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Endoscopy International Open

Thomas Walter
For the management of diminutive duodenal neuroendocrine tumors (d-NETs), Harshit et al. have proposed - in the work accompanying this editorial - an interesting approach, the endoscopic banding without resection (BWR) technique. Given the risks associated with classic endoscopic resections and surgical procedures, and the likely favorable natural history of diminutive d-NETs, BWR may be an option for these selected patients with a very low risk of LN + and recurrence. However, a close follow-up (endoscopic, EUS and thoraco-abdominal CT scan) is then required to guarantee the safety of this policy...
February 2019: Endoscopy International Open
Harshit S Khara, Gerald J Shovlin, Amitpal S Johal, David L Diehl
Endoscopic treatment of diminutive (less than 10 mm) duodenal neuroendocrine tumors (NETs) is recommended because of the risk of metastatic potential. Endoscopic mucosal resection and endoscopic submucosal dissection are alternatives to surgical management but have significant adverse event rates. We evaluated the effectiveness, feasibility, and safety of the 'banding without resection' (BWR) technique and assessed outcomes for the treatment of diminutive duodenal NETs. Our study included eight patients referred for endoscopic treatment of incidentally discovered, biopsy proven, diminutive duodenal bulb NETs...
February 2019: Endoscopy International Open
Benjamin Walter, Simone Schmidbaur, Yannick Krieger, Alexander Meining
Background  En-bloc resection of large, flat lesions or early stages of cancer is challenging. No bimanual tasks are possible using standard endoscopes. Dual-channel endoscopes are not available everywhere and have a small distance between the channels. Patients and methods  A new external additional working channel (AWC) (Ovesco, Tuebingen, Germany) was designed and developed potentially enabling bimanual tasks. Fixed to the tip of a standard gastroscope or pediatric colonoscope, a second endoscopic tool can be inserted through the AWC and used for tissue retraction during endoscopic resection...
February 2019: Endoscopy International Open
Henry H L Wu, James E East
No abstract text is available yet for this article.
February 2019: Endoscopy International Open
Andrea Kresz, Benjamin Mayer, Maria Zernickel, Carsten Posovszky
Background and study aims  Use of carbon dioxide (CO 2 ) instead of room air (RA) during colonoscopy in adults revealed significantly less flatulence and abdominal pain in several studies. The objectives of this study were to investigate the effects of CO 2 usage on post-interventional pain, abdominal discomfort, abdominal girth, pCO 2 levels, and narcotic requirement in deeply sedated pediatric patients. Patients and methods  A total of 97 children and adolescents aged 4 years to 17 years undergoing colonoscopy were randomized to RA or CO 2 in a prospective, randomized, controlled trial...
February 2019: Endoscopy International Open
Kevin Singh, Ayla Zubair, Andrew Prindle, Ahmed Jamal Nadeem, Gulam Khan
Background and study aims  Small bowel arteriovenous malformations (AVMs) pose a bleeding risk and have traditionally been diagnosed by invasive enteroscopic procedures in patients with hereditary hemorrhagic telangiectasia (HHT). Capsule endoscopy (CE) is emerging as a safe and non-invasive alternative for small intestinal evaluation, but its diagnostic yield and utility in diagnosing small bowel AVMs in HHT patients are understudied. The aim of this study was to meta-analyze the utility of CE for diagnosing AVMs in HHT patients...
February 2019: Endoscopy International Open
Shoichi Yoshimizu, Yorimasa Yamamoto, Yusuke Horiuchi, Toshiyuki Yoshio, Akiyoshi Ishiyama, Toshiaki Hirasawa, Tomohiro Tsuchida, Junko Fujisaki
Background and study aims  Delineating undifferentiated-type early gastric cancer (UD-type EGC) from noncancerous areas is difficult. Therefore, the lateral margin negative (LM-) resection rate of endoscopic submucosal dissection (ESD) is lower for UD-type EGC than for differentiated-type EGC. This study aimed to retrospectively evaluate the effectiveness of the marking methods with circumferential biopsies in ESD for UD-type EGC. Patients and methods  We analyzed the clinical outcomes of ESD in 127 patients with UD-type EGC between April 2013 and 2017...
February 2019: Endoscopy International Open
Harminder Singh, Donald R Duerksen, Gale Schultz, Carol Reidy, Pat DeGagne, Nancy Olson, Zoann Nugent, Michelle J Alfa
Background and study aims  Prevention of infection transmission from contaminated endoscopes would benefit from a rapid test that could detect low levels of viable bacteria after high level disinfection. The aim of this study was to evaluate the rapid NOW! (RN) test's ability to detect endoscope contamination. Materials and methods  The RN test kit and the accompanying fluorometer were evaluated. The manufacturer states that a fluorometer signal > 300 units is indicative of viable Gram-negative bacteria...
February 2019: Endoscopy International Open
Massimiliano Mutignani, Edoardo Forti, Alberto Larghi, Stefanos Dokas, Francesco Pugliese, Marcello Cintolo, Giulia Bonato, Alberto Tringali, Lorenzo Dioscoridi
Background and study aims  Endoscopic therapy for postoperative Bergmann type A bile leaks is based on biliary sphincterotomy ± stent insertion. However, recurrent or refractory bile leaks can occur. Patients and methods  This was retrospective study including all consecutive patients who were referred to our center with a Bergmann type A bile leak refractory to previous conventional endoscopic treatments. Results  Seventeen patients with post-cholecystectomy-refractory Bergmann type A bile leak were included...
February 2019: Endoscopy International Open
Pedro Russo, Sandra Barbeiro, Halim Awadie, Diogo Libânio, Mario Dinis-Ribeiro, Michael Bourke
Objective and study aims  To evaluate the efficacy and safety of different endoscopic resection techniques for laterally spreading colorectal tumors (LST). Methods  Relevant studies were identified in three electronic databases (PubMed, ISI and Cochrane Central Register). We considered all clinical studies in which colorectal LST were treated with endoscopic resection (endoscopic mucosal resection [EMR] and/or endoscopic submucosal dissection [ESD]) and/or transanal minimally invasive surgery (TEMS). Rates of en-bloc/piecemeal resection, complete endoscopic resection, R0 resection, curative resection, adverse events (AEs) or recurrence, were extracted...
February 2019: Endoscopy International Open
Li-Chun Chang, Chia-Tung Shun, Wen-Feng Hsu, Chia-Hong Tu, Chieh-Chang Chen, Ming-Shiang Wu, Han-Mo Chiu
Background and study aims  Cold snare polypectomy (CSP) is considered to be effective in reducing risk of delayed bleeding but randomized trials fail to support this owing to the small sample size. The current study aimed to compare risk of delayed bleeding before and after implementation of CSP in a screening colonoscopy setting. Patients and methods  This study retrospectively analyzed a prospectively maintained screening colonoscopy database in a university hospital in Taiwan. We compared the rate of delayed bleeding before and after implementation within similar periods (18 months and 15 months) and the respective number of polypectomies (1,304 and 1,255) performed to remove small and diminutive polyps...
February 2019: Endoscopy International Open
Shajan Peter, Nipun B Reddy, Mohammed Naseemuddin, Jenine N Zaibaq, Gerald McGwin, C Mel Wilcox
Background and study aims  Colonoscopy can be technically challenging and cause discomfort in patients. The integrated Scope Guide assist is built in to show that with its use outcomes are improved during colonoscopy. We aimed to test the usefulness of the Magnetic Scope Guide Assist (ScopeGuide ) with respect to cecal intubation time, and other procedural quality outcomes. Patients and methods  We conducted a prospective study of outpatients undergoing elective colonoscopy at the endoscopic units of the University of Alabama at Birmingham (UAB) from March 2016 to July 2016...
February 2019: Endoscopy International Open
Madhav Desai, Venkat Nutalapati, Ajay Bansal, Daniel Buckles, John Bonino, Mojtaba Olyaee, Amit Rastogi
No abstract text is available yet for this article.
February 2019: Endoscopy International Open
Pedro N Figueiredo, Isabel N Figueiredo, Luís Pinto, Sunil Kumar, Yen-Hsi Richard Tsai, Alexander V Mamonov
Background and study aims  Detection of polyps during colonoscopy is essential for screening colorectal cancer and computer-aided-diagnosis (CAD) could be helpful for this objective. The goal of this study was to assess the efficacy of CAD in detection of polyps in video colonoscopy by using three methods we have proposed and applied for diagnosis of polyps in wireless capsule colonoscopy. Patients and methods  Forty-two patients were included in the study, each one bearing one polyp. A dataset was generated with a total of 1680 polyp instances and 1360 frames of normal mucosa...
February 2019: Endoscopy International Open
Pilar Diez Redondo, Henar Núñez Rodríguez, Marina de Benito Sanz, Raúl Torres Yuste, Manuel Pérez-Miranda
Background and study aims  Zenker's diverticulum may cause disabling symptoms, especially in the elderly. Treatment has changed in recent decades from open surgery to management with flexible endoscopy, resulting in lower morbidity and mortality. The goal of this study was to present the largest series, with the longest follow-up, of patients with Zenker's diverticulum receiving outpatient treatment with flexible endoscopy using a diverticuloscope and Ligasure (Covidien, Minneapolis, Minnesota, United States), a device that allows tissue sealing and coagulation of vessels before cutting the septum between the diverticulum and esophagus...
February 2019: Endoscopy International Open
G Hoff, E Botteri, O Høie, K Garborg, H Wiig, G Huppertz-Hauss, V Moritz, M Bretthauer, Ø Holme
No abstract text is available yet for this article.
February 2019: Endoscopy International Open
En-Ling Leung Ki, Anne-Isabelle Lemaistre, Fabien Fumex, Rodica Gincul, Christine Lefort, Vincent Lepilliez, Bertrand Pujol, Bertrand Napoléon
Background and aims  This study aimed to evaluate the performance of Macroscopic On-site Evaluation (MOSE) using a novel endoscopic ultrasound (EUS) fine needle biopsy (FNB) needle (22-G Franseen-tip needle, Acquire, Boston Scientific Incorporated, Boston, Massachusetts, United States), and without using Rapid On-Site Evaluation (ROSE). Method  Between May 2016 and August 2016, all consecutive patients referred to our center for EUS tissue acquisition (TA) for solid lesions underwent EUS-FNB with the 22-G Franseen-tip needle unless contra-indicated...
February 2019: Endoscopy International Open
Daniel Gaballa, Catherine S Abendroth, Matthew T Moyer
Background and study aims  Endoscopic ultrasound (EUS)-guided chemoablation with ethanol lavage, followed by infusion with paclitaxel, has been found to be effective for treatment of mucinous pancreatic cysts. However, there are notable adverse events (AEs) associated with ethanol and its undesirable inflammatory effects on local tissue and vessels. The recent ChARM trial demonstrated that removing ethanol from the cyst ablation process resulted in equivalent efficacy while significantly reducing associated AEs...
February 2019: Endoscopy International Open
W F Kappelle, J E van Hooft, M C W Spaander, F P Vleggaar, M J Bruno, F Maluf-Filho, A Bogte, E van Halsema, P D Siersema
Background and study aims  Fully covered self-expanding metal stents (FCSEMS) provide an alternative to bougie dilation (BD) for refractory benign esophageal strictures. Controlled studies comparing temporary placement of FCSES to repeated BD are not available. Patients and methods  Patients with refractory anastomotic esophageal strictures, dysphagia scores ≥ 2, and two to five prior BD were randomized to 8 weeks of FCSEMS or to repeated BD. The primary endpoint was the number of BD during the 12 months after baseline treatment...
February 2019: Endoscopy International Open
Landon K Brown, Norman R Clark, Jason Conway, Girish Mishra
Background and study aims  The merits of rectal ultrasound for rectal cancer staging are well documented. Conventional approaches to accessing perirectal and presacral lesions entail computed tomography guidance via a transgluteal approach or frank surgical exploration. We report on the safety and efficacy of performing rectal ultrasound with fine-needle aspiration (RUS-FNA) for evaluating perirectal, presacral, and pelvic abnormalities. Patients and methods  Patients who underwent RUS-FNA of perirectal, presacral, or pelvic lesions between August 2005 and September 2016 were identified using an institutional database...
February 2019: Endoscopy International Open
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