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Lancet HIV

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https://read.qxmd.com/read/30777727/incidence-of-a-first-venous-thrombotic-event-in-people-with-hiv-in-the-netherlands-a-retrospective-cohort-study
#1
Jaime F Borjas Howard, Casper Rokx, Colette Smit, Ferdinand W N M Wit, Elise D Pieterman, Karina Meijer, Bart Rijnders, Wouter F W Bierman, Y I G Vladimir Tichelaar
BACKGROUND: The risk of venous thrombotic events is elevated in people with HIV, but overall risk estimates and estimates specific to immune status and antiretroviral medication remain i mprecise. In this study, we aimed to estimate these parameters in a large cohort of people with HIV in the Netherlands. METHODS: In this retrospective cohort study, we used the Dutch ATHENA cohort to estimate crude, age and sex standardised, and risk period-specific incidences of a first venous thrombotic event in people with HIV aged 18 years or older attending 12 HIV treatment centres in the Netherlands...
February 15, 2019: Lancet HIV
https://read.qxmd.com/read/30777726/strategies-for-engaging-men-in-hiv-services
#2
REVIEW
Christopher J Colvin
The importance of men in the global HIV response is increasingly recognised. In most settings, men are less engaged in HIV services and have worse health outcomes than women. The multiple gender, social, economic, political, and institutional factors behind these patterns are well documented. More recently, researchers have been reporting evidence on strategies aimed at improving the engagement of men in HIV services. Several promising approaches exist, including community-based outreach programmes, gender-transformative interventions to shift gender norms and practices, and the development of more responsive, male-friendly health services...
February 15, 2019: Lancet HIV
https://read.qxmd.com/read/30777725/is-hiv-a-provoking-factor-for-venous-thrombotic-events
#3
Line D Rasmussen, Niels Obel
No abstract text is available yet for this article.
February 15, 2019: Lancet HIV
https://read.qxmd.com/read/30772420/providers-should-discuss-u-u-with-all-patients-living-with-hiv
#4
Sarah K Calabrese, Kenneth H Mayer
No abstract text is available yet for this article.
February 13, 2019: Lancet HIV
https://read.qxmd.com/read/30772419/putting-participants-at-the-centre-of-hiv-cure-research
#5
Karine Dubé, Liz Barr, David Palm, Brandon Brown, Jeff Taylor
No abstract text is available yet for this article.
February 13, 2019: Lancet HIV
https://read.qxmd.com/read/30770325/should-efavirenz-be-used-in-children-and-if-so-how
#6
Mark F Cotton, Barbara Laughton, Helena Rabie
No abstract text is available yet for this article.
February 12, 2019: Lancet HIV
https://read.qxmd.com/read/30770324/neuropsychiatric-symptoms-in-tanzanian-hiv-infected-children-receiving-long-term-efavirenz-treatment-a-multicentre-cross-sectional-observational-study
#7
Lisa Van de Wijer, Deborah N Mchaile, Quirijn de Mast, Blandina T Mmbaga, Nanda N J Rommelse, Ashanti Duinmaijer, André J A M van der Ven, Arnt F A Schellekens, Grace D Kinabo
BACKGROUND: Efavirenz is commonly prescribed for children with HIV infection, yet little is known about risks of neuropsychiatric side-effects. We aimed to compare competence (social involvement, activities, and school performance) and psychopathology (internalising and externalising problems), cognitive performance (intelligence and working memory), and adherence in Tanzanian children on an efavirenz-based versus a non-efavirenz-based regimen. METHODS: In this multicentre, cross-sectional, observational study, we included consecutive children (aged 6-12 years) with HIV infection, on combination antiretroviral therapy (cART) for at least 6 months, and with viral loads of less than 1000 copies per mL from HIV care clinics of three primary health facilities and three referral hospitals in Moshi, Kilimanjaro, Tanzania...
February 12, 2019: Lancet HIV
https://read.qxmd.com/read/30765314/genetic-clusters-and-transmission-in-transgender-women
#8
Tiago Gräf, Joshua T Herbeck
No abstract text is available yet for this article.
February 11, 2019: Lancet HIV
https://read.qxmd.com/read/30765313/hiv-transmission-networks-among-transgender-women-in-los-angeles-county-ca-usa-a-phylogenetic-analysis-of-surveillance-data
#9
Manon Ragonnet-Cronin, Yunyin W Hu, Sheldon R Morris, Zhijuan Sheng, Kathleen Poortinga, Joel O Wertheim
BACKGROUND: Transgender women are among the groups at highest risk for HIV infection, with a prevalence of 27·7% in the USA; and despite this known high risk, undiagnosed infection is common in this population. We set out to identify transgender women and their partners in a molecular transmission network to prioritise public health activities. METHODS: Since 2006, HIV protease and reverse transcriptase gene (pol) sequences from drug resistance testing have been reported to the Los Angeles County Department of Public Health and linked to demographic data, gender, and HIV transmission risk factor data for each case in the enhanced HIV/AIDS Reporting System...
February 11, 2019: Lancet HIV
https://read.qxmd.com/read/30737188/point-of-care-assays-for-early-infant-diagnosis-in-zimbabwe
#10
Sarah J Girdwood, Brooke E Nichols
No abstract text is available yet for this article.
February 5, 2019: Lancet HIV
https://read.qxmd.com/read/30737187/clinical-effect-and-cost-effectiveness-of-incorporation-of-point-of-care-assays-into-early-infant-hiv-diagnosis-programmes-in-zimbabwe-a-modelling-study
#11
Simone C Frank, Jennifer Cohn, Lorna Dunning, Emma Sacks, Rochelle P Walensky, Sushant Mukherjee, Caitlin M Dugdale, Esther Turunga, Kenneth A Freedberg, Andrea L Ciaranello
BACKGROUND: New point-of-care (POC) assays for early infant HIV diagnosis are costlier than conventional total nucleic acid assays, but could increase access to testing, shorten time to results, and expedite initiation of antiretroviral therapy. We aimed to assess the clinical benefits and cost-effectiveness of incorporating these POC assays into early infant diagnosis programmes in Zimbabwe. METHODS: We used the Cost Effectiveness of Preventing AIDS Complications (CEPAC)-Pediatric model to examine the clinical benefits, costs, and cost-effectiveness of replacing conventional assays for early infant HIV diagnosis with POC assays at age 6 weeks in Zimbabwe...
February 5, 2019: Lancet HIV
https://read.qxmd.com/read/30691953/correction-to-lancet-hiv-2018-5-e553-59
#12
(no author information available yet)
No abstract text is available yet for this article.
January 25, 2019: Lancet HIV
https://read.qxmd.com/read/30683626/how-do-we-preserve-health-among-adults-living-with-hiv
#13
Line D Rasmussen, Niels Obel
No abstract text is available yet for this article.
January 22, 2019: Lancet HIV
https://read.qxmd.com/read/30660594/financial-incentives-for-achieving-and-maintaining-viral-suppression-among-hiv-positive-adults-in-uganda-a-randomised-controlled-trial
#14
Harsha Thirumurthy, Alex Ndyabakira, Kara Marson, Devy Emperador, Moses Kamya, Diane Havlir, Dalsone Kwarisiima, Gabriel Chamie
BACKGROUND: Viral suppression among HIV-positive individuals is essential for protecting health and preventing HIV transmission. Financial incentives have shown promise in modifying various health behaviours in low-income countries but few studies have assessed whether they can improve HIV treatment outcomes. We aimed to determine the impact of time-limited financial incentives on viral suppression among HIV-positive adults in rural Uganda. METHODS: We did a randomised controlled trial in four rural Ugandan parishes...
January 16, 2019: Lancet HIV
https://read.qxmd.com/read/30660593/the-effect-of-incentives-on-hiv-research-must-be-studied
#15
Brandon Brown, Jerome T Galea
No abstract text is available yet for this article.
January 16, 2019: Lancet HIV
https://read.qxmd.com/read/30660592/global-prep-roll-out-recommendations-for-programmatic-success
#16
K Rivet Amico, Linda-Gail Bekker
Pre-exposure prophylaxis (PrEP) is being adopted and rolled out in diverse regions, communities, and groups. Although it has been shown to be effective, in some settings PrEP roll-out has lagged, in part due to flawed messaging. Lessons can be learned and principles applied from marketing to highlight the potential pitfalls of current roll-out strategies focused on selective and siloed service provision. After exploration of the way PrEP is promoted in awareness messaging (the sell), marketed to select and often stigmatised groups (the brand), and offered as a special or non-integrated service (product placement), we propose that current strategies can ultimately slow roll-out and contribute to stigma surrounding PrEP use...
January 16, 2019: Lancet HIV
https://read.qxmd.com/read/30584047/community-based-distribution-of-oral-hiv-self-testing-kits-in-zambia-a-cluster-randomised-trial-nested-in-four-hptn-071-popart-intervention-communities
#17
Chama Mulubwa, Bernadette Hensen, Mwelwa M Phiri, Kwame Shanaube, Albertus J Schaap, Sian Floyd, Comfort R Phiri, Chiti Bwalya, Virginia Bond, Musonda Simwinga, Lawrence Mwenge, Sarah Fidler, Richard Hayes, Alwyn Mwinga, Helen Ayles
BACKGROUND: The HPTN 071 (PopART) cluster-randomised trial provided door-to-door HIV testing services to a large proportion of individuals residing in 21 intervention communities in Zambia and South Africa from 2014 to 2017 and reached the UNAIDS first 90 target among women in Zambia, yet gaps remained among men and young adults. This cluster-randomised study nested in the HPTN 071 (PopART) trial sought to increase knowledge of HIV status across all groups by offering the choice of oral HIV self-testing in addition to routine door-to-door HIV testing services...
December 21, 2018: Lancet HIV
https://read.qxmd.com/read/30581027/rehabilitate-unaids-to-reflect-hiv-aids-community-values
#18
EDITORIAL
The Lancet Hiv
No abstract text is available yet for this article.
December 20, 2018: Lancet HIV
https://read.qxmd.com/read/30558843/elimination-of-hiv-transmission-through-novel-and-established-prevention-strategies-among-people-who-inject-drugs
#19
REVIEW
Hudson Reddon, Brandon D L Marshall, M-J Milloy
Despite the effectiveness of existing HIV prevention strategies for people who inject drugs (PWID), uncontrolled outbreaks of HIV among this group are common and occur around the world. In this Review, we summarise recent evidence for novel and established HIV prevention approaches to eliminate HIV transmission among PWID. Effective HIV prevention strategies include mobile needle and syringe programmes, pre-exposure prophylaxis, supervised injection facilities, and, to a lesser extent, some behavioural interventions...
December 14, 2018: Lancet HIV
https://read.qxmd.com/read/30555051/safety-of-elvitegravir-cobicistat-emtricitabine-and-tenofovir-alafenamide-in-hiv-1-infected-adults-with-end-stage-renal-disease-on-chronic-haemodialysis-an-open-label-single-arm-multicentre-phase-3b-trial
#20
Joseph J Eron, Jean-Daniel Lelievre, Robert Kalayjian, Jihad Slim, Anson K Wurapa, Jeffrey L Stephens, Cheryl McDonald, Eric Cua, Aimee Wilkin, Brigitte Schmied, Mehri McKellar, Stephanie Cox, Sophia R Majeed, Shuping Jiang, Andrew Cheng, Moupali Das, Devi SenGupta
BACKGROUND: Current treatment for HIV-infected individuals with renal failure on haemodialysis frequently requires complex regimens with multiple pills. A daily single-tablet regimen of coformulated elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide is approved in Europe, the USA, and in other regions for use in HIV-1-infected individuals with mild-to-moderate chronic kidney disease (creatinine clearance 30-69 mL/min). We aimed to assess the safety, efficacy, and pharmacokinetics of this regimen in HIV-infected adults with end-stage renal disease on chronic haemodialysis...
December 13, 2018: Lancet HIV
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