Forensic Science Review

Cheiloscopic examinations have long been conducted, and many scientists have reported the usefulness of cheiloscopy for personal identification with a characteristic and individual pattern of furrows on the vermilion lip. For almost 40 years, research conducted in Poland has determined the patterns of these furrows and the separation and development of their individual features. This was the basis for forming expert opinions and presenting them in court as evidence. In Poland, cheiloscopic expertise is performed and the results of precise procedures that are accredited and assessed serve as evidence...

Advocates and researchers have made many recommendations for forensic science improvement in the United States. These proposals are often motivated by wrongful convictions related to false or misleading forensic evidence. In many cases, the connection between the proposals and the actual experience of wrongful convictions has not been well defined. Further, recommendations may not have been realizable given the structure of the criminal justice system in the United States and the practical realities of forensic science laboratories...

Historical events leading to the development of the first handheld instrument for breath alcohol analysis using an electrochemical sensor are reviewed. The first prototype instrument, known as the Alcolmeter Pocket Model, became available in 1972 and weighed only 180 g and was about the size of a cellphone. By the mid-1970s, the Alcolmeter instrument was used by police forces in several countries as a preliminary roadside test of driver sobriety. Positive results in a roadside breath test were considered sufficient evidence to arrest a suspect for further evaluation and testing...

Forensic anthropologists are traditionally interested in facial approximations and reconstruction of physiognomies of individuals from past populations and creation of lifelike features onto unknown skulls retrieved from forensic or bioarchaeological contexts. Present review article examines the significance of facial soft-tissue thickness (FSTT) in craniofacial reconstruction by revisiting the studies published in the recent past decade (2010-21). The searches for published articles mentioning the FSTT and related topics over these years were performed using the following search engines: PubMed, ScienceDirect, Web of Science, and Scopus...

Drug usage data in a community has traditionally been obtained through population surveys, records from law enforcement activities related to drug-related crime, drug treatment centers, prison data, and hospital records. Wastewater-based epidemiology has gained traction in the last 10 years as a formidable complimentary tool to monitor, track, and estimate community consumption of both illicit and therapeutic drugs within a community. In wastewater-based epidemiology, targeted biomarkers (parent drug and/or metabolite) of illicit and therapeutic drugs are quantified in wastewater and back-calculated to community consumption...

The COVID-19 pandemic has affected millions of people around the world either directly or indirectly. Deaths have been attributed to COVID-19 as the underlying cause of death or as a contributing cause of death. It is estimated that millions of excess deaths were associated with the COVID-19 pandemic in 2020 and 2021. The importance of a clinical autopsy on COVID-19 corpses lies in understanding the pathogenesis of the disease better. Moreover, a forensic autopsy may be performed on a COVID-19-infected corpse when indicated for medico-legal purposes...

Although much is known about Δ9-tetrahydrocannabinol and its inactive open ring isomer, cannabidiol, far less is known about the effects, metabolism, and pharmacodynamics of Δ9-tetrahydrocannabinol's double-bond isomer, Δ8-tetrahydrocannabinol. With the passage of the so-called United States "Farm Bill," which was made law in order to allow legal hemp cultivation in the United States, more needs to be known about the effects of Δ8-tetrahydrocannabinol, a double-bond isomer of Δ9-tetrahydrocannabinol, and cannabidiol (CBD), which is an open-ring isomer of Δ8-tetrahydrocannabinol...

This article reviews how the Nordic countries of Denmark, Finland, Norway, and Sweden enforce their legislation pertaining to driving under the influence of alcohol and/or other impairing drugs. The evidence necessary for a successful prosecution of traffic offenders has undergone radical changes over the past 50 years. The once widely used clinical tests of impairment are no longer a major element of the prosecution case and a physician is more seldom required to examine apprehended drivers and document any clinical signs and symptoms of alcohol and/or drug influence...

The unique hard and resilient nature of human teeth makes them useful for various forensic odontological examinations. Structural alterations, cultural modifications, pathological variations, and restorative material make them excellent forensic indicators about biological identity of the unknown deceased or living individuals. Variations in the anatomical details of teeth may be imprinted by defective dental development, traumatic damages, pathologies, and nonmasticatory or weaponry use of teeth during an individual's lifetime...

The US opioid crisis came in three waves - prescription opioids, heroin, and illicitly manufactured fentanyls - Centers for Disease Control and Prevention Centers for Disease Control and Prevention resulting in the deaths of nearly 500,000 people from 1996 to 2019. In 2009, drug overdose deaths exceeded those involving automobiles. Opioid overdose deaths contributed to the decrease in life expectancy for Americans from 78.8 to 78.5 during 2014 to 2017. The overprescribing of a schedule II prescription opioid was escalated by pharmaceutical companies promoting a growing belief that pain was an undertreated condition...

Digital forensics (DF) is becoming one of the most prestigious research areas in computer science due to its inherent nature of providing a means to acquire, examine, analyze, and report evidence to be used in legal processes. To successfully perform it, novel techniques, approaches, and tools have been proposed, experimented on, and evaluated by researchers. However, the experimentation process is not a trivial task in this area as substantial evidence is not accepted in court. Therefore, the experimentation process has to be improved in DF, especially its documentation and data sharing to enable its reproducibility...

Over the last few decades, DNA evidence has become a very powerful tool in forensics, but it also has its limitations. DNA, being a very fragile molecule, can be easily damaged and contaminated. It can be very challenging to find enough DNA in an investigation to really make a breakthrough in certain types of evidence samples. For instance, about half of all rape kits do not yield sufficient genetic information to determine the perpetrator's DNA profile. This is where proteomics, the modern concept of protein analysis, steps in...

Methanol has a very simple chemical structure (CH3OH) considering its potential health hazard, including the many poisoning deaths after ingestion. In countries where authentic alcoholic beverages are expensive, restricted, or banned for religious or other reasons, some people resort to purchasing alcoholic drinks made illegally. These clandestine sources of "booze" often contain high concentrations of methanol, added by the perpetrators to enhance potency and increase profits. Although an effective medical treatment for methanol poisoning exists, because most such incidents occur in socially deprived parts of the world, the hospital emergency facilities are scarce and/or inadequate...

Pesticides are chemical or biological agents used to repel or kill pests. Pesticides are potent and lethal toxic substances that are also being infamously used for homicidal purposes due to their easy availability and rapid action. In this review, we look at 21 articles related to homicidal pesticide poisoning in the literature with an emphasis on fatal doses, routes of administration, and profiles of victims and perpetrators. Organophosphates and rodenticides were the most commonly used classes of pesticides, and ingestion was the most common route of administration; however, other modes of administration, such as through intraperitoneal injection, were also reported...

Heinous crimes and brutalities have decimated humanity throughout human history. In modern times, forensic anthropologists have helped to reconstruct the nature and mechanism, intent and purpose, manner, and circumstances of various inhumane instances of genocides and violent crimes. Anthropologists endeavor to bring closure and comfort to bereaved families by disseminating information about the location, exhumation, and identification of the remains of victims. The methodological armamentarium and scope of forensic anthropology have developed much beyond the realms of the traditional biological profiling casework to the scenarios of humanitarian concerns...

Historically, academic forensic science (FS) programs in the US tended to be relatively small and were embedded in a criminal justice, chemistry, or biology department. Then, in the early 2000s, interest in FS surged, many colleges and universities responded to student demand by adding FS degrees to their curriculums. The search for forensic science programs in the US was done online, using the American Academy of Forensic Sciences' Forensic Science Education Program Accreditation Commission (FEPAC) list of accredited programs, the CollegeSource® Online Google search, Universities...

Sudden infant death syndrome (SIDS) is a poorly understood disorder, and its pathophysiology and risk factors remain unclear. Research in the area is the key to combating the pervasive prevalence of this fatal disorder. We sought to identify the top 50 articles concerning SIDS and study their bibliometric characteristics to gain an insight into the research trends in this area. Using the Scopus database, two independent reviewers conducted a literature search using a prespecified search string. Results were arranged according to the citation count, and the top 50 relevant articles were selected...

The challenge of profiling spermatozoa from samples containing a mixture of male and female cells has been extensively discussed within the forensic community. Various techniques have been developed for the analysis of sexual assault evidence with the aim to generate a single-source male DNA profile. Multiple methods practiced for the isolation of the male component are discussed in this review, with a focus on differential extraction. Benefits of alterations that have been made to the original differential method to increase the efficiency are highlighted...

This review focuses on the role of motor vehicles in the prevention of alcohol-related fatalities in the United States. Since alcohol significantly affects brain function, it is natural to make drivers the prime targets for impaired-driving-prevention programs. However, the prevalence, design, ease of operation, and safety features of motor vehicles, as well as state regulations of their operation, have an important influence on crash occurrences, particularly those involving alcohol. This review begins with a discussion of why the automobile became the central technological device in the alcohol-related fatality problem and then moves on to an overview of motor vehicle safety programs that have impacted impaired driving...

Advancements in DNA sequencing technologies are occurring at a rapid rate. Various platforms have proven useful in all aspects of health and science research, from molecular diagnostics in cancer research to spore identification in bioterrorism. In the field of forensics, one particular single-molecule sequencing platform shows promise for becoming a viable solution for small to midsize forensic laboratories. Oxford Nanopore Technologies (ONT) has developed a portable, nanopore-based sequencing instrument that has already been utilized for on-site identification of Zika and Ebola viruses, full genome sequencing, evaluation of DNA and RNA base modifications, and enrichment-free mitochondrial DNA analysis...