journal
https://read.qxmd.com/read/38606206/do-hospitalizations-push-households-into-poverty-in-india-evidence-from-national-data
#1
JOURNAL ARTICLE
Shyamkumar Sriram, Muayad Albadrani
INTRODUCTION: High percentage of OOP (Out-of-Pocket) costs can lead to poverty and exacerbate existing poverty, with 21.9% of India's 1.324 billion people living below the poverty line. Factors such as increased patient cost-sharing, high-deductible health plans, and expensive medications contribute to high OOP costs. Understanding the poverty-inducing impact of healthcare payments is essential for formulating effective measures to alleviate it. METHODS: The study used data from the 75th round of the National Sample Survey Organization (Household Social Consumption in India: Health) from July 2017-June 2018, focusing on demographic-socio-economic characteristics, morbidity status, healthcare utilization, and expenditure...
2024: F1000Research
https://read.qxmd.com/read/38571894/differentiation-of-invasive-ductal-and-lobular-carcinoma-of-the-breast-using-mri-radiomic-features-a-pilot-study
#2
JOURNAL ARTICLE
Sudeepta Maiti, Shailesh Nayak, Karthikeya D Hebbar, Saikiran Pendem
BACKGROUND: Breast cancer (BC) is one of the main causes of cancer-related mortality among women. For clinical management to help patients survive longer and spend less time on treatment, early and precise cancer identification and differentiation of breast lesions are crucial. To investigate the accuracy of radiomic features (RF) extracted from dynamic contrast-enhanced Magnetic Resonance Imaging (DCE MRI) for differentiating invasive ductal carcinoma (IDC) from invasive lobular carcinoma (ILC)...
2024: F1000Research
https://read.qxmd.com/read/38523668/effectiveness-of-multi-component-modular-intervention-on-screen-based-and-non-screen-based-sedentary-time-among-adolescents-in-an-urban-area-of-mangalore-a-school-based-cluster-randomised-controlled-trial-protocol
#3
JOURNAL ARTICLE
Soundarya Janani S, Nithin Kumar, Mithun Rao, Rekha T, Prasanna Mithra, Bhaskaran Unnikrishnan, Ramesh Holla, Saraswathy M Vikraman, Himani Kotian
BACKGROUND: Behavioural risk factors may often present during adolescence and account for 70% of premature deaths during adulthood. Excessive sedentary behaviour and screen time have become significant concerns, especially among adolescents, due to their potential negative impact on physical and mental health. Adolescents with a high screen-based sedentary time are more likely to be physically inactive, have unhealthy body structure and poor academic performance. The objective of our study is to assess the effect of multi-component modular educational intervention on screen-based sedentary time (SST) and non-screen-based Sedentary time (NSST) among adolescents...
2024: F1000Research
https://read.qxmd.com/read/38495219/pelvic-pain-symptoms-and-endometriosis-characteristics-in-relation-to-oxidative-stress-among-adolescents-and-adults-with-and-without-surgically-confirmed-endometriosis
#4
JOURNAL ARTICLE
Amy L Shafrir, Britani Wallace, Ashley Laliberte, Allison F Vitonis, Christine B Sieberg, Kathryn L Terry, Stacey A Missmer
Background: While the majority of reproductive-aged females will experience pelvic pain during their lives, biological mechanisms underlying pelvic pain are not well understood. We investigated associations between pelvic pain symptoms and oxidative stress among people with and without surgically-confirmed endometriosis. Methods: Using an enzyme-linked immunosorbent assay, we measured 8-Hydroxy-2'-deoxyguanosine (8-OHdG) in urine samples and corrected for creatinine levels in 434 surgically-confirmed endometriosis participants compared to 605 participants never diagnosed with endometriosis...
2024: F1000Research
https://read.qxmd.com/read/38456172/salutogenesis-a-sense-of-coherence-and-health-among-british-military-veterans-exposed-to-impactful-life-challenges-the-emergence-of-post-traumatic-growth-and-positive-deviance-within-a-%C3%A2-life-story-approach
#5
JOURNAL ARTICLE
Richard Mottershead, Muhammad Arsyad Subu, Nabeel Al-Yateem, Wegdan Bani-Issa, Fatma Refaat Ahmed, Mini Sara Abraham, Jacqueline Maria Dias, Mustafa Muhamad Habeb, Nafi Alonaizi
BACKGROUND: This study sought to capture the perspectives and experiences of two sub-groups of military veterans, namely those who had previously been identified as offenders and those employed as practitioners within the criminal justice system in the United Kingdom. METHODS: The lead author undertook narrative inquiry in the form of life story research. The life stories of 17 in-depth interviews were conducted across England and Wales, allowing for insight into the lived experiences of two life story trajectories of the health of military veterans...
2024: F1000Research
https://read.qxmd.com/read/38450050/hospital-based-interventional-two-arm-parallel-comparative-study-on-dydrogesterone-vs-combined-oral-contraceptive-pills-for-functional-ovarian-cysts
#6
RANDOMIZED CONTROLLED TRIAL
Muneeba Shaikh, Neema Acharya
BACKGROUND: Functional ovarian cysts are common among women of reproductive age, often necessitating medical intervention. This hospital-based interventional study compares the efficacy and safety of combined oral contraceptive pills (COC) and dydrogesterone in managing functional ovarian cysts. METHODS: This randomized controlled trial will be conducted over two years at the Department of Obstetrics & Gynecology, AVBRH, Datta Meghe Institute of Medical Sciences...
2024: F1000Research
https://read.qxmd.com/read/38655208/evaluating-community-wide-temporal-sampling-in-passive-acoustic-monitoring-a-comprehensive-study-of-avian-vocal-patterns-in-subtropical-montane-forests
#7
JOURNAL ARTICLE
Shih-Hung Wu, Jerome Chie-Jen Ko, Ruey-Shing Lin, Chia-Hao Chang-Yang, Hsueh-Wen Chang
BACKGROUND: From passive acoustic monitoring (PAM) recordings, the vocal activity rate (VAR), vocalizations per unit of time, can be calculated and is essential for assessing bird population abundance. However, VAR is subject to influences from a range of factors, including species and environmental conditions. Identifying the optimal sampling design to obtain representative acoustic data for VAR estimation is crucial for research objectives. PAM commonly uses temporal sampling strategies to decrease the volume of recordings and the resources needed for audio data management...
2023: F1000Research
https://read.qxmd.com/read/38655207/validation-of-the-dominican-system-for-measuring-early-childhood-development
#8
JOURNAL ARTICLE
Laura V Sánchez-Vincitore, María Angélica Alonso Pellerano, María Elena Valdez, Angie Sabrina Jiménez, Carlos B Ruiz-Matuk, Arachu Castro, Felipe Díaz, Daniel Cubilla-Bonnetier
BACKGROUND: The purpose of the study was to determine the psychometric properties of the Dominican System for Measuring Early Childhood Development (SIMEDID, for its Spanish acronym), to adjust the sequence of item presentation, and to provide age-standardized norms for each item, to enable policy and program managers to make decisions based on specific and structured data. METHODS: After approval from an ethics committee, a total of 948 children from 0 to 60 months participated in this study...
2023: F1000Research
https://read.qxmd.com/read/38644927/role-of-apoptotic-inhibitors-viability-and-differentiation-in-low-oxygen-tension-of-mesenchymal-stem-cells-cultured-in-a-rat-model-of-ovarian-failure
#9
JOURNAL ARTICLE
Erma Safitri, Hery Purnobasuki, Muhammad Thohawi Elziyad Purnama, Shekhar Chhetri
Background: Stem cell therapy shows applications potential for malnutrition-induced ovarian failure in rat models. However, it is ineffective because of the lack of viability and differentiation of transplanted stem cells, resulting in low adaptation and survival rates. We aimed to determine whether stem cells cultured under low oxygen (O 2 ) tension improves the adaptability and viability of stem cells, as well as ovarian failure. Methods : After four days of culturing mesenchymal stem cells (MSCs) in 21% oxygen (normoxia) as the T2 group and 1% oxygen (low O 2 or hypoxia) as the T1 group, 200 million bone marrow-derived MSCs per rat were transplanted into female rats with ovarian failure (15 rats per treatment group)...
2023: F1000Research
https://read.qxmd.com/read/38644926/agroecosystem-exploration-for-antimicrobial-resistance-in-ahmedabad-india-a-study-protocol
#10
JOURNAL ARTICLE
Pachillu Kalpana, Timo Falkenberg, Sandul Yasobant, Deepak Saxena, Christiane Schreiber
INTRODUCTION: Antimicrobial resistance (AMR) has emerged as one of the leading threats to public health. AMR possesses a multidimensional challenge that has social, economic, and environmental dimensions that encompass the food production system, influencing human and animal health. The One Health approach highlights the inextricable linkage and interdependence between the health of people, animal, agriculture, and the environment. Antibiotic use in any of these areas can potentially impact the health of others...
2023: F1000Research
https://read.qxmd.com/read/38638178/a-guide-to-selecting-high-performing-antibodies-for-rna-binding-protein-tia1-for-use-in-western-blot-immunoprecipitation-and-immunofluorescence
#11
JOURNAL ARTICLE
Maryam Fotouhi, Donovan Worrall, Riham Ayoubi, Kathleen Southern, Peter S McPherson, Carl Laflamme
A member of the RNA-binding protein family, T-cell intracellular antigen-1 (TIA1) regulates mRNA translation and splicing as well as cellular stress by promoting stress granule formation. Variants of the TIA1 gene have implications in neurogenerative disorders including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Reproducible research on TIA1 would be enhanced with the availability of high-quality anti-TIA1 antibodies. In this study, we characterized twelve TIA1 commercial antibodies for Western Blot, immunoprecipitation, and immunofluorescence using a standardized experimental protocol based on comparing read-outs in knockout cell lines and isogenic parental controls...
2023: F1000Research
https://read.qxmd.com/read/38628976/translational-regulation-of-cell-invasion-through-extracellular-matrix-an-emerging-role-for-ribosomes
#12
REVIEW
David R Sherwood, Isabel W Kenny-Ganzert, Siddharthan Balachandar Thendral
Many developmental and physiological processes require cells to invade and migrate through extracellular matrix barriers. This specialized cellular behavior is also misregulated in many diseases, such as immune disorders and cancer. Cell invasive activity is driven by pro-invasive transcriptional networks that activate the expression of genes encoding numerous different proteins that expand and regulate the cytoskeleton, endomembrane system, cell adhesion, signaling pathways, and metabolic networks. While detailed mechanistic studies have uncovered crucial insights into pro-invasive transcriptional networks and the distinct cell biological attributes of invasive cells, less is known about how invasive cells modulate mRNA translation to meet the robust, dynamic, and unique protein production needs of cell invasion...
2023: F1000Research
https://read.qxmd.com/read/38628975/the-importance-of-teaching-climate-health-literacy-in-psychotherapeutic-training-and-continuing-education
#13
JOURNAL ARTICLE
Paolo Raile
Climate-health literacy is the ability to find, access, understand, interpret, evaluate, and communicate information about the impact of climate change on human health and to make decisions and act accordingly to that information. Climate change affects people's health in numerous ways, both directly and indirectly, e.g., by increasing the risks of cardiovascular disease, infections, depression, anxiety disorders, and trauma. It is important for health professionals to understand the complex interaction between climate change and health...
2023: F1000Research
https://read.qxmd.com/read/38623379/clinical-and-seasonal-pattern-of-dengue-in-a-tertiary-care-hospital-of-south-west-india
#14
JOURNAL ARTICLE
Darshan Bb, Ramesh Holla, Bhaskaran Unnikrishnan, Basavaprabhu Achappa, Robin Poovattil, Ashir Sharma, Shawna Simmy, Suryansh Prateek
BACKGROUND: Dengue is an emerging global viral disease with an increase 30-fold in incidence in the past fifty years. In the past decade it was restricted to only few a states of South and Northern India but in the recent past it has affected almost all the states in India. The objective of this study was to assess the clinical profile, trends and outcome of dengue cases. METHODS: This retrospective record based cross-sectional study was conducted in tertiary hospital, Mangaluru in Southern India...
2023: F1000Research
https://read.qxmd.com/read/38618023/general-versus-spinal-anesthesia-in-percutaneous-nephrolithotomy-a-systematic-review-and-meta-analysis
#15
Rinaldo Indra Rachman, Ponco Birowo, Ghifari Nurullah, Prof Sung Yong Cho, Widi Atmoko, Indah Suci Widyahening, Nur Rasyid
Background : Percutaneous nephrolithotomy (PCNL) is the preferred treatment for the removal of large kidney stones, sized >20 mm. However, there is still an ongoing debate concerning the best anesthesia for PCNL. This study aimed to compare the efficacy and safety between general and spinal anesthesia for PCNL. Methods : A systematic review and meta-analysis study. A systematic, electronic literature search was performed in several databases, including PubMed, Scopus, and Google Scholar until July 1 st , 2022...
2023: F1000Research
https://read.qxmd.com/read/38618022/corneal-blindness-in-the-developing-world-the-role-of-prevention-strategies
#16
JOURNAL ARTICLE
Anahita Kate, Sayan Basu
Corneal blindness is an important contributor to the burden of global blindness and has a greater prevalence in low-income countries of the developing world where resources and infrastructure are limited. The causes of corneal blindness too are different from high-income countries and include infectious keratitis, ocular trauma, and xerophthalmia. Persons with these indications tend to have unfavourable outcomes after corneal transplantation, limiting their chances of benefitting from this sight-saving procedure...
2023: F1000Research
https://read.qxmd.com/read/38618021/fixed-dose-combination-of-low-dose-pregabalin-and-duloxetine-or-pregabalin-monotherapy-for-neuropathic-pain-a-double-blind-randomized-parallel-group-study
#17
JOURNAL ARTICLE
Krishnaprasad K, Sunil Dutt, Pankaj Rattan, Ankit Dadhania, Ram Gupta, Deepa Joshi, Ashutosh Kakkad, Altaf Makwana, Pankaj Jha
Background: Treatment of neuropathic pain is challenging. Pregabalin and duloxetine are used as first-line therapy. Various international guidelines recommend a combination of first-line agents for the management of neuropathic pain. The objective of this study was to evaluate the efficacy and safety of a fixed-dose combination (FDC) of low-dose pregabalin and duloxetine compared to pregabalin monotherapy at week 7 in patients with moderate to severe neuropathic pain. Methods: This was a phase 3, randomized, double-blind, double-dummy parallel-group non-inferiority study conducted at 17 sites across India...
2023: F1000Research
https://read.qxmd.com/read/38618020/the-first-released-available-genome-of-the-common-ice-plant-mesembryanthemum-crystallinum-l-extended-the-research-region-on-salt-tolerance-c-3-cam-photosynthetic-conversion-and-halophilism
#18
JOURNAL ARTICLE
Ryoma Sato, Yuri Kondo, Sakae Agarie
Background: The common ice plant ( Mesembryanthemum crystallinum L.) is an annual herb belonging to the genus Mesembryanthemum of the family Aizoaceae, native to Southern Africa. Methods: We performed shotgun genome paired-end sequencing using the Illumina platform to determine the genome sequence of the ice plants. We assembled the whole genome sequences using the genome assembler "ALGA" and "Redundans", then released them as available genomic information. Finally, we mainly estimated the potential genomic function by the homology search method...
2023: F1000Research
https://read.qxmd.com/read/38618019/university-students-dataset-related-to-achievement-classroom-practices-perceptions-and-attitudes-of-multimedia-based-learning-quantum-physics
#19
JOURNAL ARTICLE
Pascasie Nyirahabimana, Evariste Minani, Mathias Nduwingoma, Imelda Kimeza
This dataset presents data collected to assess teaching and learning of quantum physics at the University of Rwanda - College of Education (UR-CE), Rwanda. Data were collected between August and November 2019 as the baseline, and between January and April 2022 under a quasi-experimental design. Three sets of data were collected. The first set was about students' performance and conceptual understanding collected before and after teaching intervention (lecture method or multimedia-aided approach) using mainly Quantum Physics Conceptual Survey (QPCS)...
2023: F1000Research
https://read.qxmd.com/read/38618018/indoor-environmental-quality-in-schools-notech-solution-vs-standard-solution
#20
JOURNAL ARTICLE
Carlo Volf, Klaus Martiny, Mathias Andersen, Bodil Engberg Pallesen
BACKGROUND: In many Danish schools, the indoor environmental quality (IEQ) is challenged and studies document a poor IEQ in a majority of existing schools. Municipalities cannot afford comprehensive renovations and expensive mechanical ventilation solutions, hence public schools often suffer from poor indoor environment conditions. This study tests a new façade based, demand-controlled ventilation solution called NOTECH in the renovation of school. The study tests NOTECH vs. existing mechanical ventilation solution, comparing performance of both solutions at Skovbrynet Skole in Denmark...
2023: F1000Research
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