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Turkish Journal of Medical Sciences

Erdal Ceylan, Ayşegül Koç, Ahmet Çağkan İnkaya, Serhat Ünal
Background/aim: Widespread use of antiretroviral treatment (ART) has led to decrease in the incidence of HIV/AIDS-related mortality. Besides the availability of ART, medication adherence is essential for treatment success. There is a scarcity of data reported from Turkey regarding ART adherence among people living with HIV/AIDS (PLWHA). Therefore, this study was undertaken to determine medication adherence and related factors among PLWHA in Turkey. Materials and methods: The sample consisted of 158 PLWHA, who were being followed up at Infectious Diseases Outpatient Clinic of Hacettepe University Hospital...
February 11, 2019: Turkish Journal of Medical Sciences
Ayşegül İdil Soylu, Korhan Soylu, Ramazan Aydın, Fatih Uzunkaya, Kerim Aslan, Ahmet Veysel Polat
Background/aim: Materials and methods: A total of 404 female patients above 40 years of age who, within a 6-month period, had undergone thoracic computed tomography and mammography for various reasons were screened retrospectively at our clinic. Mammographies were assessed for BAC and thoracic CT investigations were assessed for CAC and AC. Patients included in the study were scored as 0 (none), 1 (mild), 2 (moderate), or 3 (severe) depending on the number and shape of CAC, AC, and BAC lesions observed...
February 11, 2019: Turkish Journal of Medical Sciences
Nesrin Gündüz, Gülçin Durukan, Mehmet Bilgin Eser, Ahmet Aslan, Adnan Kabaalioğlu
Background/aim: The iliac crest tangent (ICT) has recently emerged as a reliable landmark to correctly number the lumbosacral transitional vertebrae (LSTV). We retrospectively evaluated the reproducibility and accuracy of the ICT as a landmark in subjects without disc degeneration. Materials and methods: Fifty-eight patients with LSTV [19 female, 41 (26–52) years] and 55 controls without LSTV [23 female, 40 (26–55) years] who had undergone spinal computed tomography were included...
February 11, 2019: Turkish Journal of Medical Sciences
Funda Çetinkaya, Esin Kavuran, Kevser Sevgi Ünal Aslan
Background/aim: This study aimed to adapt the Amsterdam Preoperative Anxiety and Information Scale (APAIS) to measure the preoperative anxiety of adult Turkish patients undergoing surgery. Materials and methods: The sample of this methodological study included 210 patients. Data were collected by using personal information forms, the APAIS, and the State Anxiety Scale (STAI). Cronbach’s α-coefficient was calculated, and test–retest reliability was tested. Results: Cronbach’s α-coefficients of the APAIS anxiety and information requirement subscales were 0...
February 11, 2019: Turkish Journal of Medical Sciences
Refik Kunt, Mustafa Kürşad Kutluk, Bedile İrem Tiftikçioğlu, Nazire Afşar, Ali Kemal Erdemoğlu, Muhteşem Gedizlioğlu, Vesile Öztürk
Background/aim: This study aimed to investigate the consistency between stroke and general neurologists in subtype assignment using the Trial of ORG-10172 in Acute Stroke Treatment (TOAST) and Causative Classification of Stroke (CCS) systems. Materials and methods: Fifty consecutive acute ischemic stroke patients admitted to the stroke unit were recruited. Patients were classified by two stroke and two general neurologists, each from different medical centers, according to TOAST followed by the CCS...
February 11, 2019: Turkish Journal of Medical Sciences
Leyla Erdim, Ayşegül Ergün, Sema Kuğuoğlu
Background/aim: The Physical Activity Questionnaire for Older Children (PAQ-C) is one of the most frequently used questionnaires for evaluating moderate to vigorous levels of physical activity in children. However, a Turkish version of the questionnaire was not available. This study aimed to create a Turkish version of the PAQ-C and examine its psychometric characteristics and factor structure. Materials and methods: The study was conducted with 784 primary school students (ages 9–14 years)...
February 11, 2019: Turkish Journal of Medical Sciences
Sümeyye Ekmekçi, Ülkü Küçük, Yelda Dere, Ebru Çakır, Hatice Ceren Sayar, Batuhan Ergani, Özgür Çakmak, Ozan Bozkurt, Kutsal Yörükoğlu
Background/aim: This study was designed to determine the characteristic features of upper urinary system urothelial carcinomas (UUSUCs) and to evaluate the clinicopathological parameters associated with prognosis. Materials and methods: A total of 74 cases of UUSUC were included, from three different centers. Demographic data and histopathological features such as tumor localization, concomitant tumor in the urinary system, distant metastasis with overall survival and disease-free survival obtained from the hospital records were evaluated retrospectively...
February 11, 2019: Turkish Journal of Medical Sciences
İlknur Külhaş Çelik, Ersoy Civelek, Ayşe Metin, Tayfur Giniş, Müge Toyran, Emine Dibek Mısırlıoğlu, Can Naci Kocabaş
Background/aim: Ig level assessment is frequently used in the diagnosis and follow-up of immunodeficiency, as well as in studies investigating the prevalence of low serum Ig level in specific diseases. Materials and methods: Patients who underwent Ig testing in the inpatient and outpatient clinics of our hospital in the years 2010–2016 were included. The Ig levels of the patients were assessed separately according to two reference systems commonly used in Turkey and another reference system used in the USA...
February 11, 2019: Turkish Journal of Medical Sciences
Gül Sema Keskin, Özant Helvacı, Çağrı Yayla, Özge Paşaoğlu, Çağlar Keskin, Turgay Arınsoy, Ülver Derici
Background/aim: We aimed to evaluate the relationship between YKL-40 and endothelial dysfunction in chronic kidney disease. Materials and methods: Twenty-nine hemodialysis patients, 101 patients with nondialytic (stage 2, 3, 4, and 5 ND) chronic kidney disease (CKD), and 38 healthy individuals as a control group were included. YKL-40 levels were measured by ELISA. Endothelial dysfunction was indirectly measured by flow-mediated dilatation percentage (FMD) in the brachial artery...
February 11, 2019: Turkish Journal of Medical Sciences
Hatice Ataş, Müzeyyen Gönül, Yasin Öztürk, Mustafa Kavutçu
Background/aim: Results show that oxidative stress is a pathophysiologic factor for alopecia areata (AA); however, the markers used can be confounding. Thus, we aimed to investigate the role of oxidative stress in the pathogenesis of AA through an evaluation of ischemia-modified albumin (IMA); other markers of the oxidant/antioxidant system, such as SOD, CAT, GSH-ST, and MDA; and contributing clinical risk factors. Materials and methods: The usefulness of IMA as a new marker for oxidative stress was compared with that of other markers and evaluated in patients with AA...
February 11, 2019: Turkish Journal of Medical Sciences
Lamia Maknı, Cherif Ben Hamda, Abrar Al-ansarı, Oussema Souıaı, Ezzedine Gazouanı, Amel Mezlını, Wassim Almawı, Besma Yacoubı Loueslatı
Background/aim: We investigated the association of three IL-10 promoter single-nucleotide polymorphisms and altered IL-10 plasma levels with the risk of head and neck cancer (HNC). Materials and methods: Study subjects comprised 194 HNC patients [137 nasopharyngeal cancer (NPC) and 57 laryngeal cancer (LC)], and 263 healthy controls. Genotyping of rs1800896 (-1082A>G), rs1800871 (-819C>T), and rs1800872 (-592A>C) IL-10 variants was performed by real-time PCR; IL-10 levels were measured by enzyme amplified immuno sensitivity assay (EAISA)...
February 11, 2019: Turkish Journal of Medical Sciences
Zehra İpek Arslan, Zehra Türkyılmaz
Background/aim: Nasotracheal Airtraq is specifically designed to improve the glottis view and ease the nasotracheal intubation process in normal and difficult cases. Materials and methods: After Ethics committee approval, we decided to enroll 40 patients with an ASA physical status of I or II, between 18 and 70 years of age undergoing elective maxillofascial, oral, and double chin surgery to determine which nostril is more suitable for nasotracheal intubation with nasotracheal Airtraq...
February 11, 2019: Turkish Journal of Medical Sciences
Selma Korkmaz, Gülben Sayılan Özgün
Background/aim: Adropin is a peptide-structure hormone that plays a role in preventing the development of insulin resistance, which has been linked to obesity and metabolic regulation. The purpose of this study is to assess serum adropin levels and their relationship with metabolic parameters in psoriasis vulgaris patients both with and without metabolic syndrome (MetS). Materials and methods: Fifty-three patients and 26 healthy controls were included in this study...
February 11, 2019: Turkish Journal of Medical Sciences
Bahar Anaforoğlu Külünkoğlu, Fatih Erbahçeci, Afra Alkan
Background/aim: Although mirror therapy (MT) and phantom exercises (PE) have been shown to reduce pain, the efficacy of these methods in terms of pain, quality of life (QoL), and psychological status (PS) has not been investigated and compared to date. The aim of this study was to determine whether there is any difference between MT and PE in the treatment of phantom limb pain (PLP). Materials and methods: Forty unilateral transtibial amputees (aged 18–45 years) participated in this study...
February 11, 2019: Turkish Journal of Medical Sciences
Xing Lıu, Kaili Deng, Sixia Chen, Yunshi Zhang, Jing Yao, Xiaoqin Weng, Yang Zhang, Tianming Gao, Ganzhu Feng
Background/aim: 8-Hydroxy-2’-deoxyguanosine (8-OHdG) is a biomarker of oxidative stress and has been implicated in many diseases. The aim of this study was to investigate the clinical value of plasma 8-OHdG level in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Materials and methods: A total of 154 subjects were enrolled in this study, including 20 healthy volunteers, 24 COPD patients in the stable phase, and 110 AECOPD patients...
February 11, 2019: Turkish Journal of Medical Sciences
Duru Onan, Ahu Yorulmaz, Fatih Süheyl Ezgü, Kadir Mutlu Hayran, Seray Külcü, Refika Ferda Artüz, Başak Yalçın
Background/aim: Interferon-induced helicase (IFIH1) is a gene locus that has been recently defined as a candidate for susceptibility to generalized vitiligo (GV). The objectives of this study were to assess the association of IFIH1 gene, rs2111485, and rs1990760 single-nucleotide polymorphisms (SNP) with susceptibility to GV and the autoimmune diseases accompanying GV. Materials and methods: We prospectively studied GV patients and frequency-matched healthy controls by age and sex...
February 11, 2019: Turkish Journal of Medical Sciences
Cengiz Burak, Erkan Baysal, Muhammed Süleymanoğlu, Çağrı Yayla, Serkan Cay, Ümit Kervan
Background/aim: The number of patients with heart transplantation has dramatically increased in the last decade. Considerable studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarization and increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. We analyzed the dispersion of myocardial repolarization using electrocardiographic Tp-e interval and Tp-e/QTc ratio in patients with heart transplantation...
February 11, 2019: Turkish Journal of Medical Sciences
Mehmet Eser Sancaktar, Gülser Saylam, Bülent Öcal, Ahmet Uluat, Ömer Bayır, Erman Çakal, Mehmet Hakan Korkmaz
Backround/aim: Papillary thyroid carcinomas (PTC) frequently metastasize to regional lymph nodes. Our purpose was to investigate the predictive role of tumor location for lymph node metastasis pattern in PTCs. Materials and methods: Medical records of 110 PTC patients were reviewed retrospectively. Tumor location was determined as upper, middle, and lower pole according to ultrasonography (USG) findings. The effects of age, sex, tumor size, and location on lymph node metastasis were investigated...
February 11, 2019: Turkish Journal of Medical Sciences
Emre Kara, Ahmet Çağkan İnkaya, Duygu Aydın Haklı, Kutay Demirkan, Serhat Ünal
Background/aim: The HIV-infected population is aging, and the concomitant comorbidities increase the likelihood of polypharmacy. There is a scarcity of data for determining drug-related problems in people living with HIV/AIDS (PLWHA). Materials and methods: This cross-sectional study was carried out between 1 September 2015 and 1 July 2016. All patients underwent a face-to-face interview with a clinical pharmacist. PCNE Classification V 7.0 was used classify incident drug-related problems (DRPs)...
February 11, 2019: Turkish Journal of Medical Sciences
Davut Sinan Kaplan, Cahit Bağcı, Mustafa Örkmez, Özge Kömürcü Karuserci, Seyhan Sucu, Hakim Çelik, Seyithan Taysı
Background/aim: The aims of this study were to determine the levels of the total antioxidant status (TAS), the total oxidant status (TOS), the oxidative stress index (OSI), and the concentration of immunoglobulin A (IgA) and M (IgM) in colostrum, and evaluate relationships between these parameters and maternal age, maternal parity, and infant sex. Materials and methods: The analysis was performed in serum samples of colostrum which were collected from 90 mothers on the first day of lactation between 10:00 and 12:00 AM Results: The measurements established that no significant association existed between the TAS level of colostrum and parity, maternal age, or infant sex...
February 11, 2019: Turkish Journal of Medical Sciences
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