journal
https://read.qxmd.com/read/38546937/observational-retrospective-study-in-patients-treated-with-galcanezumab-as-preventive-treatment-for-migraine-the-orygam-study
#1
JOURNAL ARTICLE
Samuel Díaz Insa, Ángel Guerrero, Javier Viguera, Vicente Medrano Martínez, Carlos Calle de Miguel, Jesús Porta-Etessam, Antonio Ciudad, Silvia Diaz-Cerezo, Ana Roncero Martín, Mercedes Núñez
INTRODUCTION: The efficacy of galcanezumab has been demonstrated in randomized controlled trials, but evidence about its use under clinical practice conditions is still limited. This study aimed to describe the characteristics of the patients treated with galcanezumab in routine clinical practice in Spain as well as treatment patterns, persistence, and effectiveness. METHODS: A retrospective chart review study was carried out in six hospitals. Information of adults with migraine, who started treatment with galcanezumab between November 2019 and September 2021, was analyzed until end or loss of follow-up...
March 28, 2024: Pain and Therapy
https://read.qxmd.com/read/38520658/pacific-spine-and-pain-society-psps-evidence-review-of-surgical-treatments-for-lumbar-degenerative-spinal-disease-a-narrative-review
#2
REVIEW
Michael J Dorsi, Patrick Buchanan, Chau Vu, Harjot S Bhandal, David W Lee, Samir Sheth, Phil M Shumsky, Nolan J Brown, Alexander Himstead, Ryan Mattie, Steven M Falowski, Ramana Naidu, Jason E Pope
INTRODUCTION: Interventional treatment options for the lumbar degenerative spine have undergone a significant amount of innovation over the last decade. As new technologies emerge, along with the surgical specialty expansion, there is no manuscript that utilizes a review of surgical treatments with evidence rankings from multiple specialties, namely, the interventional pain and spine communities. Through the Pacific Spine and Pain Society (PSPS), the purpose of this manuscript is to provide a balanced evidence review of available surgical treatments...
March 23, 2024: Pain and Therapy
https://read.qxmd.com/read/38489096/analyzing-the-effect-of-intraoperative-stimulation-voltage-on-facial-numbness-following-radiofrequency-thermocoagulation-in-the-treatment-of-idiopathic-trigeminal-neuralgia
#3
JOURNAL ARTICLE
Aitao Wang, Jingjing Bian, Na Li, Jiaxiang Ni, Lea Zila, Yuanzhang Tang
INTRODUCTION: Radiofrequency thermocoagulation (RFT) effectively alleviates idiopathic trigeminal neuralgia (ITN); however, postoperative facial numbness poses a significant challenge. This issue arises due to the close proximity of high-temperature thermocoagulation, which not only ablates pain-related nociceptive fibers but also affects tactile fibers. Intraoperative sensory stimulation voltage (SV), which reflects the distance between the RFT cannula and the target nerve, potentially possesses the ability to prevent tactile fiber injury...
March 15, 2024: Pain and Therapy
https://read.qxmd.com/read/38478173/effects-of-different-volumes-of-ropivacaine-for-pericapsular-nerve-group-block-on-incidence-of-quadriceps-weakness-and-analgesic-efficacy-following-hip-arthroplasty-a-randomized-controlled-trial
#4
JOURNAL ARTICLE
Huaichang Wen, Weihua Zhang, Yi Wang, Meijing Lu
INTRODUCTION: The pericapsular nerve group (PENG) block has been shown to be an effective approach to alleviating pain and reducing the need for opioids among older adults following hip surgery, with possible motor-sparing effects. No reports to date, however, have described appropriate ropivacaine volumes for use in the context of PENG block. The present prospective randomized controlled study was thus developed to assess the quadriceps muscle strength and analgesic efficacy associated with PENG block performed using three different volumes of 0...
March 13, 2024: Pain and Therapy
https://read.qxmd.com/read/38472655/real-world-impact-of-fremanezumab-on-migraine-related-health-care-resource-utilization-in-patients-with-comorbidities-acute-medication-overuse-and-or-unsatisfactory-prior-migraine-preventive-response
#5
JOURNAL ARTICLE
Dawn C Buse, Lynda J Krasenbaum, Michael J Seminerio, Elizabeth R Packnett, Karen Carr, Mario Ortega, Maurice T Driessen
INTRODUCTION: Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene-related peptide, is indicated for preventive treatment of migraine in adults. Real-world evidence assessing the effect of fremanezumab on migraine-related medication use, health care resource utilization (HCRU), and costs in patient populations with comorbidities, acute medication overuse (AMO), and/or unsatisfactory prior migraine preventive response (UPMPR) is needed. METHODS: Data for this US, retrospective claims analysis were obtained from the Merative® MarketScan® Commercial and supplemental databases...
March 12, 2024: Pain and Therapy
https://read.qxmd.com/read/38446344/the-role-of-the-combination-paracetamol-caffeine-in-treatment-of-acute-migraine-pain-a-narrative-review
#6
REVIEW
Barbanti Piero, Allais Gianni, Cevoli Sabina, Guerzoni Simona, Valeriani Massimiliano, Vernieri Fabrizio
INTRODUCTION: Thirty years ago, the first migraine-specific drugs (triptans) appeared. Today two new categories (gepants and ditans) are marketed for acute migraine treatment. That said, is there still a role for conventional therapy? The aim of the present narrative review is to provide an expert overview examining the possible role of the combination paracetamol/caffeine in treatment of acute migraine pain. METHODS: To understand possible settings for more appropriate use of paracetamol/caffeine (1000 mg/130 mg) in treatment of acute migraine, a structured literature search was performed using the PubMed database by a panel of experts from major Italian headache centers; articles not referring to migraine pain were excluded from this review; review articles were prioritized...
March 6, 2024: Pain and Therapy
https://read.qxmd.com/read/38430433/incorporation-of-artificial-intelligence-for-objective-pain-assessment-a-comprehensive-review
#7
REVIEW
Salah N El-Tallawy, Joseph V Pergolizzi, Ingrid Vasiliu-Feltes, Rania S Ahmed, JoAnn K LeQuang, Hamdy N El-Tallawy, Giustino Varrassi, Mohamed S Nagiub
Pain is a significant health issue, and pain assessment is essential for proper diagnosis, follow-up, and effective management of pain. The conventional methods of pain assessment often suffer from subjectivity and variability. The main issue is to understand better how people experience pain. In recent years, artificial intelligence (AI) has been playing a growing role in improving clinical diagnosis and decision-making. The application of AI offers promising opportunities to improve the accuracy and efficiency of pain assessment...
March 2, 2024: Pain and Therapy
https://read.qxmd.com/read/38407769/sacroiliac-joint-denervation-a-novel-approach-to-target-sacral-lateral-branches-a-practical-approach
#8
JOURNAL ARTICLE
Victor M Silva-Ortiz, Kenneth B Chapman, George C Chang Chien, Sudhir Diwan, Alaa Abd-Elsayed
INTRODUCTION: Sacroiliac joint (SIJ) pain is a relatively common cause of low back pain. Percutaneous radiofrequency (RF) techniques for SIJ are limited to ablation of the posterior SIJ innervation. Different techniques have been described for SIJ radiofrequency ablation, including conventional thermal, cooled RF, pulsed RF, bipolar RF, and specialized tip RF needle (i.e., multi-tined); however, additional costs may limit these applications. METHODS: This new technique for SIJ denervation uses anatomical landmarks and a single RF cannula...
February 24, 2024: Pain and Therapy
https://read.qxmd.com/read/38386183/letter%C3%A2-to%C3%A2-the%C3%A2-editor%C3%A2-regarding-the-role-of-ultrasound-guided-multipoint-fascial-plane-block-in-elderly-patients-undergoing-combined-thoracoscopic-laparoscopic-esophagectomy-a-prospective-randomized-study
#9
LETTER
https://read.qxmd.com/read/38367159/efficacy-of-transcutaneous-electrical-acupoint-stimulation-on-chronic-postsurgical-pain-after-video-assisted-thoracoscopic-lobectomy-study-protocol-for-a-prospective-randomized-controlled-trial
#10
JOURNAL ARTICLE
Shuang Chen, Ying Ding, Xiaoming Zhang, Xue Zhang, Jiajia Xiang, Yiling Deng, Xingran Tao, Wenke Cai, Zhigui Li, Jiayu Chen, Fanyi Kong, Na Li
INTRODUCTION: Patients undergoing video-assisted thoracoscopic lobectomy (VATL) often experience chronic postsurgical pain (CPSP). Postoperative pain can affect the recovery of postoperative lung function, prolong postoperative recovery time, and increase patient hospitalization expenses. Transcutaneous electrical acupoint stimulation (TEAS) is an alternative therapy based on acupuncture that has shown promise in postoperative recovery and pain management across various medical fields...
February 17, 2024: Pain and Therapy
https://read.qxmd.com/read/38315379/association-of-range-of-motion-deficit-and-recurrence-of-pain-after-treatment-of-adhesive-capsulitis
#11
JOURNAL ARTICLE
Jung Hwan Lee, Jun Ho Lee, Min Cheol Chang
INTRODUCTION: We evaluated the factors influencing the duration of significant pain reduction after conservative management for adhesive capsulitis (AC). METHODS: Follow-up for 6-8 months was performed with 141 patients with AC who experienced significant pain reduction after treatment. Clinical and demographic factors, numeric rating scale (NRS) scores, and shoulder range of motion (ROM) were collected and assessed pretreatment (T0), at 5 weeks post-treatment (T1), and at 6-8 months post-treatment (T2)...
February 5, 2024: Pain and Therapy
https://read.qxmd.com/read/38315378/additional-effect-of-extracorporeal-shockwave-therapy-with-lidocaine-injection-on-clinical-and-mri-findings-in-frozen-shoulder-a-prospective-randomized-double-blinded-placebo-controlled-trial
#12
JOURNAL ARTICLE
Gopal Nambi, Mshari Alghadier, Mudathir Mohamedahmed Eltayeb, Osama R Aldhafian, Ayman K Saleh, Nesreen Alsanousi, Mohamed Nagah Ahmed Ibrahim, Abdehamid A Attallah, Mohammed Abdelgwad Ismail, Mohamed Elfeshawy, Yaser El Sayed Hasan Wahd, Alaa Jameel A Albarakati
INTRODUCTION: Frozen shoulder is a very common musculoskeletal condition and the evidence related to the additional effects of extracorporeal shockwave therapy (ESWT) with intra-articular (IA) lidocaine injection in individuals with frozen shoulder is rare. Therefore, this study aims to compare and investigate the additional effects of extracorporeal shockwave therapy (ESWT) with intra-articular (IA) lidocaine injection in a frozen shoulder. METHODS: Sixty eligible participants with frozen shoulder were included and the active group (n = 30, age 52...
February 5, 2024: Pain and Therapy
https://read.qxmd.com/read/38300395/classical-tap-vs-i-tap-using-the-same-dose-of-local-anesthetic-in-elective-cesarean-section-a-randomized-controlled-trial
#13
JOURNAL ARTICLE
Wessam Zakaria El-Amrawy, Ahmed Mohamed El-Attar
INTRODUCTION: The effectiveness of postoperative pain control following a Cesarean section influences mother-child attachment, improves early healing, and undoubtedly hastens discharge. Transverse abdominis plane (TAP) and ilioinguinal iliohypogastric (ILIH) blocks have been used to minimize postoperative opioid intake, although their relative effectiveness is unknown. The study aims to determine which procedure was more effective at reducing the need for postoperative rescue analgesics after lower segment Cesarean section (LSCS)...
February 1, 2024: Pain and Therapy
https://read.qxmd.com/read/38300394/efficacy-and-safety-of-epidural-chloroprocaine-for-breakthrough-pain-during-labor-analgesia-a-prospective-double-blind-randomized-trial
#14
JOURNAL ARTICLE
Tianzhen Ji, Can Jiang, Hongxia Liu, Zhehao Cai, Rongrong Liu, Lei Xie, Cheng Xu
INTRODUCTION: A significant number of women who undergo neuraxial labor analgesia experience breakthrough pain. Prompt mitigation of breakthrough pain is essential to improve maternal and fetal outcomes. We evaluated epidural chloroprocaine compared with ropivacaine in alleviating labor breakthrough pain. METHODS: We performed a double-blind randomized controlled clinical trial between May and July 2023. Eligible parturients received epidural analgesia with ropivacaine and sufentanil...
February 1, 2024: Pain and Therapy
https://read.qxmd.com/read/38281221/intraoperative-opioid-waste-and-association-of-intraoperative-opioid-dose-with-postoperative-adverse-outcomes-a-hospital-registry-study
#15
JOURNAL ARTICLE
Simone Redaelli, Aiman Suleiman, Dario von Wedel, Sarah Ashrafian, Ricardo Munoz-Acuna, Guanqing Chen, Mitra Khany, Catriona Stewart, Nikolai Ratajczak, John Hertig, Sarah Nabel, Maximilian S Schaefer, Satya Krishna Ramachandran
INTRODUCTION: Perioperative opioid use has been associated with adverse clinical outcomes. Additionally, opioid disposal carries significant costs, due to the waste of pharmaceutical products and the time needed by skilled labor to report the waste. In this study, we aimed to estimate costs and predict factors of opioid-associated intraoperative product waste, as well as to evaluate whether higher intraoperative opioid doses are associated with increased risk of adverse postoperative outcomes...
January 28, 2024: Pain and Therapy
https://read.qxmd.com/read/38280148/letter-to-the-editor-regarding-effect-of-erector-spinae-plane-block-in-terms-of-analgesic-efficacy-in-elderly-patients-undergoing-posterior-lumbar-spine-surgery
#16
LETTER
Raghuraman M Sethuraman, Shanmuga Priya Arulmozhi, Divyashree Sathyaprakash, Raj Murugan
No abstract text is available yet for this article.
January 27, 2024: Pain and Therapy
https://read.qxmd.com/read/38280147/unmet-needs-of-patients-living-with-migraine-in-the-gulf-cooperation-council-gcc-countries
#17
REVIEW
Abdulrazaq Albilali, Jasem Al-Hashel, Ziad Elchami, Suhail Al Rukn, Abu Baker Al Madani, Muna AlTunaiji, Jalal Al Ali, Mohamed Fathy, Jean Joury
The scale of migraine and its impact on the lives of patients in the Gulf Cooperation Council (GCC) countries may be underestimated by healthcare professionals and the public and unmet needs in the provision of migraine medical care may exist. This article reports the key outcomes from a meeting of migraine specialists and their patients organised by the Emirates Neurology Society to learn more about the patient diagnosis and treatment journey and the extent to which migraine affects daily life. Patient stories indicate that the burden of migraine is underestimated, migraine is not generally recognised as a disease, delayed and incorrect diagnoses are common, and that achieving symptom control is often more a question of good luck rather than good management...
January 27, 2024: Pain and Therapy
https://read.qxmd.com/read/38183573/model-based-meta-analysis-supporting-the-combination-of-acetaminophen-and-topical-diclofenac-in-acute-pain-a-therapy-for-mild-to-moderate-osteoarthritis-pain
#18
JOURNAL ARTICLE
Vidhu Sethi, Li Qin, Eugène Cox, Iñaki F Trocóniz, Oscar Della Pasqua
INTRODUCTION: Acetaminophen and topical diclofenac (AtopD) have complementary mechanisms of action and are therefore candidates for combination use in osteoarthritis (OA) pain. However, an evidence gap exists on their combination use in OA pain. This study aimed to assess the effects of this combination and compare its performance relative to monotherapies on pain score reduction and opioid-sparing effect by leveraging evidence from acute pain setting using a model-based meta-analysis (MBMA)...
January 6, 2024: Pain and Therapy
https://read.qxmd.com/read/38183572/model-based-assessment-of-the-liver-safety-profile-of-acetaminophen-to-support-its-combination-use-with-topical-diclofenac-in-mild-to-moderate-osteoarthritis-pain
#19
JOURNAL ARTICLE
Vidhu Sethi, Li Qin, Iñaki F Trocóniz, Luke Van der Laan, Eugène Cox, Oscar Della Pasqua
INTRODUCTION: The use of combination therapy of oral acetaminophen and topical diclofenac, having complementary mechanisms of action, is an attractive strategy to enhance the analgesic response in osteoarthritis (OA) pain. While topical diclofenac is considered as well tolerated due to its low systemic exposure, concerns of liver toxicity with acetaminophen at standard analgesic doses remain. Thus, this study aimed to assess the liver safety profile of acetaminophen, particularly in OA management, using a model-based meta-analysis (MBMA)...
January 6, 2024: Pain and Therapy
https://read.qxmd.com/read/38180725/h-wave-%C3%A2-device-stimulation-for-chronic-low-back-pain-a-patient-reported-outcome-measures-proms-study
#20
JOURNAL ARTICLE
Stephen M Norwood, David Han, Ashim Gupta
INTRODUCTION: Chronic low back pain (cLBP) is a problem globally, creating a tremendous economic burden. Since conventional treatments often fail, various forms of electrical stimulation have been proposed to improve function and decrease pain. Patient-reported outcome measures (PROMs) have not been adequately reported in the electrical stimulation literature. METHODS: A retrospective independent statistical analysis was conducted on PROMs data for users of H-Wave® device stimulation (HWDS) collected by the device manufacturer over a period of 4 years...
January 5, 2024: Pain and Therapy
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