Moussa Toudou-Daouda, Roger-Venant Yatwa-Zaniwe, Nana-Rahamatou Aminou-Tassiou, Nicolas Chausson, Didier Smadja
We report the case of a male in his 50s with a history of smoking admitted to our hospital for three transient recurrent episodes of less than 60 min of cheiro-oral paresthesias and binocular horizontal diplopia with convergent strabismus. On admission, his neurological examination was normal. Cerebral magnetic resonance imaging showed no cerebral lesion. Computed tomography angiography showed a sub-occlusive right carotid bulb atherosclerotic stenosis, the absence of abnormality of the subclavian arteries and the origin of the vertebral arteries, and no stenosis of the basilar artery or posterior cerebral arteries...
March 2024: Oxford Medical Case Reports
Teona Mskhaladze, David Tchkonia, Kakha Vacharadze, Nana Kiria, Mikolay Chkonia
INTRODUCTION: Enhancing the efficacy of treatment for Multi-Drug Resistant (MDR) and Extensively Drug Resistant (XDR) Tuberculosis has prompted exploration into adjunctive therapies, such as Endobronchial Valve Placement (EVP) in addition to pharmacological interventions. MATERIALS AND METHODS: EVP was performed utilizing a combination of rigid and flexible bronchoscopes to address airway hemorrhage and facilitate closure of TB cavities. The procedure involved the deployment of large valves (12 mm and 17 mm), necessitating the utilization of a rigid bronchoscope...
March 2024: Oxford Medical Case Reports
Tomohiro Nakajima, Keitaro Nakanishi, Tsuyoshi Shibata, Keishi Ogura, Nobuyoshi Kawaharada
No abstract text is available yet for this article.
March 2024: Oxford Medical Case Reports
Mohamed Badie Ahmed, Khaled E Elzawawi, Ayda AlHammadi, Aysha Al-Malki, Mahir Petkar, Salim Al Lahham, Abeer Alsherawi
Spiroadenomas, arising from sweat glands, are rare benign skin tumors primarily found as solitary nodules on the head, neck, and trunk. The malignant subtype, Spiradenocarcinoma (MSA), originating from benign spiradenomas, is extremely rare and occurs mainly in individuals over 50. MSA exhibits aggressiveness with higher metastasis rates and lower survival rates. Surgical excision is the standard management, supported by imaging modalities like MRI, CT-scan, and ultrasound. We present a 69-year-old female with a medical history of diabetes, hypertension, and dyslipidemia who presented in 2014 with multiple swellings on the forehead and left arm...
March 2024: Oxford Medical Case Reports
Yeliz Aka, Hulya Ozdemir, Nese Torun, Filiz Aka Bolat, Ozgur Kutuk
Metastatic breast cancer remains to be a major cause of cancer-related deaths in women. Exploring the molecular mechanisms to identify targetable alterations in progressing breast cancer and developing functional tools to predict therapy response in these patients are needed. In this report, we present a case of breast cancer patient who progressed following surgery and adjuvant endocrine therapy. Radiological and pathological analyses revealed metastasis to liver and brain. Paired liquid biopsies demonstrated acquired ERBB2 mutations in addition to TP53 and PIK3CA mutations, which were also present before progression...
March 2024: Oxford Medical Case Reports
Tsuyoshi Hirata, Naoko Kubota, Kazuaki Fukushima, Erika Takami, Tsuyoshi Kato, Tomomi Okamoto
An 80-year-old man presented in December with the main complaint of jaundice. Blood tests revealed hemolytic anemia and renal dysfunction. Positive syphilis serology results led to a diagnosis of untreated latent syphilis. A positive direct Coombs test led to a diagnosis of autoimmune hemolytic anemia (AIHA). Antibiotics were started for the syphilis, with improvement in the anemia and renal dysfunction observed. However, paroxysmal intravascular hemolysis occurred after his discharge. Based on a positive Donath-Landsteiner (D-L) test, paroxysmal cold hemoglobinuria (PCH) diagnosis was made...
March 2024: Oxford Medical Case Reports
Yotsapon Thewjitcharoen, Egkaluck Wanothayaroj, Veekij Veerasomboonsin
No abstract text is available yet for this article.
March 2024: Oxford Medical Case Reports
Amrita Shrestha, K C Kusha, Abal Baral
This paper presents a case of Moth-Eaten Alopecia as the only clinical manifestation of secondary syphilis in a 28-year-old man from Nepal. The patient exhibited progressive hair loss in the occipitoparietal region without associated pain or itching. With a positive Rapid Plasma Reagin (RPR) test (1:256), the patient received a three-week course of Benzathine Penicillin G, resulting in complete hair regrowth within four months. This case underscores the significance of recognizing moth eaten alopecia as a potential dermatological sign of secondary syphilis, especially when it appears as the sole clinical symptom...
March 2024: Oxford Medical Case Reports
Fares A AlKhayal, Moath K Albusair
Syphilis is a sexually transmitted disease caused by the spirochete bacterium Treponema pallidum. Syphilis is a significant public health issue, notably in (HIV) positive patients. Due to the absence of pathognomonic signs in secondary syphilis and its ability to present and mimic a wide variety of clinical findings, it gained the name "the Great imitator '(mimicker).' Herein, we describe a case of a 51-year-old man who presented with acute painless loss of vision of the right eye preceded by a few erythematous plaques with thick scales over bilateral legs and multiple discrete and confluent scaly papules over the palms and soles...
March 2024: Oxford Medical Case Reports
Osamu Imataki, Makiko Uemura
We treated a 78-year-old Japanese man with gastric diffuse large B cell lymphoma. The patient received three courses of chemotherapy and involved-field local radiation therapy to the stomach. Three years after chemotherapy, the patient become sick with anorexia and pancytopenia. He was cachexic, however, levels of vitamin B12, folate, zinc, and copper were normal. His bone marrow revealed focal eosinophilic deposit characterized by mixture of vivid atrophic fatty cells, which was pathologically diagnosed as gelatinous bone marrow...
March 2024: Oxford Medical Case Reports
Mansoor Aslamzai, Turyalai Hakimi, Mesbahullah Mushoud, Abdul Hakim Mukhlis
Noninvoluting congenital hemangioma is an extremely rare congenital anomaly in newborn babies and may complicate life-threatening events, including hemorrhage. We present a very rare case of noninvoluting congenital hemangiomas in an Asian and Afghan six-day-old girl that was detected at birth. The noninvoluting congenital hemangiomas were accompanied by hypovolemic shock, anemia, and prolonged jaundice during the first two weeks of life. These diseases were diagnosed by medical history, physical examination, blood analysis, and doppler ultrasonography of the skin lesions...
March 2024: Oxford Medical Case Reports
Aya Kuroyanagi, Chiaki Inano, Junko Adachi, Goro Kaneko, Hideki Toyokawa
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most difficult-to-alleviate side effects of chemotherapy, impacting the patient's daily activities and quality of life and frequently necessitating the discontinuation or dose reduction of anticancer drugs. An effective treatment for CIPN is yet to be established. Herein, we report the case of a patient who developed CIPN after receiving paclitaxel as postoperative chemotherapy for breast cancer. The patient experienced difficulties in performing daily activities owing to pain in her fingers and toes despite attempts to treat these symptoms with medications...
February 2024: Oxford Medical Case Reports
Hailey Konisky, Hubert Huho, Aashka Suvarnakar, Sharma Krishna, Albert Huho
These medical case reports discuss the reflectance confocal microscopy (RCM) features of palisaded encapsulated neuromas (PEN), a relatively uncommon benign neural tumor that predominantly manifests in middle-aged females, most notably on the facial cheek. These reports feature two middle-aged females who both presented with concern for progressively enlarging cheek papules. Dermoscopy revealed the presence of symmetrical, dome-shaped papules with arborizing blood vessels that were not in sharp focus. RCM images revealed a honeycomb pattern, replete with follicular openings and slight papillary dermal fibrosis...
February 2024: Oxford Medical Case Reports
Omair Khan, Sadia Aslam, Fatemeh Mohammadrezaei, Rita Dennise Moncayo Wilches, Joseph Mehrabi, Matania Yehounatan, Sapna Kumari, Sehajpreet Singh, Maryam Ahmadi, Daniel Masri, Sarita Konka, Yevgeniya Margulis
Rheumatoid arthritis (RA) is a chronic inflammatory condition primarily affecting the musculoskeletal system but can often involve other organ systems as well. Rheumatoid meningitis is a rare central nervous system (CNS) manifestation of RA characterized by pachymeningeal and leptomeningeal enhancement. Herein, we present a case of a 64-year-old male who presented with left lower extremity weakness and witnessed seizures. The diagnostic work-up, including lumbar puncture, brain MRI and meningeal biopsy ruled out malignancy and were consistent with the diagnosis of rheumatoid meningitis...
February 2024: Oxford Medical Case Reports
Murari Prasad Barakoti, Mohamed Shafiu, Kaushal Kishore Tiwari, Sadip Pant
Single coronary artery is a rare congenital anomaly in which a single coronary artery arises from the aortic root that supplies the entire heart. It has variable clinical presentations ranging from a completely benign course to sudden cardiac death. Identifying and categorizing to high-risk type based on clinical presentation and anatomical features can present adverse cardiac events and provides better prognosis.
February 2024: Oxford Medical Case Reports
Marah Omer, Yavuz Yigit, Baha Hamdi Alkahlout, Eslam Hussein Mohamed, Sulafa Khalil, Aftab Mohammad Azad
Tizanidine withdrawal is a rare and complex phenomenon characterized by a surge in adrenergic activity upon abrupt discontinuation of the drug. We present a unique case of a 41-year-old male with multiple comorbidities who self-administered an exceptionally high daily dose of Tizanidine, leading to severe withdrawal symptoms. This case report highlights the challenges in managing such cases. The patient, with a history of myofascial pain syndrome, hypertension, anxiety, and depression, experienced distressing symptoms, including tachycardia, rebound hypertension, neuropsychiatric manifestations, and involuntary muscle movements...
February 2024: Oxford Medical Case Reports
Israr Khan, Adam Atoot
Takotsubo syndrome occurs predominantly in women and is usually preceded by acute emotional and/or physical stress. Patients commonly present with chest pain and/or dyspnea. Syncope or out-of-hospital cardiac arrest is a rare presentation. We report an unusual case of takotsubo syndrome in an elderly patient who presented with left facial droop, slurred speech, and syncopal episode. Initial presumed diagnosis was an ischemic stroke/transient ischemic attack. However, the patient was then treated for acute myocardial ischemia/infarction based on abnormal electrocardiogram, elevated cardiac troponin, and unremarkable neurological workup...
February 2024: Oxford Medical Case Reports
Shahd Asfer, Suhair Hmidan Samsam, Rama Zakkar, Habib Jarbouh
Uterine carcinosarcoma (UCS), also known as malignant mixed Müllerian tumor, is a rare malignancy, which consists of both carcinomatous and sarcomatous elements, with a clinical picture resembling endometrial carcinoma. We report a case of a 74-year-old woman is reported with UCS, diagnosed after a 7 months history of vaginal bleeding and abdominal pain. Previous transvaginal sonography showed nonspecific findings, but a repeated one revealed a central uterine mass. Dilatation and curettage and several biopsies were performed...
February 2024: Oxford Medical Case Reports
Hala Khaddam, Kheder Kheder, Rami Sabouni, Younes Al Mahmoud, Rasha Nabhan
Mucocutaneous leishmaniasis (MCL) is a leishmania infection; that usually affects the oral and nasal mucosa. The coexistence of leishmania and malignancy is rarely reported and mainly in immunocompromised patients. We report a case of an overlapping between leishmania and squamous cell carcinoma (SCC) in a 60-year-old immunocompetent Syrian female. The patient presented with a one-year crusty nodule on the lower lip. Since she lives in an endemic region, leishmaniasis was suggested, and confirmed with a Giemsa-stained smear...
February 2024: Oxford Medical Case Reports
Dimitrios Diamantidis, Nikolaos Papatheodorou, Panagiotis Kostoglou, Georgios Tsakaldimis, Sotirios Botaitis
Vesicoenteric fistulas are rare, with an incidence of 0.1%-0.2% in the general population, and Meckel's diverticulum is a rare cause, accounting for less than 5% of cases with challenging diagnosis due to atypical symptoms at the admission. This article presents a case of a vesicoenteric fistula formation between Meckel's diverticulum perforated by a foreign body and urinary bladder in a 38-years-old Caucasian male admitted to emergency department due to colicky abdominal pain located in the lower abdomen. An extensive review of the literature was conducted referring all the cases of vesicoenteric fistula incorporating Meckel's diverticulum to elucidate the clinical characteristics, explore the diagnostic yield, and to summarize the therapeutic approach...
February 2024: Oxford Medical Case Reports
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