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Iranian Journal of Child Neurology

Zahra Bagherian, Omid Yaghini, Hossein Saneian, Shervin Badihian
Objectives: Cyclic vomiting syndrome (CVS) is a chronic functional gastrointestinal disorder with no certain treatment. We aimed to compare the efficacy of amitriptyline and topiramate on prophylactic therapy of CVS. Materials & Methods: This randomized clinical trial (registration number: IRCT2015102316844N2) was conducted during 2016 in Isfahan, central Iran. The inclusion criteria were CVS patients (based on Rome III) aging 3-15 yr with normal physical examination, no metabolic disorder, and no gastrointestinal obstruction or renal impairment...
2019: Iranian Journal of Child Neurology
Khodayar Oshvandi, Marzieh Jahani Sayad Noveyri, Salam Vatadost
No abstract text is available yet for this article.
2019: Iranian Journal of Child Neurology
Virender Kumar Gehlawat, Jaya Shankar Kaushik, Poonam Mehta, Geeta Gathwala, Rachana Dubey
Varicella infection in children is a common self-limited illness with neurological complications in less than 0.1% of cases. Longitudinally extensive transverse myelitis (LETM) is uncommon in children following infection with varicella-zoster virus. We describe a case of 13-yr immunocompetent girl with LETM following varicella infection shown a dramatic clinical response to a combination of acyclovir and pulse steroids.
2019: Iranian Journal of Child Neurology
Edin Begic, Haris Bradaric, Zijo Begic, Amra Dobraca
Lafora progressive myoclonus epilepsy (Lafora disease, LD) is a fatal autosomal recessive neurodegenerative disorder (with an onset in teenage years in previously normal adolescents). This paper represents a view of a patient diagnosed with Lafora progressive myoclonus epilepsy, over a course of seven years. A description of the initial manifestation of symptoms, doctors' attempts to combat the symptoms with drug treatment, further attempts towards reaching the correct diagnosis, the final confirmation of the Lafora diagnosis (mutation in the NHLRC1 gene), and the current state of the patient is presented...
2019: Iranian Journal of Child Neurology
Mohammad Vafaeeshahi, Nazanin Azizishalbaf, Leila Tahernia
Cerebellar acute ischemic stroke (AIS) can be a complication of minor head trauma, vertebral artery dissection, vasospasm or systemic hypoperfusion. CT scan usually is negative few hours after acute infarction. Magnetic resonance imaging (MRI) is superior to CT scan for posterior fossa lesions and also in acute phase of cerebellar stroke especially in children. Here we report a 9 yr old girl referred to the Pediatric Emergency Room, Moosavi Hospital, Zanjan, Iran in January 2017 presenting with sudden onset of headache and recurrent vomiting, ataxia, and history of 3 consecutive days of fever and malaise...
2019: Iranian Journal of Child Neurology
Mohsen Abbasi Kangevari, Ali Asghar Kolahi, Ahmad Reza Farsar, Saeid Kermaniranjbar
Objectives: People with epilepsy generally encounter misconceptions and negative attitudes on different aspects of the disease. They are also prone to physical injuries during seizures. Lack of awareness about first-aid measures results in taking inappropriate first-aid measures. We aimed to determine the public awareness, attitudes, and first-aid measures about epilepsy in Tehran. Materials & Methods: This population-based cross-sectional survey was conducted from Dec 2016 to May 2017 in Tehran, Iran...
2019: Iranian Journal of Child Neurology
Jamileh Fattahi, Ali Akbar Tahaei, Hassan Ashayeri, Ghassem Mohammadkhani, Shohreh Jalaie
Objectives: Sometimes there is no hearing impairment, but it is possible to have an auditory disorder. This is known as a central auditory processing disorder (CAPD). Speech dichotic tasks are useful tools to evaluate CAPD, but there is almost no tool to assess this for Azeri people in their native language. The aim of this study was to evaluate central auditory processing of Azeri participants by Azeri dichotic digit test (ADDT). Materials & Methods: Participants were 52 normal Iranian Azeri students (mean age 23...
2019: Iranian Journal of Child Neurology
Mamak Shariat, Parisa Mohagheghi, Zahra Farahani, Nasrin Khalesi, Maryam Nakhostin
Objectives: We aimed to compare the level of significance of risk factors related Intraventricular hemorrhage (IVH) between preterm infants born after IVF and non-IVF conceptions. Materials & Methods: This historical cohort study was done in four Iranian Hospitals in 2013-2014. Overall, 155 preterm newborns were divided into case (IVF) and control (normal conception) groups. Both groups' demographic data were extracted and recorded. The incidence of IVH and its grades were compared between case and control groups...
2019: Iranian Journal of Child Neurology
Zarin Taj Keihani Doust, Fatemeh Noori Sari, Parvin Akbari Asbagh, Zahra Farahani, Fatemeh Tehrani, Mamak Shariat
Objectives: Stroke is a sudden blockage or rupture of brain vessels resulting neural defect or impairment. We aimed to investigate the incidence and causes of stroke in hospitalized children (Tehran-Iran, 2008-2013). Materials & Methods: This case series study was carried out in pediatric ward of tertiary care Vali-Asr Hospital, Imam Khomeini Hospitals Complex (Tehran- Iran) from 2008 to 2013. One month to 15 yr old admitted children due to stroke were enrolled into this case series study...
2019: Iranian Journal of Child Neurology
Reza Sharafi, Afagh Hassanzadeh Rad, Vahid Aminzadeh
Objective: We aimed to investigate the risk factors of febrile status epilepticus (FSE) in children. Materials & Methods: This analytic case-control study was conducted on all patients' records with first febrile seizure (FS) admitted to 17 Shahrivar Hospital, Rasht, Iran during 2007-2014. Cases were children aged 6 to 60 months with FSE and controls were children with complex and simple FS. Data were gathered using a checklist including age, sex, type of milk consuming during first year, temperature, the interval between fever and seizure, family history of epilepsy and febrile seizure, and prematurity...
2019: Iranian Journal of Child Neurology
Soheila Nouraie, Sedigheh AMIRALIl Akbari, Roshanak Vameghi, Alireza Akbarzade Baghban
Objectives: Delayed umbilical cord clamping (DCC) increases blood transfer to newborns. Hence we investigated the effect of the timing of DCC on hemoglobin levels, neonatal outcomes and developmental status in infants at four months old. Materials & Methods: This clinical trial examined infants born to 400 pregnant women immediately upon birth and at the age of four months in Isfahan, central Iran in 2016. A table of random numbers was used to randomly allocate the newborns to intervention group with a 90-120-sec delay in umbilical cord clamping and the control group with a clamping delay of below 60 sec, and blood samples were taken from their umbilical cords...
2019: Iranian Journal of Child Neurology
Somaye Kavousipor, Mehdi Rassafiani, Abbas Ebadi, Farin Solimani, Ali Hosseini, Carl Gabbard
Objectives: This study aimed to translate the Affordance in the Home Environment for Motor Development (AHEMD) scales (3-18 months (IS) and 18-42 month (SR) versions) into Persian and examine its cultural adaptation and psychometric properties. Materials & Methods: Four stages process was conducted as translation of the questionnaires (use of International Quality of Life Assessment protocol), cultural adaptation, and determination of its psychometric properties...
2019: Iranian Journal of Child Neurology
Mohammad Reza Alaei, Aydin Tabrizi, Narjes Jafari, Hadi Mozafari
Gaucher disease (GD) is a rare inherited metabolic disorder and the most common lysosomal storage disorder, caused by a deficiency in glucocerebrosidase enzyme activity. It has been classified according to the neurological manifestations into three types: type 1, without neuropathic findings, type 2 with acute infantile neuropathic signs and type 3 or chronic neuropathic form. However, report of new variants has led to the expansion of phenotype as a clinical phenotype of GD considered as a continuum of phenotypes...
2019: Iranian Journal of Child Neurology
Sedigheh Rafiei Tabatabei, Roxana Azma, Manijeh Kahbazi, Abdonaser Farzan, Maryam Kazemi Aghdam, Kimia Seifi, Negin Nahanmoghaddam
Gram-negative meningitis can occurssubsequent to dura-arachnoid barrier disruption because of trauma, surgery and rarely an infected dermoid cyst. Association of neurosurgical procedures with Gram-negative meningitis was described for the first time in 1940. Intracranial infections from gram-negative bacilli like Enterobacter are serious and difficult to treat as many antibiotics fail to achieve bactericidal concentrations in the cerebrospinal fluid. Here in, we report a rare case of pediatric Enterobacter meningitis in a patient with a dermoid cyst that had been manipulated...
2018: Iranian Journal of Child Neurology
Amiereza Vafaee, Taghi Baghdadi, Sara Norouzzadeh
A 7-yr-old patient was referred to pediatric orthopedic clinic of Imam hospital (2016) with the diagnosis of cerebral palsy (CP). His parents were concerned about some inconsistency of his disease progression. After initial evaluations, the diagnosis of CP was incorrect. The true diagnosis was suspected and confirmed with molecular genetic analysis. A rare autosomal recessive disorder -Cockayne syndrome- was diagnosed. Although untreatable, it can be prevented by appropriate prenatal diagnostic tests for their future children...
2018: Iranian Journal of Child Neurology
Zarrin Keihanidost, Aydin Tabrizi, Elahe Amini, Mojtaba Sedaghat, AmirAli Ghahremani, Mamak Shariat, Zeinab Kavyani
Objectives: Hearing loss is one of the most important disabilities in neonates. Delay in the detection of hearing loss leads to impaired development and may prevent the acquisition of speech. We aimed to determine the risk factors associated with hearing loss in neonatal patients aged more than 6 months with a history of hospitalization in Neonatal Intensive Care Unit (NICU). Methods: In this case-control study, screening for hearing loss was carried out on 325 neonates aged 6-12 months referred to Pediatric Neurology Office of Vali-e-Asr Hospital, Tehran, Iran up to 2011...
2018: Iranian Journal of Child Neurology
Sousan Salehi, Ahmad Reza Khatoonabadi, Mahmoud Reza Ashrafi, Ghasem Mohammadkhani, Saman Maroufizadeh, Fatemeh Majdinasab
Objectives: Emotion is a key component in language processing, but emotional words processing in children is still controversial. We aimed to investigate the relationship between emotional dimensions, arousal and valence, word familiarity, comprehension, use, and emotional content recognition. Eventually, a list of emotional content words for this age was prepared in Persian. Materials&Methods: The study was conducted in selected elementary schools in Tehran, Iran from April to June 2017...
2018: Iranian Journal of Child Neurology
Zahra Babaei, Talieh Zarifian, Atieh Ashtari, Enayatollah Bakhshi, Mona Ebrahimpour
Objectives: Human beings can use gestures such as pointing and reaching to communicate with others before they have the ability to use verbal communication to produce speech. Given the importance of children's communication development and the key role of gestures development in communicating, the main purpose of this study was to analyze the normal development of pointing and reaching gestures and their relationship in 12-16-month-old children speaking Farsi. Materials & Methods: In this prospective, observational and longitudinal study the gestures of 11 monolingual Farsi-speaking children (7 boys and 4 girls, from Oct 2015 to Jan 2017 in the homes of participants across Tehran, Iran) were evaluated via non-randomized sampling method...
2018: Iranian Journal of Child Neurology
Abolfazl Mahyar, Parviz Ayazi, Elaheh Azimi, Reza Dalirani, Ameneh Barikani, Shiva Esmaeily
Objectives: Febrile seizure is the most common type of seizure among children. Identification of factors involved in febrile seizure is highly critical. The present study was conducted to determine the association between children's urinary tract infection and febrile seizure. Materials & Methods: In this case-control study, 165 children with simple febrile seizure (case group) were compared with 165 children with fever and without seizure (control group) in terms of urinary tract infection (UTI) in Qazvin, central Iran in 2015-2016...
2018: Iranian Journal of Child Neurology
Kolsoum Saeidi, Nasrollah Saleh Gohari, Seyed Ebrahim Mansouri Nejad
Objectives: Ataxia telangiectasia (AT) is a rare autosomal recessive disorder caused by mutation in the Ataxia telangiectasia mutated (ATM) gene. This disorder is characterized by progressive cerebellar ataxia, telangiectasia, immunodeficiency and a predisposition to leukemia/lymphoma. In this study, we investigated a family with a new mutation in ATM, confirmed by molecular genetic test. Materials&Methods: Four members of a family including a symptomatic AT patient, his parents and sibling were examined for ATM gene defects at Kerman University Hospital, Kerman, Iran in 2016...
2018: Iranian Journal of Child Neurology
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