Journal of the Turkish German Gynecological Association

OBJECTIVE: Osteoporosis is a substantial global public health issue. The objective of this study was to evaluate the risk variables related with osteoporosis among patients seeking care at an outpatient menopausal clinic in a tertiary university hospital. MATERIALS AND METHODS: In this retrospective cross-sectional study a total of 1148 postmenopausal women who applied to the outpatient menopause clinic of the Başkent University Hospital between June 01, 2014, and August 31, 2015, were enrolled...

OBJECTIVE: Ultrasonography is an acceptable tool to diagnose the placenta accreta spectrum (PAS) among pregnant women; however, the lack of a strong criteria protocol in diagnosis and predicting the severity of the consequences facing pregnant women requires novel markers investigation. MATERIAL AND METHODS: This prospective cross-sectional study was performed on pregnant women with a probable diagnosis of PAS. Therefore, 51 pregnant women were involved in the study...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

Gestational trophoblastic neoplasia (GTN) arising in the placenta and presenting as a metastatic disease concurrently in the mother and the baby is extremely rare. GTN poses a diagnostic dilemma to the treating clinicians. In the current review, an electronic search of Scopus, PubMed, Embase and other databases was conducted for case reports and case series of GTN co-existing or metastatic to both the mother and the baby, published to date. Globally, a total of twenty-two cases of GTN with metastasis to both the mother and baby was found...

OBJECTIVE: Proper deactivation of the pluripotency network and activation of a lineage-specific gene expression program are critical for mouse embryonic stem cell (mESC) differentiation. This is achieved by the coordinated action of transcription and chromatin factors. Our previous work identified ARID4B as a critical chromatin factor for mesoderm and endoderm differentiation. As part of a histone deacetylase complex, ARID4B plays a role in transcriptional suppression of its direct targets...

OBJECTIVE: The aim of the study was to test validity and reliability of the Human Papilloma Virus Knowledge Scale (HPV-KS) in Turkish. MATERIAL AND METHODS: The methodological study was conducted with 920 participants at a training and research hospital in Ankara, Turkey, between February and May 2019. The data collection form consisted of descriptive characteristics of the participants and HPV-KS. Guidelines for the Process of Cross-Cultural Adaptation of Self-Reported Measures were followed for the language and cultural adaptation of the scale...

OBJECTIVE: To evaluate the oncologic outcomes of endometrial cancer metastasis to the adrenal gland and kidney, based on a case study and review of the literature. MATERIAL AND METHODS: A systematic review of the medical literature was performed to identify articles about metastatic endometrial cancer to the adrenal gland and kidney from 1975 until 2021. RESULTS: A 55-year-old female patient was admitted to our center. On pelvic examination, a mass protruding out of the cervix was observed, which was shown to be endometrioid carcinoma on biopsy...

OBJECTIVE: To investigate the clinical significance of a diagnosis of chronic endometritis (CE) made using a diagnostic cut-off of ≥1 or ≥5 CD138 plasma cells per high power field (HPF) in asymptomatic patients undergoing in vitro fertilization (IVF) with frozen embryo transfer (FET). MATERIAL AND METHODS: In this retrospective case-control study, 1,865 patients underwent freeze-all-IVF treatment between January and December 2019, with 419 undergoing endometrial biopsies at oocyte retrieval...

OBJECTIVE: The purpose was to evaluate the effectiveness of a non-invasive prenatal test (NIPT) using mass parallel sequencing (MPS) to detect trisomy 13, 18, 21 and fetal sex chromosome abnormalities in maternal blood samples by isolating freely circulating foetal extracellular DNA (eDNA), and to develop an algorithm for prenatal screening. MATERIAL AND METHODS: The research methods used included blood sampling from patients, isolation of eDNA, determination of DNA concentration and quality, library preparation for sequencing, MPS using an Illumina HiSeq2000, positive and negative control samples, monitoring, and analysis of results using the distributed algorithms platform based on calculations of z-value and the average absolute deviation...

OBJECTIVE: To compare laparoscopic pectopexy with the standard laparoscopic sacropexy in women with symptomatic apical prolapse. MATERIAL AND METHODS: An interim analysis of an exploratory randomized controlled trial with the primary objective of comparing mesh fixation time and secondary objectives were to compare total operating time, blood loss, and intra-operative and post-operative complications. Additionally, patients completed the Prolapse Quality of Life (P-QOL) and Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) questionnaires before surgery and during six months follow-up visit to evaluate the overall improvement in quality of life and sexual function...

OBJECTIVE: Repeated blood transfusions in women with Beta-thalassemia major (BTM) may lead to iron overload and increase oxidative stress and consequently resulting in ovarian damage. We aimed to evaluate the alterations in the ovarian reserve of transfusion-dependent BTM patients over a time period of one year and compared the anti-mullerian hormone (AMH) levels between women with BTM and healthy population. MATERIAL AND METHODS: This longitudinal prospective study was conducted in 41 women with transfusion-dependent BTM at the tertiary hospital...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

The effects of diet and nutritional habits on reproductive cells can be categorized in a variety of ways. In this review, the literature is divided, based on the dietary consumption effects on oocytes and sperm. Topics on dietary patterns and the intrauterine effect of maternal nutrition are covered. In general fruits, vegetables, whole greens, fish, legumes, and also dietary sources containing unsaturated fats can improve reproductive germ cell quality. In epidemiological studies, the food intake frequency questionnaire is one of the most common methods to assess diet...

OBJECTIVE: To investigate maternal adverse effects and perinatal and neonatal outcomes of women receiving coronavirus disease-2019 (COVID-19) vaccination during pregnancy. MATERIAL AND METHODS: Seven hundred and sixty pregnant women who were followed up in obstetrics outpatients were included in this prospective cohort study. COVID-19 vaccination and infection histories of the patients were recorded. Demographic data, including age, parity, and presence of systemic disease and adverse events following COVID-19 vaccination were recorded...

Classification of endometrial carcinomas based on solely histological features is not sufficient for prognostic and therapeutic guidance of patients. The presence of endometrial carcinomas in which the histological type cannot also be determined clearly and the poor reproducibility of the histological typing lead difficulties on the management of these patients. Molecular classification is very promising due to its high reproducibility and good correlation with clinical outcome of the endometrial carcinoma...

OBJECTIVE: The aim of this study was to determine the Standard mid-trimester cervical lengths of singleton and twin pregnancies. MATERIAL AND METHODS: This study was conducted by retrospective analysis of mid-trimester transvaginal cervical measurements of women with singleton and twin pregnancies that were examined by a single perinatologist in a single center. RESULTS: A total of 4621 consecutive asymptomatic pregnant women admitting for advanced obstetric ultrasound screening were evaluated...

OBJECTIVE: To describe the technique and assess long term effects of neurovascular bundle sparing adult clitoroplasty on clitoral functions in adult patients. MATERIAL AND METHODS: A case series study enrolling 3 patients diagnosed with adult clitoromegaly who underwent neurovascular bundle sparing ventral clitoroplasty operation. All of the patients were examined on the 1st , 3rd , 6th , 12th and 24th months to evaluate postoperative clitoral functions. RESULTS: Three patients diagnosed with adult clitoromegaly aged 17, 21 and 24 were enrolled in the study...