-the-fourth-biennial-strategies-for-an-hiv-cure-meeting-10-12-october-2018-bethesda-md-usa
#3
EDITORIAL
Lillian Kuo, Diane Lawrence, David McDonald, Eric Refsland, Sandra Bridges, Stephen Smiley, Randall L Tressler, Candice Beaubien, Karl Salzwedel
The National Institute of Allergy and Infectious Diseases (NIAID) organised the Strategies for an HIV Cure 2018 meeting focused on research to develop innovative strategies for eradicating or achieving long-term remission of HIV infection. The purpose was to bring together researchers studying HIV persistence and cure strategies, including the six National Institutes of Health (NIH)-funded Martin Delaney Collaboratories for HIV Cure Research (MDCs), as well as industry and community partners, to share scientific results and stimulate active discussion among all stakeholders about the merits of various approaches under investigation...
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30800427/immunological-profile-of-an-infant-treated-with-integrase-inhibitor-from-the-neonatal-period
#4
EDITORIAL
Lucia Taramasso, Chiara Dentone, Paola Tatarelli, Bianca Bruzzone, Francesco Marras, Andrea De Maria, Cristina Gotta, Elio Castagnola, Gilberto Filaci, Claudio Viscoli, Daniela Fenoglio, Antonio Di Biagio
No abstract text is available yet for this article.
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30800426/case-series-of-infertility-amongst-young-women-with-perinatally-acquired-hiv-data-from-a-london-cohort
#5
EDITORIAL
Jhia Teh, Thomas Pasvol, Sara Ayres, Caroline Foster, Sarah Fidler
Introduction: Increased rates of infertility have been reported in women who acquired HIV horizontally compared to population age-matched normative data. However, few data exist for adults with perinatally acquired HIV (PaHIV), who have been exposed to antiretroviral drugs and/or HIV-associated ill health through childhood and puberty. We describe a case series of infertility amongst women with PaHIV attending a London clinic between 2006 and 2017. Methods: A retrospective case-note review was conducted amongst all female PaHIV patients aged >16 years attending a London clinic...
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30800425/are-new-antiretroviral-treatments-increasing-the-risks-of-clinical-obesity
#6
EDITORIAL
Andrew Hill, Laura Waters, Anton Pozniak
There is growing evidence that the use of integrase inhibitors could lead to statistically significant increases in body weight and even clinical obesity, although it is unclear whether these changes are clinically significant. The effects of integrase inhibitors on body weight need to be analysed for women and by race, because current evidence suggests different effects. Potential additional effects of NRTIs on body weight need to be evaluated. Combined, standardised analyses of Phase 3 and independent clinical trials, with endpoints following the US Food and Drug Administration (FDA) guidelines where feasible, should be conducted to answer this question definitively...
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30800424/attrition-and-treatment-outcomes-among-adolescents-and-youths-living-with-hiv-in-the-thai-national-aids-program
#7
EDITORIAL
Sirinya Teeraananchai, Thanyawee Puthanakit, Stephen J Kerr, Suchada Chaivooth, Sasisopin Kiertiburanakul, Kulkanya Chokephaibulkit, Sorakij Bhakeecheep, Achara Teeraratkul, Matthew Law, Kiat Ruxrungtham
Background: There are limited data describing the care outcome of youth living with HIV in Asia. We assessed attrition and treatment outcomes among youths with behaviourly acquired HIV (BIY) and adolescents with perinatally acquired HIV (PIY) who initiated antiretroviral treatment (ART) through the National AIDS Program (NAP) in Thailand. Methods: People living with HIV aged 10-24 years who initiated antiretroviral therapy (ART) from 2008 to 2013 through the Thai NAP and who were followed up until 2014 were included in the analysis...
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30800423/stability-of-plasma-indices-of-inflammation-coagulation-and-homeostasis-after-fatty-and-non-fatty-meals-in-treated-people-with-hiv
#8
EDITORIAL
Dominic Dorazio, Douglas W Kitch, Netanya S Utay, Bernard J Macatangay, Alan Landay, Todd Brown, Ronald J Bosch, Alison L Pelger, Jane E Baum, Robert Asaad, Benigno Rodriguez, Michael M Lederman
Objectives: The relationship between lipid levels in plasma and inflammatory indices is complex and fatty meals alter plasma inflammatory markers in people with diabetes. There is interest in monitoring the effects of interventions on plasma inflammatory and coagulation elements in people with HIV, as they have been linked to risk for morbid outcomes and HIV persistence. Understanding the effects of feeding and time of specimen acquisition is important for the correct scheduling of clinical sampling...
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30800422/comparable-carotid-intima-media-thickness-among-long-term-virologically-suppressed-individuals-with-hiv-and-those-without-hiv-in-thailand
#9
EDITORIAL
Opass Putcharoen, Suwapan Pleumkanitkul, Aurauma Chutinet, Pongpat Vongsayan, Jitrada Samajarn, Jiratchaya Sophonphan, Stephen J Kerr, Akarin Hiransuthikul, Sarawut Siwamogsatham, Kiat Ruxrungtham, Anchalee Avihingsanon
Objectives: This study compared the carotid intima-media thickness (cIMT) among well suppressed adult participants living with HIV and adults without HIV, aged >45 years. Methods: A cross-sectional, age and sex-matched study was conducted at two sites in Thailand: King Chulalongkorn Memorial Hospital (KCMH) and HIV-NAT. All participants had no evidence of coronary artery disease (CAD). Ultrasonography of the carotid artery was measured by one well-trained neurologist who was blinded to the participants' care...
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30800421/safety-tolerability-and-impact-on-viral-reservoirs-of-the-addition-to-antiretroviral-therapy-of-abx464-an-investigational-antiviral-drug-in-individuals-living-with-hiv-1-a-phase-iia-randomised-controlled-study
#10
EDITORIAL
Sofie Rutsaert, Jean-Marc Steens, Paul Gineste, Basiel Cole, Sam Kint, P Noel Barrett, Jamal Tazi, Didier Scherrer, Hartmut J Ehrlich, Linos Vandekerckhove
Objectives: To assess the safety and tolerability as well as antiretroviral impact of ABX464, an oral investigational drug with a novel mechanism of HIV-1 inhibition (ClinicalTrials.gov NCT02735863). Methods: Randomised, double-blind, placebo-controlled, Phase IIa study in individuals living with HIV-1 on antiretroviral therapy at six clinical centres in Spain, France and Belgium. ABX464 was administered once a day to 22 fully controlled HIV-1-positive participants at two doses (50 mg, n =6 and 150 mg, n =16) versus placebo, which was given to eight participants for 28 days in combination with a boosted protease inhibitor (darunavir/ritonavir or darunavir/cobicistat)...
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30800420/establishment-of-latent-hiv-1-reservoirs-what-do-we-really-know
#11
EDITORIAL
Jef Vanhamel, Anne Bruggemans, Zeger Debyser
Despite our ability to suppress HIV-1 replication indefinitely in people on optimal combined antiretroviral therapy (cART), HIV-1 persists as a stably integrated and replication-competent provirus in a heterogeneous collection of long-lived cells (often referred to as 'latent reservoirs') in all individuals on treatment. Reactivation of these latent proviruses is believed to be responsible for the rebound viraemia that can be seen in nearly all people following treatment cessation. Hence, the persistence of HIV-1 in latent reservoirs remains one of the greatest challenges in current HIV cure research...
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30800419/of-hiv-and-men
#12
EDITORIAL
Christina K Psomas
No abstract text is available yet for this article.
January 1, 2019: Journal of Virus Eradication
https://read.qxmd.com/read/30515315/hiv-drug-resistance-in-sub-saharan-africa-public-health-questions-and-the-potential-role-of-real-world-data-and-mathematical-modelling
#13
EDITORIAL
Reneé de Waal, Richard Lessells, Anthony Hauser, Roger Kouyos, Mary-Ann Davies, Matthias Egger, Gilles Wandeler
The prevalence of pretreatment resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) is >10% in many low-income countries. As a consequence, several sub-Saharan African countries have implemented, or are considering the introduction of, non-NNRTI-based first-line antiretroviral therapy (ART) for treatment-naïve and treatment-experienced patients. This is occurring at a time when ART programmes are expanding, in response to the World Health Organization guidelines, which recommend ART initiation regardless of CD4 cell count...
November 15, 2018: Journal of Virus Eradication
https://read.qxmd.com/read/30515314/mathematical-modelling-to-inform-treat-all-implementation-in-sub-saharan-africa-a-scoping-review
#14
EDITORIAL
April D Kimmel, Rose S Bono, Olivia Keiser, Jean D Sinayobye, Janne Estill, Deo Mujwara, Olga Tymejczyk, Denis Nash
Objective: Despite widespread uptake, only half of sub-Saharan African countries have fully implemented the World Health Organization's 'treat all' policy, hindering achievement of global HIV targets. We examined literature on mathematical modelling studies that sought to inform scale-up and implementation of 'treat all' in sub-Saharan Africa. Methods: We conducted a scoping review, a research synthesis to assess emerging evidence and identify gaps, of peer-reviewed literature, extracting study characteristics on 'treat all' policies and assumptions, setting, key populations, outcomes and findings...
November 15, 2018: Journal of Virus Eradication
https://read.qxmd.com/read/30515313/traversing-the-cascade-urgent-research-priorities-for-implementing-the-treat-all-strategy-for-children-and-adolescents-living-with-hiv-in-sub-saharan-africa
#15
EDITORIAL
Leslie A Enane, Mary-Ann Davies, Valériane Leroy, Andrew Edmonds, Edith Apondi, Adebola Adedimeji, Rachel C Vreeman
Children and adolescents living with HIV (CALHIV) in sub-Saharan Africa experience significant morbidity and alarmingly high mortality rates due to critical gaps in the HIV care cascade, including late diagnosis and initiation of treatment, as well as poor retention in care and adherence to treatment. Interventions to strengthen the adult HIV care cascade may not be as effective in improving the cascade for CALHIV, for whom specific strategies are needed. Particular attention needs to be paid to the contexts of sub-Saharan Africa, where more than 85% of the world's CALHIV live...
November 15, 2018: Journal of Virus Eradication
https://read.qxmd.com/read/30515312/achieving-unaids-90-90-90-targets-for-pregnant-and-postpartum-women-in-sub-saharan-africa-progress-gaps-and-research-needs
#16
EDITORIAL
Lisa L Abuogi, John M Humphrey, Christian Mpody, Marcel Yotebieng, Pamela M Murnane, Kate Clouse, Lindah Otieno, Craig R Cohen, Kara Wools-Kaloustian
The implementation of the 2013 World Health Organization Option B+ recommendations for HIV treatment during pregnancy has helped drive significant progress in achieving universal treatment for pregnant and postpartum women in sub-Saharan Africa (SSA). Yet, critical research and implementation gaps exist in achieving the UNAIDS 90-90-90 targets. To help guide researchers, programmers and policymakers in prioritising these areas, we undertook a comprehensive review of the progress, gaps and research needs to achieve the 90-90-90 targets for this population in the Option B+ era, including early infant HIV diagnosis (EID) for HIV-exposed infants...
November 15, 2018: Journal of Virus Eradication
https://read.qxmd.com/read/30515311/substance-use-and-universal-access-to-hiv-testing-and-treatment-in-sub-saharan-africa-implications-and-research-priorities
#17
EDITORIAL
Kathryn E Lancaster, Angela Hetrick, Antoine Jaquet, Adebola Adedimeji, Lukoye Atwoli, Donn J Colby, Angel M Mayor, Angela Parcesepe, Jennifer Syvertsen
As universal testing and treatment for HIV, or 'treat all', expands across sub-Saharan Africa (SSA), substance use will likely have a negative impact on the success of scale-up efforts for antiretroviral treatment (ART). Overwhelming evidence highlights the negative impact of substance use on HIV care and treatment outcomes. Yet, as many countries in SSA expand ART, evidence of the extent of substance use, and its impact in the region, is more limited. Stigma, and the psychoactive effects of substance use, are barriers to seeking HIV treatment and adhering to ART regimens for persons with heavy alcohol use or substance use...
November 15, 2018: Journal of Virus Eradication
https://read.qxmd.com/read/30515310/mental-health-and-hiv-research-priorities-related-to-the-implementation-and-scale-up-of-treat-all-in-sub-saharan-africa
#18
EDITORIAL
Angela M Parcesepe, Charlotte Bernard, Robert Agler, Jeremy Ross, Marcel Yotebieng, Judith Bass, Edith Kwobah, Adebola Adedimeji, Joseph Goulet, Keri N Althoff
World Health Organization (WHO) guidelines call for antiretroviral therapy (ART) for all people living with HIV (PLWH) regardless of CD4 cell count, a policy often referred to as 'treat all'. This article seeks to: (1) provide an overview of mental health research among PLWH in sub-Saharan Africa (SSA) and interventions or strategies to address comorbid mental illness among those living with HIV; and (2) describe key mental health-related recommendations to inform the successful implementation and scale up of 'treat all' policies in SSA...
November 15, 2018: Journal of Virus Eradication
https://read.qxmd.com/read/30515309/iedea-who-research-policy-collaboration-contributing-real-world-evidence-to-hiv-progress-reporting-and-guideline-development
#19
EDITORIAL
Elizabeth Zaniewski, Olga Tymejczyk, Azar Kariminia, Sophie Desmonde, Valériane Leroy, Nathan Ford, Annette H Sohn, Denis Nash, Marcel Yotebieng, Morna Cornell, Keri N Althoff, Peter F Rebeiro, Matthias Egger
Partnerships between researchers and policymakers can improve uptake and integration of scientific evidence. This article describes the research-policy partnership between the International epidemiology Databases to Evaluate AIDS (IeDEA) ( www.iedea.org) and the World Health Organization (WHO), which was established in 2014. IeDEA is an international research consortium, which analyses data on almost 2 million people living with HIV under care in routine settings in 46 countries in Asia-Pacific, the Caribbean, Central and South America, North America and sub-Saharan Africa...
November 15, 2018: Journal of Virus Eradication
https://read.qxmd.com/read/30515308/the-contribution-of-observational-studies-in-supporting-the-who-treat-all-recommendation-for-hiv-aids
#20
EDITORIAL
Nathan Ford, Martina Penazzato, Marco Vitoria, Meg Doherty, Mary-Ann Davies, Elizabeth Zaniewski, Olga Tymejczyk, Matthias Egger, Denis Nash
In 2015, the World Health Organization (WHO) recommended that all people living with HIV (PLWH) should start antiretroviral therapy (ART) irrespective of clinical or immune status. This recommendation followed almost 20 years of research into the clinical and population-level benefits and risks of starting ART early compared with deferring treatment. This article summarises the ways in which observational data support the work of WHO, including the support provided by the International epidemiology Databases to Evaluate AIDS (IeDEA), taking the example of 'treat all'...
November 15, 2018: Journal of Virus Eradication
journal
journal
50095
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"