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Current Health Sciences Journal

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https://read.qxmd.com/read/30647956/therapeutic-particularities-with-depot-medications-in-schizophrenia
#1
C Sârbu, G Ș Bădescu, A E Hromei, I D Stănia
Schizophrenia is a neurodegenerative disease with personality degradation, changes in behavior, cognition, affective disorder and reduced socio-professional insertion. Early diagnosis is necessary and maintenance is ensured by antipsychotic treatment and for non-compliant patients there is an alternative to depot medication that greatly improves therapeutic adherence. The study presents the case of a 43-year-old patient diagnosed with paranoid schizophrenia using the Diagnostic and Statistical Manual of Mental Disorders V-TR criteria that showed a favorable evolution under depot treatment...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647955/therapy-side-effects-in-systemic-lupus-erythematosus
#2
R Popa, L A Lautaru, R Lucretiu, D C Ruiu, D Caragea, M Olteanu, A R Mihailovici, C Ene, V Padureanu, R Padureanu, V Cirlig
Glucosteroids (GS) are widely used drugs for various inflammatory pathologies (Nephrotic syndrome, Proliferative glomerulonephritis, Extramembrane glomerulonephritis, Nephropathy of the Nodous Poliarterita (PAN), Nephropathy from purple Henoch-Schonlein, lupus nephropathy (LN), Acute adrenal insufficiency Waterhouse-Friederichsen, Chronic adrenal insufficiency Addison, Systemic Lupus Erythematosus (SLE), Polymyositis and dermatomyositis, Chronic granulomatosis, Crohn's disease, Hemorrhagic rectocolitis, Hemolytic anemias, Acute leukemias and chronic lymphocytic leukemia, Hodgkin's lymphoma)...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647954/a-rare-case-of-upper-calf-swelling-and-necrosis-the-morel-lavall%C3%A3-e-lesion
#3
O Nica, A Grecu, E A Dincă, D Marinescu, M E Ciurea
A 31-year-old patient presented in the Emergency Department with a tibial fracture following a car accident that crushed the lower third of his thigh and the proximal and median part of his calf. Tibial fracture fixation with an intramedullary rod, was complicated by a Morel-Lavallée lesion. Sequential debridement procedures were performed with partially successful granulation tissue proliferation under NPWT (Negative-Pressure Wound Therapy). To further promote the already delaying granulation, plastic surgeons opted for PRP/PRF (Platelet Rich Plasma/Platelet Rich Fibrin) which allowed appropriate skin grafting...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647953/squamous-pulmonary-neoplasia-grafted-on-lesions-of-pulmonary-tuberculosis-sequelae
#4
A Danciu, S Bondari, M Muntean, C Trifan, L Radu, D Bondari
Clinical symptoms of hemoptysis, chest pain, dyspnea, night sweats and weight loss seen in a patient known for 14 years with pulmonary tuberculosis with sequelae lesions, will always guide the diagnose to a reactivated pulmonary tuberculosis. Yet, in this case, the latest pulmonary radiography revealed newly emerging bilateral lesions with the appearance of a macronodular opacity of medium intensity, discreetly non-homogeneous, located apical-sub-clavicular on the right side, but also with an apical-sub-clavicular cavity lesion on the left side, well defined, with uniform opaque content, and clear-cut outline...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647952/3-tesla-magnetic-resonance-imaging-role-in-articular-degenerative-pathology
#5
A I Cotoi, M S Dinu, R E Meetescu, A Bondari, I A Gheonea
Osteoarthrosis is one of the most common degenerative diseases, affecting most of the middle and advanced age population. It is responsible for joint pain, and reduces mobility to functional impotence, thus becoming a public health problem. It is characterized by the destruction of articular cartilage and bone structures forming joints. Although osteoarthritis is considered a disease that occurs predominantly in the elderly, we present herein the case a young female patient, known for pelvic limb inequality and flat leg with advanced arthrosis in the left ankle, secondary to multiple surgical interventions performed at the lower limb...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647951/anaplastic-thyroid-carcinoma-with-gastric-metastasis
#6
A A L Chavez, P Iyer, I M Cazacu, M E Cabanillas, A Rashid, M S Bhutani
INTRODUCTION: Carcinomas of the thyroid gland represent 3% of all malignancies, with 1.3 to 9.8% corresponding to anaplastic thyroid carcinomas (ATC). Metastases are present in 50% of patients when ATC is diagnosed. Gastrointestinal metastases are a rare finding in patients with thyroid carcinoma. CASE REPORT: A 68-year old gentleman with a history of papillary thyroid carcinoma (PTC) underwent surgery and radiopharmaceutical therapy. Restaging studies nine months later suggested wall thickening localizing to the distal stomach...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647950/therapeutic-options-in-pregnant-women-with-thrombophilia-depending-on-the-genetic-mutations-a-prospective-study
#7
J G Nacea, I Rotaru, A M Patrascu, N Cernea
The aim is to evaluate the effects of anticoagulant therapy (Enoxaparine) compared to antiaggregant therapy (Aspirin) on pregnancy outcome depending on the mutational status of clotting factors. The study was conducted prospectively over a 2 years period and included 110 pregnant women, of whom 80 patients diagnosed with hereditary thrombophilia and 30 healthy pregnant women, representing the control group. After careful observation, we concluded a positive influence of Enoxaparine on pregnancy outcome in pregnant women homozygous carriers for factor V Leiden gene mutation and compound heterozygous for Factor V Leiden and Prothrombin G20210A gene mutation...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647949/clinical-and-histopathological-assessment-on-an-animal-model-with-experimental-autoimmune-encephalomyelitis
#8
L E Toader, G C Rosu, B Catalin, V Tudorica, I Pirici, O Taisescu, D F Muresanu
Multiple sclerosis (MS) is a disease of the Central Nervous System (CNS) which alters over 2 million people, and involves an abnormal autoimmune response directed against the brain, nerves and spinal cord. The antigen or the autoimmune target still remains unknown, a fact for which MS is considered to be an immune mediated disease. The pathology involves mainly the white matter, but the gray matter demyelination plays an important role in its pathogenesis. In 80% of the cases with MS, the disease develops relapses...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647948/q-t-interval-prolongation-in-patients-with-liver-cirrhosis
#9
E Țieranu, I Donoiu, O Istrătoaie, A E Găman, L M Țieranu, D I Gheonea, T Ciurea
Liver cirrhosis (LC) is the end stage of chronic liver disease characterized by the appearance of extensive fibrosis and regeneration nodes associated with hepatocyte necrosis in liver but also by the reshuffling of hepatic architecture. The triad consisting of hepatic parenchymal necrosis, regeneration and scarring is always present regardless of the type of clinical manifestation. The Child-Pugh-Turcotte classification dates back more than 30 years and has been widely used in diagnosing and assessing the severity of liver cirrhosis...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647947/prediction-of-post-operative-complication-in-patients-with-valvular-heart-surgery-based-on-o2-challenge-test-and-a-a-gradient
#10
H A Sadeghi, S Sadeghi, B Ghadrdoost
Patients with valvular heart diseases may have more physiological lung derangements and therefore at current study we studied correlation of O2 challenge, A-AG tests and spirometry values of patients who underwent valve surgery on post op respiratory complications. METHOD: 180 adult patients undergoing non-emergency cardiac valvular surgery were studied. On operating room all patients had arterial blood gas profile (ABG) at room air, 20 minutes after putting on ventilator with 100% O2, and pump oxygenator...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647946/a-simple-method-of-calculation-in-excel-for-the-protein-requirements-in-preterm-new-borns
#11
E C Stoicănescu, F Popescu, A Zavate
INTRODUCTION: The nutritional balance between the nutritional requirements of the organism and the intake is a very delicate thing to adjust especially when it comes to the premature new-born in whom often the oral feeding is very challenging and the need for parenteral feeding is very pressing. PURPOSE: The goal of this article is to present a simple method of calculation for the amino acid parenteral intake in preterm infants using the Excel spreadsheet platform as a platform...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647945/clinical-morphological-aspects-in-spinal-tuberculosis
#12
I Procopie, E L Popescu, R M Pleșea, M Dorobanțu, R F Mureșan, C V Lupașcu-Ursulescu, I E Pleșea, D N Anușca
Osteoarticular tuberculosis (OATB) Aim: The authors made a clinical morphological assessment of tissue samples from patients admitted in Surgical Departments of the Emergency County Hospital of Craiova, Romania, between 1990 and 2015, proved as presenting tuberculous lesions of the spine in the Department of Pathology of the same Hospital. MATERIALS AND METHODS: The studied material consisted of bone, joint and sometimes muscle tissue fragments resulted from biopsies or surgical excisions from 7 cases coming out of 54 patients investigated in the above-mentioned period of time, where the established histological diagnosis was tuberculosis (TB)...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647944/histopathological-aspects-of-the-myocardium-in-dilated-cardiomyopathy
#13
R Mitrut, A E Stepan, D Pirici
Dilated cardiomyopathy is the most common form of cardiac muscle disease, accounting for approximately 60% of all cardiomyopathies. We proposed to identify histopathological changes of the myocardium in dilative cardiomyopathy. This study comprised a total of 19 cases, represented by myocardial fragments from deceased patients with diagnosis of dilated cardiomyopathy. Histopathological analysis allowed changes to be observed for both myocytes and myocardial interstitial components. We have found a combination of hypertrophic, atrophic and normal myocardocytes, or associated with the presence of hydropic changes...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647943/treatment-of-lower-limbs-telangiectasias-with-nd-yag-laser-prospective-study-on-446-patients
#14
N G Ianosi, M X Calbureanu-Popescu, L Dragusin, S L Ianosi, C V Tutunaru, C D Neagoe
In the last two decades Nd: YAG laser has become a standard of treatment of telangiectasias of the lower limbs in C1 EAP stage of chronic venous insufficiency. This paper shows the results of a two years study period of telangiectasias of lower limbs with Nd: YAG laser conducted in a specialised centre in this type of procedures. The study group consisted of 446 patients (21 males and 425 females) with telangiectasias (C1 EAP) on the lower limbs between January 2016-December 2017. The patients had to complete a form in which they noted the initial state on a scale from 1 to 10 but also the result of the treatment and the intensity of the pain during the laser treatment...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647942/pancreatic-head-carcinoma-implications-and-correlations-in-a-romanian-population
#15
L M Florescu, I A Gheonea, A M Lăpădat, M M Florescu, A Florescu, T Ciurea
INTRODUCTION: Pancreatic cancers are often an aggressive type of malignancy, with a 5-year survival rate estimated at around 5%. The main purpose of our study was to determine whether or not tumor dimensions influence the presence of jaundice and the diameters of the CBD and Wirsung duct. MATERIAL AND METHODS: The study group included 32 patients (19 males, 13 females) diagnosed with various histological types of pancreatic head cancers who were hospitalized in the Surgery Department of the County Clinical Emergency Hospital of Craiova during 2016-2018...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647941/study-of-histopatological-parameters-of-gastric-carcinomas-with-micropapillary-component
#16
M Dobrițoiu, A E Stepan, C C Vere, I Cataraga, C E Simionescu
Micropapillary carcinoma was recently identified as a carcinoma variant characterized by the presence of small clusters of tumor cells located in optically empty spaces. The study included a number of 14 cases represented by surgical excision specimens diagnosed with gastric carcinoma (tubular, papillary and signet-ring) which associated the micropapillary component in variable proportions. Regarding the low-grade tubular carcinomas, the micropapillary component represented less than 25% of the tumor, while in the high-grade tubular carcinomas and papillary carcinomas it represented 25-50%...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647940/epidemiological-and-histopathological-aspects-of-tongue-squamous-cell-carcinomas-retrospective-study
#17
F I Ion Ciucă Mărăşescu, P C Marasescu, M Matei, A M Florescu, C Margaritescu, S M S Petrescu, C I Dumitrescu
Tongue squamous cell carcinoma is one of the most commonly diagnosed intraoral squamous cell carcinomas (25-40%), being considered an aggressive form of squamous cell carcinoma, as it is most commonly associated with lymph node metastases and the survival rate at five years is below 50%. In according with these data, we have proposed in this study to individualize an epidemiological and histopathological profile of the patients with such oral cancers, diagnosed and treated in the Oral and Maxillofacial Surgery Clinic and in the Otolaryngology Surgery Clinic of the Emergency Clinical County Hospital Craiova, between 2015-2017...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647939/noninvasive-fibrosis-assessment-in-chronic-viral-hepatitis-c-associated-with-end-stage-renal-disease
#18
D C Caragea, B S Ungureanu, D N Florescu, P Popa, M V Sacerdotianu, D I Gheonea, C C Vere
INTRODUCTION: HCV is considered the most encountered viral infection that affect patients after hemodialysis sessions. Even though liver biopsy is considered the golden standard for hepatic diagnosis, additional methods have been used for assessing liver fibrosis. Transient elastography (TE) has evolved as a reference method in some European countries and allows the physician to carry out a fibrosis evaluation in a noninvasive, low-cost and rapid method. Our objective was to assess the efficacy of TE in staging patients with HCV liver disease associated with ESRD, thus choosing the correct moment to perform the procedure...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30647938/histopathological-prognostic-factors-in-clear-cell-renal-cell-carcinoma
#19
B C Andreiana, A E Stepan, C Mărgăritescu, A-M Al Khatib, M M Florescu, R N Ciurea, C E Simionescu
Clear cell renal cell carcinoma (CCRCC) are the most frequent type of renal cell carcinoma. Fuhrman grade and tumor stage are prognostic factors with great importance in survival rate. This study was performed on 75 cases of CCRCC diagnosed by the Anatomical Pathology Laboratory of the County Clinical Emergency Hospital of Craiova between 2014 and 2017. The biological material was represented by pieces of nephrectomy. The cases were analyzed on two criteria: epidemiology (age, sex) and histopathology (Fuhrman grade, tumor stage, architectural pattern, sarcomatoid transformation, and necrosis)...
July 2018: Current Health Sciences Journal
https://read.qxmd.com/read/30746167/investigation-of-achievement-orientation-of-nursing-and-midwifery-students
#20
N Y Filiz, F Erol, H Başaran, F Tanrikulu, Y Dikmen
PURPOSE: This study was conducted to determine the achievement orientation of nursing and midwifery students and to examine some factors that may affect their achievement orientation. MATERIAL/METHODS: The descriptive sample of this research was created by 209 first-year students voluntarily attending and studying in the Department of Nursing and Midwifery at the Faculty of Health Sciences of a public university in Turkey. The data were collected with "Student Presentation Form" and "2x2 Achievement Orientation Scale"...
April 2018: Current Health Sciences Journal
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