Przemyslaw E Cieslak, Sylwia Drabik, Anna Gugula, Aleksandra Trenk, Martyna Gorkowska, Kinga Przybylska, Lukasz Szumiec, Grzegorz Kreiner, Jan Rodriguez Parkitna, Anna Blasiak
The motor cortex comprises the primary descending circuits for flexible control of voluntary movements and is critically involved in motor skill learning. Motor skill learning is impaired in patients with Parkinson's disease, but the precise mechanisms of motor control and skill learning are still not well understood. Here we have used transgenic mice, electrophysiology, in situ hybridization and neural tract-tracing methods to target genetically defined cell types expressing D1 and D2 dopamine receptors in the motor cortex...
February 29, 2024: ENeuro