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Obstetrics & Gynecology Science

Minhee Lee, Tae Hee Kim, Se Jeong Kim, Byung Chul Jee
Posterior reversible encephalopathy syndrome (PRES) is a newly described adverse effect possibly associated with gonadotropin-releasing hormone (GnRH) agonist therapy. We report a case of PRES after 2 doses of depot GnRH agonists in a 44-year-old woman with a huge myoma uteri and iron-deficiency anemia. Brain magnetic resonance imaging showed high signal lesions in both occipital lobes on fluid-attenuated inversion-recovery (FLAIR) images, compatible with PRES. After treatment with anticonvulsant, she recovered both radiographically and clinically...
January 2019: Obstetrics & Gynecology Science
Ji-Eun Park, Mi Ju Kim, Min Kyoung Kim, Hyun Mi Kim
Cervical varix is rare and can develop due to various conditions in pregnancy. Most cases of cervical varix during pregnancy are diagnosed in the second or third trimester and are usually associated with abnormal placental location, such as placenta previa or low-lying placenta. A 23-year-old woman with cervical varix bleeding visited our institution at 8 weeks of gestation. This case report describes cervical varix bleeding that developed into a venous thrombus in the first trimester. Ultrasonography with color Doppler and magnetic resonance imaging could be helpful in diagnosis...
January 2019: Obstetrics & Gynecology Science
Su Hyeon Choi, Soyeon Hong, Miseon Kim, Hyo Sook Bae, Mi Kyoung Kim, Mi-La Kim, Yong Wook Jung, Bo Seong Yun, Seok Ju Seong
Objective: To evaluate the feasibility of robotic single-site myomectomy (RSSM). Methods: Medical records of 355 consecutive women who underwent robotic-assisted laparoscopic myomectomy were retrospectively reviewed. Clinical characteristics were compared between multi-site and single-site systems. After 1:1 propensity score matching for the total myoma number, largest myoma size, and total tumor weight (105 women in each group), surgical outcomes were also compared between the 2 systems...
January 2019: Obstetrics & Gynecology Science
Hyun Hye Lim, Yun Ha Jang, Gyu Yeon Choi, Jeong Jae Lee, Eun Sil Lee
Objective: To investigate the clinical characteristics and medical management of transgender people in South Korea. Methods: The electronic medical records of 54 transgender persons who had visited Soonchunhyang University Hospital from January 2016 to December 2017 for medical care were retrospectively reviewed. We identified patient demographics and gender identity-related characteristics. Moreover, we compared our hospital protocol with official guidelines. Results: At the time of the medical record search, the average age of these 52 transgender persons was 27 years, and 46 (88...
January 2019: Obstetrics & Gynecology Science
Myung-Hwa Jeong, Hyungjoo Kim, Tae-Hun Kim, Moon-Hong Kim, Beob-Jong Kim, Sang-Young Ryu
Objective: This study aimed to evaluate the prognostic impact of age at diagnosis, and pretreatment hematologic markers, including lymphocyte percentage and the neutrophil-to-lymphocyte ratio (NLR), in patients with locally advanced cervical cancer (LACC) treated with definitive radiotherapy (RT). Methods: A total of 392 patients with LACC (stage IIb to IVa) treated with cisplatin-based concurrent chemoradiotherapy or RT alone between 2001 and 2012 were retrospectively enrolled...
January 2019: Obstetrics & Gynecology Science
Joo-Hyuk Son, Seokyoung Yoon, Seokyung Kim, Tae-Wook Kong, Jiheum Paek, Suk-Joon Chang, Hee-Sug Ryu
Objective: This study aimed to analyze the clinical features of clear cell carcinoma in relation to endometriosis and to determine an appropriate surveillance strategy for the early detection of malignant transformation of endometrioma in asymptomatic patients. Methods: We retrospectively reviewed the clinicopathologic data of 50 patients with ovarian clear cell carcinoma. Clinicopathologic characteristics, treatment outcomes, and the association between endometriosis and the risk of malignant transformation were analyzed...
January 2019: Obstetrics & Gynecology Science
Hye In Kim, Sung Pil Choo, Sang Won Han, Eui Hyeok Kim
Objective: To critically compare the benefits and risks of labor induction versus spontaneous labor in uncomplicated nulliparous women at 39 or more weeks of gestation. Methods: We conducted a retrospective, observational study of 237 nulliparous women who were at 39 or more weeks of a singleton pregnancy with vertex presentation and intact membranes. We compared maternal outcomes including the Cesarean section rate and neonatal outcomes in the induced labor and spontaneous labor groups...
January 2019: Obstetrics & Gynecology Science
Hye In Kim, SeonMi Nam, Yejin Park, Yun Ji Jung, Ha Yan Kim, Kyung Won Kim, Myung Hyun Sohn, Young-Han Kim, Joon-Ho Lee, Soo Jong Hong, Ja-Young Kwon
Objective: In this study, we evaluated the prevalence of allergic disease in offsprings delivered via the delivery modes of vaginal delivery vs. planned Cesarean section vs. Cesarean section with labor. Methods: This study included 175 mother-neonate pairs from Severance Hospital who were enrolled in the Cohort for Childhood Origin of Asthma and allergic diseases study. Information regarding prenatal environmental factors, delivery, and diagnosis of allergic diseases was obtained from a questionnaire and medical record review...
January 2019: Obstetrics & Gynecology Science
Hyun Jong Park, Hannah Kim, Geun Ho Lee, Tae Ki Yoon, Woo Sik Lee
Endometriosis is a chronic inflammatory condition that affects fertility and could be toxic to the ovary. Endometrioma per se and surgical interventions for endometrioma significantly reduce the ovarian reserve. Therefore, to prepare for surgical intervention for endometrioma, the high-risk group with decreased ovarian reserve must be considered. There is no evidence to support the use of surgical intervention before in vitro fertilization (IVF) to improve the reproductive outcomes of subsequent IVF in infertile women with advanced-stage endometriosis or endometrioma...
January 2019: Obstetrics & Gynecology Science
Miseon Kim, Young-Han Kim, Yong Beom Kim, Jayeon Kim, Jae-Weon Kim, Mi Hye Park, Joo Hyun Park, Jeong Ho Rhee, Myong Cheol Lim, Joon-Seok Hong
[This corrects the article on p. 542 in vol. 61, PMID: 30254990.].
November 2018: Obstetrics & Gynecology Science
Chul Kwon Lim, Hee Jin Kim, Joon Sook Pack, Joong Gyu Ha, Yun Seok Yang, Hye Kyung Lee, Seung Hyun Kim
A supernumerary ovary is a rare gynecological anomaly, and is usually excised due to its malignant transformation potential. We report a case of a supernumerary ovary and endometriosis situated on the anterior rectosigmoid colon. When laparoscopy was conducted, a firm, 5-cm mass was discovered on the anterior rectosigmoid colon along with normal ovaries. In this case, the discovery of a supernumerary ovary implied the presence of endometriosis. It is unusual for endometriosis and a supernumerary ovary to exist simultaneously...
November 2018: Obstetrics & Gynecology Science
Rashi Garg, Neelam Gupta
We report a rare case of vaginal amelanotic melanoma. Malignant melanomas are cutaneous and extracutaneous tumors that arise from embryological remnants of neural crest cells/melanocytes. Amelanotic melanomas at such rare locations can be misdiagnosed both clinically and radiologically. Therefore, histopathological examination and immunohistochemistry are mandatory for the diagnosis of these tumors. We diagnosed this case using histopathology and confirmed the diagnosis based on the presence of immunohistochemical markers human melanoma black 45 (HMB45) and S-100...
November 2018: Obstetrics & Gynecology Science
Scott R Kelley
Aggressive angiomyxoma (AA) is a very rare mesenchymal tumor most commonly found in the pelvic and perineal regions. For the complete excision of retrorectal tumors, with extension through the levator muscle into the ischioanal space, open anterior and posterior approaches are typically required. Herein, we report our experience with robotic excision of a giant presacral AA with extralevator extension into the ischioanal space and extraction via Pfannenstiel incision, which we found to be technically feasible, efficacious, and safe to perform...
November 2018: Obstetrics & Gynecology Science
Ji Hyun Park, Jung Hwan Ahn, Kyung Jin Seo, Sae Kyung Choi, In Yang Park, Yeon-Hee Kim
Listeriosis is a rare foodborne infection caused by Listeria monocytogenes . It is 12-20 times more prevalent in pregnant women compared to the general population, with a 20-40% mortality rate in neonates. Early treatment with appropriate antimicrobial agents is critical for pregnancy outcomes; however, the infection is difficult to control because the nonspecific clinical manifestations and rarity of the disease often preclude early diagnosis. We encountered 2 cases of pregnancy-associated listeriosis that occurred at 29 and 37 weeks of gestation...
November 2018: Obstetrics & Gynecology Science
Fatemeh Shobeiri, Sasan Nazari, Saman Nazari, Ensiyeh Jenabi, Arezoo Shayan
Objective: Primary dysmenorrhea occurs in more than 50% of women of reproductive age. This survey evaluated the effects of Menstrugole on the alleviation of primary dysmenorrhea. Methods: This study was performed in western Iran between August 15 and December 15, 2017, in female students with primary dysmenorrhea. The students were randomly divided into 2 groups and received placebo or a Menstrugole capsule for 3 days in each of 2 menstrual cycles. The visual analog scale was used to assess pain severity...
November 2018: Obstetrics & Gynecology Science
Suyeon Park, Young-Eun Lee, Seong-Sik Cho, Sung-Ho Park, Sung Taek Park
Objective: This study aimed to evaluate patient-reported satisfaction following robot-assisted hysterectomy due to benign uterine disease, and to identify the factors associated. Methods: We used a questionnaire to evaluate patients' satisfaction with robot-assisted hysterectomy. The questions concerned overall patient-reported satisfaction and specific factors affecting satisfaction, including postoperative pain, return to daily life, the hospital experience, wounds, cost, the doctor-patient relationship, whether expectations were met, and whether detailed information was provided...
November 2018: Obstetrics & Gynecology Science
Seul Ki Kim, Hyein Kim, Soohyun Oh, Jung Ryeol Lee, Byung Chul Jee, Seok Hyun Kim
Objective: This study aimed to develop a nomogram that predicts ongoing pregnancy after in vitro fertilization and embryo transfer (IVF-ET) using patient age and serum hormonal markers. Methods: A total of 284 IVF-ET cycles were retrospectively analyzed. At 14 days post-oocyte pick-up (OPU), the serum human chorionic gonadotropin (HCG) and progesterone levels were measured. The main predicted outcome was ongoing pregnancy. Results: Patient age and serum of HCG and progesterone levels at 14 days post-OPU were good predictors of ongoing pregnancy...
November 2018: Obstetrics & Gynecology Science
Kyeong A So, Seon Ah Kim, Yoo Kyung Lee, In Ho Lee, Ki Heon Lee, Jee Eun Rhee, Mee Kyung Kee, Chi Heum Cho, Sung Ran Hong, Chang Sun Hwang, Mi Seon Jeong, Ki Tae Kim, Moran Ki, Soo Young Hur, Jong Sup Park, Tae Jin Kim
Objective: This study was to identify the risk factors for cytological progression in women with atypical squamous cells of undetermined significance (ASC-US) or low-grade squamous intraepithelial lesions (LSIL). Methods: We analyzed data from women infected with the human papillomavirus (HPV) who participated in the Korean HPV cohort study. The cohort recruited women aged 20-60 years with abnormal cervical cytology (ASC-US or LSIL) from April 2010. All women were followed-up at every 6-month intervals with cervical cytology and HPV DNA testing...
November 2018: Obstetrics & Gynecology Science
Anubhuti Rana, Krishna Agarwal, Siddarth Ramji, Gauri Gandhi, Latika Sahu
Objective: There is concern regarding the safety of delayed cord clamping (DCC) in babies born at less than 34 weeks' gestation. Therefore, the primary objective of this study was to compare the rates of hyperbilirubinemia and polycythemia during initial 7 days in infants born at less than 34 weeks' gestation and randomized to receive DCC by 120 seconds or early cord clamping (ECC) within less than 30 seconds. Methods: One hundred pregnant women were randomly subjected to DCC or ECC at the time of birth in a tertiary referral hospital setting...
November 2018: Obstetrics & Gynecology Science
Nae Ry Kim, So Ra Yoon, June Seek Choi, Hyun Kyong Ahn, So-Young Lee, Dal Soo Hong, Jeong Sup Yun, Seong Yeon Hong, Yoon Ha Kim, Jung Yeol Han
Objective: Isotretinoin is a notorious teratogen otherwise used for the treatment of acne vulgaris. Some countries, including those in North America and the European Union, implemented the pregnancy prevention program (PPP); however, no PPP has yet been established in South Korea. So the aim of this study was to evaluate the rate of pregnant women exposed to isotretinoin among the callers of the Korean Mother Safe Counseling Center. Methods: This is a prospective cohort study...
November 2018: Obstetrics & Gynecology Science
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