Phuong Anh Ton Nu, Thi Minh Chau Ngo, Cao Le Chi, Thị Bich Thao Do, Giang Tran Thi, Thị Ngoc Thuy Ha, Phuoc Vinh Nguyen, Minh Tam Le
Candida nivariensis is emerging as a highly resistant species of the Candida glabrata complex causing invasive and mucocutaneous infections. In this study, three cases of vulvovaginal candidiasis caused by C. nivariensis are described and identified by Internal Transcribed Spacer 1-2 sequencing. All isolates were susceptible in vitro to anidulafungin, micafungin, caspofungin, 5-flucytosine, posaconazole, voriconazole, itraconazole, amphotericin B, and showed dose-dependent susceptibility to fluconazole. In two patients, three doses of oral fluconazole were effective, while one patient developed clinical fluconazole resistance with a new relapse after 6 months...
March 2024: Medical Mycology Case Reports