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Journals Gastroenterology and Hepatolog...

Gastroenterology and Hepatology From Bed to Bench

https://read.qxmd.com/read/37767320/an-unusual-cause-of-failure-to-thrive
#21
JOURNAL ARTICLE
Saeed Abdi, Naghmeh Salarieh, Pardis Ketabi Moghadam
No abstract text is available yet for this article.
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37767319/a-step-by-step-guide-to-approaching-colon-polyps
#22
JOURNAL ARTICLE
Amir Sadeghi, Naghmeh Salarieh, Pardis Ketabi Moghadam
Colorectal cancer (CRC) is considered one of the most prevalent cancers among Iranian men and women (1). Colorectal polyps, known as precursors of CRCs, are of great importance. Surveillance, locating, and removal of colorectal polyps make them the most modifiable factor apart from other genetic and environmental factors leading to CRCs. Colorectal polyps are defined as outpouchings from superficial and deep layers of mucosa of the colonic wall. They are classified as adenomas, serrated polyps, hyperplastic polyps, and hamartomas based on histological evaluation...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37767318/network-analysis-of-liver-cancer-a-system-biology-approach
#23
JOURNAL ARTICLE
Babak Arjmand, Somayeh Jahani Sherafat, Mostafa Rezaei Tavirani, Maryam Hamzeloo Moghadam, Mohammad Amin Abbasi
AIM: Determining critical dysregulated proteins in liver cancer was the main aim of this study. BACKGROUND: Liver cancer is a common health problem characterized by difficulties in early diagnosis and rapid progression. Due to the lack of targeted drugs and the other features of the disease, the survival rate for patients is extremely low. METHODS: The related dysregulated proteins for liver cancer were retrieved from the STRING database. The queried proteins were included in a network by Cytoscape software, and the central nodes of the network were enriched via gene ontology...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37767317/psychometric-properties-of-persian-version-of-irritable-bowel-syndrome-behavioral-responses-questionnaire-ibs-brq
#24
JOURNAL ARTICLE
Amrollah Ebrahimi, Mohammad Forghani, Masoudeh Bababkhanian, Mehdi Ebrahimi, Peyman Adibi Sedeh
AIM: This study aimed to determine the psychometric properties of Persian version of Irritable Bowel Syndrome-Behavioral Responses Questionnaire (IBS-BRQ). BACKGROUND: In addition to somatic symptoms and complaints, patients with irritable bowel syndrome have specific dysfunctional behaviors that lead to disease persistence and functional disturbance. METHODS: Participants included 170 patients with irritable bowel syndrome, who were diagnosed based on ROM-IV criteria and selected from patients referring to the Gastrointestinal Disorders Clinic, as well as 100 persons from the general population in Isfahan in 2020...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37767316/autologous-platelet-rich-plasma-injection-and-platelet-rich-fibrin-glue-interposition-for-treatment-of-anal-fistula-resistant-to-surgery
#25
JOURNAL ARTICLE
Abbas Abdollahi, Elaheh Emadi, Daryoush Hamidi Alamdari
AIM: The current study purposed to evaluate the autologous platelet-rich plasma (PRP), and platelet-rich fibrin glue (PRFG) effect on the treatment of complex, and recalcitrant anal fistula (AF) which was not cured by several surgeries. BACKGROUND: AF has remained one of difficult challenges for centuries. Surgery is the common treatment method for it, but the risk of fecal incontinence and recurrence is still a distressing complication for patients and surgeons...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37767315/an-unusual-shape-of-ampulla-secondary-to-impaction-of-hydatid-membrane
#26
JOURNAL ARTICLE
Amir Sadeghi, Najmeh Radgoodarzi, Dlnya Aminzade
No abstract text is available yet for this article.
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554759/bone-mineral-density-in-iranian-children-with-celiac-disease
#27
JOURNAL ARTICLE
Shokoufeh Ahmadipour, Mohamad Rostami Nejad, Mojgan Faraji Goodarzi, Siroos Heidarifard, Banafsheh Sedaghat, Khatereh Anbari
AIM: The current study aims to evaluate bone mineral density (BMD) in patients with celiac disease who were referred to the celiac clinic of Shahid Rahimi Hospital in Khorramabad, Iran, in 2020. BACKGROUND: Extraintestinal presentations of celiac disease are widespread and, if neglected, can be devastating. Osteoporosis, one of the extraintestinal manifestations of celiac disease, often remains undiagnosed until advanced stages and can impose a significant burden on patients with celiac and health systems...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554758/the-correct-methodological-approach-to-the-diagnosis-of-celiac-disease-the-point-of-view-of-the-pathologist
#28
REVIEW
Vincenzo Villanacci, Rachele Del Sordo, Giovanni Casella, Gabriel Becheanu, Arianna Oberti, Baraa Belfekih, Gabrio Bassotti, Alberto Ravelli
The diagnosis of celiac disease relies on the assessment of serological data and the presence of histological alterations in the duodenal mucosa. The duodenal biopsy is pivotal in adults, and in some circumstances in children, to confirm the clinical suspicion of celiac disease. The correct interpretation of duodenal biopsies is influenced by numerous variables. The aim of this overview is to describe the correct methodological approach including the procedures of biopsy sampling, orientation, processing, staining and histopathological classification in order to avoid or minimize the errors and the variability in duodenal biopsy interpretation...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554757/long-term-follow-up-in-patients-with-coeliac-disease-in-the-pandemic-era-a-view-from-sheffield-the-nhs-england-national-centre-for-adult-coeliac-disease
#29
JOURNAL ARTICLE
Nick Trott, Suneil A Raju, Anupam Rej, Olivia Hoffman, William Holland, James R Bebb, Leah Seamark, Marianne Williams, Cristian Costas Batlle, Yvonne M Jeanes, Luca Elli, David S Sanders
AIM: To explore patients' follow-up preferences. BACKGROUND: Optimal follow-up strategies for patients with coeliac disease remain a subject of debate. Research suggests patients' prefer review by dietitians with a doctor available as required. METHODS: Patients with coeliac disease under review at our centre, completed a questionnaire assessing their views on what makes follow-up useful based on specific criteria. Bloods tests, symptoms review, dietary assessment, opportunity to ask questions and reassurance...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554756/the-role-of-serology-in-the-diagnosis-of-coeliac-disease
#30
REVIEW
Umberto Volta, Julio Cesar Bai, Roberto De Giorgio
Serology has significantly revolutionized the knowledge of celiac disease (CD), leading to the identification of unsuspected patients in at-risk CD groups, thereby increasing the number of CD diagnoses compared to the pre-screening era. Several markers for CD with a progressive diagnostic accuracy have been identified over the years, but only three of them, i.e. anti-tissue transglutaminase (anti-tTG), anti-endomysial (EmA) and anti-deamidated gliadin antibodies (DGP) are currently assessed in the daily clinical practice...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554755/assessment-of-iron-status-and-iron-deficiency-anemia-in-patients-with-celiac-a-single-center-experience
#31
JOURNAL ARTICLE
Seyyed Ali Pirzadeh, Taghi Amiriani, Sima Besharat, Alireza Norouzi, Haniyeh Mirkarimi, Nesa Shokouhifar, Gholamreza Roshandel, Amrollah Sharifi
AIM: This study aimed to assess the status of iron stores and the frequency of iron deficiency anemia in Celiac disease (CD) patients referred to the Golestan Research Center of Gastroenterology and Hepatology, Gorgan, Iran. BACKGROUND: Studies have shown that nutritional deficiencies affect 20-38% of patients with CD due to malabsorption and as a result of a gluten-free diet. METHODS: In this study, 59 out of 100 CD patients were assessed...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554754/no-biopsy-diagnostic-approach-to-coeliac-disease
#32
REVIEW
Geoffrey Holmes
This brief review outlines contributions that Michael Marsh and others made to understanding the structure and function of the upper small bowel mucosa and the formation of abnormalities that occur in coeliac disease (CD). He introduced his classification of lesions 30 years ago that has been widely adopted. The development and use of serological tests to screen for and diagnose CD in children and adults without the need for a small bowel biopsy in a considerable proportion is also recognised and will gain traction...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554753/transient-non-coeliac-gluten-sensitivity-ncgs-with-markedly-reduced-villous-height-crypt-depth-ratio
#33
Charlotte Williams, Nicole Smith, Kamran Rostami
There is no confident evidence in the current literature to show or demonstrate that non-coeliac gluten sensitivity (NCGS) exclusively presents with mild or nearly normal duodenal mucosal abnormality. Gluten sensitive patients with negative serology and severe mucosal changes are labelled with the term seronegative coeliac disease (SNCS). There might be at least some overlap between NCGS and SNCD. Transient gluten sensitivity with severe mucosal changes without CD have been previously reported like in our case...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554752/deep-dive-directions-for-dietitians-dddds-a-roadmap-for-the-nutritional-management-of-poorly-responsive-coeliac-disease-patients
#34
REVIEW
Adele Rostami, Sabine Hogg-Kollars
A substantial number of coeliac disease patients fail to respond to treatment with a gluten-free diet. Non-responsiveness might be multifactorial and the spectrum ranges from intentional or inadvertent gluten contamination as the main aetiology, to sensitivity to other nutrients (in addition to additives and preservatives). If the diagnosis of coeliac disease is correctly made and cross contamination and other factors have been excluded, then the aetiology behind the symptoms of a small group of coeliac patients might be refractory coeliac disease...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554751/not-all-enteropathies-are-coeliac-disease-report-of-an-infant-with-microvillus-inclusion-disease
#35
Eda Nur Kozan, Ceyda Tuna Kırsaçlıoğlu, Zarife Kuloğlu, Aydan Kansu, Berna Savas, Arzu Ensari
Primary enteropathies of infancy comprise of epithelial defects including microvillus inclusion disease, tufting enteropathy, and enteroendocrine cell dysgenesis and autoimmune enteropathies. The diseases in this group cause severe chronic (>2-3 weeks) diarrhoea starting in the first weeks of life and resulting in failure to thrive in the infant. Duodenal biopsies show moderate villous shortening together with crypt hyperplasia which are the main features causing resemblance to coeliac disease. We, hereby, report a term-born male infant of consanguineous parents...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554750/clinical-profile-of-patients-with-seronegative-celiac-disease
#36
JOURNAL ARTICLE
Elham Rahmanipour, Mohammad Ghorbani, Azita Ganji, Zahra Mirzaei, Vahid Ghavami, Bijan Shahbazkhani, Fahime Attarian, Masoumeh Amiri
AIM: This study aimed to determine the clinical profile of patients with seronegative celiac disease (SNCD). BACKGROUND: Celiac disease (CD) is mainly diagnosed based on positive serology and duodenal mucosal atrophy, but some patients have negative serology. Their diagnosis has some limitations; delays in diagnosis are likely accompanied by a poor prognosis and a high risk of developing complications of CD. METHODS: In this retrospective study, 1115 patients were evaluated for CD with mucosal atrophy between 2010 to 2020...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554749/tufting-enteropathy-a-rare-anatomical-cause-of-small-bowel-diarrhoea-in-infants-with-mild-or-no-villous-abnormality
#37
Prasenjit Das, Rohan Malik, Sanjeevani Kaul, Govind K Makharia
The causes of intractable diarrhoea in infancy are varied, and can be classified into enteropathic and non-enteropathic groups. Congenital tufting enteropathy (CTE) is a rare cause of enteropathic form of intractable diarrhoea in infants requiring nutritional supplementation. We herein report a case of CTE in a one-year-old female child who presented with recurrent abdominal distension, frequent watery diarrhoea and marked stunted growth soon after birth. A systematic clinical, laboratory and pathological evaluation brought out the etiology, followed by genotypic confirmation...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554748/celiac-disease-experience-of-general-practitioners-in-brianza-area-monza-milan-italy
#38
JOURNAL ARTICLE
Giovanni Casella, Maria Teresa Bardella, Fabio Ingravalle, Adriana Ingravalle, Stefano Andreotti, Aurelio Limonta, Claudio Monti, Vincenzo Villanacci, Gabrio Bassottia
AIM: The purpose of the study was to better investigate the degree of knowledge and the diagnostic approach concerning celiac disease and its extra-intestinal manifestations by general practitioners in Italy. BACKGROUND: Celiac Disease is a common chronic disease, but often goes undiagnosed because of atypical symptoms or silent disease. Currently there are non-definitive data about the disease management approach concerning celiac disease by general practitioners...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554747/predictors-of-slow-responsiveness-and-partial-mucosal-recovery-in-adult-patients-with-celiac-disease
#39
JOURNAL ARTICLE
Roxana Nemteanu, Mihai Danciu, Andreea Clim, Irina Girleanu, Irina Ciortescu, Liliana Gheorghe, Anca Trifan, Alina Plesa
AIM: The present study aims to determine the rate of mucosal recovery and predictors of persistent mucosal damage after gluten free diet (GFD). BACKGROUND: Celiac disease (CD) is a complex multi-systemic autoimmune disease triggered by exposure to dietary gluten in genetically predisposed individuals. There is still little evidence on the best method for assessing GFD adherence and mucosal recovery during treatment. METHODS: The retrospective study included only adult patients (age≥18 years old), with biopsy-proven CD evaluated at a tertiary referral centre between 2016 and 2021...
2023: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/37554746/the-differential-diagnoses-for-severe-enteropathy-or-severely-damaged-small-intestinal-mucosa
#40
JOURNAL ARTICLE
Chao Ling Aran Jian, David T S Hayman, Bruce Lockett, Kamran Rostami
AIM: The aim of this study was to explore the aetiology of severe duodenal mucosal abnormality in consecutive patients who underwent gastroscopy and duodenal biopsy over the past 10 years. BACKGROUND: A range of differential diagnoses have been reported for severe duodenal architectural distortion. METHODS: Clinical and laboratory data of all the patients with severe duodenal architectural distortion diagnosed at MidCentral District Health Board (DHB), New Zealand were collected and statistically analysed...
2023: Gastroenterology and Hepatology From Bed to Bench
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