journal
https://read.qxmd.com/read/38230601/villoglandular-adenocarcinoma-of-the-uterine-cervix-a-case-report
#1
JOURNAL ARTICLE
Soyoung Park, Min Gyoung Pak, Jung-Woo Park
Cervical adenocarcinomas constitute for approximately 10%-20% of all invasive cervical cancers. Villoglandular adenocarcinomas (VGAs) are a rare subtype of cervical adenocarcinoma, representing approximately 5% of all cases of cervical adenocarcinomas. Herein, we report the case of a 49-year-old perimenopausal woman successfully treated for VGA. The patient presented to the hospital with a primary complaint of vaginal discharge persisting for 7 months with worsening symptoms. She had no underlying medical conditions or history of oral contraceptive use...
December 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/38230600/mature-cystic-teratoma-of-the-ovary-transforms-into-squamous-cell-carcinoma-a-case-report
#2
JOURNAL ARTICLE
Chul Hoi Jeong
Mature cystic teratomas (MCTs) are benign ovarian tumors known to undergo malignant transformation in 1%-2% of cases. Most of these cases lead to squamous cell carcinomas (SCC), and the prognosis is often poor, particularly in advanced-stage disease. A 50-year-old postmenopausal woman presented with a large pelvic mass. The patient initially underwent suboptimal primary surgery and was later diagnosed with stage IIIA SCC arising from MCT. Following the first cycle of chemotherapy with carboplatin and paclitaxel, a computed tomography scan showed a rapidly growing large mass in the pelvic cavity after 4 weeks of primary surgery, leading to a second debulking surgery...
December 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/38230599/a-case-report-of-turner-syndrome-diagnosed-at-age-61-years
#3
JOURNAL ARTICLE
Yookyung Jin, Youri Lee, Sung Eun Kim
Here, we describe a case of Turner syndrome first diagnosed at 61 years of age. The patient's chief complaint was general edema. A cardiologist was consulted, who performed echocardiogram and coronary heart computed tomography. Chromosomal analysis yielded inconclusive results for Turner syndrome. The patient's karyotype was 45,X[17]/46,X,psu idic(Y)(q11.23), and she was referred to a gynecologist a time span. The patient was nulliparous with no history of sexual contact. We performed a prophylactic gonadectomy, but no malignancy was detected pathologically...
December 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/38230598/extrauterine-undifferentiated-uterine-sarcoma-arising-from-bladder-endometriosis-in-a-postmenopausal-woman-a-case-report
#4
JOURNAL ARTICLE
Ye Bin Sim, Jin Kyung Baek, Seok Kyo Seo
Endometriosis (EMS) is a rare condition in postmenopausal women. The incidence of transition from EMS to malignancy is as low as 1%, with endometrial stromal tumors (ESTs) occurring at an even lower incidence of 0.7%. Undifferentiated uterine sarcomas (UUSs) are a subtype of ESTs that account for 25% of all ESTs. Extrauterine UUSs are exceptionally rare, with only a few reported cases in the literature. We present the case of a woman who underwent surgery for deep infiltrating EMS and was later diagnosed with UUS, which originated from the bladder after surgical menopause...
December 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/38230597/ovarian-torsion-in-a-postmenopausal-woman-a-case-report-and-review-of-literature
#5
JOURNAL ARTICLE
Poojan Dogra Marwaha, Asmita Kaundal, Bhavna, Nisha Malik, Sushruti Kaushal
No abstract text is available yet for this article.
December 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/38230596/initial-preoperative-hemoglobin-level-affects-the-rate-of-decline-in-anti-m%C3%A3-llerian-hormone-levels-after-laparoscopic-ovarian-cystectomy-in-women-with-ovarian-endometriosis
#6
JOURNAL ARTICLE
Soojin Rhee, Sungwook Chun, Yong Il Ji
OBJECTIVES: To determine the factors affecting the decline in ovarian reserve following laparoscopic ovarian cystectomy (LOC) in women with ovarian endometriosis. METHODS: This retrospective study included 22 women, aged 25-45 years, with regular menstrual cycles who underwent unilateral LOC and were diagnosed with ovarian endometriosis at a university hospital. Blood samples were collected preoperatively and on the third postoperative day to determine the serum anti-Müllerian hormone (AMH) levels for assessment of the decline in ovarian reserve during the early postoperative period...
December 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/38230595/health-seeking-behaviors-and-treatments-received-for-menopause-symptoms-a-questionnaire-survey-among-midlife-women-attending-primary-healthcare-clinics-in-malaysia
#7
JOURNAL ARTICLE
Anusha Manoharan, Megat Muhammad Haris Megat Zainal, Beh Hooi Chin, Koh Wen Ming, Zamzurina Asmuee, Norafini Salamon, Peter Jerampang, Radhiyah Hussin, Nadia Hamimah Kamaludin, Chandrashekhar T Sreeramareddy
OBJECTIVES: This study aimed to assess menopause symptoms, treatment-seeking behaviors, treatments received, and factors associated with seeking consultation from healthcare providers (HCPs). METHODS: Using a self-administered Menopause Quick-6 in the Malay language (MQ6[M]) questionnaire, we surveyed 349 women aged 40-60 years attending primary healthcare clinics in four states in Malaysia for their menopause symptoms. Health-seeking behaviors for menopause symptoms were assessed using questions regarding HCPs consulted and treatments prescribed...
December 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/38230594/comparison-of-the-right-and-left-femur-bone-mineral-densities-in-postmenopausal-women
#8
JOURNAL ARTICLE
Sejin Kim, Yoojin Na, Minji Ko, Jung Yoon Park, Hyonjee Yoon, Jae-Yen Song, Youn-Jee Chung, Inhye Shin, Chaewon Kim, Jung Hyun Park, Mee-Ran Kim
OBJECTIVES: Bone mineral density (BMD) is measured in the hip and posteroanterior spine; moreover, according to the 2019 International Society for Clinical Densitometry guidelines, unilateral hip can be used. This study aimed to determine whether there is a difference between the BMD of both the femurs in postmenopausal women. METHODS: A total of 343 postmenopausal women were enrolled in this study from January 1, 2010, to December 31, 2019 at a single tertiary hospital...
December 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/38230593/skin-rejuvenation-in-women-using-menopausal-hormone-therapy-a-systematic-review-and-meta-analysis
#9
JOURNAL ARTICLE
Laura Pivazyan, Julietta Avetisyan, Maria Loshkareva, Amina Abdurakhmanova
OBJECTIVES: To evaluate the effect of menopausal hormone therapy (MHT) on skin aging in menopausal women. METHODS: Studies were identified by searching PubMed, Cochrane Library, Google Scholar, and ClinicalTrials.gov databases using the key words "hormone replacement therapy" AND "skin" AND "menopausal." Studies that used and compared oral/transdermal MHT with placebo or another type of treatment in menopausal women aged 45-55 years were selected. RESULTS: From 1,526 studies identified, 15 studies comprising 1,589 patients were included in the final analysis...
December 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/38230592/tibolone-and-breast-cancer
#10
REVIEW
Jae Kyung Lee, Hyewon Yun, Heeyon Kim, Bo Hyon Yun, Seok Kyo Seo
Tibolone, a selective tissue estrogenic activity regulator, is a synthetic steroid with distinct pharmacological and clinical characteristics in contrast to conventional menopausal hormone therapy. Tibolone induces estrogenic activity in the brain, vagina, and bone but remains inactive in the endometrium and breast. In particular, several studies have investigated whether tibolone usage increases the risk of breast cancer. This study aims to determine the effects of tibolone on the breast by focusing on the relation between tibolone use and breast cancer...
December 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/38230591/a-recent-review-of-the-management-of-postmenopausal-symptoms-in-breast-cancer-survivors
#11
REVIEW
Chaewon Kim, Yoojin Na, Sanghee Lee, Jung Yoon Park, Youn-Jee Chung, Jaeyen Song, Mee-Ran Kim
The treatment strategy for postmenopausal symptoms resulting from estrogen deficiency in breast cancer survivors receiving endocrine therapy should differ from that in normal women. Several nonhormonal pharmacological therapies can be used to treat vasomotor symptoms. Cognitive-behavioral therapy can help alleviate psychophysiological symptoms, including depression and sleep disorders. Topical vaginal estrogen and moisturizers may aid in treating genitourinary symptoms. Additionally, chronic conditions must be individually managed...
December 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/37691315/combination-of-soy-isoflavones-8-prenylnaringenin-and-melatonin-improves-hot-flashes-and-health-related-quality-of-life-outcomes-in-postmenopausal-women-flavie-study
#12
JOURNAL ARTICLE
Carmela Puchol Estrugo, Miriam Trujillo Rodríguez, Nicolás Mendoza-Ladrón de Guevara, Joaquín Grande Gómez, Francisca Ridocci, Maria Teresa Moro-Martín, Misericordia Guinot, Paula Saz-Leal, Concepción Nieto Magro
OBJECTIVES: This study aims to investigate the effects of a combination of soy isoflavones, 8-prenylnaringenin (8-PN), and melatonin in postmenopausal women suffering from moderate-to-severe hot flashes (HFs). METHODS: A multicenter, prospective, open-label study enrolled 44 postmenopausal women suffering from moderate-to-severe HFs (≥ 5 daily or ≥ 35 weekly) to receive 54.4 mg standardized soy isoflavones (including 24.5 mg genistein and 16.3 mg daidzein), 100 µg 8-PN, and 1 mg melatonin once daily for 12 weeks...
August 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/37691314/association-between-fractures-and-low-muscle-mass-in-korean-menopausal-women-data-from-korean-national-health-and-nutrition-survey-2010-2011
#13
JOURNAL ARTICLE
Yeojin Lee, Songhyeon Je, Hae-Rim Kim, Jae Kyung Lee, Euna Choi, Jin Kyung Baek, Heeyon Kim, Bo Hyon Yun, Seok Kyo Seo
OBJECTIVES: This study used the Korean National Health and Nutrition Examination Survey (KNHANES) to determine the association between fractures and low muscle mass. METHODS: This cross-sectional study used the 2010-2011 KNHANES data. Low muscle mass was defined as (appendicular skeletal muscle mass [kg]/Height² [m²]) < 5.45 kg/m², which is < 2 SD below the sex-specific mean of a young reference group. Patients with T-scores between -1.0 and -2...
August 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/37691313/correlation-of-sarcopenic-obesity-on-various-cardiometabolic-risk-factors-and-fracture-risk-in-mid-aged-korean-women
#14
JOURNAL ARTICLE
Eun Hee Yu, Hyun Joo Lee, Hyeon Jin Kim, In Hye Kim, Jong Kil Joo, Yong Jin Na
OBJECTIVES: This study aimed to investigate the correlation of sarcopenic obesity with various cardiometabolic risk factors and fracture risk in middle-aged Korean women. METHODS: In this cross-sectional study, the medical records of 1,775 women who had visited Pusan National University Hospital for routine health screenings from 2010 to 2016 were reviewed. The patients were divided into four groups as follows: group 1, nonsarcopenic, nonobese (NS-NO); group 2, nonsarcopenic, obese (NS-O); group 3, sarcopenic, nonobese (S-NO); and group 4, sarcopenic, obese (S-O)...
August 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/37691312/body-composition-and-bone-mineral-density-in-postmenopausal-women-with-advanced-knee-osteoarthritis-undergoing-surgical-treatment
#15
JOURNAL ARTICLE
Jung Yoon Park, Youn-Jee Chung, Jae-Yen Song, Chaewon Kim, Haein Lee, Yeiyoon Son, Inhye Shin, Jung Hyun Park, Mee-Ran Kim
OBJECTIVES: This study aimed to demonstrate the bone mineral density (BMD) and body composition in postmenopausal women with knee osteoarthritis (OA) who underwent surgical treatment, such as total knee arthroplasty, osteotomy, or meniscectomy. METHODS: A total of 254 women with OA aged 50 years who underwent surgical treatment were enrolled in this study. We evaluated obesity-related factors, muscle components, and BMD using dual-energy X-ray absorptiometry. RESULTS: No significant differences were noted in the BMD of the hip joint between the symptomatic side of the leg with knee OA and the contralateral side...
August 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/37691311/minireview-a-need-for-an-adequate-diet-program-for-postmenopausal-women-with-obesity-in-the-republic-of-korea
#16
REVIEW
So Hee Park, Bo Dam Kim, Jae Hong Sang, Hae-Hyeog Lee, Tae-Hee Kim
Women undergo various physical changes because of hormonal changes occurring after menopause. Some representative changes caused by the reduction in estrogen levels in these women are dyslipidemia, abnormal lipoprotein levels, obesity, weight gain, and changes in body fat distribution. A characteristic of women approaching menopause is the shift of fat from their hips and thighs to their abdomen. Notably, fat accumulation is common in internal organs, resulting in male-pattern obesity among women approaching menopause; therefore, these women require more exercise therapy than premenopausal women to prevent and treat obesity...
August 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/37160301/vulvar-basal-cell-carcinoma-in-postmenopausal-women-two-case-reports
#17
JOURNAL ARTICLE
Hwa Yeon Choi, Mee Sook Roh, Jung-Woo Park
Basal cell carcinoma (BCC) is a major non-melanoma skin cancer, and its incidence is increasing worldwide. Although the main etiology is sun exposure, BCC may develop in sun-protected areas such as the vulva. The sonic hedgehog signaling pathway mutation may explain the mechanism underlying the occurrence of vulvar BCC. Owing to the rarity of metastases, wide local excision is an appropriate treatment option. Here, we report the cases two postmenopausal women with vulvar BCC who were surgically treated.
April 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/37160300/metabotropic-effect-of-probiotic-supplementation-and-high-intensity-interval-training-in-menopause-induced-metabolic-syndrome-in-rats
#18
JOURNAL ARTICLE
Zeinab Bayat, Arsalan Damirchi, Meysam Hasannejad-Bibalan, Parvin Babaei
OBJECTIVES: This study aimed to investigate the interactive effect of supplementation with a native potential probiotic lactobacillus and 8-week high-intensity interval training (HIIT) on insulin resistance and dyslipidemia in a menopause-induced metabolic syndrome. METHODS: A total of 40 ovariectomized (OVX) Wistar rats were divided into five groups: control (OVX + Vehicle), exercise (EXE) (OVX + Exe), probiotic (Prob) (OVX + Prob), exercise and probiotic (OVX + Exe + Prob), and sham surgery...
April 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/37160299/effect-of-fennel-valerian-extract-on-hot-flashes-and-sleep-disorders-in-postmenopausal-women-a-randomized-trial
#19
JOURNAL ARTICLE
Ensiyeh Jenabi, Salman Khazaei, Soodabeh Aghababaei, Shirin Moradkhani
OBJECTIVES: This study aims to evaluate the effect of a mixture of fennel and valerian extracts on hot flashes and sleep disorders of postmenopausal women in Iran. A randomized trial was conducted. METHODS: A total of 76 postmenopausal women were randomly assigned to either of the two groups: fennel-valerian extract or control. One 500 mg fennel-valerian extract capsule was given twice, daily for 8 weeks. The 500 mg oral placebo capsule (starch) was given the same way...
April 2023: Journal of Menopausal Medicine
https://read.qxmd.com/read/37160298/examining-the-health-related-needs-of-females-during-menopause-a-systematic-review-study
#20
REVIEW
Masoumeh Rostami-Moez, Seyedeh Zahra Masoumi, Marzieh Otogara, Farhad Farahani, Shohreh Alimohammadi, Khodayar Oshvandi
Menopause is one the most crucial stages in a female's life. Identifying the education gaps regarding menopause is important, thus this study aims to explain the health-related needs of females during menopause. Scopus, PubMed, Scientific Information Database, and Web of Science databases were searched for the available observational (cohort, case-control, and cross-sectional), systematic review, meta-analysis, and clinical trial studies (2007-2021) using keywords, such as 'Educational Needs Assessment,' 'Assessment of Healthcare Needs,' 'menopause,' 'climacteric,' 'premenopause,' and 'postmenopause...
April 2023: Journal of Menopausal Medicine
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