journal
https://read.qxmd.com/read/38025331/the-impact-of-propolis-on-clinical-manifestations-and-specific-ige-levels-against-salsola-in-perennial-allergic-rhinitis-patients
#41
JOURNAL ARTICLE
Farahzad Jabbari-Azad, Maryam Khoshkhui, Negar Khalighi, Mojgan Mohammadi, Maryam Emadzadeh, Mehraneh Movahedi Aliabadi
Objectives: Propolis has an anti-inflammatory effect induced by inhibiting cyclooxygenase, subsequent inhibition of prostaglandin and nitric oxide synthesis, reduction of inflammatory cytokines, and eventually immunosuppressive activity [1-3]. This study aims to evaluate the impact of propolis on clinical features and specific IgE levels against salsola in perennial allergic rhinitis patients. Methods: Thirty patients diagnosed with perennial allergic rhinitis with salsola-positive skin prick test were enrolled in this randomized controlled clinical trial and divided into two groups...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025330/case-report-challenges-in-the-diagnosis-of-eosinophilic-esophagitis
#42
JOURNAL ARTICLE
Jassim Ahmed Khan, Tayseer Ibrahim, Maryam Ali Al-Nesf
No abstract text is available yet for this article.
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025329/empiric-anti-giardia-therapy-in-non-diarrheal-protein-losing-enteropathy-a-focus-on-children-with-monogenic-humoral-immunodeficiency
#43
JOURNAL ARTICLE
Tariq Al Farsi, Khwater Ahmed, Nashet Al Sukaiti
Background and Aim: Chronic giardia infection can lead to non-erosive gastrointestinal disorders, including protein-losing enteropathy (PLE). This report describes non-diarrheal PLE in chronic giardiasis in children with defective humoral immunity. Methods: The retrospective report is related to 2 children known to have a monogenic inborn error of immunity. The first patient is a 13-year-old boy with X-linked agammaglobulinemia (Patient-1), and the second is a 5-year-old boy with NF-kB inducing kinase (NIK) deficiency infection...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025328/classification-of-common-variable-immunodeficiency-through-immunological-and-clinical-phenotyping-in-moroccan-patients
#44
JOURNAL ARTICLE
Khaoula Mokhantar, Abir Allaoui, Fatima Ailal, Jalila El Bakkouri, Kaoutar Ouazahrou, Abderrahmane Errami, Ahmed Aziz Bousfiha, Mina Moudatir
Objective: Common variable immunodeficiency (CVID) is a complex inborn error of humoral immunity with complications of both infectious and non-infectious origins. Classifications of CVID patients provide a clearer understanding of the pathogenesis, prediction, and management of non-infectious complications. This study aims to classify Moroccan CVID patients based on the European classification (EUROclass). Materials and Methods: We recruited 20 CVID patients meeting standard diagnostic criteria (5-6). After collecting clinical and demographic data, we used flow cytometry to analyze B-cell subsets and group patients and assess the relation of each group with clinical manifestations...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025327/the-combination-of-nasal-steroids-and-anti-leukotriene-to-reduce-adenectomy-in-children-with-osa-and-adenoid-hypertrophy
#45
JOURNAL ARTICLE
Manal Eldegeir, Noorah Al Marry, Fatima Awami, Fatima Alsada
BACKGROUND: Obstructive sleep apnea (OSA) affects 1% to 5% of all children, with the most significant prevalence between ages 2 and 8. Correlations between OSA and Adenoid hypertrophy (AH) have been well-demonstrated in children. If untreated, OSA can cause growth impairment, neuro-cognitive and behavioral problems, and cardiovascular complications. Allergy was reported to be a vital risk factor for AH, among other inflammatory processes mentioned. OBJECTIVES: To demonstrate that the combination of nasal steroids and ani leukotriene reduces the number of adenectomies in children with OSA and adenoid hypertrophy in Saudi children...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025326/the-incidence-of-depression-and-anxiety-disorders-in-spontaneous-chronic-urticaria-patients
#46
JOURNAL ARTICLE
Anushree Bangera, Meghna Singh, Kiran Godse, Sharmila Patil
Objective : A frequent condition known as chronic urticaria (CU) is characterized by the appearance of wheals, angioedema, or both. CU lowers the quality of life and may also result in psychological discomfort. The literature survey revealed few studies dealing with depression and anxiety in these patients. Hence, Hamilton scores for depression and anxiety were used in this study to evaluate the incidence of depression and anxiety in chronic urticaria patients. Methodology: To evaluate CU patients' levels of depression and anxiety, the Hamilton Rating Scale for Depression (HDRS) and the Hamilton Anxiety Rating Scale (HAMA) were applied...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025325/pityriasis-lichenoides-presented-with-skin-rash-mimicking-urticaria-a-case-report
#47
JOURNAL ARTICLE
Dalal Madawi, Hassan Mobayed
BACKGROUND: Acute urticaria is urticaria with or without angioedema that is present for less than six weeks, while chronic urticaria is present for more than six weeks. Pityriasis lichenoides (PL) is a benign cutaneous inflammatory disease of unknown etiology. Acute PL typically resolves within a few weeks, while chronic PL lasts several months. The skin rash of PL may resemble the rash of other conditions, so the distinction is essential and depends on history and physical examination and is confirmed by skin biopsy...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025324/impact-of-food-allergy-on-health-related-quality-of-life-a-case-report-of-2-patients-with-adult-onset-ige-mediated-food-allergy
#48
JOURNAL ARTICLE
Aqel Sami, Asaad Omer Imameldin, Tayseer Ibrahim
INTRODUCTION: Food allergy incidence is increasing, and reactions can be life-threatening. Food allergies significantly impact patients' and families' quality of life (QoL). Here, we describe two cases with adult-onset IgEmediated food allergy impacting their physical and psychological health and affecting their quality of life. CASE REPORT: Patient 1 : A 29-year-old lady, previously healthy, presented with a history of sneezing, shortness of breath, and eye and lip swelling shortly after drinking cow milk at the age of 28 years...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025323/vocal-cord-dysfunction-presented-as-difficult-to-control-asthma
#49
JOURNAL ARTICLE
Sara Mohamed, Hassan Mobayed
No abstract text is available yet for this article.
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025322/the-correlation-between-stress-response-term-babies-with-intrauterine-growth-restriction-and-adulthood-disease-theories
#50
JOURNAL ARTICLE
Manal Eldegeir, Cornelius Ani, Sally McGregor
BACKGROUND: Every year, 14 million babies are born with low birth weight (LBW) and/or intrauterine growth restriction (IUGR) in developing countries. In Sudan, 15-25% of all newborns are born with LBW, with half being Term-LBW. The importance of nutrition in the first 1000 days of life has been well demonstrated. Evidence links IUGR to various health and developmental disorders, and intrauterine programming of the hypothalamic-pituitary-adrenal (HPA) axis has been strongly suggested as a possible mechanism...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025321/the-profile-of-soluble-anti-antigen-antibodies-detected-by-immundot-experience-of-the-immunology-laboratory-university-hospital-hassan-ii-fez-morocco
#51
JOURNAL ARTICLE
Kaaouch Hanae, Ouboks Mohamed, El Mitri Ibrahim, Bhallil Ouahiba
Introduction: Soluble anti-antigen antibodies (Anti-ENA) represent a specificity of anti-nuclear autoantibodies (ANA), which are directed against nuclear particles composed of small RNA (Ribonucleic acid) and proteins. They are found during certain autoimmune diseases (ADs), most frequently during systemic lupus erythematosus (SLE) and Gougerot syndrome. The aim of this study is to retrospectively analyze the positive serum for Anti-ENA antibodies and associated pathologies. Materials and methods: This study was carried out at the Immunology Department, Central Laboratory of Medical Analysis, University Hospital Hassan II - Fez, Morocco, for a period of 2 years...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025320/the-effects-of-alpha-2a-and-beta-1a-interferons-on-the-coronavirus-disease-2019-prognosis
#52
JOURNAL ARTICLE
Ali Haghbin, Haniyeh Ghaffari-Nazari, Mohammad Reza Taghavi, Vida Vakili, Sahar Rastgou, Maryam Khoshkhui
BACKGROUND: The pandemic coronavirus disease 2019 (COVID-19) has been associated with substantial mortality worldwide. Efforts have continued to find an effective treatment for COVID-19. In vitro activity of interferon (IFN) subtypes has been shown against the SARS-CoV and MERS-CoV. Furthermore, the superiority of IFN- β over IFN- α 2b and IFN- α 2a has been demonstrated in MERS treatment. Early studies showed a low plasma level of IFNs in the peripheral blood or lungs of patients with severe COVID-19...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025319/efficacy-of-dupilumab-in-severe-atopic-dermatitis-ad-using-the-ad-control-tool-adct-score-in-the-population-of-qatar
#53
JOURNAL ARTICLE
Febu Joy, Sara AlKhawaga, Maryam Iqneibi, Fahad Al Marri, Radi Al Chalabi, Joerg Buddenkotte, Martin Steinhoff
Atopic Dermatitis (AD) is a high-burden disease that affects approximately 2-5% of adults. AD patients experience intense pruritus and often report sleep and mental health disturbances accompanied by a diminished quality of life. The patients' perceptions of their treatment benefits are becoming increasingly important in the benefit/risk assessment of therapeutics such as the gold standard in AD therapy, Dupilumab. A survey questionnaire (ADCT) has been recently developed to assess the control of AD symptoms using subjective patient-based reporting only...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025318/association-between-breastfeeding-and-prevalence-of-allergies-among-children-in-the-academy-teaching-charity-hospital-sudan
#54
JOURNAL ARTICLE
Maab Kamaledlin Mohammedali Mohammed Abouda, Rabih Berair
Background: The role of breastfeeding in the primary prevention of allergic diseases remains controversial, with hardly any reported studies from developing countries. Objective: To evaluate the association between breastfeeding and the presence of allergies. Specifically, we aimed to demonstrate the association between the exclusivity of breastfeeding and the prevalence of allergies, including asthma, eczema, allergic rhinitis, and food allergy. Secondly, to ascertain the impact of feeding cow milk as complimentary feeding on the prevalence of atopy...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025317/immunomodulatory-potential-of-anti-ifn-beta-antibodies-on-monocyte-derived-macrophages
#55
JOURNAL ARTICLE
Ajith Sominanda, Til Menge, Hans Peter Hartung, Bernd C Kieseier
Introduction: Multiple sclerosis (MS) is a disabling neurological disease with an unknown etiology, where the recombinant interferon beta (rIFNβ) is the most established treatment. However, the development of anti-IFNβ antibodies has posed a significant therapeutic drawback. In this study, the interaction between anti-IFNβ antibodies and macrophages was investigated to assess the effects on the immune system. Methodology: Using magnetic beads, anti-IFNβ antibodies were extracted from MS patients' sera positive for anti-IFNβ antibodies...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025316/heparin-induced-anaphylaxis-shock
#56
JOURNAL ARTICLE
Anas Mohamed, Amro Abdelrahman, Khalid Y Fadul, Mohamed Elgassim
Introduction: Anaphylaxis is a fatal condition that can be easily managed if discovered early. Only a few examples of anaphylaxis-like reactions caused by heparin have been documented, and immediate-type hypersensitivity reactions to heparin are extremely uncommon. Case Presentation: We report a case of a 53-yearold gentleman known to have an End Stage Renal Disease (ESRD) on Hemodialysis for two years, who went to the dialysis facility in his usual state of health. After two hours of dialysis, a new lock of taurolidine/heparin was installed; one minute later, the patient started to vomit and became restless, blood pressure dropped to 60/47 mmHg, and urticarial hives and a reddish rash developed on his skin, covering his trunk and limbs...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025315/aeroallergens-sensitization-pattern-in-atopic-patients-in-qatar-a-retrospective-study
#57
JOURNAL ARTICLE
Sherin Thalappil, Tayseer Ibrahim, Sibi Shibu, Hassan Mobayed, Maryam Al-Nesf
BACKGROUND: Allergic respiratory diseases (allergic rhinitis and asthma) are major health problems with high prevalence causing significant patient morbidity as well as an economic burden (1). Sensitization to inhaled allergens is a major factor in the pathogenesis of allergic respiratory diseases (2). This study aims to determine the commonest aeroallergen sensitization in patients with allergic symptoms who attended an Adult Allergy Clinic in Qatar. METHODS: This retrospective study reviewed the skin prick test results database of 20 aeroallergens performed between January 1st to December 31st , 2022, at an Adult Allergy clinic in Qatar...
2023: Qatar Medical Journal
https://read.qxmd.com/read/38025314/a-case-of-familial-mediterranean-fever-presented-with-recurrent-infection
#58
JOURNAL ARTICLE
Marzieh Tavakol, Matineh Nirouei
INTRODUCTION: The periodic fever syndrome Familial Mediterranean Fever (FMF) is caused by mutations in MEFV, which promote inflammation and present with uncontrolled systemic and organ-specific inflammation that can resemble infectious conditions. It is diagnosed based on clinical criteria, including frequent symptoms such as abdominal and thoracic pain, family history, and response to treatment with colchicine, which is confirmed by genetic assessment. Herein, we present a case of FMF with a relatively uncommon presentation...
2023: Qatar Medical Journal
https://read.qxmd.com/read/37936885/injuries-related-to-pets-exotic-animals-and-falconry-in-qatar
#59
JOURNAL ARTICLE
Suha Turkmen, Guillaume Alinier, Amr Mohammed Elmoheen, Alamgir Ahmed Qureshi, Benny Remi Ponappan, Mohamed Bahgat, Rashid Khan, Aftab Azad
INTRODUCTION: Pets and exotic animals are increasingly popular all over the world. Some of these animals may cause injuries to their owners or other people during interactions. Both injuries and systemic infections always present diagnosis and treatment challenges. Emergency physicians´ clinical experience in managing patients with injuries caused by pets and exotic animals, in particular, is limited; hence, we believe that it is a domain to explore in a Middle Eastern country to help raise awareness and provide reminders as to the best evidence-based medical practice...
2023: Qatar Medical Journal
https://read.qxmd.com/read/37920783/covid-19-associated-neurological-sequelae-a-case-series-on-cerebral-microbleeds-and-encephalopathy
#60
Abeer Sabry Safan, Yahia Imam, Mohamad Y Khatib, Mohammad Al Wraidat, Mohammad M Altermanini, Salah A Al-Mughalles, Anood Al-Assaf, Mariam Olish, Moustafa S Elshafei, Abdulqadir J Nashwan
BACKGROUND: Critical illness-associated cerebral microbleeds and leukoencephalopathy connected to coronavirus disease 2019 (COVID-19) infection are emerging areas of concern in current medical literature. METHODS: We reviewed cases of patients with COVID-19-associated neurological manifestations to study the prevalence and outcome of such conditions. Case Series Findings: Our review yielded seven distinct patients. Six exhibited cerebral microbleeds, primarily localized in the juxtacortical white matter and the corpus callosum...
2023: Qatar Medical Journal
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