journal
Journals Journal of Research in Pharmac...

Journal of Research in Pharmacy Practice

https://read.qxmd.com/read/38716324/follow-up-of-methanol-related-visual-defects-in-a-cohort-study-initial-severity-predicts-long-term-outcome
#1
JOURNAL ARTICLE
Farzad Gheshlaghi, Anselm Wong, Rezvan Firuzfar, Keyvan Jenab, Shayan Gheshlaghi, Golnoosh Shahverdi, Nastaran Eizadi-Mood
OBJECTIVE: Methanol poisoning can occur either intentionally through the consumption of methanol-containing products or accidentally through ingestion, resulting in visual impairment. We assessed the long-term visual sequelae in patients with methanol poisoning. METHODS: This prospective cohort study was conducted at referral centers, Khorshid and Alzahra University Hospitals, affiliated with Isfahan University of Medical Sciences, Isfahan, Iran. The study included patients hospitalized for methanol poisoning from June 22, 2018, to June 21, 2020, with follow-up extended until June 2021...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38716323/efficacy-of-an-oral-solution-containing-five-herbal-extracts-in-the-treatment-of-urolithiasis-a-randomized-single-blind-placebo-controlled-clinical-trial
#2
JOURNAL ARTICLE
Sahand Samandarian, Rasool Soltani, Valiollah Hajhashemi, Mehdi Dehghani, Mohammad Matinfar, Mohaddese Mahboubi, Afsaneh Mohsenzadeh
OBJECTIVE: The high prevalence of urolithiasis and its recurrence entail the preparation of an efficient drug with the least side effects. Tribulus terrestris , Urtica dioica , Adiantum capillus-veneris , Stigma maydis (corn silk), and Cucumis melo are herbal remedies utilized in traditional medicine for urolithiasis. This study aimed to assess the efficiency of these plants' extracts in treating urolithiasis. METHODS: In a randomized, single-blind, placebo-controlled clinical trial, participants meeting inclusion criteria were randomly allocated to the drug ( n = 27) and placebo ( n = 27) groups to take herbal or placebo solutions, respectively, at a dose of 60 drops 3 times daily for 4 weeks with standard treatment...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38716322/successful-stem-cell-mobilization-and-cd34-cell-collection-in-a-poor-mobilizer-a-case-report-utilizing-a-combination-of-recombinant-growth-colony-stimulating-factor-recombinant-human-growth-factor-and-plerixafor
#3
Maliheh Kazemi Najafabadi, Azadeh Moghaddas, Mozhgan Karimifar, Ali Darakhshandeh
Diffuse large B-cell lymphoma is the most prevalent form of non-Hodgkin's lymphoma that is usually treated with chemoimmunotherapy. If the disease proves refractory or recurrent, the primary treatment approach involves high-dose chemotherapy with bone marrow transplantation. The collection of peripheral blood stem cells before transplantation plays a vital role in the treatment process, necessitating the mobilization of blood stem cells from the bone marrow to the peripheral blood. Despite using standard methods such as granulocyte colony-stimulating factor (G-CSF), chemotherapy, and plerixafor, some patients cannot collect an optimal count of CD34+ cells for transplantation...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38716321/hypoglycemic-agents-and-anesthetic-techniques-to-ameliorate-stress-hyperglycemia-in-critically-ill-patients-a-systematic-review
#4
JOURNAL ARTICLE
Fatemeh Rahimpour, Malihe Nejati, Azadeh Moghaddas, Shadi Farsaei, Awat Feizi
The concurrent utilization of hypoglycemic agents and anesthetic techniques has been demonstrated to mitigate stress hyperglycemia in critically ill patients without diabetes, thereby contributing to enhanced patient outcomes. Stress hyperglycemia, characterized by elevated blood glucose levels as a result of acute illness or physiological stress, frequently manifests in patients experiencing critical illness. This condition has been linked to augmented morbidity, protracted hospitalization durations, and elevated mortality rates...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38716320/the-effectiveness-of-perovskia-abrotanoides-extract-topical-formulation-on-the-cutaneous-leishmaniasis-a-randomized-controlled-clinical-trial
#5
JOURNAL ARTICLE
Maryam Sadat Tayebi, Nazila Poostiyan, Masoud Sadeghi Dinani, Erfaneh Ghassami, Rasool Soltani
OBJECTIVE: Despite many attempts to treat leishmaniasis, new approaches are necessary to reduce the burden of disease. Perovskia abrotanoides (Brazambel) has shown significant effects against Leishmania parasites in some studies. This study aimed to investigate the effects of P. abrotanoides extract topical formulation on cutaneous leishmaniasis. METHODS: In this randomized controlled clinical trial, patients with cutaneous leishmaniasis were assigned to experimental ( n = 18) and control ( n = 18) groups...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38463189/performance-challenges-in-a-newly-established-clean-room-at-omid-hospital-isfahan-iran-a-descriptive-study
#6
JOURNAL ARTICLE
Mehrnaz Vaez, Mehran Sharifi, Sahar Karimi, Azadeh Moghaddas
OBJECTIVE: This study aimed to comprehensively assess the challenges faced by a newly established clean room in the oncology center of Omid Hospital, Isfahan, Iran, one of the first of its kind in the country. The research also sought to identify the underlying causes of these challenges and propose potential solutions to address them. METHODS: A 6-month cross-sectional study was conducted from December 2021 to May 2022. International guidelines such as British Columbia Cancer Agencies' guideline of hazardous drugs, the National Institute for Occupational Safety and Health guideline for working with hazardous drugs, and United States pharmacopeia related to cleanroom performance were studied, translated, and summarized into a checklist...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38463188/efficacy-of-an-herbal-preparation-atomy-s-hemohim-%C3%A2-against-ventilator-associated-pneumonia-a-randomized-controlled-clinical-trial
#7
JOURNAL ARTICLE
Ghazal Khamooshpour, Hossein Mahjubipour, Shadi Farsaei
OBJECTIVE: Despite the standard guideline recommendations to prevent ventilator-associated pneumonia (VAP), it has remained one of the common lung infections in the intensive care unit (ICU). This clinical trial was designed to evaluate the effect of HemoHIM® , a mixture of traditional Korean medicinal plants, on preventing VAP in ICU patients. METHODS: This randomized controlled clinical trial was conducted on mechanically ventilated adult ICU patients with a clinical pulmonary infection score of VAP ≤6 in the first 48 h of ventilation...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38463187/head-to-head-comparison-of-tazarotene-and-calcitriol-with-or-without-sequential-therapy-in-mild-to-moderate-psoriasis-a-randomized-open-label-study
#8
JOURNAL ARTICLE
Jaspreet Kaur Sidhu, Prithpal Singh Matreja, Ashwani Kumar Gupta, Amandeep Singh, Surjit Singh
OBJECTIVE: Psoriasis is an autoimmune disease that causes rapid turnover of skin cells. It is a chronic disease that affects a patient's quality of life significantly and frequently requires long-term treatment. The study on sequential therapy with tazarotene 0.1% and calcitriol 0.0003% has not been tried so far; hence, we designed this study to compare the safety and efficacy of sequential therapy with tazarotene 0.1% cream and calcitriol 0.0003% ointment versus monotherapy in mild-to-moderate stable plaque psoriasis (SPP)...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38463186/role-of-artificial-intelligence-in-anesthesia-revolutionizing-patient-safety-and-care
#9
JOURNAL ARTICLE
Ram Kumar Garg
No abstract text is available yet for this article.
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38463185/investigating-the-prevalence-of-contrast-associated-nephropathy-and-the-related-risk-factors-in-patients-undergoing-elective-angioplasty
#10
JOURNAL ARTICLE
Mehrnoush Dianatkhah, Samira Poursaeid, Ehsan Shirvani, Shirinsadat Badri
OBJECTIVE: Contrast-associated nephropathy (CAN) is a sudden decrease in kidney function following contrast media administration. Considering the importance of CAN in the patient's outcome and the high prevalence of this complication in cardiac catheterizing centers, this study was designed to investigate the prevalence and the related risk factors of CAN in patients undergoing angioplasty in Chamran Heart Hospital, Isfahan, Iran, from January 2022 to June 2022. METHODS: The inclusion criteria were adult patients above 18 admitted for elective percutaneous coronary intervention (PCI)...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38463184/comparing-sequential-organ-failure-assessment-score-acute-physiology-and-chronic-health-evaluation-ii-modified-acute-physiology-and-chronic-health-evaluation-ii-simplified-acute-physiology-score-ii-and-poisoning-severity-score-for-outcome-prediction-of-pesticide
#11
JOURNAL ARTICLE
Gholamali Dorooshi, Shiva Samsamshariat, Farzad Gheshlaghi, Shafeajafar Zoofaghari, Akbar Hasanzadeh, Saeed Abbasi, Nastaran Eizadi-Mood
OBJECTIVE: This study aimed to assess the severity of poisoning, various scoring systems, including Sequential Organ Failure Assessment (SOFA) score, acute physiology and chronic health evaluation II (APACHE II), Simplified Acute Physiology Score (SAPS II), Modified APACHE II, and poisoning severity score (PSS) were used. In this study, we compared the predictive value of these scoring systems on the outcome of pesticide-poisoned patients. METHODS: This is a cross-sectional study of pesticide-poisoned patients (140 patients) who were admitted to the intensive care unit (ICU) of Khorshid Hospital, Isfahan, Iran, between January 2015 and 2019...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38213607/assessing-the-presence-of-the-joint-commission-international-accreditation-requirements-in-western-saudi-arabia-hospital-pharmacies-a-cross-sectional-study
#12
JOURNAL ARTICLE
Ahmed Ibrahim Fathelrahman, Huda Abdullah Almalki, Hanan Rashad Bajunaid, Ghaidaa Khalid Al-Harthi, Manal Omar Aljuaid, Ruqayyah Yahya Majrashi, Mohammed Abdullah Alsuwat
OBJECTIVE: The Central Board of Accreditation for Healthcare Institutions (CBAHI) the national Saudi accreditation body accredited most hospitals in Saudi Arabia whereas, the Joint Commission International (JCI) a well-known international accreditation body accredited some hospitals. We assessed Western Saudi Arabia hospital pharmacists' knowledge, opinions, and observations about pharmacy-related JCI accreditation criteria needed for hospitals. METHODS: This was a cross-sectional survey-based study conducted among pharmacy personnel working in the Ministry of Health (MOH), Military, and private hospitals in the Makkah region in western Saudi Arabia...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38213606/prophylaxis-effect-of-metronidazole-vaginal-gel-in-decreasing-the-risk-of-surgical-site-infections-after-elective-hysterectomy
#13
JOURNAL ARTICLE
Fahimeh Sabet, Sara Ravan, Azar Danesh Shahraki
OBJECTIVE: Infections are an important cause of morbidity and mortality after hysterectomy. Here, we aimed to investigate and evaluate the beneficial effects of metronidazole vaginal gel on the rate of surgical site infections in women undergoing elective abdominal hysterectomy. METHODS: This is a randomized prospective, double-blind controlled clinical trial performed in 2020 in Isfahan on 108 candidates for elective hysterectomy. At the beginning of the study, we completed a checklist of the patient's characteristics (patient age, body mass index [BMI], and history of medical conditions such as diabetes, hypertension, anemia, and immune deficiency) and the cause of hysterectomy...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38213605/keep-away-from-children-s-reach-a-missing-link-of-pharmacy-practice-research
#14
JOURNAL ARTICLE
Mohammed Kanan
No abstract text is available yet for this article.
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38213604/toxicoepidemiology-of-phosphide-poisoning-in-the-central-part-of-iran
#15
JOURNAL ARTICLE
Nastaran Eizadi-Mood, Mahnaz Momenzadeh, Masoumeh Sadeghi, Ahmad Yaraghi, Ali Mohammad Sabzghabaee, Sam Alfred
OBJECTIVE: Aluminum phosphide (ALP) and zinc phosphide (ZnP) are toxic agrochemical pesticides, which are commonly used as an agent of self-harm in developing countries. Because of high toxicity of phosphides, we evaluated toxico-epidemiology ALP and ZnP poisoning in with respect to outcome. METHODS: We performed a cross-sectional study with retrospective chart review including the records for patients admitted due to phosphide poisoning (ALP, ZnP) in a poisoning referral center in Khorshid Hospital, affiliated with Isfahan University of Medial Sciences, Isfahan, Iran...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38213603/evaluation-of-current-community-pharmacist-practice-in-saudi-arabia-a-cross-sectional-study-from-patients-perspective-part-i
#16
JOURNAL ARTICLE
Abdulmajeed Bajuayfir, Mohammad Alhazmi, Omar Alshareef, Ahmed Rawas, Sumayyah Alsharif, Amal Almasoudi, Ejaz Cheema, Majid Ali
OBJECTIVE: This study aimed to evaluate the current practice of community pharmacists from patients' and pharmacists' perspectives in Saudi Arabia. This paper presents the patients' perspective. METHODS: A self-administered cross-sectional survey was developed to collect responses from patients in Saudi Arabia from February to April 2021. The questionnaire comprised several statements related to the best practice in community pharmacy. Patients' responses to each statement were scored using a 5-point Likert scale...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/38213602/influence-of-cigarette-smoking-habit-on-clozapine-to-norclozapine-ratio-in-male-patients
#17
JOURNAL ARTICLE
Roberto Lozano, Carina Bona
OBJECTIVE: This study aimed to evaluate the influence of cigarette smoking habit on the clozapine (CLZ)-to-norclozapine (norCLZ) ratio in male patients. METHODS: The sample consisted of plasma concentration of CLZ and norCLZ data set. The mean values of CLZ, norCLZ, and CLZ-to-norCLZ, between male patients who smoke versus nonsmokers were compared. FINDINGS: CLZ mean plasma level of 142 ± 80 ng/ml and 305 ± 159 ng/ml, norCLZ mean plasma level of 93 ± 72 ng/ml and 234 ± 62 ng/ml, and mean CLZ-to-norCLZ plasma level ratio of 2...
2023: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/37969618/efficacy-and-safety-of-topical-timolol-for-the-treatment-of-facial-angiofibroma-in-children-with-tuberous-sclerosis-complex
#18
JOURNAL ARTICLE
Mohammadreza Ghazavi, Sareh Taheri, Ali Mohammad Sabzghabaee, Negah Tavakolifard, Omid Yaghini, Gita Faghihi, Kimia Afshar, Bahareh Abtahi-Naeini
OBJECTIVE: This study aimed to assess the efficacy and safety of topical timolol in treating facial angiofibromas (FAs) in pediatric patients with tuberous sclerosis complex (TSC). METHODS: A prospective clinical trial was conducted involving 15 children diagnosed with TSC and presenting with FAs. The participants were administered topical timolol gel 0.5% twice daily. Prior to the intervention, the severity of FAs in each patient was evaluated using the FA severity index (FASI), which assessed erythema, size, and extent of lesions...
2022: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/37969617/parent-directed-use-of-over-the-counter-medications-and-complementary-and-alternative-medicine-therapies-among-pediatric-patients-a-cross-sectional-study
#19
JOURNAL ARTICLE
Shreyasi Seth, Ashok Kumar Dubey, Nidhi Maheshwari
OBJECTIVE: The use of over-the-counter (OTC) drugs and complementary and alternative medicines (CAM) as initial options by parents is common in the pediatric population. Despite the widespread use of parent-directed medication (PDM) among the pediatric population, we have scarce data in the Indian context. This study was done to assess the PDM practices and its determinants in the Indian population. METHODS: It was a descriptive cross-sectional study assessing a representative sample of 284 parents of pediatric patients visiting the pediatrics department of a tertiary care hospital...
2022: Journal of Research in Pharmacy Practice
https://read.qxmd.com/read/37969616/efficacy-and-safety-comparison-of-two-different-doses-of-dexamethasone-in-hospitalized-patients-with-covid-19-a-randomized-clinical-trial
#20
JOURNAL ARTICLE
Somayeh Sadeghi, Nima Arezoomandi, Marzieh Mollaei Ardestani, Mohammad Emami Ardestani, Farzin Ghiasi, Ziba Farajzadegan
OBJECTIVE: The current study aims to investigate high- versus low-dose dexamethasone administration to control the disease with minor complications. METHODS: The current multicentric randomized clinical trial was conducted on 119 patients with COVID-19 pneumonia and assigned into two groups of low-dose (8 mg daily intravenous dose for at least 7 days or until discharge) ( n = 61) versus high-dose dexamethasone (24 mg for 3 days followed by daily 8 mg for the at least 4 days later or until discharge) ( n = 58) during 2020-2021...
2022: Journal of Research in Pharmacy Practice
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