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JOURNAL ARTICLE
Jong-Su Kim, Eung-Joon Lee, Han-Yeong Jeong, Keun-Hwa Jung
No abstract text is available yet for this article.
September 6, 2023: Journal of Stroke
#2
JOURNAL ARTICLE
Minyoul Baik, Chi Young Shim, Seo-Yeon Gwak, Young Dae Kim, Hyo Suk Nam, Soyoung Jeon, Hye Sun Lee, Ji Hoe Heo
No abstract text is available yet for this article.
September 6, 2023: Journal of Stroke
#3
JOURNAL ARTICLE
Lu Wang, Ying-Jie Dai, Yu Cui, Hong Zhang, Chang-Hao Jiang, Ying-Jie Duan, Yong Zhao, Ye-Fang Feng, Shi-Mei Geng, Zai-Hui Zhang, Jiang Lu, Ping Zhang, Li-Wei Zhao, Hang Zhao, Yu-Tong Ma, Cheng-Guang Song, Yi Zhang, Hui-Sheng Chen
BACKGROUND AND PURPOSE: Intravenous tenecteplase (TNK) efficacy has not been well demonstrated in acute ischemic stroke (AIS) beyond 4.5 hours after onset. This study aimed to determine the effect of intravenous TNK for AIS within 4.5 to 24 hours of onset. METHODS: In this pilot trial, eligible AIS patients with diffusion-weighted imaging (DWI)-fluid attenuated inversion recovery (FLAIR) mismatch were randomly allocated to intravenous TNK (0.25 mg/kg) or standard care within 4...
August 24, 2023: Journal of Stroke
#4
JOURNAL ARTICLE
Chunrong Tao, Guangxiong Yuan, Pengfei Xu, Hao Wang, Peiyang Zhou, Tingyu Yi, Kai Li, Tao Cui, Jun Gao, Rui Li, Jun Sun, Chao Zhang, Li Wang, Tianlong Liu, Jianlong Song, Yamei Yin, Thanh N Nguyen, Qing Li, Wei Hu
BACKGROUND AND PURPOSE: To examine the clinical and safety outcomes after endovascular treatment (EVT) for acute basilar artery occlusion (BAO) with different anesthetic modalities. METHODS: This was a retrospective analysis using data from the Endovascular Treatment for Acute Basilar Artery Occlusion (ATTENTION) registry. Patients were divided into two groups defined by anesthetic modality performed during EVT: general anesthesia (GA) or non-general anesthesia (non-GA)...
August 23, 2023: Journal of Stroke
#5
JOURNAL ARTICLE
Milagros Galecio-Castillo, Mudassir Farooqui, Ameer E Hassan, Mouhammad A Jumaa, Afshin A Divani, Marc Ribo, Michael Abraham, Nils H Petersen, Johanna T Fifi, Waldo R Guerrero, Amer M Malik, James E Siegler, Thanh N Nguyen, Sunil Sheth, Albert J Yoo, Guillermo Linares, Nazli Janjua, Darko Quispe-Orozco, Wondwossen Tekle, Syed F Zaidi, Sara Y Sabbagh, Marta Olivé-Gadea, Tiffany Barkley, Reade De Leacy, Kenyon W Sprankle, Mohamad Abdalkader, Sergio Salazar-Marioni, Jazba Soomro, Weston Gordon, Charoskhon Turabova, Juan Vivanco-Suarez, Aaron Rodriguez-Calienes, Maxim Mokin, Dileep R Yavagal, Tudor Jovin, Santiago Ortega-Gutierrez
BACKGROUND AND PURPOSE: Effect of endovascular therapy (EVT) in acute large vessel occlusion (LVO) patients with tandem lesions (TLs) within 6-24 hours after last known well (LKW) remains unclear. We evaluated the clinical and safety outcomes among TL-LVO patients treated within 6-24 hours. METHODS: This multicenter cohort was divided into two groups, based on LKW to puncture time: early window (<6 hours), and late window (6-24 hours). Primary clinical and safety outcomes were 90-day functional independence measured by the modified Rankin Scale (mRS: 0-2) and symptomatic intracranial hemorrhage (sICH)...
August 23, 2023: Journal of Stroke
#6
JOURNAL ARTICLE
Eun-Jae Lee, Dongho Kim, Yong-Hwan Kim, Eun Namgung, Jee-Hyun Lee, Yuka Sasaki, Takeo Watanabe, Dong-Wha Kang
No abstract text is available yet for this article.
August 10, 2023: Journal of Stroke
#7
JOURNAL ARTICLE
Gabriela Trifan, Linda C Gallo, Melissa Lamar, Olga Garcia-Bedoya, Krista M Perreira, Amber Pirzada, Gregory A Talavera, Sylvia W Smoller, Carmen R Isasi, Jianwen Cai, Martha L Daviglus, Fernando D Testai
BACKGROUND AND PURPOSE: Social determinants of health (SDOH) are non-medical factors that may contribute to the development of diseases, with a higher representation in underserved populations. Our objective is to determine the association of unfavorable SDOH with self-reported stroke/transient ischemic attack (TIA) and vascular risk factors (VRFs) among Hispanic/Latino adults living in the US. METHODS: We used cross-sectional data from the Hispanic Community Health Study/Study of Latinos...
August 10, 2023: Journal of Stroke
#8
JOURNAL ARTICLE
Adriano Bonura, Francesco Motolese, Fioravante Capone, Gianmarco Iaccarino, Michele Alessiani, Mario Ferrante, Rosalinda Calandrelli, Vincenzo Di Lazzaro, Fabio Pilato
No abstract text is available yet for this article.
May 2023: Journal of Stroke
#9
JOURNAL ARTICLE
Olivier Godefroy, Mélanie Barbay, Jeanne Martin, Trevor Shields, Chantal Lamy, Audrey Courselle-Arnoux, Sandrine Canaple, Claire Leclercq, Martine Roussel, Marc-Etienne Meyer, Etienne Marchal, Frank A Wollenweber
No abstract text is available yet for this article.
May 2023: Journal of Stroke
#10
JOURNAL ARTICLE
Jong S Kim, Kyung-Bok Lee, Dae-Il Chang, Jae-Kwan Cha, Ji Sung Lee
No abstract text is available yet for this article.
May 2023: Journal of Stroke
#11
JOURNAL ARTICLE
Hiroyuki Kawano, Yuko Honda, Takashi Johno, Hibiku Maruoka, Kaoru Nakanishi, Mikito Saito, Kensuke Ogata, Atsushi Yamamichi, Ayane Kawatake, Teruyuki Hirano
No abstract text is available yet for this article.
May 2023: Journal of Stroke
#12
JOURNAL ARTICLE
Setareh Salehi Omran, Liqi Shu, Allison Chang, Neal S Parikh, Adeel S Zubair, Alexis N Simpkins, Mirjam R Heldner, Arsany Hakim, Sami Al Kasab, Thanh Nguyen, Piers Klein, Eric D Goldstein, Maria Cristina Vedovati, Maurizio Paciaroni, David S Liebeskind, Shadi Yaghi, Shawna Cutting
BACKGROUND AND PURPOSE: Vessel recanalization after cerebral venous thrombosis (CVT) is associated with favorable outcomes and lower mortality. Several studies examined the timing and predictors of recanalization after CVT with mixed results. We aimed to investigate predictors and timing of recanalization after CVT. METHODS: We used data from the multicenter, international AntiCoagulaTION in the Treatment of Cerebral Venous Thrombosis (ACTION-CVT) study of consecutive patients with CVT from January 2015 to December 2020...
May 2023: Journal of Stroke
#13
JOURNAL ARTICLE
Ghada A Mohamed, Raul G Nogueira, Muhammed Amir Essibayi, Hassan Aboul-Nour, Mahmoud Mohammaden, Diogo C Haussen, Aldo Mendez Ruiz, Bradley A Gross, Okkes Kuybu, Mohamed M Salem, Jan-Karl Burkhardt, Brian Jankowitz, James E Siegler, Pratit Patel, Taryn Hester, Santiago Ortega-Gutierrez, Mudassir Farooqui, Milagros Galecio-Castillo, Thanh N Nguyen, Mohamad Abdalkader, Piers Klein, Jude H Charles, Vasu Saini, Dileep R Yavagal, Ammar Jumah, Ali Alaraj, Sophia Peng, Muhammad Hafeez, Omar Tanweer, Peter Kan, Jacopo Scaggiante, Stavros Matsoukas, Johanna T Fifi, Stephan A Mayer, Alex B Chebl
BACKGROUND AND PURPOSE: Randomized trials proved the benefits of mechanical thrombectomy (MT) for select patients with large vessel occlusion (LVO) within 24 hours of last-known-well (LKW). Recent data suggest that LVO patients may benefit from MT beyond 24 hours. This study reports the safety and outcomes of MT beyond 24 hours of LKW compared to standard medical therapy (SMT). METHODS: This is a retrospective analysis of LVO patients presented to 11 comprehensive stroke centers in the United States beyond 24 hours from LKW between January 2015 and December 2021...
May 2023: Journal of Stroke
#14
JOURNAL ARTICLE
Christopher Traenka, Johannes Lorscheider, Christian Hametner, Philipp Baumgartner, Jan Gralla, Mauro Magoni, Nicolas Martinez-Majander, Barbara Casolla, Katharina Feil, Rosario Pascarella, Panagiotis Papanagiotou, Annika Nordanstig, Visnja Padjen, Carlo W Cereda, Marios Psychogios, Christian H Nolte, Andrea Zini, Patrik Michel, Yannick Béjot, Andreas Kastrup, Marialuisa Zedde, Georg Kägi, Lars Kellert, Hilde Henon, Sami Curtze, Alessandro Pezzini, Marcel Arnold, Susanne Wegener, Peter Ringleb, Turgut Tatlisumak, Paul J Nederkoorn, Stefan T Engelter, Henrik Gensicke
BACKGROUND AND PURPOSE: This study aimed to investigate the effect of endovascular treatment (EVT, with or without intravenous thrombolysis [IVT]) versus IVT alone on outcomes in patients with acute ischemic stroke (AIS) and intracranial large vessel occlusion (LVO) attributable to cervical artery dissection (CeAD). METHODS: This multinational cohort study was conducted based on prospectively collected data from the EVA-TRISP (EndoVAscular treatment and ThRombolysis for Ischemic Stroke Patients) collaboration...
May 2023: Journal of Stroke
#15
JOURNAL ARTICLE
Mengmeng Wang, Zhizhong Zhang, Marios K Georgakis, Ville Karhunen, Dandan Liu
BACKGROUND AND PURPOSE: We performed a two-sample Mendelian randomization (MR) analysis to evaluate the causal effect of genetically proxied AMP-activated protein kinase (AMPK) activation, which is the target of metformin, on functional outcome following ischemic stroke onset. METHODS: A total of 44 AMPK-related variants associated with HbA1c (%) were used as instruments for AMPK activation. The primary outcome was the modified Rankin Scale (mRS) score at 3 months following the onset of ischemic stroke, evaluated as a dichotomous variable (3-6 vs...
May 2023: Journal of Stroke
#16
REVIEW
Saurav Das, Liqi Shu, Rebecca J Morgan, Asghar Shah, Fayez H Fayad, Eric D Goldstein, Dalia Chahien, Benton Maglinger, Satish Kumar Bokka, Cory Owens, Mehdi Abbasi, Alexandra Kvernland, James E Siegler, Brian Mac Grory, Thanh N Nguyen, Karen Furie, Pooja Khatri, Eva Mistry, Shyam Prabhakaran, David S Liebeskind, Jose G Romano, Adam de Havenon, Lina Palaiodimou, Georgios Tsivgoulis, Shadi Yaghi
BACKGROUND AND PURPOSE: Intracranial arterial stenosis (ICAS)-related stroke occurs due to three primary mechanisms with distinct infarct patterns: (1) borderzone infarcts (BZI) due to impaired distal perfusion, (2) territorial infarcts due to distal plaque/thrombus embolization, and (3) plaque progression occluding perforators. The objective of the systematic review is to determine whether BZI secondary to ICAS is associated with a higher risk of recurrent stroke or neurological deterioration...
May 2023: Journal of Stroke
#17
REVIEW
Rami Z Morsi, Mohamed Elfil, Hazem S Ghaith, Mohammad Aladawi, Ahmad Elmashad, Sachin Kothari, Harsh Desai, Shyam Prabhakaran, Fawaz Al-Mufti, Tareq Kass-Hout
BACKGROUND AND PURPOSE: New studies have shown that endovascular thrombectomy (EVT) is safe and effective for acute ischemic stroke (AIS) patients with large ischemic areas. The aim of our study is to conduct a living systematic review and meta-analysis of randomized trials comparing EVT versus medical management only. METHODS: We searched MEDLINE, Embase, and the Cochrane Library to identify randomized controlled trials (RCTs) comparing EVT versus medical management alone in AIS patients with large ischemic regions...
May 2023: Journal of Stroke
#18
JOURNAL ARTICLE
Oh Young Bang, Eun Hee Kim, Mi Jeong Oh, Jaein Yoo, Gyun Sik Oh, Jong-Won Chung, Woo-Keun Seo, Gyeong-Moon Kim, Myung-Ju Ahn, Seong Wook Yang
BACKGROUND AND PURPOSE: This study aimed to evaluate whether extracellular-vesicle-incorporated microRNAs (miRNAs) are potential biomarkers for cancer-related stroke. METHODS: This cohort study compared patients with active cancer who had embolic stroke of unknown sources (cancer-stroke group) with patients with only cancer, patients with only stroke, and healthy individuals (control groups). The expression profiles of miRNAs encapsulated in plasma exosomes and microvesicles were evaluated using microarray and validated using quantitative real-time polymerase chain reaction...
May 2023: Journal of Stroke
#19
JOURNAL ARTICLE
Keun-Sik Hong, Oh Young Bang, Jong-Ho Park, Jin-Man Jung, Sang-Hun Lee, Tae-Jin Song, Hyo Suk Nam, Hee-Kwon Park, Keun-Hwa Jung, Sung Hyuk Heo, Jaseong Koo, Kyung-Ho Yu, Kwang-Yeol Park, Chi Kyung Kim, Hong-Kyun Park, Jiyoon Lee, Juneyoung Lee, Woo-Keun Seo
BACKGROUND AND PURPOSE: Moderate-intensity statin plus ezetimibe versus high-intensity statin alone may provide a greater low-density lipoprotein cholesterol (LDL-C) reduction in patients with recent ischemic stroke. METHODS: This randomized, open-label, controlled trial assigned patients with recent ischemic stroke <90 days to rosuvastatin/ezetimibe 10/10 mg once daily (ROS10/EZT10) or to rosuvastatin 20 mg once daily (ROS20). The primary endpoint was LDL-C reduction ≥50% from baseline at 90 days...
May 2023: Journal of Stroke
#20
REVIEW
Oh Young Bang, Kyoung-Min Park, Dong Seop Jeong
Atrial fibrillation (AF) is a leading cause of cardioembolic stroke, which is often fatal or disabling. Prevention of stroke is crucial in AF management, and anticoagulation with non-vitamin K oral anticoagulants (NOACs) is the mainstay of AF management for stroke prevention. Because NOAC prescriptions have been surging worldwide, the development of acute ischemic stroke in patients with AF who receive NOAC treatment is an increasingly important issue in clinical practice. Moreover, these patients show a high risk of recurrence, with more than a 50% higher risk, than do patients with AF and no prior anticoagulation therapy...
May 2023: Journal of Stroke
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