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International Journal of Fertility & Sterility

Fatemeh Hadi, Elham Shirazi, Shiva Soraya
No abstract text is available yet for this article.
April 2019: International Journal of Fertility & Sterility
Isabel Lobo Antunes, Cláudia Tomás, Íris Bravo, José Luís Metello, Ana Quintas, Pedro Sá E Melo
Müllerian anomalies are very common, and a frequent cause of infertility. The most used classification system until now, proposed by the American Society for Reproductive Medicine in 1988, categorizes comprehensively uterine anomalies but fails to classify defects of the cervix or vagina. This is based on a developmental theory that postulates that müllerian duct fusion is unidirectional, beginning caudally and extending cranially, which does not account for isolated cervical or vaginal defects. More recently, the European Society of Human Reproduction and Embryology has developed a consensus, which allows for independent cervical anomalies...
April 2019: International Journal of Fertility & Sterility
Fatemeh Dehghanpour, Farzaneh Fesahat, Seyed Mohsen Miresmaeili, Ehsan Zare Mehrjardi, Ahmad Honarju, Ali Reza Talebi
Single nucleotide polymorphisms (SNPs) in a number of genes involved in sperm maturation are considered as one of the main factors for male infertility. The aim of the present case-control study was to examine the association of SNPs in protamine1 (PRM1) and protamine2 (PRM2) genes with idiopathic teratozoospermia. In this case-control study, some SNPs in PRM1 (c.49 C>T, c.102 G>T and c.230A>C) and PRM2 (rs545828790, rs115686767, rs201933708, rs2070923 and rs1646022) were investigated in 30 idiopathic infertile men with teratozoospermia (case group) in comparison with 35 fertile men (controls)...
April 2019: International Journal of Fertility & Sterility
Azza Ibrahim Abd El-Kader, Amina Saad Gonied, Mohamed Lotfy Mohamed, Sabah Lotfy Mohamed
Background: Endometriosis is considered the most common cause of pelvic adhesions in women. Endometriosisassociated adhesions could result in the formation of fibrous bands, which contain endometriotic glands, stroma and scarring. The aim of this study was to identify the impact of endometriosis-related adhesions on quality of life among infertile women. Materials and Methods: This descriptive study was conducted at Endoscopic Unit, in Zagazig University Hospitals, Egypt...
April 2019: International Journal of Fertility & Sterility
Saman Maroufizadeh, Mostafa Hosseini, Abbas Rahimi Foroushani, Reza Omani-Samani, Payam Amini
Background: Infertility, one of life's great stressors, may adversely affect marital satisfaction. No studies have investigated the relationship between perceived stress and marital satisfaction at the dyadic level. The current study assessed the actor and partner effects of perceived stress on marital satisfaction in husband-wife dyads using an innovative dyadic analysis approach, the Actor-Partner Interdependence Model (APIM). Materials and Methods: In this cross-sectional study, we recruited a total of 141 infertile couples...
April 2019: International Journal of Fertility & Sterility
Sepideh Ganjalikhan Hakemi, Fariba Sharififar, Tahereh Haghpanah, Abdolreza Babaee, Seyed Hassan Eftekhar-Vaghefi
Background: Busulfan (BU) has a destructive effect on the male reproductive system. The goal of this study was to assess the effects of olive leaf extract (OLE) as a source of antioxidants and phenolic compounds, on BU-induced damages in rat testes. Materials and Methods: In this experimental study, 40 male Wistar rats were randomly divided into 5 groups. The control group (CTL) received a single intraperitoneal (i.p.) injection of dimethyl sulfoxide (DMSO), followed by oral administration of distilled water for 5 weeks...
April 2019: International Journal of Fertility & Sterility
Rasoul Kheradmandi, Seyed Gholam Ali Jorsaraei, Farideh Feizi, Ali Akbar Moghadamnia, Nahid Neamati
Background: Chlorpyrifos (CPF), an organophosphate pesticide, is widely used in farms in order to preserve crops and fruits. Previous studies have shown that CPF exposure might cause chronic toxicity in male genital system. The present study investigated the protective effect of N-Acetyl Cysteine (NAC), a potent antioxidant against testicular toxicity of CPF in male mice. Materials and Methods: In this experimental study, 42 adult male mice were divided into seven groups, CPF low (0...
April 2019: International Journal of Fertility & Sterility
Bahia Namavar Jahromi, Farnaz Farrokhnia, Nader Tanideh, Perikala Vijayananda Kumar, Mohammad Ebrahim Parsanezhad, Sanaz Alaee
Background: The purpose of this study was to compare the effects of Glycyrrhiza glabra (Licorice), a cyclooxygenase- 2 inhibitor (Celecoxib) and a gonadotropin-releasing hormone analog (Diphereline®), with a control group on endometrial implants in rats. Materials and Methods: In this experimental study, endometriosis was induced in rats by auto transplantation and after confirmation, the rats were divided into 4 groups that were treated for 6 weeks with normal saline (0...
April 2019: International Journal of Fertility & Sterility
Sanne C Braam, Dimitri Consten, Jesper M J Smeenk, Ben J Cohlen, Max H J M Curfs, Carl J C M Hamilton, Sjoerd Repping, Ben W J Mol, Jan Peter de Bruin
Background: In vitro maturation (IVM) is an artificial reproductive technology in which immature oocytes are harvested from the ovaries and subsequently will be matured in vitro. IVM does not require ovarian hyperstimulation (OH) and thus the risk of ovarian hyperstimulation syndrome (OHSS) is avoided. In this study, we assessed the live birth rate per initiated IVM cycle in women eligible for in vitro fertilization/intracytoplasmic sperm injection (IVF/ ICSI) and at risk for OHSS. Furthermore, we followed women who were not pregnant after IVM and committed to a conventional IVF/ICSI procedure...
April 2019: International Journal of Fertility & Sterility
Azam Kouhkan, Mohammad E Khamseh, Ashraf Moini, Reihaneh Pirjani, Arezoo Arabipoor, Zahra Zolfaghari, Roya Hosseini, Hamid Reza Baradaran
Background: The aim of the present study was to determine the maternal pre-pregnancy body mass index (BMI), first-trimester fasting blood sugar (FBS), and the combination of (BMI+FBS) cut-points for at-risk pregnant women conceived by assisted reproductive technology (ART) to better predict the risk of developing gestational diabetes mellitus (GDM) in infertile women. Materials and Methods: In this nested case-control study, 270 singleton pregnant women consisted of 135 (GDM) and 135 (non-GDM) who conceived using ART were assessed...
April 2019: International Journal of Fertility & Sterility
Arezoo Arabipoor, Mahnaz Ashrafi, Mandana Hemat, Zahra Zolfaghari
Background: We designed the present study to evaluate the simultaneous effect of obesity in couples on in vitro fertilization/ intracytoplasmic sperm injection (IVF/ICSI) outcomes. Materials and Methods: In this cross-sectional study, performed at Royan Institute between January 2013 and January 2014, we evaluated the recorded data of all patients during this time period. The study population was limited to couples who underwent ICSI or IVF/ICSI cycles with autologous oocytes and fresh embryo transfers...
April 2019: International Journal of Fertility & Sterility
Sara Abedi, Mahboubeh Taebi, Mohammad Hosein Nasr Esfahani
Background: Despite numerous studies indicating an imperative role for reproduction, however, the role of Vitamin D supplementation on outcomes of assisted reproductive techniques remains controversial. This clinical trial was performed to evaluate the effect of Vitamin D supplementation 6 weeks prior to intracytoplasmic sperm injection (ICSI) on fertility indices. Materials and Methods: The present study was a double-blind clinical trial conducted on infertile women was randomly allocated into two groups: Vitamin D supplementation (42 participants) and placebo (43 participants)...
April 2019: International Journal of Fertility & Sterility
Azam Azargoon, Yasaman Mirrasouli, Mahdieh Shokrollahi Barough, Mehdi Barati, Parviz Kokhaei
Background: The prognostic value of peripheral natural killer (pNK) cells, as a screening test in women with recurrent pregnancy loss (RPL) and unexplained infertility, is still a matter for discussion. The purpose of this study was to compare the percentage of circulating CD56+ NK cells, CD69 and perforin markers between women with unexplained infertility and RPL with the healthy control group. Materials and Methods: In this case-control study, the percentage of CD56+ NK cells and activation markers (CD69 and perforin levels) in the peripheral blood were measured in 25 women with unexplained infertility, 24 women with idiopathic RPL and 26 women from the healthy control group, using specific monoclonal antibodies by flow cytometry...
April 2019: International Journal of Fertility & Sterility
Babak Babaabasi, Ali Ahani, Faegheh Sadeghi, Haniyeh Bashizade-Fakhar, Hamid Reza Khorram Khorshid
Background: Tumor necrosis factor-alpha (TNF-α) is an important cytokine in acute inflammatory response to infective factors. Based on investigation in different populations, it is thought that this response increases in patients with endometriosis due to the presence of cytokines such as TNF-α. This study aimed to examine the association of four TNF-α polymorphisms, namely -238G/A, -308G/A, -857C/T and -863C/A, with susceptibility to endometriosis in an Iranian population. Materials and Methods: We recruited 150 women with endometriosis and 150 women without endometriosis in this case-control study and collected 4 ml of blood from all subjects...
April 2019: International Journal of Fertility & Sterility
Vasilios Pergialiotis, Nikoletta Maria Tagkou, Athina Tsimpiktsioglou, Olga Klavdianou, Antonia Neonaki, Pantelis Trompoukis
Urocortin (UCN) is a neuropeptide that belongs to the corticotrophin-releasing hormone family and is expressed by eutopic and ectopic human endometria. The past years, this expression has been thoroughly investigated in the field of endometriosis. The objective of this systematic review is to accumulate current evidence related to the expression of UCN in tissue and blood samples of patients suffering from endometriosis. Literature search was designed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and primarily conducted using the Medline (1966-2018), Scopus (2004-2018), EMBASE (1947-2018) and Clinicaltrials...
April 2019: International Journal of Fertility & Sterility
Evangelos G Papanikolaou, Evi Timotheou, Petroula Tatsi, Hieronymus Janssens, Michael Grynberg, Apostolos Athanasiadis, Christina Zafeirati, Robert Najdecki, Stamatios Petousis
The efficacy of in vitro fertilization (IVF) for treating human infertility has only one final efficacy index and that is the achievement of a delivery. However, with the evolution of the freeze-all strategy, a new problem is arising for evaluating the performance of an embryological team. The aim of the study was to present a new representative index, combining fresh and frozen embryo transfer success rates. In this opinion article, apart from the effectiveness of managing fresh gametes and embryos, we wish to evaluate the efficacy of the processes of both freezing and thawing of the produced embryos...
January 2019: International Journal of Fertility & Sterility
Matías Angel Sirini, Juan Patricio Anchordoquy, Silvina Quintana, Cecilia Furnus, Alejandro Enrique Relling, Juan Mateo Anchordoquy
Energy balance is regulated by ghrelin which is a neuroendocrine modulator. Ghrelin is expressed in reproductive organs. However, the role of ghrelin during in vitro maturation (IVM) and bovine preimplantational development is limited. The purpose of this study was to measure the expression of ghrelin (GHRL) and its receptor growth hormone secretagogue receptor 1A (GHS-R1A) mRNA, and determine cumulus oocyte complex (COC) viability after IVM with 0, 20, 40 and 60 pM of ghrelin. Also, pronuclear formation was recorded after in vitro fertilization (IVF)...
January 2019: International Journal of Fertility & Sterility
Mahboobeh Shirazi, Parichehr Pooransari, Fatemeh Rahimi Sharbaf, S Hirin Niromanesh, Behrokh Sahebdel, Mamak Shariat, Zeinab Pahlavan, Mahmoud Shirazi, Maryam Ahmadian
Background: Antenatal anxiety or maternal stress is a prevalent chronic mental disorder in pregnant women. We have assessed the effect of maternal stress from positive aneuploidy screening results on the changes in uterine artery blood flow. Materials and Methods: We performed a prospective cohort (one sample) pilot study at a hospital in Tehran, Iran. A total of 60 pregnant women who were candidates for amniocentesis due to abnormal sequential screening test results entered the study...
January 2019: International Journal of Fertility & Sterility
Zahra Ezabadi, Fahimeh Mollaahmadi, Saeideh Sazvar, Samira Vesali, Reza Omani-Samani
Background: Potentially modifiable factors, such as the appropriate informing process given to infertile patients, can affect their infertility knowledge and information. This study aims to assess infertility information provided to Iranians who undergo assisted reproductive treatment. Materials and Methods: In this cross-sectional study, participants recruited were a convenience sample of all infertile patients who received assisted reproductive treatments from Royan Institute, Tehran, Iran...
January 2019: International Journal of Fertility & Sterility
Maryam Jahangirifar, Mahboubeh Taebi, Mohammad Hossein Nasr-Esfahani, G Holamreza Askari
Background: Infertility is one of the most common challenges that women in reproductive age would encounter today. The maternal nutritional status could be a determinant of oocyte quality and embryonic growth. This study was conducted to assess the relationship between dietary patterns and reproductive outcomes in infertile women. Materials and Methods: This prospective cohort study was conducted on 140 women with primary infertility who had referred to Isfahan Fertility and Infertility center, Isfahan, Iran...
January 2019: International Journal of Fertility & Sterility
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