journal
https://read.qxmd.com/read/36385747/disseminated-mycobacterium-tuberculosis-and-iga-nephropathy
#21
Gordon Audley, Bianca Davidson, Erika Jones, Brendon Price, Brian Rayner, Nicola Wearne, Zibya Barday
Mycobacterium tuberculosis (MTB) is an under-recognised cause of genitourinary disease. IgA nephropathy (IgAN), a leading cause of glomerulonephritis worldwide, has been described as a rare consequence of disseminated MTB infection. In this case report, we present the first case of MTB associated IgAN in Africa. Finding IgAN on kidney biopsy in an MTB endemic area should prompt a thorough investigation for MTB to increase the chance of remission of IgAN and prevent inappropriate use of immunosuppression.
2022: Case Reports in Nephrology
https://read.qxmd.com/read/36312462/an-exceptional-case-of-light-chain-only-variant-of-proliferative-glomerulonephritis-with-monoclonal-immunoglobulin-deposits-secondary-to-chronic-lymphocytic-leukemia-a-case-report-and-review-of-the-literature
#22
José C De La Flor, Jacqueline Apaza, Francisco Díaz, Edna Sandoval, Tania Linares, Alexander Marschall, Patricia Núñez, Andrea Cecilia Rivas-Nieto, Elisa Ruiz
We present the case of an 86-year-old Caucasian male with an 11-year history of low-grade chronic lymphocytic leukemia (CLL) presenting with nephrotic syndrome (NS). Renal biopsy findings showed a diffuse mesangial and endocapillary proliferative glomerulonephritis (GN) lesion with fine granular deposits, consistent with a rare morphologic variant of proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID)-lambda light chain (LC) only. Monthly combination therapy of rituximab (500 mg/m2 on day 1), fludarabine (30 mg/m2 on days 1-3), and cyclophosphamide (750 mg/m2 on days 1-3) was administered...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/36284565/cell-free-and-concentrated-ascites-reinfusion-therapy-during-hemodialysis-for-intradialytic-hypotension-and-intractable-ascites
#23
Hideyuki Hayasaka, Kiyonori Ito, Susumu Ookawara, Masaya Kofuji, Takayuki Uchida, Shunto Kawamura, Ayumi Gomyo, Haruhisa Miyazawa, Yuichiro Ueda, Keiji Hirai, Shun-Ichi Kimura, Naoki Momose, Shinichi Kako, Yoshiyuki Morishita
A 60-year-old woman with POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome and intractable ascites presented with acute renal failure and received hemodialysis (HD) therapy. Due to frequent intradialytic hypotension, ultrafiltration with cell-free and concentrated ascites reinfusion therapy (CART) was performed to adequately manage the body fluid status and massive ascites. During HD with CART, her blood pressure was maintained compared with that during HD without CART, and an ultrafiltration volume of 3...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/36274908/langerhans-cell-histiocytosis-manifests-with-acute-severe-hypernatremia-during-hospitalization
#24
Kullaya Takkavatakarn, Hansamon Poparn, Pisut Katavetin
Central diabetes insipidus (DI) is characterized by a deficiency in arginine vasopressin (AVP), an antidiuretic hormone leading to excessive free water loss in the urine and hypernatremia. Central DI can be the first presentation of several occult diseases. However, patients with central DI who have functioning thirst mechanisms and access to water may initially exhibit normal sodium levels. We report a 57-year-old woman who was admitted to the hospital due to cholangitis. Her initial serum sodium was normal and she rapidly developed severe hypernatremia after fluid restriction...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/36213871/concomitant-nephrotic-syndrome-and-cryoglobulinemia-in-a-case-of-malignant-mesothelioma
#25
Kei Nagai, Hiroaki Tachi, Kohei Inoue, Atsushi Ueda
Malignant pleural mesothelioma is rarely associated with nephrotic syndrome. Cryoglobulinemia is found in various pathological statuses, such as hepatitis C virus infection but rarely in malignant neoplasms. We recently encountered a patient with malignant mesothelioma coincident with nephrotic syndrome and cryoglobulinemia in the course of chemotherapy. A 60-year-old man employed as a building painter was diagnosed with malignant mesothelioma by lung biopsy two years earlier and was started on chemotherapy...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/36200067/a-rare-case-of-extensive-eggshell-intestinal-wall-peritoneal-calcification-in-a-long-term-continuous-peritoneal-dialysis-patient
#26
Erasmia Sampani, Chrysostomos Dimitriadis, Efstratios Kasimatis, Evangelos Memmos, Aikaterini Papagianni
Encapsulating peritoneal sclerosis (EPS) is a rare but rather serious complication of long-term peritoneal dialysis. The etiology of EPS is multifactorial, with long-term peritoneal dialysis, multiple peritonitis episodes, and uncontrolled hyperparathyroidism considered to be major risk factors for this often life-threatening condition. We report a case of a 55-year-old female patient with Down syndrome and end-stage renal disease (ESRD) on long-term peritoneal dialysis (PD) with extensive intestinal peritoneal calcifications and a rather uncomplicated long follow-up...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/36124007/renal-involvement-of-cd20-negative-intravascular-large-b-cell-lymphoma-with-neurological-manifestations
#27
Faten Aqeel, Serena M Bagnasco, Duvuru Geetha
The involvement of hematological tumors such as lymphoma in the kidneys is a well-recognized phenomenon. Some of the distinct reported pathological processes resulting in kidney dysfunction include minimal change disease, lymphocytic invasion of the parenchyma, immune complex disposition, immunotactoid glomerulopathy, membranous glomerulopathy, and acute tubular injury. We report a rare case of CD20-negative intravascular lymphoma found on a kidney biopsy in a male with primary angiitis of the central nervous system (CNS) who presented with acute kidney injury and proteinuria...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/36082137/spontaneous-retroperitoneal-bleeding-as-a-complication-of-unusual-renal-paraganglioma
#28
Tawfeeq I Sangey, Hamim Abdul Rusheke, Ansaar I Sangey, Nimishkumar Chaya, Advera Ngaiza
Spontaneous retroperitoneal bleeding is a rare occurrence that might have catastrophic implications. We present a 58-year-old male with a 4-day history of progressively worsening left-sided flank pain due to retroperitoneal hemorrhage from a nonfunctional renal paraganglioma. Abdominal contrast CT scan was helpful in locating the tumor, estimating tumor size and extent of bleeding, visualizing the interaction between the tumor and the surroundings, and ruling out any potential metastasis; however, it lacked specificity in identifying the origin of the mass, needing histologic investigation for a conclusive diagnosis...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/36065409/a-case-of-paediatric-anti-glomerular-basement-membrane-disease-associated-with-thrombotic-thrombocytopenic-purpura
#29
Joseph McAllister, Pradeep Nagisetty, Kay Tyerman
Anti-GBM disease is a rare vasculitis that causes rapid progressive glomerulonephritis and pulmonary haemorrhage. It is usually an adult diagnosis with isolated paediatric cases reported. Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy mainly affecting adults that causes multiorgan ischaemia, microangiopathic haemolytic anaemia, and thrombocytopenia. We present the first paediatric case of concurrent anti-GBM disease and TTP. A 14-year-old boy presented with acute kidney failure and severe pulmonary haemorrhage due to anti-GBM disease, confirmed on auto-antibody testing...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/36046257/gadolinium-induced-acute-graft-pancreatitis-in-a-simultaneous-pancreas-kidney-transplant-recipient
#30
Chiang Sheng Lee, Rachel Yi Ping Tan, Nitesh N Rao
Gadolinium-induced acute pancreatitis is a rare phenomenon associated with the administration of gadolinium-based contrast agents. Only five cases of gadolinium-induced acute pancreatitis have been reported worldwide in patients with native pancreas and none with a pancreatic graft. We present a 32-year-old woman with prior history of simultaneous pancreas-kidney transplant who presented with generalized abdominal pain associated with systemic inflammatory response syndrome requiring admission to the intensive care unit...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/36032631/ten-cases-of-biopsy-proven-acute-tubulointerstitial-nephritis-report-from-a-single-center-in-a-rural-area-from-2008-to-2021
#31
Kei Nagai, Tsuyoshi Tsukada, Akiko Sakata, Atsushi Ueda
Acute tubulointerstitial nephritis (ATIN) can be caused by any number of factors, and it accounts for several percent of renal biopsy cases. In Japan, case reports exist, but there are few single-center series of ATIN cases. Case 1 . A teenage male patient developed fever and cough on day X-61 and was found to have normal renal function and positive C-reactive protein (CRP) by his primary care physician. On day X-20, he presented with cough and nasal discharge in addition to low-grade fever, and his doctor noted renal dysfunction with serum creatinine of 2...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/35910259/renal-mucormycosis-post-covid-19-infection-presenting-as-unilateral-hydronephrosis-in-a-young-immunocompetent-male
#32
Rabin Nepali, Shreya Shrivastav, Dibya Singh Shah
Mucormycosis is a rare invasive fungal infection with a high mortality rate caused by members of the family Mucoraceae. It mainly affects immunocompromised hosts such as poorly controlled diabetes mellitus, previous solid organ transplant, high-dose steroids, and hematologic malignancy. The most common sites of the disease are rhinocerebral, the skin, the lungs, and the gastrointestinal tract. In this era of COVID-19 infection, there has been a significant rise in invasive mucormycosis predominantly reported from southeast...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/35910258/a-case-of-oxalate-nephropathy-in-a-known-diabetic-patient-following-acute-alcoholic-pancreatitis
#33
John Odhiambo, Hanika Patel, Anderson Mutuiri, Fazal Yakub, Ahmed Sokwala
This was a case of a 39-year-old gentleman known to have diabetes mellitus since February 2021 on insulin glargine (Lantus) 16 units nocte and sitagliptin/metformin 50/500 mg once a day who presented to a tertiary teaching hospital in Kenya in May 2021 with a three-week history of vomiting and diarrhea. He had been previously admitted to a different facility with acute alcoholic pancreatitis. His examination was nonremarkable except for mild dehydration and pallor. He had moderate metabolic acidosis and deranged renal function...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/35859789/a-patient-with-siadh-urinary-retention-constipation-and-bell-s-palsy-following-a-tick-bite
#34
Mariana Leone, Anwar Iqbal, J R Hugo Bonatti, Samina Anwar, Catherine Feaga
Introduction . Lyme disease is the most common vector borne disease in the USA caused by the bacterium Borrelia burgdorferi. If untreated, Lyme disease can cause a variety of secondary symptoms often difficult to interpret. Some of the rare manifestations of Lyme disease include SIADH-like syndrome, enteroparesis, and urinary retention. Case Report . A 69-year-old male presented with anorexia and constipation and was found to have hyponatremia. Several days after admission, Bell's palsy developed and he experienced urinary retention requiring catheterization...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/35813243/iatrogenic-infective-endocarditis-in-hemodialysis-patients-a-case-report-and-review-of-the-literature
#35
Ali Oullaï, Edouard Cubilier, Mohamed Tayeb Salaouatchi, Maxime Taghavi, Yasmin Zouggari, Joëlle Nortier, Maria Do Carmo Filomena Mesquita
Foreign bodies such as implanted cardiac devices are susceptible to infections and may be involved in infective endocarditis. Exposure to pathogens, by frequent use of intravascular accesses for hemodialysis (i.e., catheters or fistulas), combined with high rates of degenerative heart valve diseases in hemodialysis patients, both favor the development of infective endocarditis in this population. The mitral and aortic valves are predominantly implicated in endocardial infections. The involvement of both mitral and tricuspid valves is rare in the general population but can occur in hemodialysis patients with implanted cardiac devices...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/35782521/crescentic-glomerulonephritis-and-membranous-nephropathy-a-rare-overlap
#36
Mohamedanwar Ghandour, Heba Osman, Samer Alkassis, Alix Charles, Kristina Zalewski, Jarrett Weinberger, Yahya Malik-Osman, Zeenat Y Bhat
BACKGROUND: Membranous nephropathy (MN) is a disease that affects the basement membrane of the glomeruli of the kidney resulting in proteinuria. The concurrent incidence of vasculitic glomerulonephritis and MN in the same patient is unusual. Herein, we report a case with this unusual combination. CASE: Our patient is a 53-year-old Hispanic male with a medical history of tobacco use, type 2 diabetes mellitus, and hypertension who presented with hematuria and was found to have nephrotic range proteinuria and renal impairment...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/35720957/calciphylaxis-a-long-road-to-cure-with-a-multidisciplinary-and-multimodal-approach
#37
Vasiliki Zoi, Dimitra Bacharaki, Aggeliki Sardeli, Minas Karagiannis, Sophia Lionaki
Calciphylaxis is a rare yet potentially fatal condition, resulting from ectopic calcification of the small arterioles of the dermis with resulting necrotic lesions infection, sepsis, and death. In hemodialysis patients, its prevalence ranges between 1 and 4%, while mortality amounts to 30-80%. We present in here a 45-year-old female on chronic dialysis with morbid obesity, who was admitted for painful nodules in the lower abdomen and necrotic lesions at the lower extremities. Severe uremia and uncontrolled secondary hyperparathyroidism were the main characteristics in this patient, and thus, a clinical diagnosis of calciphylaxis was made...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/35676927/an-unusual-case-of-kidney-injury-in-a-young-woman-with-a-connective-tissue-disease
#38
Roberto Rivera, Salvador Vila
A 32-year-old female was admitted to our institution with thrombocytopenia, fever, serositis, hepatosplenomegaly, diffuse lymphadenopathy, and renal insufficiency. A diagnosis of systemic lupus erythematosus was made. Due to recalcitrant thrombocytopenia, serositis, and renal insufficiency methylprednisolone was prescribed in high doses. In addition to proteinuria and hematuria, she was found to have uric acid crystals in her urinalysis. A serum uric acid was found elevated at 18 mg/dL. Rasburicase infusions were started...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/35573079/anca-negative-vasculitis-in-eosinophilic-granulomatosis-with-polyangiitis-complicated-with-membranous-nephropathy-a-case-report-and-brief-literature-review
#39
Eri Kasama, Jun Ino, Fumika Iemura, Saeko Kumon, Mio Kodama, Keitaro Sato, Hitoshi Eizumi, Kosaku Nitta, Junichi Hoshino
Renal involvement in eosinophilic granulomatosis with polyangiitis (EGPA) typically occurs in anti-neutrophil cytoplasmic autoantibody (ANCA)-positive cases presenting with rapidly progressive renal insufficiency and urinary abnormalities induced by primarily necrotizing crescentic glomerulonephritis (NCGN). Recently, ANCA-negative EGPA has also been reported to manifest with renal involvement, such as NCGN or non-NCGN, including membranous nephropathy (MN). Herein, we report a 70-year-old female who presented with purpura on the lower legs, upper limb numbness, renal dysfunction (eGFR, 20...
2022: Case Reports in Nephrology
https://read.qxmd.com/read/35558565/exacerbation-of-congenital-hydronephrosis-as-the-first-presentation-of-covid-19-infection-in-children
#40
Masoumeh Mohkam, Mahnaz Jamee, Farshid Kompani, Mitra Khalili, Atena Seifi, Leily Mohajerzadeh
Background: Congenital hydronephrosis is one of the most common abnormalities of the upper urinary tract, which can be exacerbated by a variety of intrinsic or extrinsic triggers. The urinary tract system is one of the major organs complicated by COVID-19 infection. Case Presentations . Here, we report five patients with an established diagnosis of congenital hydronephrosis, who presented with acute abdominal pain and fever and an abrupt increase in the anteroposterior pelvic diameter (APD)...
2022: Case Reports in Nephrology
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