Mohammad Reza Mirinezhad, Maliheh Aghsizadeh, Mohammadreza Fazl Mashhadi, Sara Moazedi, Maryam Mohammadi Bajgiran, Hamideh Ghazizadeh, Shayan Yaghouti, Mahdi Mohammadian Ghosooni, Mohammad Amin Mohammadi, Elahe Hasanzadeh, Ali Ebrahimi Dabagh, Arezoo Rastegarmoghadam Ebrahimian, Ensieh Akbarpour, Habibollah Esmaily, Gordon A Ferns, Tayebeh Hamzehloei, Alireza Pasdar, Majid Ghayour-Mobarhan
BACKGROUND: Premature menopause (PM) is the cessation of ovarian function before age 40. PM women are more likely to have cardiovascular diseases (CVDs), diabetes, and mental disorders. This is the first study that assessed the association of single nucleotide polymorphisms (SNPs) with anti-heat shock protein 27 (Hsp27), High-sensitivity C-reactive protein (hs- CRP), and PM and serum pro-oxidant-antioxidant balance (PAB), as putative risk factors for CVDs. We aimed to explore the association of oxidative stress markers with eight different SNPs shown to be related to premature menopause...
February 2, 2024: International Journal of Fertility & Sterility