journal
Journals Journal of Global Antimicrobia...

Journal of Global Antimicrobial Resistance

https://read.qxmd.com/read/38519025/simultaneous-post-neurosurgical-ventriculitis-and-bacteremia-by-two-different-strains-of-kpc-producing-k-pneumoniae-successfully-treated-with-meropenem-vaborbactam-and-high-dose-of-fosfomycin
#1
JOURNAL ARTICLE
Lorenzo Volpicelli, Sara Cairoli, Dania Al Ismail, Floriana Baisi, Federica Sacco, Bianca Maria Goffredo, Mario Venditti, Alessandra Oliva
A case of post-neurosurgical ventriculitis caused by a KPC-producing Klebsiella pneumoniae (KPC-Kp) with a ceftazidime/avibactam-resistant, meropenem-susceptible phenotype is reported. The patient had a concomitant bloodstream infection with a wild-type KPC-Kp with a ceftazidime/avibactam-susceptible, meropenem-resistant phenotype. Prolonged treatment with intravenous fosfomycin and meropenem/vaborbactam achieved clinical success. Therapeutic drug monitoring performed during the first days of treatment showed for the first time that vaborbactam efficiently penetrates cerebrospinal fluid...
March 20, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38462073/the-first-reported-pulmonary-nocardiosis-caused-by-nocardia-gipuzkoensis-resisted-to-tmp-smz-in-an-immunocompetent-patient
#2
JOURNAL ARTICLE
Yishan Duan, Xiaoxia Zhang, Wen Deng, Suyan Wang, Jinrui Hu, Xiaohui Wang, Weimin Li, Bojiang Chen
BACKGROUND: . Nocardia gipuzkoensis was first described as a novel and distinct species in 2020 by Imen Nouioui and pulmonary nocardiosis associated with Nocardia gipuzkoensis was once reported in two bronchiectasis patients. Noteworthy, both reported Nocardia gipuzkoensis cases showed sensitivity to Trimethoprim/Sulfamethoxazol (TMP-SMZ), which are usually recommended for empirical therapy. METHODS: We reported the third case of Nocardia gipuzkoensis infection in a 16-year-old girl with chief complaints of cough, persistent chest and back pain...
March 8, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38460750/genomic-characterization-of-bla-ndm-5-incx3-plasmid-in-a-st4-klebsiella-aerogenes-clinical-isolate
#3
JOURNAL ARTICLE
Fen Pan, Qi Xu, Cong Jiang, Qingqing Du, Fangyuan Yu, Pengcheng Chen, Hong Zhang
OBJECTIVE: The dissemination of New Delhi metallo-β-lactamase-5 (NDM-5) among various species of Enterobacteriales has attracted serious global attention. Here, we characterized the genomic characterization of blaNDM-5-IncX3 plasmid (pNDM-KA3) in a ST4 Klebsiella aerogenes (KA3) strain isolated from a neonate with pneumonia. METHODS: Antimicrobial susceptibility and multilocus sequence typing were performed for the KA3. Plasmid conjugation assay and plasmid stability of the KA3 (pNDM-KA3) were also analyzed...
March 7, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38458537/changes-in-antimicrobial-resistance-of-escherichia-coli-isolated-from-community-associated-urinary-tract-infection-before-and-during-the-covid-19-pandemic-in-india
#4
JOURNAL ARTICLE
Shwetha Venugopal, Sneha Chunchanur, Rajashree Panigrahy, Vibhor Tak, Manish Yadav, Akanksha Chauhan, Himabindhu Ks, Jayapriya R, Swati Pundir, Satyendra Bhatt, Birasen Behera, Sumanth M, Ambica R, Susmita Chaudhuri, Sarita Mohapatra
PURPOSE: Impact of COVID-19 pandemic on antimicrobial resistance (AMR) is largely studied in healthcare settings, there is a need to understand the fluctuations in AMR during pandemic at the community level. Urinary tract infection (UTI) being one of the most common infections in the community, AMR profile of Community-acquired UTI (CA-UTI) is considered representative AMR at the community level. PATIENTS AND METHODS: The study was taken in cohort of patients with clinical diagnosis of CA-UTI...
March 6, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38458536/the-features-of-multidrug-resistant-organisms-between-2016-and-march-2023-and-its-change-after-the-end-of-zero-covid-19-policy-in-a-teaching-hospital-in-shenzhen-china
#5
JOURNAL ARTICLE
Hongwei Shen, Danli Xiao, Qiaomin Zhang, Shaobo Li, Haihong He, Xiaoyan Dai, Hanlian Huang, Wen Ma
No abstract text is available yet for this article.
March 6, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38452900/pseudomonas-aeruginosa-strains-isolated-from-animal-with-high-virulence-genes-content-and-highly-sensitive-to-antimicrobials
#6
JOURNAL ARTICLE
Rosario Morales-Espinosa, Gabriela Delgado, Fernando Espinosa-Camacho, Alejandro Flores-Alanis, Cristina Rodriguez, Jose L Mendez, Alejandro Cravioto
P. aeruginosa is one of the most metabolically versatile bacteria having the ability to survive in multiple environments through its accessory genome. An important hallmark of P. aeruginosa is the high level of antibiotic resistance, which often makes eradication difficult and sometimes impossible. Evolutionary forces have led to this high microbial resistance with a variety of elements contributing to both intrinsic and acquired resistance by this bacterium. As such, P. aeruginosa infection is linked with high mortality rates in humans, but in animals is not well documented...
March 5, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38430961/genetic-characterization-of-khm-1-metallo-%C3%AE-lactamase-producing-enterobacterales-isolates-from-inpatient-sources-in-osaka-japan
#7
JOURNAL ARTICLE
Kaoru Umeda, Masaki Anraku, Takahiro Yamaguchi, Hiromi Nakamura, Ryuji Kawahara
OBJECTIVES: KHM-1-metallo-β-lactamase-producing Enterobacterales strains, of which only a few have been found, were isolated from four inpatients in Osaka, Japan during 2016-2020. We compared whole genomes of the four KHM-1-producing isolates, including one Enterobacter hormaechei subsp. hoffmannii, one Escherichia coli, and two Citrobacter freundii. METHODS: These isolates were characterized by whole-genome sequencing, comparative analysis of blaKHM-1 -encoding plasmids with earlier reported plasmids, and antimicrobial susceptibility tests...
February 29, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38428456/genomic-analysis-of-a-pseudomonas-aeruginosa-strain-harboring-bla-kpc-2-and-bla-oxa-129-belonging-to-high-risk-clone-st235-in-brazil
#8
LETTER
Tiago Barcelos Valiatti, Ana Paula Streling, Rodrigo Cayô, Fernanda Fernandes Santos, Myriam Santos Almeida, Marco André Loureiro Tonini, Ana Cristina Gales
No abstract text is available yet for this article.
February 28, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38423210/report-of-salmonella-saintpaul-from-chicken-carcass-co-harbouring-bla-ctx-m2-and-mcr-9-1
#9
LETTER
Arthur de Almeida Figueira, Thomas Salles Dias, Gisllany Alves Costa, Giovanna Silva de Souza, Dayse Lima da Costa Abreu, Luciana Dos Santos Medeiros, Virginia Léo de Almeida Pereira
No abstract text is available yet for this article.
February 27, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38417739/draft-genome-sequence-analysis-of-a-mcr-1-producing-klebsiella-pneumoniae-st661-isolated-from-a-mink-in-china
#10
JOURNAL ARTICLE
Na Sun, Yilin Luo, Yaru Zhao, Guisheng Wang, Li Guo, Liming Liu, Zhihao San, Cuiqing Zhao, Yuening Cheng, Qiang Chen
OBJECTIVES: Klebsiella pneumoniae is a major opportunistic pathogen that is a member of the Enterobacteriaceae. K. pneumoniae causes pneumonia in mink and has become the primary infectious disease that limits mink farming. In this study, we report the draft genome sequence of a multidrug-resistant (MDR) strain of K. pneumoniae that harbours the mcr-1 gene isolated from a mink in China. METHODS: The agar microdilution method was used to determine the minimum inhibitory concentration of the strain...
February 26, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38417738/chloramphenicol-activity-against-carbapenemase-producing-enterobacterales
#11
LETTER
Giulio Camarlinghi, Eva Maria Parisio, Alberto Antonelli, Marco Coppi, Claudia Niccolai, Tommaso Giani, Gian Maria Rossolini
No abstract text is available yet for this article.
February 26, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38412920/characterization-of-an-incx4-plasmid-harbouring-mcr-1-from-escherichia-fergusonii-from-chicken-meat-in-china
#12
LETTER
Cai-Yue Mei, Xing-Xing Zhang, Yue Jiang, Qin-Chun Ma, Zhen-Yu Wang, Xinan Jiao, Fa-Gang Zhong, Jing Wang
No abstract text is available yet for this article.
February 25, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38412919/clinical-characteristics-and-risk-factors-for-neonatal-bloodstream-infection-due-to-carbapenem-resistant-enterobacteriaceae-a-single-center-chinese-retrospective-study
#13
JOURNAL ARTICLE
Panpan Fang, Kaijie Gao, Junmei Yang, Tiewei Li, Qianqian Sun, Zhiming Shan, Yingyuan Wang
OBJECTIVES: To analyze the clinical characteristics and risk factors for bloodstream infections (BSIs) caused by carbapenem-resistant Enterobacteriaceae (CRE) in neonates. METHODS: This single-center, retrospective study included all patients with BSIs admitted to a neonatal intensive care unit between Jan 1, 2015 to Apr 30, 2022. The clinical and microbiological data of patients were collected; predictors of 30-day mortality in patients with CRE BSIs were also identified in this study...
February 25, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38408565/candida-glabrata-hospital-isolate-from-lebanon-reveals-micafungin-resistance-associated-with-increased-chitin-and-resistance-to-a-cell-surface-disrupting-agent
#14
JOURNAL ARTICLE
Nour Fattouh, Roy A Khalaf, Rola Husni
OBJECTIVES: The aim of this study was to identify the resistance mechanisms to micafungin and fluconazole in a clinical isolate of Candida glabrata. METHODS: The isolate was whole genome sequenced in order to identify amino acid changes in key proteins involved in antifungal resistance and the isolate was further characterized by pathogenicity related phenotypic assays that supported the sequencing results. RESULTS: Amino acid substitutions were detected in 8 out of 17 protein candidates...
February 24, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38408564/co-existence-of-bla-ndm-5-bla-ctx-m-15-bla-oxa-232-bla-shv-182-genes-in-multi-drug-resistant-k-pneumoniae-st437-carrying-ompk36-and-ompk37-porin-mutations-first-report-in-italy
#15
JOURNAL ARTICLE
S Di Marcantonio, M Perilli, G Alloggia, B Segatore, G Miconi, G Bruno, P Frascaria, A Piccirilli
OBJECTIVES: K. pneumoniae is a common cause of severe hospital-acquired infections. In the present study we have characterized the whole-genome of two K. pneumoniae ST437 belonging to the clonal complex CC258. METHODS: The whole-genome sequencing was performed by MiSeq Illumina, with a 2×300bp paired-end run. ResFinder 4.4.2 was used to detect acquired antimicrobial resistance genes (ARGs) and chromosomal mutations. Mobile genetic elements (plasmids and ISs) were identified by MobileElementFinder v1...
February 24, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38408563/coexistence-of-virulent-and-multidrug-resistant-plasmids-in-a-uropathogenic-escherichia-coli
#16
JOURNAL ARTICLE
Yongli Wu, Ziyao Li, Zichen Lei, Jiankang Zhao, Yulin Zhang, Xinmeng Liu, Yanning Hu, Feilong Zhang, Binghuai Lu
OBJECTIVES: The emergence of pathogens co-harboring multiple mobile resistance and virulence elements is of great concern in clinical settings. Herein, we report an O101: H10-ST167 Escherichia coli Hu106 strain isolated from the urinary tract of a female in China. METHODS: Antibiotic susceptibility testing was used to present the antimicrobial resistance spectrum. Whole-genome sequencing (WGS) and bioinformatic analysis were used to clarify the virulent and resistance mechanisms...
February 24, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38408562/genomic-insights-into-an-extensively-drug-resistant-and-hypervirulent-burkholderia-dolosa-n149-isolate-of-a-novel-sequence-type-st2237-from-a-vietnamese-patient-hospitalized-for-stroke
#17
JOURNAL ARTICLE
Nguyen Quang Huy, Nguyen Cam Linh, Nguyen Thai Son, Do Bich Ngoc, Tran Thi Thanh Tam, Le Thi Thu Hang, Bui Thanh Thuyet, Le Huu Song, Dong Van Quyen, Juliette Hayer, Anne-Laure Bañuls, Bui Tien Sy
OBJECTIVES: Burkholderia dolosa is a clinically important opportunistic pathogen in inpatients. Here we characterized an extensively drug-resistant and hypervirulent B. dolosa isolate from a patient hospitalized for stroke. METHODS: Resistance to 41 antibiotics was tested with the agar disc diffusion, minimum inhibitory concentration, or broth microdilution method. The complete genome was assembled using short-reads and long-reads and the hybrid de novo assembly method...
February 24, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38408561/hybrid-genome-assembly-of-colistin-resistant-mcr-1-5-producing-escherichia-coli-st354-reveals-phylogenomic-pattern-associated-with-urinary-tract-infections-in-brazil
#18
JOURNAL ARTICLE
Bruna Fuga, Fábio P Sellera, Fernanda Esposito, Quézia Moura, Marcelo Pillonetto, Nilton Lincopan
BACKGROUND: The rapid and global spread of Escherichia coli carrying mcr-type genes at the human-animal-environmental interface has become a serious global public health problem. OBJECTIVE: To perform a genomic investigation of a colistin-resistant E. coli strain (14005RM) causing urinary tract infection, using a hybrid de novo assembly of Illumina/Nanopore sequence data, presenting phylogenomic insights into relationship with mcr-1-positive strains circulating at the human-animal-environmental interface, in Brazil...
February 24, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38408560/co-existence-of-tmexcd2-toprj2-and-bla-ndm-1-on-a-single-plasmid-carried-by-raoultella-ornithinolytica-isolated-from-public-garbage-bins
#19
LETTER
Jie Li, Xiaoqian Long, Hui Lin, Caihong Song, Guoping Zhao, Biao Tang
No abstract text is available yet for this article.
February 24, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38342378/evaluation-of-clinical-and-microbiological-factors-related-to-mortality-in-patients-with-gram-negative-bacterial-infections-treated-with-ceftazidime-avibactam-a-prospective-multicentric-cohort-study
#20
JOURNAL ARTICLE
Beatriz Arns, Guilherme Geraldo Lovato Sório, Tarsila Vieceli, Dariane Pereira, Andrea Souza, Priscila Wink, Dariane Pereira, Julia Hoefel Paes, Leonardo David, Fernanda Barboza, Stella Hickmann, Gustavo Alves, Antônio Cândido Santos, Anelise da Rosa, Marcelle Alves, Cibele Magagnin, Eduardo Gomes, Alexandre Prehn Zavascki, Maria Helena Rigatto
OBJECTIVES: This study aimed to evaluate the clinical and microbiological risk factors associated with mortality in patients treated with ceftazidime-avibactam for carbapenem-resistant gram-negative bacterial infections. METHODS: This multicentric prospective cohort study included hospitalized adult patients with a microbiologically confirmed infection treated with ceftazidime-avibactam for ≥48 hours. The clinical and microbiological risk factors for 30-day mortality were evaluated using a Cox regression model...
February 9, 2024: Journal of Global Antimicrobial Resistance
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