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Journal of Pharmacopuncture

Hamid Reza Sodagari, Zahra Aryan, Amir Hossein Abdolghaffari, Nima Rezaei, Amirhossein Sahebkar
No abstract text is available yet for this article.
December 2018: Journal of Pharmacopuncture
Fereshteh Asgharzadeh, Rahimeh Bargi, Farimah Beheshti, Mahmoud Hosseini, Mehdi Farzadnia, Majid Khazaei
Objectives: Thymoquinone (TQ) is one of the active ingredients of herbal plants such as Nigella sativa L. (NS) which has beneficial effects on the body. The beneficial effects of TQ on the cardiovascular system have reported. This study aimed to investigate the effect of TQ on cardiac fibrosis and permeability, serum and tissue concentration of inflammatory markers and oxidative stress status in chronic lipopolysaccharide exposure in male rats. Methods: Seventy male Wistar rats were randomly divided into five groups as follows: (1) control; (2) LPS (1 mg/kg/day); (3-5) LPS + TQ with three doses of 2, 5 and 10 mg/kg (n=14 in each group)...
December 2018: Journal of Pharmacopuncture
Maryam Shoja, Soghra Mehri, Bahareh Amin, Vahid Reza Askari, Hossein Hosseinzadeh
Objectives: Ethanol withdrawal following its chronic use is a serious outcome and challenging to treatment. The chronic use of ethanol induces a progressive neuroplasticity in different reigns of brain. In this study we evaluated the effects of aqueous extract of Crocus sativus L. (saffron) and its active compound, crocin, on the withdrawal behavior induced after repeated administration of ethanol, in two regimens of prophylactic (administration of drugs concomitant with the induction of dependence) and treatment (administration of drugs during the period of ethanol withdrawal) in mice which received ethanol...
December 2018: Journal of Pharmacopuncture
Hyun-Ji Park, Shin-Hyung Park
Objectives: The purpose of this study is to investigate the anti-cancer effects of different fractions of Astragalus membranaceus (AM) in human non-small cell lung cancer (NSCLC) cells. Methods: We isolated hexane, ethyl acetate, and butanol fractions from crude ethanol extract of AM. The cell death was examined by MTT assay and trypan blue exclusion assay. Apoptosis was detected by DAPI staining, annexin V-PI double staining and cell cycle analysis. The expression of apoptosis-related proteins and mitogen-activated protein kinases (MAPKs) was examined by western blot...
December 2018: Journal of Pharmacopuncture
Hye-Min Ryu, Seung-Jeong Lee, Eun-Jin Park, Su-Gyeong Kim, Kyeong Han Kim, Yoo Min Choi, Jong Uk Kim, Beom Yong Song, Cheol Hong Kim, Hyun-Min Yoon, Tae-Han Yook
Objectives: The purpose of this study was to find out validity of Surface Electromyography(sEMG) compared with Nerve Conduction Study and clinical assessment scale as assessment factors for facial palsy. Methods: We investigated 50 cases of patients with peripheral facial palsy who had records of sEMG and NCS to check. Then we analyzed the correlation between sEMG and NCS that carried out around 1 week after onset. And we analyzed the correlation between sEMG and clinical assessment scales that were measured three times around 1 week, 3-4 weeks and 5-6 weeks after onset...
December 2018: Journal of Pharmacopuncture
Reza Mohebbati, Maryam Paseban, Farimah Beheshti, Mohammad Soukhtanloo, Mohammad Naser Shafei, Hasan Rakhshandeh, Abolfazl Khajavi Rad
Objectives: The hepatotoxicity induced by Acetaminophen (AAP) mostly mediated by effect on oxidative stress parameters. The Zataria multiflora (Z.M) is an herbal medicine with well-known antioxidant effect. The aim of this study is investigation of preventive effects of Z.M and Carvacrol (CAR) on AAP-induced hepatotoxicity in rats. Methods: Rats were randomly divided into four groups including: 1) Control, 2) Acetaminophen (AAP), 3) and 4) CAR. The saline, Z.M (200 mg/kg) and CAR (20 mg/kg) were administrated orally for 6 days, after that AAP (600 mg/kg) was administrated in the 7th day...
December 2018: Journal of Pharmacopuncture
Yunna Kim, Seung-Hun Cho
Objectives: Pharmacopuncture is a treatment that medicinal fluid including herbal extract is injected in body under qi/flavor theory and meridian theories. There are a number of studies investigating the efficacy of pharmacopuncture for cervicogenic dizziness but its usage differs in each study. This study aimed to review previous studies of pharmacopuncture treatment for cervicogenic dizziness to navigate the direction of improvement. Methods: Literature review was conducted on studies aimed at pharmacopuncture for cervicogenic dizziness...
December 2018: Journal of Pharmacopuncture
Yunes Panahi, Mojtaba Mojtahedzadeh, Atabak Najafi, Seyyed Mahdi Rajaee, Mohammad Torkaman, Amirhossein Sahebkar
Neuroprotection or prevention of neuronal loss is a complicated molecular process that is mediated by various cellular pathways. Use of different pharmacological agents as neuroprotectants has been reported especially in the last decades. These neuroprotective agents act through inhibition of inflammatory processes and apoptosis, attenuation of oxidative stress and reduction of free radicals. Control of this injurious molecular process is essential to the reduction of neuronal injuries and is associated with improved functional outcomes and recovery of the patients admitted to the intensive care unit...
December 2018: Journal of Pharmacopuncture
Hye In Jeong, Kyeong Han Kim, Yong Taek Oh, Yoo Min Choi, Beom Yong Song, Jong Uk Kim, Tae-Han Yook
Objectives: The aim of this study was to analyze case reports on and to study Korean medicine treatments of facial palsy. Methods: Studies published after 2000 were selected by searching for the terms "facial palsy" and "Guanwasa" in four databases and case reports using Korean medicine moderating variables were extracted by two individual researchers. Results: The House Brackmann (H-B) Scale (23 times, 65.7%), and Yanagihara Grading Scale (Y-system) (22 times, 62...
December 2018: Journal of Pharmacopuncture
Yean Chun Loh, Chu Shan Tan, Mun Fei Yam, Chuan Wei Oo, Wan Maznah Wan Omar
Objectives: There is an increasing number of complex diseases that are progressively more difficult to be controlled using the conventional "single compound, single target" approach as demonstrated in our current modern drug development. TCM might be the new cornerstone of treatment alternative when the current treatment option is no longer as effective or that we have exhausted it as an option. Orthogonal stimulus-response compatibility group study is one of the most frequently employed formulas to produce optimal herbal combination for treatment of multi-syndromic diseases...
September 2018: Journal of Pharmacopuncture
Bo-Young Jung, Kyeong Han Kim, Song-Yi Kim, Hyun-Kyung Sung, Jeong-Su Park, Ho-Yeon Go, Jang-Kyung Park
Objectives: The study was to survey use of electronic medical records in subjects of Korean medicine doctors working for Korean medicine organizations and to contemplate ways to develop utilization of electronic medical records. Methods: On August 2017, it conducted online self-reported survey on subjects of Korean medicine doctors at Korean hospitals and clinics who agreed to participate in the study. A total 40 doctors in hospital and 279 doctors in clinic were included...
September 2018: Journal of Pharmacopuncture
Zeinab Moshfeghy, Khadegeh Asadi, Marzieh Akbarzadeh, Atefeh Zare, Tahereh Poordast, Masoumeh Emamghoreishi, Fatemeh S Najib, Mehrab Sayadi
Objectives: Vaginal Candidiasis with an approximate prevalence of 30% is the second cause of vaginal infections. Antifungal azole is the first treatment for Vaginal Candidiasis ; however, some side effects have been reported for this chemical medicine. Based on the antifungal activity of Inner Stratum of Quercus Brantii ( Q. Brantii ), the aim of our study was to compare the effects of vaginal douche of Q. Brantii extract and clotrimazole on vaginal candidiasis symptoms before and after the treatments, in women...
September 2018: Journal of Pharmacopuncture
Khadijeh Jamialahmadi, Sofia Salari, Nafiseh Sadat Alamolhodaei, Amir Avan, Leila Gholami, Gholamreza Karimi
Objectives: Auraptene, a natural citrus coumarin, found in plants of Rutaceae and Apiaceae families. In this study, we investigated the effects of auraptene on tumor migration, invasion and matrix metalloproteinase (MMP)-2 and -9 enzymes activity. Methods: The effects of auraptene on the viability of A2780 and Hela cell lines was evaluated by MTT assay. Wound healing migration assay and Boyden chamber assay were determined the effect of auraptene on migration and cell invasion, respectively...
September 2018: Journal of Pharmacopuncture
Kobra Shirani, Hassan Badie Bostan, Ashkan Baroti, Mohammad Hassanzadeh, Zahra Khashyarmanesh, Hamideh Moalemzadeh Haghighi, Gholamreza Karimi
Objectives: Ma-al-shaeer is a popular beverage in Islamic countries. The aim of this study was to determine the concentrations of methanol and ethanol in most consumed brands of Ma-al-shaeer in Iran. Methods: Eighty-one Ma-al-shaeer samples which commonly used in Iran were provided. Methanol and ethanol contents were determined by gas chromatography with flame ionization detector. Results: The mean methanol concentrations in Iranian and foreign brands was 129...
September 2018: Journal of Pharmacopuncture
Maryam Mahmoudabady, Faezeh Sadat Talebian, Narges Amel Zabihi, Seyed Abdolrahim Rezaee, Saeed Niazmand
Objectives: Myocardial reperfusion is the only logical cure for ischemic heart disease. However, ischemic-reperfusion (I/R) injury is one of the underlying factors facilitating and accelerating the apoptosis in the myocardium. This study set to investigate the impact of Teucrium polium (TP) hydro-alcoholic extract on I/R induced apoptosis in the isolated rat heart. Methods: Isolated rat hearts were classified into six groups. The control samples were subjected to 80 min of perfusion with Krebs-Henseleit bicarbonate (KHB) buffer; in control-ischemia group, after primary perfusion (20 min) the hearts were exposed to global ischemia (20 min) and reperfusion (40 min)...
September 2018: Journal of Pharmacopuncture
Seungah Jun, Jung Hee Lee, Han Mi Gong, Seong Hun Choi, Min Hwang Bo, Mi Suk Kang, Geon-Mok Lee, Hyun-Jong Lee, Jae Soo Kim
Objectives: We investigated the efficacy and safety of miniscalpel acupuncture (MA) for knee osteoarthritis (KOA) in an assessor-blinded randomized controlled pilot trial; this would provide information for a large-scale randomized controlled trial. Methods: Participants (n = 24) were recruited and randomly allocated to the MA group (experimental) or acupuncture group (control). The MA group received treatment once a week for 3 weeks (total of 3 treatments), while the acupuncture group received treatment two times per week for 3 weeks (total of 6 treatments)...
September 2018: Journal of Pharmacopuncture
Azin Niazi, Vafa Baradaran Rahimi, Sina Soheili-Far, Nafiseh Askari, Pouria Rahmanian-Devin, Zahra Sanei-Far, Amirhossein Sahebkar, Hassan Rakhshandeh, Vahid Reza Askari
Averagely 80% to 90% of breastfeeding women experience the nipple pain and fissures. The important factor for successful breastfeeding is to treat this problem. This study has done as a review with the aim of analysis of the clinical trials in the field of the prevention and treatment of the nipple fissures and pain due to the importance of breastfeeding. For this purpose, the key words of sore, nipples, fissure, trauma, wound, prevention, treatment, therapeutics, therapy, clinical trial, breastfeeding and their Persian synonyms and all of their possible combinations were searched in the national databases: SID and Iran Medex and Magiran, and in the international databases: PubMed, Scopus, Medline, Science direct by May 2017...
September 2018: Journal of Pharmacopuncture
F Bosco, S Cidin, F Maceri, M Ghilli, M Roncella, L De Simone
This study investigates the effect of a combination of homeopathic medicine and electro-acupuncture in two patients with breast cancer and severe liver disease who could not receive standard anaesthesia therapy due to liver problems. Specifically, measurable and quantifiable parameters were used to evaluate whether an integrated approach-consisting of electro-acupuncture and a homeopathic medicine diluted above Avogadro's limit (that is, above a potency of 12CH) during the pre-surgical, surgical and post-surgical phases--can improve general well-being of a patient undergoing breast cancer surgery...
June 2018: Journal of Pharmacopuncture
Muhack Yang, Jongwon Jang, Eunhye Cha, Byungsoo Ahn, Younghee Bang, Beomyong Song, Jiyong Shin, Chankeun Ahn, Deokho Kim, Sungchul Kim
Objective: The purpose of this study was to investigate the clinical effects of BU pharmacopuncture therapy consisting of bear's gall(fel ursi) and ox bezoar(bovis calculus) on acute lumbar sprain. Methods: 12 patients diagnosed as acute lumbar sprain in 6 designated local Korean medicine clinics from October 2017 to February 2018 were treated by BU pharmacopuncture. Several acupoints in abdomen and lumbar region were selected by clinicians at their own discretion...
June 2018: Journal of Pharmacopuncture
Ui Joung Youn, Bon-Seok Gu, Kyung Hee Kim, Chulgyu Ha, In Chan Jung
Contents of compounds in Rehmanniae Radix change depending on the number of steaming and drying and the drying method. In this study, as an impregnation method for dried Rehmanniae Radix, takju impregnation and cheongju impregnation were carried out and steaming and drying were repeated for 9 times. The changes of 5-HMF and catalpol contents were analyzed according to the number of repetition times to investigate which stage of steaming and drying is preferable. Also, total nitrogen, crude fat, ash, and crude fiber were measured to analyze changes in general components...
June 2018: Journal of Pharmacopuncture
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