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United European Gastroenterology Journal

Julien Kirchgesner, Benjamin Misselwitz
No abstract text is available yet for this article.
December 2018: United European Gastroenterology Journal
Vikram Rangan, Mohammed Zakari, William Hirsch, Sarah Ballou, Prashant Singh, Thomas Sommers, Johanna Iturrino, Judy Nee, Kyle Staller, Anthony Lembo
Background: A subset of patients with functional defecation disorders have predominance of the puborectalis muscle (PRM) on three-dimensional high definition anorectal manometry (HDARM), known as paradoxical puborectalis syndrome (PPS). The aim of this study was to assess clinical and manometric differences between patients with and without PPS. Methods: A total of 227 women with functional defecation disorders undergoing HDARM between December 2012 and October 2016 at a single center were included in this study...
December 2018: United European Gastroenterology Journal
Heithem Soliman, Bertrand Brieau, Marie-Anne Guillaumot, Sarah Leblanc, Maximilien Barret, Marine Camus, Marie Dior, Benoit Terris, Romain Coriat, Frédéric Prat, Stanislas Chaussade
Background: Laterally spreading tumours are separated in subclasses: granular, homogenous or nodular mixed; and non-granular, flat or pseudodepressed. For every subtype, a proper risk of submucosal invasive cancer has been described in Asian series. Objective: The aim of the study was to determine the rate of cancer and submucosal invasive cancer in a Western series of endoscopic-resected laterally spreading tumours and their endoscopic predictive factors. Methods: A total of 374 laterally spreading tumours ≥20 mm were resected by endoscopy in our single centre between 2012-2016...
December 2018: United European Gastroenterology Journal
Maria Magdalena Buijs, Rasmus Kroijer, Morten Kobaek-Larsen, Cristiano Spada, Ignacio Fernandez-Urien, Robert Jc Steele, Gunnar Baatrup
Background: Colon capsule endoscopy is a promising technique for evaluation of the colon, but its reproducibility is still unknown. Objective: This study assesses intra and inter-observer agreement in evaluations of colon capsule endoscopy videos. Methods: Forty-two complete colon capsule endoscopy investigations were analysed by three experts and two beginners. Intra-observer agreement was assessed in paired readings of two experts and two beginners...
December 2018: United European Gastroenterology Journal
Mary Hussey, Grainne Holleran, Roisin Stack, Neil Moran, Claudio Tersaruolo, Deirdre McNamara
Background: Same-day colon capsule endoscopy (CCE) immediately following incomplete optical colonoscopy (OC) would have a number of advantages for patients, while also presenting unique procedural challenges including the effect of sedation on capsule propulsion and patient tolerance of protracted preparation and fasting. Aim: The aim of this article is to prospectively assess the efficacy of same-day CCE after incomplete OC in an unselected patient cohort. Methods: This was an observational, prospective, single-centre study of CCE post-incomplete colonoscopies...
December 2018: United European Gastroenterology Journal
Hiroaki Minamino, Yasuaki Nagami, Masatsugu Shiba, Kappei Hayashi, Taishi Sakai, Masaki Ominami, Shusei Fukunaga, Tsuyoshi Hayakawa, Kazuki Aomatsu, Satoshi Sugimori, Tetsuya Tanigawa, Hirokazu Yamagami, Toshio Watanabe, Yasuhiro Fujiwara
Background: Incomplete polyp resection during colorectal endoscopic mucosal resection (EMR) might contribute to the development of interval cancer. Objective: This retrospective study aimed to determine the incidence of incomplete polyp resection during EMR of colorectal polyps located across a fold compared with that of colorectal polyps located between folds. Methods: In total, 262 patients with 262 lesions that were ≥10 mm in diameter and treated with conventional EMR were enrolled...
December 2018: United European Gastroenterology Journal
Jarek Kobiela, Paulina Wieszczy, Jarosław Reguła, Michał F Kamiński
Background and aims: Obesity is associated with an increased incidence of and mortality from colorectal cancer (CRC). Screening colonoscopy seems particularly important for individuals with obesity. The aim of this study is to analyse the characteristics of screening colonoscopy in individuals with obesity. Methods: We performed a cross-sectional analysis of records of 75,278 patients from a national colonoscopy screening programme in Poland. The database contained demographic data, colonoscopy results, self-reported data on weight and height, a standardized screenees' experience questionnaire and colorectal findings...
December 2018: United European Gastroenterology Journal
Laura Carot, Antoni Castells, Cristina Hernández, Cristina Alvarez-Urturi, Francesc Balaguer, Angel Lanas, Joaquín Cubiella, Jose D Tasende, Rodrigo Jover, Vicent Hernandez, Fernando Carballo, Luis Bujanda, Enrique Quintero, Montserrat Andreu, Xavier Bessa
Background: The diagnostic yield of the faecal immunochemical test and sigmoidoscopy in detecting proximal serrated polyps in a colorectal cancer screening programme has not been fully assessed. Aim: We determined the detection rate of proximal serrated polyps by simulated sigmoidoscopy and faecal immunochemical test compared with total colonoscopy in a population-based, multicentre, nationwide, randomised controlled trial (ColonPrev study). Methods: Sigmoidoscopy yield was simulated based on the UK-Flexible Sigmoidoscopy Trial for total colonoscopy referral...
December 2018: United European Gastroenterology Journal
Qibin He, Lei Wang, Chunyan Peng, Xiaoping Zou, Qiang Zhan, Yaping Xu, Qiang Liu, Junbo Qian, Lei Gong, Yingzhou Shen, Jianping Chen
Background and objectives: Prophylactic pancreatic duct stent placement effectively reduces post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients, but the optimal stent remains unclear. We modified a 5-Fr, 3 cm pancreatic stent by removing the flange on the pancreatic side and compared the rate of spontaneous dislodgement and complications with the ordinary stent. Methods: This was a randomized controlled trial at six tertiary endoscopic centers...
December 2018: United European Gastroenterology Journal
Robert A Moran, Guillermo García-Rayado, Daniel de la Iglesia-García, Emma Martínez-Moneo, Esther Fort-Martorell, Eugenia Lauret-Braña, Mar Concepción-Martín, Fabio Ausania, Carlos Prieto-Martínez, Miguel González-de-Cabo, Noé Quesada-Vázquez, M Asunción Marcaide-Ruiz-de-Apodaca, José A Pajares-Díaz, Francia C Díaz, José L de-Benito, Jennifer Hinojosa-Guadix, Pilar Marqués-García, Jaume Boadas, Eduardo Bajador-Andreu, Oswaldo Moreno, Federico Argüelles-Arias, Gregorio Martín-Benítez, Carla Tafur-Sánchez, Jesús Leal-Téllez, Beatriz Romero-Mosquera, Ruben Hernaez, Georgios I Papachristou, Vikesh K Singh, Enrique de-Madaria
Background: There are few large prospective cohort studies evaluating predictors of outcomes in acute pancreatitis. Objectives: The purpose of this study was to determine the role of age and co-morbid disease in predicting major outcomes in acute pancreatitis. Methods: Data points were collected according to a predefined electronic data collection form. Acute pancreatitis and its complications were defined according to the revised Atlanta classification...
December 2018: United European Gastroenterology Journal
Monika Rau, Ateequr Rehman, Marcus Dittrich, Albert K Groen, Heike M Hermanns, Florian Seyfried, Niklas Beyersdorf, Thomas Dandekar, Philip Rosenstiel, Andreas Geier
Background: Intestinal microbiota and their metabolites (e.g. short-chain fatty acids (SCFAs)) may influence nonalcoholic fatty liver disease (NAFLD). Objective: The objective of this article is to analyze gut bacterial diversity together with fecal SCFA concentrations and immunophenotyping of peripheral blood in histology-proven NAFLD patients. Methods: Thirty-two NAFLD patients (14 nonalcoholic fatty liver (NAFL), 18 nonalcoholic steatohepatitis (NASH)) and 27 healthy controls (HCs)) were included in this study...
December 2018: United European Gastroenterology Journal
Tom van Gils, Petula Nijeboer, Lucy Ih Overbeek, Michael Hauptmann, Daan Ar Castelijn, Gerd Bouma, Chris Jj Mulder, Flora E van Leeuwen, Daphne de Jong
Background: The association between celiac disease (CD) and the development of lymphoid and gastrointestinal (GI) malignancies have been reported. However, data are scarce yet needed to develop evidence-based follow-up programs. Objective: The objective of this article is to assess relative (RR) and absolute risks of lymphoma and GI carcinoma for newly diagnosed patients. Methods: A case-control design to determine RR was performed with cases (lymphoma or GI carcinoma) and controls (melanoma or basal cell carcinoma) diagnosed 1994-2014, retrieved from the Dutch nationwide population-based pathology database (PALGA)...
December 2018: United European Gastroenterology Journal
Louise B Grode, Inge E Agerholm, Peter Humaidan, Tina Parkner, Bodil H Bech, Cecilia H Ramlau-Hansen, Thomas M Jensen
Background: Coeliac disease is an autoimmune disease triggered by dietary gluten and has been associated with several conditions influencing female and male reproduction. Due to unspecific symptoms, coeliac disease can be unrecognised for years. Objective: To estimate the prevalence of unrecognised coeliac disease among couples referred to fertility treatment. Methods: Cross-sectional screening for coeliac disease in men and women referred to fertility treatment using IgA tissue transglutaminase antibodies as a marker of coeliac disease and small-bowel biopsies to confirm the diagnosis...
December 2018: United European Gastroenterology Journal
Dolores Sgambato, Giulio Visciola, Emanuele Ferrante, Agnese Miranda, Lorenzo Romano, Concetta Tuccillo, Francesco Manguso, Marco Romano
Background: Helicobacter pylori is transmitted through faecal-oral or oral-oral routes. Whether H. pylori infection is more prevalent in sexual partners of H. pylori -infected subjects is unclear. Objective: We evaluated 1) the prevalence of H. pylori infection in sexual partners of H. pylori- infected subjects; and 2) whether presence of gastroesophageal reflux in H. pylori -infected subjects was associated with transmission of infection to their sexual partners...
December 2018: United European Gastroenterology Journal
Axel Josefsson, Olafur Palsson, Magnus Simrén, Ami D Sperber, Hans Törnblom, William Whitehead
Background: The prevalence and frequency of oesophageal symptoms suggestive of a functional oesophageal disorder according to the Rome IV criteria are unknown. Objective: We aimed to describe the prevalence and risk factors for oesophageal symptoms compatible with functional oesophageal disorders in the general population. Methods: Data were analysed from a population-based online survey of 6300 individuals aged ≥ 18 years in the USA, UK and Canada with equal demographic proportions across countries...
December 2018: United European Gastroenterology Journal
Dirk Domagk, Kofi W Oppong, Lars Aabakken, Laszlo Czakó, Tibor Gyökeres, Gianpiero Manes, Peter Meier, Jan-Werner Poley, Thierry Ponchon, Andrea Tringali, Cristina Bellisario, Silvia Minozzi, Carlo Senore, Cathy Bennett, Michael Bretthauer, Cesare Hassan, Michal F Kaminski, Mario Dinis-Ribeiro, Colin J Rees, Cristiano Spada, Roland Valori, Raf Bisschops, Matthew D Rutter
The European Society of Gastrointestinal Endoscopy (ESGE) and United European Gastroenterology present a short list of key performance measures for endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP). We recommend that endoscopy services across Europe adopt the following seven key and one minor performance measures for EUS and ERCP, for measurement and evaluation in daily practice at centre and endoscopist level: 1 Adequate antibiotic prophylaxis before ERCP (key performance measure, at least 90%); 2 antibiotic prophylaxis before EUS-guided puncture of cystic lesions (key performance measure, at least 95%); 3 bile duct cannulation rate (key performance measure, at least 90%); 4 tissue sampling during EUS (key performance measure, at least 85%); 5 appropriate stent placement in patients with biliary obstruction below the hilum (key performance measure, at least 95%); 6 bile duct stone extraction (key performance measure, at least 90%); 7 post-ERCP pancreatitis (key performance measure, less than 10%); and 8 adequate documentation of EUS landmarks (minor performance measure, at least 90%)...
December 2018: United European Gastroenterology Journal
Jan Tack
No abstract text is available yet for this article.
December 2018: United European Gastroenterology Journal
Grainne Holleran, Axel Dignass
No abstract text is available yet for this article.
November 2018: United European Gastroenterology Journal
Charles Murray
No abstract text is available yet for this article.
November 2018: United European Gastroenterology Journal
A G Gravina, N Prevete, C Tuccillo, C De Musis, L Romano, A Federico, A de Paulis, G D'Argenio, M Romano
Background and aims: Hp(2-20), a Helicobacter pylori- derived peptide interacting with N-formyl peptide receptors (FPRs), accelerates the healing of gastric injury in rats. Whether Hp(2-20) affects the recovery of inflamed colonic mucosa is unknown. We evaluated whether Hp(2-20) accelerated the healing of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis and explored the mechanism(s) underlying any such effect. Methods: Fifteen rats underwent rectal administration of Hp(2-20) 250-500 µg/kg/day, or of its control peptide Hp1 for 10 days, following induction of colitis with TNBS...
November 2018: United European Gastroenterology Journal
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