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Iranian Journal of Reproductive Medicine

Marzieh Talebian, Fatemeh Rahimi-Sharbaf, Mahboobeh Shirazi, Batool Teimoori, Narges Izadi-Mood, Soheila Sarmadi
BACKGROUND: Monozygotic monochorionic triplet pregnancy with conjoined twins is a very rare condition and is associated with many complications. CASE: In this study, we describe a monochorionic-diamniotic triplet pregnancy after in vitro fertilization with an intracytoplasmic sperm injection. At a gestational age of 6 weeks and 4 days of pregnancy one gestational sac was observed, and at a gestational age of 12 weeks and 2 days, triplets with conjoined twins were diagnosed...
November 2015: Iranian Journal of Reproductive Medicine
Tahir Abbas, Khawaja Raees Ahmad, Asmat Ullah, Samreen Iqbal, Kausar Raees
BACKGROUND: Precious fruits like jambul are neglected and wasted while environmental pollutants like lead intake remain overlooked. OBJECTIVE: The aim of this study was to investigate the effects of the Jambul pulp extract on lead detrimental effects in pseudostratified epithelium and the stereocilia of mice epididymis and vas deferens. MATERIALS AND METHODS: Thirty young males mice (Mus musculus) were distributed randomly in 3 groups (n= 10) called control, Pb (Lead) and Pb-J (Lead-Jambul)...
November 2015: Iranian Journal of Reproductive Medicine
Wang Dan, Gao Jing, Xia Liangbin, Zhang Ting, Zeng Ying
BACKGROUND: Poor ovarian response phenomenon has been observed in some of the in vitro fertilization-embryo transfer patients. Some investigations found that follicle stimulating hormone receptor ( FSHR ) gene plays a role in the process, but no direct evidence shows the correlation between genotypes of FSHR and ovarian response. OBJECTIVE: Exploring the molecular mechanism behind the mutation of FSH R promoter association with ovarian granulosa cells and poor ovarian response...
November 2015: Iranian Journal of Reproductive Medicine
Mohammad Reza Moein, Mahmoud Reza Moein, Jalal Ghasemzadeh, Soheila Pourmasoumi
BACKGROUND: About 10% to 15% of infertile men have azoospermia, which could be obstructive or non-obstructive. Diagnostic biopsy from the testis and recently testicular sperm extraction (TESE) are the most precise investigations in these patients. Testicular biopsy can be done unilaterally or bilaterally. The worth of unilateral or bilateral testicular biopsy in men with azoospermia is controversial. OBJECTIVE: To evaluate the necessity of bilateral diagnostic biopsy from the testis in new era of diagnosis and treatment of male infertility...
November 2015: Iranian Journal of Reproductive Medicine
Fatemeh Roodbari, Nahid Abedi, Ali Reza Talebi
BACKGROUND: There are few studies indicating the detrimental effects of ibuprofen on sperm fertility potential and DNA integrity. OBJECTIVE: To determine the effects of Ibuprofen on sperm parameters, chromatin condensation and DNA integrity of mice. MATERIALS AND METHODS: In this experimental study, 36 adult male mice with average weight 37 gr were divided into three groups, including control (group I, n=12), normal dosage of ibuprofen (group II, n=12) and high dosage (group III, n=12)...
November 2015: Iranian Journal of Reproductive Medicine
Maryam Khoshnood Shariati, Zohreh Karimi, Mahroo Rezaienejad, Azita Basiri, Farahnaze Torkestani, Soraya Saleh Gargari
BACKGROUND: Morbidity and mortality of preterm babies are important issues in perinatal medicine. In developed countries, preterm delivery is the cause of about 70% of mortality and 75% of morbidity in the neonatal period, respectively. OBJECTIVE: The aim of this study was to determine the risk factors for preterm labor and the outcomes, in terms of perinatal mortality and morbidity at the time of discharge home, among preterm infants at less than 34 weeks gestation...
November 2015: Iranian Journal of Reproductive Medicine
Mahdieh Mojibian, Sedigheh Soheilykhah, Mohammad Ali Fallah Zadeh, Maryam Jannati Moghadam
BACKGROUND: Vitamin D supplementation during pregnancy has been supposed to defend against adverse gestational outcomes. OBJECTIVE: This randomized clinical trial study was conducted to assess the effects of 50,000 IU of vitamin D every two weeks supplementation on the incidence of gestational diabetes (GDM), gestational hypertension, preeclampsia and preterm labor, vitamin D status at term and neonatal outcomes contrasted with pregnant women that received 400 IU vitamin D daily...
November 2015: Iranian Journal of Reproductive Medicine
Tayebeh Rastegar, Mehryar Habibi Roudkenar, Soraya Parvari, Maryam Baazm
BACKGROUND: Sertoli cells play a pivotal role in creating microenvironments essential for spermatogonial stem cells (SSCs) self-renewal and commitment to differentiation. Maintenance of SSCs and or induction of in vitro spermiogenesis may provide a therapeutic strategy to treat male infertility. OBJECTIVE: This study investigated the role of luekemia inhibitory factor (LIF) on the propagation of SSCs and both functions of Sertoli cells on the proliferation and differentiation of these cells...
November 2015: Iranian Journal of Reproductive Medicine
Behrouz Gharesi-Fard, Zahra Ghasemi, Saeed Shakeri, Shabnam Behdin, Fatemeh Aghaei, Zahra Malek-Hosseini
BACKGROUND: Azoospermia is the medical condition of a man not having any measurable level of sperm in his semen. Follicle stimulating hormone (FSH) is a member of the glycoprotein hormone family that plays an important role in human reproduction because of its essential role in normal spermatogenesis. Various Single Nucleotide Polymorphisms (SNPs) have been reported within FSH receptor (FSHR) gene that may affect the receptor function. OBJECTIVE: The present study aimed to investigate the correlation between two FSHR SNPs at positions A919G, A2039G, and susceptibility to azoospermia in a group of Iranian azoospermic men...
November 2015: Iranian Journal of Reproductive Medicine
Flávia Romariz Ferreira, Heloisa Regina Russo Akiba, E Araujo Júnior, Elisabeth Niglio Figueiredo, Anelise Riedel Abrahão
BACKGROUND: Some congenital defects can be prevented in the pregestational stage. However, many health professionals are not prepared to provide counselling to couples regarding the same. OBJECTIVE: This study aimed to assess the performance of doctors and nurses from a primary health-care unit in Florianopolis, Brazil, in preventing birth defects in the preconception period based on the recommendations of the Control Center of Disease Prevention. MATERIALS AND METHODS: This descriptive cross sectional study was performed at a tertiary referral center...
October 2015: Iranian Journal of Reproductive Medicine
Mahshid Bokaie, Masoumeh Simbar, Seyed Mojtaba Yassini Ardekani
BACKGROUND: Infertility makes an essential challenge to the sexual life of couples, especially infertile women. When pregnancy does not happen, infertile women think that sexual intercourse is not fruitful and sexual desire became reduce gradually. Infertile women progressively forget that their sexual relationship is also a response to their natural need. OBJECTIVE: This qualitative study was conducted to explore the infertility consequences in the sexual behavior of infertile women...
October 2015: Iranian Journal of Reproductive Medicine
Mohamed Shehata Ali Mohamed
BACKGROUND: Spermatozoa cryopreservation is used for the management of infertility and some other medical conditions. The routinely applied cryopreservation technique depends on permeating cryoprotectants, whose toxic effects have raised the attention towards permeating cryoprotectants-free vitrification technique. OBJECTIVE: To compare between the application of slow cryopreservation and vitrification on human spermatozoa. MATERIALS AND METHODS: This was an experimental controlled study involving 33 human semen samples, where each sample was divided into three equal parts; fresh control, conventional slow freezing, and permeating cryoprotectants-free vitrification...
October 2015: Iranian Journal of Reproductive Medicine
Fatemeh Shakarami, Mohammad Taghi Akbari, Shohreh Zare Karizi
BACKGROUND: Recurrent pregnancy loss (RPL) defined by two or more failed pregnancies before 20 weeks of gestation. Several factors play a role in RPL including thrombophilic conditions which can be influenced by gene polymorphisms. Plasminogen activator inhibitor-1 (PAI-1) and angiotensin converting enzyme (ACE) genes are closely related to fibrinolytic process, embryonic development and pregnancy success. OBJECTIVE: The aim of this study was to investigate the relationship between RPL and common polymorphisms in ACE and PAI-1 genes...
October 2015: Iranian Journal of Reproductive Medicine
Viorica E Radoi, Camil L Bohiltea, Roxana E Bohiltea, Dragos N Albu
BACKGROUND: The discovery of circulating fetal DNA in maternal blood led to the discovery of new strategies to perform noninvasive testing for prenatal diagnosis. OBJECTIVE: The purpose of the study was to detect fetal aneuploidy at chromosomes 13, 18, 21, X, and Y by analysis of fetal cell-free DNA from maternal blood, without endangering pregnancy. MATERIALS AND METHODS: This retrospective study has been performed in Bucharest at Medlife Maternal and Fetal Medicine Department between 2013-2014...
October 2015: Iranian Journal of Reproductive Medicine
Hamed Karami Shabankareh, Mohammad Hamed Shahsavari, Hadi Hajarian, Gholamali Moghaddam
BACKGROUND: Previous studies reported many discrepancies about the effects of corpus luteum (CL) and ovarian follicle size on the developmental competence of oocytes. OBJECTIVE: The aim of this study was to investigate the effects of CL and different size of follicle on the developmental potential of bovine oocytes. MATERIALS AND METHODS: After ovarian classification based on presence or absence of CL, sample follicles were placed in three groups according to their diameter; small (S; 3-6 mm), medium (M; 6-9 mm), and large (L; 10-20 mm)...
October 2015: Iranian Journal of Reproductive Medicine
Maryam Hormozi, Saeed Talebi, Hamid Reza Khorram Khorshid, Amir-Hassan Zarnani, Koorosh Kamali, Mahmood Jeddi-Tehrani, Haleh Soltangoraee, Mohammad Mehdi Akhondi
BACKGROUND: One of the promising methods in fertility preservation among women with cancer is cryopreservation of ovarian cortex but there are many drawbacks such as apoptosis and considerable reduction of follicular density in the transplanted ovary. One solution to reduce ischemic damage is enhancing angiogenesis after transplantation of ovarian cortex tissue. OBJECTIVE: The aim of this study was to investigate the effect of Setarud, on angiogenesis in transplanted human ovarian tissue...
October 2015: Iranian Journal of Reproductive Medicine
Anahita Jalilian, Faezeh Kiani, Fatemeh Sayehmiri, Kourosh Sayehmiri, Zahra Khodaee, Malihe Akbari
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age and is the most common cause of infertility due to anovulation. There is no single criterion for the diagnosis of this syndrome. OBJECTIVE: The purpose of this study was to investigate the prevalence of PCOS and its associated complications in Iranian women using meta-analysis method. MATERIALS AND METHODS: Prevalence of PCOS was investigated from the SID, Goggle scholar, PubMed, Magiran, Irandoc, and Iranmedex, and weighting of each study was calculated according to sample size and prevalence of the binomial distribution...
October 2015: Iranian Journal of Reproductive Medicine
Farahnaz Mardanian, Moones Kazeroonizadeh, Bahman Rashidi
BACKGROUND: Infertility is an increasing medical and social problem. In vitro fertilization (IVF) has become a common and accessible treatment for a wide variety of indications that have variable outcomes. Natural killer (NK) cells have been identified as relevant immunological factors involved in reproductive success or failure. OBJECTIVE: The aim of this study was to compare the percentage of peripheral blood CD56(+) (CD56(dim) and CD56(bright)) cells and the level of NK cell in patients with IVF failure with those of successful IVF control women...
September 2015: Iranian Journal of Reproductive Medicine
Shohreh Irani, Firoozeh Ahmadi, Maryam Javam, Ahmad Vosough Taghi Dizaj, Fatemeh Niknejad
BACKGROUND: Several studies have assessed the correlation of fetal choroid plexus cyst (CPC) and the risk of congenital anomalies, but few ones have discussed isolated CPC (with no other abnormal sonographic finding). OBJECTIVE: The aim of this study was to determine the outcome of isolated fetal choroid plexus cyst and to specify its clinical significance. MATERIALS AND METHODS: This cross sectional study was carried out at Royan Institute in Tehran, Iran, between April 2009 and December 2012...
September 2015: Iranian Journal of Reproductive Medicine
Majid Motovali-Bashi, Zahra Rezaei, Fariba Dehghanian, Halimeh Rezaei
BACKGROUND: Infertility is a health problem which affects about 10-20% of married couples. Male factor infertility is involved approximately 50% of infertile couples. Most of male infertility is regarding to deletions in the male-specific region of the Y chromosome. OBJECTIVE: In this study, the occurrence of deletions in the AZF region and association between infertility and paternal age were investigated in Iranian men population. MATERIALS AND METHODS: To assess the occurrence of Y chromosomal microdeletions and partial deletions of the AZF region, 100 infertile men and 100 controls with normal spermatogenesis were analyzed...
September 2015: Iranian Journal of Reproductive Medicine
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