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IJC Heart & Vasculature

Jesse E Harris, Punit J Shah, Vijay Korimilli, Htut Win
Background: With the increased number of influenza cases observed during the 2017 - 2018 season, patients may be at a greater risk of cardiac related complications as a sequela of viral illness. We described the frequency of troponin elevations in patients with influenza infection during the 2017 - 2018 influenza season. Methods: This was a retrospective, single-center observational study. All patients aged 18 years or older and had laboratory confirmed influenza viral infection were included in the study...
March 2019: IJC Heart & Vasculature
Malin Nilsson, Kira Bang Bové, Elena Suhrs, Thomas Hermann, Sten Madsbad, Jens Juul Holst, Eva Prescott, Mette Zander
Objective: Glucagon-like-peptide-1 (GLP-1) receptor analogues have been shown to reduce cardiovascular events in patients with type 2 diabetes. However, the mechanism behind is still unknown. The aim of the study was to investigate the effect of intact GLP-1 (7-36) on coronary microcirculation in overweight adults. Design and methods: A double-blinded randomized cross-over study was performed, with 12 overweight participants. Effects of intact GLP-1 (7-36) infusion were compared with a saline infusion on separate days...
March 2019: IJC Heart & Vasculature
Alireza Sepehri Shamloo, Nikolaos Dagres, Boris Dinov, Philipp Sommer, Daniella Husser-Bollmann, Andreas Bollmann, Gerhard Hindricks, Arash Arya
Introduction: Although an undoubted association between epicardial fat tissue (EFT) and atrial fibrillation (AF) has been recently approved, the association between EFT and post-ablation AF recurrence is not evident yet. This study aimed to assess the association between EFT and AF recurrence after ablation. Methods: The present study was a systematic review and meta-analysis using related literature available in electronic databases until July 2018 via "atrial fibrillation" and "epicardial fat" as the main keywords...
March 2019: IJC Heart & Vasculature
Matthew Nudy, Vernon M Chinchilli, Andrew J Foy
Background: The 'Timing Hypothesis' states that the benefits and harms of hormone replacement therapy (HRT) are related to the proximity with which it is begun following the onset of menopause. The primary aim of this analysis was to test for heterogeneity of treatment effect for HRT using Chi2 and I2 tests for younger versus older initiators of HRT. The secondary aim was to perform a meta-regression with mean age at trial baseline as the covariate for various outcomes. Methods: Younger initiation trials were defined as those with mean age of participants <60 years and older initiation trials were those with mean age >60 years...
March 2019: IJC Heart & Vasculature
J Antonio González-Hermosillo, Manuel A Baños-González, Milton E Guevara-Valdivia, Jorge A Vázquez-Acosta, Manuel Odín de Los Ríos Ibarra, Kulio A Aguilar-Linares, Carlos Cantú-Brito, José L Leiva-Pons, Gerardo Pozas-Garza, Eddie A Favela-Pérez, Manlio F Márquez
Background: Atrial Fibrillation (AF) is associated with an increased risk of stroke and systemic embolism. Several studies have suggested that female AF patients could have a greater risk for stroke. There is scarce information about clinical characteristics and use of antithrombotic therapies in Latin American patients with nonvalvular AF. Objective: To describe the gender differences in clinical characteristics, thromboembolic risk, and antithrombotic therapy of patients with nonvalvular AF recruited in Mexico, an upper middle-income country, into the prospective national CARMEN-AF Registry...
March 2019: IJC Heart & Vasculature
Mayumi Kawai, Masahide Harada, Yuji Motoike, Masayuki Koshikawa, Tomohide Ichikawa, Eiichi Watanabe, Yukio Ozaki
Background: Since warfarin is primarily bound to serum albumin, hypoalbuminemia is likely to increase the free fraction of warfarin and to increase the risk of bleeding. We prospectively evaluated the impact of serum albumin levels (ALB) on international normalized ratio of prothrombin time (PT-INR) control and hemorrhagic events in atrial fibrillation (AF) patients treated with warfarin. Methods: Seven hundred fifty-five non-valvular AF patients on warfarin were enrolled...
March 2019: IJC Heart & Vasculature
HamidReza Pourhosseini, Reza Lashkari, Arya Aminorroaya, Danesh Soltani, Arash Jalali, Masih Tajdini
Introduction: Some studies have demonstrated that post-PCI elevated cardiac enzymes are associated with worse outcomes. In this study, we aimed to determine if high-dose treatment with atorvastatin before planned elective PCI reduces PMI or MACE at 1-year median follow-up. Material and methods: Eligible participants were randomly allocated to group A (80 mg atorvastatin 12 h and 40 mg 2 h before PCI) and group B (40 mg atorvastatin daily). Blood samples were obtained before and at 24 h after PCI to measure hsTnT...
March 2019: IJC Heart & Vasculature
Stefano Poli, Domenico Facchin, Francesca Rizzetto, Luca Rebellato, Elisabetta Daleffe, Mauro Toniolo, Antonella Miconi, Alessandro Altinier, Corrado Lanera, Stefano Indrigo, Jennifer Comisso, Alessandro Proclemer
Background: Non-sustained ventricular tachycardia (NSVT) can occur asymptomatically and can be incidentally detected in the internal records of pacemakers (PM). The clinical value of NSVT in the population of PM patients is still uncertain.Our aim was to assess the prevalence of NSVT detected by remote PM control, to describe the clinical and demographic characteristics of patients with NSVT, and to assess the prognostic significance of NSVT in terms of both overall and cardiovascular mortality...
March 2019: IJC Heart & Vasculature
Nami Takano, Eisuke Amiya, Gaku Oguri, Atsuko Nakayama, Masanobu Taya, Toshiaki Nakajima, Hiroyuki Morita, Issei Komuro
To investigate the effect of atrial fibrillation (AF) on the oxygen uptake and exercise tolerance, we evaluated cardiopulmonary exercise test (CPET) data in AF patients and heart rate-matched controls with sinus rhythm (cSR) who received ambulatory cardiac rehabilitation. We compared CPET data between AF ( N  = 27) and cSR patients ( N  = 106) who had similar HRs at rest and the peak points. Oxygen uptake (VO2 )/kg and relative O2 pulse (ml/bpm/kg) at rest and the anaerobic threshold (AT) level was not different between AF and cSR patients, but these parameters above the AT level were significantly lower in AF than in cSR patients...
March 2019: IJC Heart & Vasculature
Mohammed Faisaluddin, Kumar Ashish, Adrija Hajra, Samhati Mondal, Dhrubajyoti Bandyopadhyay
No abstract text is available yet for this article.
March 2019: IJC Heart & Vasculature
Michio Ogano, Yu-Ki Iwasaki, Ippei Tsuboi, Hidekazu Kawanaka, Masaharu Tajiri, Hisato Takagi, Jun Tanabe, Wataru Shimizu
Backgrounds: Some patients who undergo implantation of cardiac resynchronization therapy with defibrillator (CRT-D) survive long enough, thus requiring CRT-D battery replacement. Defibrillator therapy might become unnecessary in patients who have had significant clinical improvement and recovery of left ventricular ejection fraction (LVEF) after CRT-D implantation. Methods: Forty-nine patients who needed replacement of a CRT-D battery were considered for exchange of CRT-D for cardiac resynchronization therapy with pacemaker (CRT-P) if they met the following criteria: LVEF >45%; the indication for an implantable cardioverter defibrillator was primary prevention at initial implantation and no appropriate implantable cardioverter defibrillator therapy was documented after initial implantation of the CRT-D...
March 2019: IJC Heart & Vasculature
Angel M Alonso-Gómez, Lucas Tojal Sierra, Elena Fortuny Frau, Leire Goicolea Güemez, Ane Aboitiz Uribarri, María P Portillo, Estefanía Toledo, Helmut Schröder, Jordi Salas-Salvadó, Fernando Arós Borau
Background: Left ventricle diastolic dysfunction (LVDD) is a common finding in high risk individuals, its presence being associated with reduced exercise capacity (EC). We assessed the prevalence of LVDD, applying the 2016 guidelines of the American Society of Echocardiography (ASE)/European Association of Cardiovascular Imaging (EACVI), in a population with overweight/obesity and metabolic syndrome and its association with EC. Methods and results: This was a prospective, cross-sectional study of a cohort of 235 patients (mean age of 65 ± 5 years old and 33% female) without heart disease and an ejection fraction >50% who underwent a complete echocardiographic assessment and cardiopulmonary exercise testing...
March 2019: IJC Heart & Vasculature
Iryna Dykun, Daniela Wiefhoff, Matthias Totzeck, Fadi Al-Rashid, R Alexander Jánosi, Tienush Rassaf, Amir A Mahabadi
Background: We aimed to describe whether updated low-density lipoprotein (LDL)-targets in patients with manifest coronary artery disease (CAD) led to a change in lipid profile over time. Methods: We retrospectively included patients with manifest CAD from 2009-2010, 2012-2013, and 2015-2016 (n = 500 each). Lipid levels and medication at the different time-points as well as rate of accordance to guidelines (<100 for 2009-2010, <70 mg/dl for 2012-2013 and 2015-2016) were evaluated...
March 2019: IJC Heart & Vasculature
Chengzhi Chen, Jingyan Liu, Zhiyong Liu, Xin He, Xuming Yuan, Xiufen Ouyang, Lei Wang, Xiaoping Li
Objective: To the authors' knowledge, limited data are available regarding the association between Electrocardiogram (ECG) signs of right ventricular hypertrophy (RVH) and pulmonary hypertension (PH) in patients with dilated cardiomyopathy (DCM). We aimed to assess the accuracy of the recommended ECG criteria of RVH for predicting PH in patients with DCM. Methods: According to the definition of PH (mPAP ≥ 25 mm Hg), 35 patients with DCM were divided into 2 groups: DCM with PH (n = 22) and DCM without PH (n = 13)...
March 2019: IJC Heart & Vasculature
Kentaro Ejiri, Toru Miyoshi, Kunihisa Kohno, Makoto Nakahama, Masayuki Doi, Mitsuru Munemasa, Masaaki Murakami, Atsushi Takaishi, Kazufumi Nakamura, Hiroshi Ito
Background: Remote ischemic preconditioning (RIPC) is promising for preventing periprocedural myocardial damage (pMD) in patients undergoing percutaneous coronary intervention (PCI). However, the impact of RIPC on pMD on smokers is not well elucidated. The aim of this study was to investigate an association between tobacco smoking and RIPC on pMD in patients planning to undergo PCI. Methods: This study used data from a multicenter randomized controlled trial involving patients with stable angina who planned to undergo elective PCI...
March 2019: IJC Heart & Vasculature
Rahul Samanta, Arun Narayan, Pramesh Kovoor, Aravinda Thiagalingam
Background: There is limited data regarding long-term survival in patients who present with STEMI and out of hospital cardiac arrest (OHCA). Methods: We prospectively analysed outcomes in 3521 consecutive patients who were diagnosed with STEMI and underwent primary percutaneous coronary intervention (PPCI) or coronary artery bypass surgery from 2004 to 2017. They were divided into two groups according to the presence of cardiac arrest (group I, patients with cardiac arrest; n  = 156 group II, patients without cardiac arrest; n  = 3365)...
March 2019: IJC Heart & Vasculature
Kumar Ashish, Mohammed Faisaluddin, Dhrubajyoti Bandyopadhyay, Adrija Hajra, Eyal Herzog
No abstract text is available yet for this article.
March 2019: IJC Heart & Vasculature
Mohammed Faisaluddin, Dhrubajyoti Bandyopadhyay, Adrija Hajra, Hassan Beydoun, Raktim K Ghosh, Eyal Herzog
No abstract text is available yet for this article.
March 2019: IJC Heart & Vasculature
Enrico Cerrato, Matteo Bianco, Akshay Bagai, Leonardo De Luca, Simone Biscaglia, Alessia Luciano, Paola Destefanis, Giorgio Quadri, Ilaria Meynet, Carol Gravinese, Alessandra Chinaglia, Shaun G Goodman, Roberto Pozzi, Gianluca Campo, Ferdinando Varbella
Introduction: The efficacy and safety of switching P2Y12 receptor antagonists in patients admitted for acute coronary syndrome (ACS) remain unclear. We assessed the short-term clinical outcomes (in-hospital and within 30 days) of switching P2Y12 inhibitor (P2Y12 I) drugs versus maintaining the same regimen by performing a comprehensive review and meta-analysis of available data. Methods: MEDLINE/PubMed/SCOPUS/Cochrane databases were screened for studies regarding switching of P2Y12 I in patients with ACS that reported 30 days follow-up...
March 2019: IJC Heart & Vasculature
Faisal Qadir, Tariq Ashraf, Kanwal Fatima Aamir, Abdul Samad Achakzai, Syed Muhammad Afaque, Muhammad Nauman Khan, Najia Aslam Soomro, Simran Salman Qureshi, Musa Karim
Background: Longstanding severe rheumatic mitral stenosis (MS) is associated with changes in the atrial chamber dimensions. It is not known whether there is an increased thickness of the inter-atrial septum (IAS) in patients with severe rheumatic mitral stenosis. The objective of this study was to evaluate pre-procedural IAS thickness by echocardiography in patients with moderate to severe rheumatic mitral stenosis undergoing percutaneous balloon mitral valvuloplasty (PBMV). Methods: The thickness of the IAS was measured by transesophageal echocardiography (TEE) in 86 patients between 14 and 65 years of age...
March 2019: IJC Heart & Vasculature
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