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Infectious Diseases

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https://read.qxmd.com/read/30776943/evaluation-of-laboratory-diagnostic-approaches-for-tuberculous-pleurisy
#1
Xiao-Chun Shi, Yu-Ting Tan, Li-Fan Zhang, Yue-Qiu Zhang, Xiao-Qing Liu
No abstract text is available yet for this article.
February 19, 2019: Infectious Diseases
https://read.qxmd.com/read/30776933/ensuring-access-to-access-antibiotics-an-imminent-consideration-for-sustainable-antimicrobial-stewardship-in-the-developing-world
#2
Ashish Kumar Kakkar, Nusrat Shafiq, Samir Malhotra
No abstract text is available yet for this article.
February 19, 2019: Infectious Diseases
https://read.qxmd.com/read/30776934/effect-of-rifampicin-colistin-combination-against-xdr-acinetobacter-baumannii-harbouring-bla-oxa-23-like-gene-and-showed-reduced-susceptibility-to-colistin-at-cairo-university-hospital-cairo-egypt
#3
Doaa Ghaith, Reem Hassan, Mohamed Ez El-Din Dawoud, Mohamed Eweis, Reem Metwally, Mai Zafer
No abstract text is available yet for this article.
February 18, 2019: Infectious Diseases
https://read.qxmd.com/read/30773087/towards-ending-tb-civil-community-engagement-in-a-rural-area-of-senegal-results-challenges-and-future-proposal
#4
Niccolò Riccardi, Riccardo Alagna, Ilaria Motta, Maurizio Ferrarese, Paola Castellotti, Laura Ambra Nicolini, Mama Moussa Diaw, Mamoudou Ndiaye, Daniela Cirillo, Luigi Codecasa, Giorgio Besozzi
No abstract text is available yet for this article.
February 18, 2019: Infectious Diseases
https://read.qxmd.com/read/30773084/risk-factors-for-pneumocystis-pneumonia-onset-in-hiv-negative-patients-treated-with-high-dose-systemic-corticosteroids
#5
Takemasa Matsumoto, Masaki Fujita, Ryousuke Hirano, Tomoya Sasaki, Kentaro Watanabe
No abstract text is available yet for this article.
February 18, 2019: Infectious Diseases
https://read.qxmd.com/read/30773082/a-review-of-the-immunopathogenesis-of-brucellosis
#6
Omolbanin Amjadi, Alireza Rafiei, Masoud Mardani, Parisa Zafari, Ahmadreza Zarifian
Brucellosis, caused by the intracellular pathogens Brucella, is one of the major zoonotic infections. Considering the economic burden, its prevalence has been a health concern especially in endemic regions. Brucella is able to survive and replicate within host cells by expressing different virulence factors and using various strategies to avoid the host's immune response. This leads to progression of the disease from an acute phase to chronic brucellosis. Exploration of genetic variations has confirmed the expected influence of gene polymorphisms on susceptibility and resistance to brucellosis of humans...
February 18, 2019: Infectious Diseases
https://read.qxmd.com/read/30773081/comparison-of-elisa-and-pcr-of-the-18s-rrna-gene-for-detection-of-human-strongyloidiasis-using-serum-sample
#7
Mostafa Javanian, Tahmineh Gorgani-Firouzjaee, Narges Kalantrai
BACKGROUND: Strongyloides stercoralis infection is a neglected tropical disease with global distribution which is fatal in immunosuppressed patients. This study aimed to determine the prevalence of strongyloidiasis in immunocompromised individuals and cases with infectious diseases, as well as comparing ELISA and conventional PCR with coprological examination, in the central parts of Mazandaran province, northern Iran. METHODS: A single serum and a fresh stool samples were obtained from 272 and 220 patients, respectively...
February 18, 2019: Infectious Diseases
https://read.qxmd.com/read/30773080/a-clinical-pharmacist-survey-of-prophylactic-strategies-used-to-prevent-adverse-events-of-lipid-associated-formulations-of-amphotericin-b
#8
Daniel B Chastain, Rachele L Giles, Christopher M Bland, Carlos Franco-Paredes, Andrés F Henao-Martínez, Henry N Young
No abstract text is available yet for this article.
February 18, 2019: Infectious Diseases
https://read.qxmd.com/read/30760088/a-combination-of-naso-and-oropharyngeal-swabs-improves-the-diagnostic-yield-of-respiratory-viruses-in-adult-emergency-department-patients
#9
Peter Ek, Blenda Böttiger, Disa Dahlman, Karin B Hansen, Mattias Nyman, Anna C Nilsson
BACKGROUND: Along with the current development of molecular diagnostic methods of respiratory viruses, the bedside patient sampling techniques need to be evaluated. We here asked the question whether the addition of an oropharynx swab to the traditional nasopharynx swab might improve the diagnostic yield of multiplex PCR analysis. Ct values from the two sampling sites were compared as well as patient tolerability. METHODS: In an emergency department in Malmö, Sweden, 98 adult patients with respiratory disease were sampled both from the nasopharynx and oropharynx for virus diagnostics by PCR...
February 14, 2019: Infectious Diseases
https://read.qxmd.com/read/30760062/successful-cure-of-daptomycin-non-susceptible-vancomycin-intermediate-staphylococcus-aureus-prosthetic-aortic-valve-endocarditis-directed-by-synergistic-in-vitro-time-kill-study
#10
Zarchi E Sumon, Charles S Berenson, John A Sellick, Zackery P Bulman, Brian T Tsuji, Kari A Mergenhagen
Infectious complications following surgical valve replacements are extremely difficult to treat, often requiring prolonged antimicrobials therapy with or without surgery. Vancomycin-intermediate Staphylococcus aureus is an infrequent pathogen, with an estimated prevalence of less than 0.3%, but presents even greater challenges. We report a case of successful cure of daptomycin-non-susceptible and vancomycin-intermediate Staphylococcus aureus prosthetic valve endocarditis using an eight-week course of combination antimicrobial therapy...
February 14, 2019: Infectious Diseases
https://read.qxmd.com/read/30730248/rapid-micro-organism-identification-from-blood-and-enrichment-fluid-cultures-using-maldi-tof-mass-spectrometry-following-abbreviated-incubation-on-chocolate-agar-plates-in-a-high-throughput-regional-microbiology-laboratory
#11
Rusheng Chew, Ohide Otome, Owen Harris, Aaron Walton, Darren Hewson, Michael Luppino, Raquel U Cowan
No abstract text is available yet for this article.
February 7, 2019: Infectious Diseases
https://read.qxmd.com/read/30729878/preemptive-isolation-and-active-surveillance-in-the-prevention-and-control-of-nosocomial-infection-reduce-the-incidence-of-carbapenem-resistant-enterobacteriaceae
#12
Qiqiang Liang, Chengmin Yan, Zhijiang Xu, Man Huang
No abstract text is available yet for this article.
February 7, 2019: Infectious Diseases
https://read.qxmd.com/read/30729875/an-update-on-the-antimicrobial-susceptibility-and-molecular-epidemiology-of-stenotrophomonas-maltophilia-in-bulgaria-a-5-year-study-2011-2016
#13
Tanya Strateva, Angelina Trifonova, Encho Savov, Svetoslav Dimov, Ivan Mitov
No abstract text is available yet for this article.
February 7, 2019: Infectious Diseases
https://read.qxmd.com/read/30729868/long-term-improvement-in-renal-bone-lipid-parameters-and-cd4-cd8-ratio-in-hiv-infected-patients-switching-to-a-dual-therapy-with-lamivudine-plus-boosted-darunavir
#14
María Fontecha, Marta Monsalvo, Miguel A Rodriguez-Sagrado, María J Vivancos, Ana Moreno, José L Casado
BACKGROUND: Dual therapies have been tested in selected patients, but there is no evidence for its advantages in clinical practice. The aim of this study was to evaluate in the clinical setting the long-term outcomes and the impacts on comorbidities of a dual therapy based on lamivudine plus darunavir boosted with ritonavir (DRV/r). METHODS: A prospective cohort study of 106 patients who were switched to this dual regimen from April 2014 to December 2017 because of renal and bone toxicity, intolerance, or physician's decision was conducted...
February 7, 2019: Infectious Diseases
https://read.qxmd.com/read/30729846/clinical-outcome-of-patients-with-clostridium-difficile-infection-single-center-study
#15
Bednarska Agnieszka, Paciorek Marcin, Podlasin Beata, Pihowicz Andrzej, Sosińska-Bryła Iwona, Bursa Dominik, Antosiewicz Mateusz, Feliciak Marcin, Horban Andrzej
No abstract text is available yet for this article.
February 7, 2019: Infectious Diseases
https://read.qxmd.com/read/30729841/is-hiv-1-viraemia-below-20-copies-ml-in-antiretroviral-treated-patients-associated-with-virologic-outcome
#16
Myriam den Oudsten, Jeroen van Kampen, Bart Rijnders, David van de Vijver, Marchina van der Ende
BACKGROUND: We aimed to investigate whether very low-level HIV-1 viraemia (VLLV) <20 copies/mL in HIV-1-infected patients on antiretroviral therapy (ART) whose VL was <20 copies/mL, was associated with a subsequent VL > 20 copies/mL. METHODS: VLLV was defined as VL <20 copies/mL and positive HIV-1-PCR. We compared patients with positive and negative HIV-1-PCRs <20 copies/mL at two time points, T0 and T1, after 21st of January 2016. Factors associated with a VLLV and subsequent VL >20 copies/mL were identified by logistic regression models...
February 7, 2019: Infectious Diseases
https://read.qxmd.com/read/30729840/evaluation-of-quickfish-and-maldi-sepsityper-for-identification-of-bacteria-in-bloodstream-infection
#17
Helena Enroth, Karolina Retz, Sofie Andersson, Carl Andersson, Kristina Svensson, Lars Ljungström, Diana Tilevik, Anna-Karin Pernestig
BACKGROUND: Early detection of bacteria and their antibiotic susceptibility patterns are critical to guide therapeutic decision-making for optimal care of septic patients. The current gold standard, blood culturing followed by subculture on agar plates for subsequent identification, is too slow leading to excessive use of broad-spectrum antibiotic with harmful consequences for the patient and, in the long run, the public health. The aim of the present study was to assess the performance of two commercial assays, QuickFISH® (OpGen) and Maldi Sepsityper™ (Bruker Daltonics) for early and accurate identification of microorganisms directly from positive blood cultures...
February 7, 2019: Infectious Diseases
https://read.qxmd.com/read/30729831/surgery-is-safe-and-effective-when-indicated-in-the-acute-phase-of-hematogenous-pyogenic-vertebral-osteomyelitis
#18
Etienne Canouï, Virginie Zarrouk, Florence Canouï-Poitrine, Ugo Desmoulin, Véronique Leflon, Wassim Allaham, Victoire de Lastours, Pierre Guigui, Bruno Fantin
BACKGROUND: The overall benefit of surgical management in the acute phase of hematogenous pyogenic vertebral osteomyelitis remains difficult to evaluate because of the balance between potential functional benefit versus complications of surgery. METHODS: Between 2000 and 2013, in a tertiary care hospital, we analyzed a cohort of patients with hematogenous pyogenic vertebral osteomyelitis treated surgically and compared them to those treated medically. Neurologic deficit (using the ASIA impairment scale) and pain (using the analgesic level required) 4 months later, recurrences and infection-related deaths 12 months later were evaluated...
February 7, 2019: Infectious Diseases
https://read.qxmd.com/read/30689510/evaluation-of-the-15-and-24-loci-miru-vntr-genotyping-tools-with-spoligotyping-in-the-identification-of-mycobacterium-tuberculosis-strains-and-their-genetic-diversity-in-molecular-epidemiology-studies
#19
Dulanthi Weerasekera, Harshani Pathirane, Dushantha Madegedara, Neranjan Dissanayake, Vasanthi Thevanesam, Dhammika Nayoma Magana-Arachchi
BACKGROUND: The transmission dynamics of Mycobacterium tuberculosis (Mtb) using various genotyping tools has been studied globally and a particular tool for genotyping Mtb is the mycobacterial interspersed repetitive units-variable number tandem repeats (MIRU-VNTR). Tuberculosis (TB) remains an important public health problem worldwide and Sri Lanka being a country of tourist destination; because of major development projects undergoing, it has a high proportion of tourists and immigrants from Asia and Europe that are characterized with highest TB incidences and drug-resistant clinical isolates...
January 28, 2019: Infectious Diseases
https://read.qxmd.com/read/30676833/high-nuc-dna-load-in-whole-blood-is-associated-with-sepsis-mortality-and-immune-dysregulation-in-staphylococcus-aureus-bacteraemia
#20
Ingrid Ziegler, Sara Cajander, Gunlög Rasmussen, Theresa Ennefors, Paula Mölling, Kristoffer Strålin
BACKGROUND: Staphylococcus aureus bacteraemia is a disease with varying presentation, ranging from uncomplicated to life-threatening infections. In S. aureus bacteraemia, a high load of bacterial DNA in blood has been linked to mortality. We hypothesized that a high DNA load would also be linked to the presence of sepsis, and to high C-reactive protein (CRP) and lymphopaenia, indicating inflammation and immunosuppression. METHODS: Twenty-seven patients with culture-proven S...
January 24, 2019: Infectious Diseases
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