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European Heart Journal. Acute Cardiovascular Care

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https://read.qxmd.com/read/30759994/early-intravenous-beta-blockers-in-patients-undergoing-primary-percutaneous-coronary-intervention-for-st-segment-elevation-myocardial-infarction-a-patient-pooled-meta-analysis-of-randomized-clinical-trials
#1
Niels Pg Hoedemaker, Vincent Roolvink, Robbert J de Winter, Niels van Royen, Valentin Fuster, José M García-Ruiz, Fikret Er, Natig Gassanov, Kenji Hanada, Ken Okumura, Borja Ibáñez, Arnoud W van 't Hof, Peter Damman
BACKGROUND: Conflicting evidence is available on the efficacy and safety of early intravenous beta-blockers before primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. We performed a patient-pooled meta-analysis of trials comparing early intravenous beta-blockers with placebo or routine care in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention. AIM: The aim of this study was to evaluate the clinical and safety outcomes of intravenous beta-blockers in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention...
February 14, 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30714389/beta-blockers-for-post-acute-coronary-syndrome-mid-range-ejection-fraction-a-nationwide-retrospective-study
#2
Fernando Montenegro Sá, Rita Carvalho, Catarina Ruivo, Luís Graça Santos, Alexandre Antunes, Francisco Soares, Adriana Belo, João Morais
BACKGROUND: Patients with mid-range ejection fraction (40-49%) are in focus due to the newly defined entity of heart failure with mid-range ejection fraction. Acute coronary syndromes are a major aetiology for heart failure with mid-range ejection fraction. We aim to evaluate which therapeutic decisions are associated with inhospital survival benefit in post-acute coronary syndrome patients categorised according to the ejection fraction. METHODS AND RESULTS: The authors analysed a cohort of a multicentre national registry enrolling acute coronary syndrome patients between 2010 and 2016, classified according to their ejection fraction before hospital discharge...
February 4, 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30706721/acute-diagonal-induced-st-elevation-myocardial-infarction-and-electrocardiogram-guidance-in-the-era-of-primary-coronary-intervention-new-insights-into-an-old-tool
#3
Rami Abu Fanne, Michael Kleiner Shochat, Avraham Shotan, Aharon Frimerman, Emad Maraga, Naama Amsalem, Yaniv Levi, Simcha R Meisel
BACKGROUND: Previous studies, published before the advent of primary reperfusion, described the electrocardiographic features of ST-segment elevation myocardial infarction (STEMI) caused by total diagonal artery occlusion, as demonstrated at pre-discharge coronary angiography. We aimed to assess the electrocardiographic and echocardiographic features in STEMI unequivocally attributed to a diagonal lesion in the era of primary coronary intervention. METHODS: The electrocardiograms and echocardiograms of patients sustaining STEMI caused by diagonal artery involvement were compared with those of patients with STEMI attributed to proximal or mid left anterior descending artery (LAD) lesions...
February 1, 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30667275/hyponatremia-at-discharge-is-associated-with-adverse-prognosis-in-acute-heart-failure-syndromes-with-preserved-ejection-fraction-a-report-from-the-jasper-registry
#4
Yu Sato, Akiomi Yoshihisa, Masayoshi Oikawa, Toshiyuki Nagai, Tsutomu Yoshikawa, Yoshihiko Saito, Kazuhiro Yamamoto, Yasuchika Takeishi, Toshihisa Anzai
INTRODUCTION: Hyponatremia predicts adverse prognosis in patients with heart failure in particular with reduced ejection fraction. In contrast, it has recently been reported that hyponatremia on admission is not a predictor of post-discharge mortality in patients with heart failure with preserved ejection fraction. We investigated the prognostic impact of hyponatremia at discharge in patients with heart failure with preserved ejection fraction and its clinical characteristics. METHODS AND RESULTS: The Japanese Heart Failure Syndrome with Preserved Ejection Fraction (JASPER) registry is a nationwide, observational, prospective registration of consecutive Japanese patients hospitalised with heart failure with preserved ejection fraction and left ventricular ejection fraction of 50% or greater...
January 22, 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30663317/temporal-trends-in-management-and-outcomes-of-patients-with-acute-coronary-syndrome-according-to-body-mass-index
#5
Zach Rozenbaum, Eyal Klein, Tal Cohen, Nir Shlomo, David Pereg, Mony Shuvy
BACKGROUND: Obesity is a major public health concern. We sought to investigate temporal trends in characteristics and outcomes of acute coronary syndrome patients according to body mass index. METHODS: The study population consisted of patients who were included in the Acute Coronary Syndromes Israeli Surveys during 2000-2016. Patients were categorised into three groups according to body mass index: below 25 kg/m2 , 25-30 kg/m2 (overweight) and above 30 kg/m2 (obese)...
January 21, 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30652942/the-prognostic-impact-of-the-uric-acid-level-in-patients-who-require-cardiovascular-intensive-care-is-serum-uric-acid-a-surrogate-biomarker-for-critical-patients-in-the-non-surgical-intensive-care-unit
#6
Yusaku Shibata, Akihiro Shirakabe, Hirotake Okazaki, Masato Matsushita, Tomofumi Sawatani, Saori Uchiyama, Kenichi Tani, Nobuaki Kobayashi, Toshiaki Otsuka, Noritake Hata, Kuniya Asai, Wataru Shimizu
BACKGROUND: The prognostic impact of hyperuricemia and the factors that induce hyperuricemia in cardiovascular intensive care patients remain unclear. METHODS AND RESULTS: A total of 3257 emergency department patients were screened, and data for 2435 patients who were admitted to an intensive care unit were analyzed. The serum uric acid level was measured within 15 min of admission. The patients were assigned to a low-uric acid group (uric acid ⩽7.0 mg/dl, n=1595) or a high-uric acid group (uric acid >7...
January 17, 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30632777/survival-of-patients-with-and-without-diabetes-following-out-of-hospital-cardiac-arrest-a-nationwide-danish-study
#7
Grímur Høgnason Mohr, Kathrine B Søndergaard, Jannik L Pallisgaard, Sidsel Gamborg Møller, Mads Wissenberg, Lena Karlsson, Steen Møller Hansen, Kristian Kragholm, Lars Køber, Freddy Lippert, Fredrik Folke, Tina Vilsbøll, Christian Torp-Pedersen, Gunnar Gislason, Shahzleen Rajan
BACKGROUND: Research regarding out-of-hospital cardiac arrest (OHCA) survival of diabetes patients is sparse and it remains unknown whether initiatives to increase OHCA survival benefit diabetes and non-diabetes patients equally. We therefore examined overall and temporal survival in diabetes and non-diabetes patients following OHCA. METHODS: Adult presumed cardiac-caused OHCAs were identified from the Danish Cardiac Arrest Registry (2001-2014). Associations between diabetes and return of spontaneous circulation upon hospital arrival and 30-day survival were estimated with logistic regression adjusted for patient- and OHCA-related characteristics...
January 11, 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30632764/electrocardiography-changes-and-their-significance-during-treatment-of-patients-with-intermediate-high-and-high-risk-pulmonary-embolism
#8
Natasha Novicic, Boris Dzudovic, Bojana Subotic, Sonja Shalinger-Martinovic, Slobodan Obradovic
BACKGROUND: Electrocardiography (ECG) signs, typical or acute pulmonary embolism, and their changes can be used for the prediction of clinical and haemodynamic outcomes. PURPOSE: To study the predictive value of the resolution of admission ECG signs in higher risk pulmonary embolism patients for 30-day survival and for the decrease in right ventricular systolic pressure. METHODS: We analysed the 12-lead ECGs at admission and daily for the first 5 days after hospitalisation in 110 intermediate-high and high-risk pulmonary embolism patients admitted to the intensive care unit of a single tertiary centre...
January 11, 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30632383/release-of-mitochondrial-dna-is-associated-with-mortality-in-severe-acute-heart-failure
#9
Konstantin A Krychtiuk, Raphael Wurm, Sarah Ruhittel, Max Lenz, Kurt Huber, Johann Wojta, Gottfried Heinz, Martin Hülsmann, Walter S Speidl
BACKGROUND: Inflammation is regarded as an important trigger for disease progression in heart failure. Particularly in severe acute heart failure, tissue hypoxia may lead to cellular damage and the release of intracellular mitochondrial DNA, which acts as an activator of the immune system due to its resemblance to bacterial DNA. It may therefore serve as a mediator of disease progression. The aim of this study was to determine circulating levels of mitochondrial DNA and its association with mortality in patients with heart failure in different presentations...
January 11, 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30618277/serial-high-sensitivity-cardiac-troponin-t-measurements-to-rule-out-acute-myocardial-infarction-and-a-single-high-baseline-measurement-for-swift-rule-in-a-systematic-review-and-meta-analysis
#10
M Arslan, A Dedic, E Boersma, E A Dubois
AIMS: The purpose of this study was to determine (a) the ability of serial high-sensitivity cardiac troponin T measurements to rule out acute myocardial infarction and (b) the ability of a single high baseline high-sensitivity cardiac troponin T measurement to rule in acute myocardial infarction in patients presenting to the emergency department with acute chest pain. METHODS AND RESULTS: Embase, Medline, Cochrane, Web of Science and Google scholar were searched for prospective cohort studies that evaluated parameters of diagnostic accuracy of serial high-sensitivity cardiac troponin T to rule out acute myocardial infarction and a single baseline high-sensitivity cardiac troponin T value>50 ng/l to rule in acute myocardial infarction...
January 8, 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30618264/incidence-and-outcome-of-peri-procedural-cardiogenic-shock-results-from-the-international-euro-heart-survey-pci-registry
#11
Kay F Weipert, Timm Bauer, Holger M Nef, Matthias Hochadel, Franz Weidinger, Anselm K Gitt, Uwe Zeymer, Christian W Hamm
BACKGROUND: There is a large body of literature on acute myocardial infarction complicated by cardiogenic shock. However, very little is known about patients who are initially haemodynamically stable and develop cardiogenic shock during percutaneous coronary intervention. METHODS: A total of 47,407 consecutive patients were prospectively enrolled in the PCI Registry of the Euro Heart Survey Programme. We analysed interventions with peri-procedural complications that were classified as 'shock induced by procedure' on the case report form...
January 8, 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30569736/targeting-elevated-left-ventricular-end-diastolic-pressure-following-primary-percutaneous-coronary-intervention-for-st-segment-elevation-myocardial-infarction-a-phase-one-safety-and-feasibility-study
#12
Arshad A Khan, Allan J Davies, Nicholas J Whitehead, Michael McGee, Mohammed S Al-Omary, David Baker, Rohan Bhagwandeen, Ian Renner, Tazeen Majeed, Rachael Hatton, Nicholas J Collins, John Attia, Andrew J Boyle
INTRODUCTION: Elevated left ventricular end diastolic pressure (LVEDP) is an independent predictor of mortality and heart failure in patients with ST-segment elevation myocardial infarction (STEMI). Whether lowering elevated LVEDP improves outcomes remains unknown. METHODS: This non-randomized, single blinded study with prospective enrolment and sequential group allocation recruited patients undergoing primary percutaneous coronary intervention for STEMI with LVEDP ⩾ 20 mmHg measured immediately after primary percutaneous coronary intervention...
December 20, 2018: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30543118/time-is-up-for-treatment-inequity-in-women-with-acute-coronary-syndromes
#13
Angela H E M Maas
No abstract text is available yet for this article.
December 13, 2018: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30525871/the-role-of-perioperative-cardiorespiratory-support-in-post-infarction-ventricular-septal-rupture-related-cardiogenic-shock
#14
Albert Ariza-Solé, José C Sánchez-Salado, Fabrizio Sbraga, Daniel Ortiz, José González-Costello, Arnau Blasco-Lucas, Oriol Alegre, David Toral, Victòria Lorente, Eva Santafosta, Jacobo Toscano, Andrea Izquierdo, Albert Miralles, Ángel Cequier
BACKGROUND: Current guidelines recommend emergency surgical correction in patients with post infarction ventricular septal rupture (PIVSR), but patients with multiorgan failure are commonly managed conservatively because of high surgical risk. We assessed characteristics and outcomes of operated PIVSR patients with or without the use of short-term ventricular assist devices (ST-VADs). We also assessed the impact of a ST-VAD on the performance of surgery. METHODS: We retrospectively analysed all consecutive patients with PIVSR between January 2004 and May 2017...
December 10, 2018: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30516390/multisite-vascular-disease-in-acute-coronary-syndromes-increased-in-hospital-mortality-and-no-improvement-over-time
#15
Marco Roffi, Dragana Radovanovic, Juan F Iglesias, Franz R Eberli, Philip Urban, Giovanni B Pedrazzini, Paul Erne, Hans Rickli
INTRODUCTION: Limited data are available on the impact of multisite artery disease in patients with acute coronary syndromes. In particular, it is unknown whether the outcomes of those high-risk patients have improved over time. Therefore, we addressed the multisite artery disease patient population enrolled in the Swiss nationwide prospective acute coronary syndromes cohort study AMIS Plus over two decades. METHODS: All patients enrolled from January 1999 to October 2016 were stratified according to the presence of isolated coronary artery disease or multisite artery disease, defined as coronary artery disease with known concomitant vascular disease (i...
December 5, 2018: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30477317/prognostic-significance-of-emergency-department-bypass-in-stable-and-unstable-patients-with-st-segment-elevation-myocardial-infarction
#16
Karl Heinrich Scholz, Tim Friede, Thomas Meyer, Claudius Jacobshagen, Björn Lengenfelder, Jens Jung, Claus Fleischmann, Hiller Moehlis, Hans G Olbrich, Rainer Ott, Albrecht Elsässer, Stephen Schröder, Christian Thilo, Werner Raut, Andreas Franke, Lars S Maier, Sebastian Kg Maier
BACKGROUND: In ST-segment elevation myocardial infarction (STEMI) patients treated with percutaneous coronary intervention, direct transport from the scene to the catheterisation laboratory bypassing the emergency department has been shown to shorten times to reperfusion. The aim of this study was to investigate the effects of emergency department bypass on mortality in both haemodynamically stable and unstable STEMI patients. METHODS: The analysis is based on a large cohort of STEMI patients prospectively included in the German multicentre Feedback Intervention and Treatment Times in ST-Elevation Myocardial Infarction (FITT-STEMI) trial...
November 27, 2018: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30468395/pre-hospital-risk-assessment-in-suspected-non-st-elevation-acute-coronary-syndrome-a-prospective-observational-study
#17
Dominique N van Dongen, Rudolf T Tolsma, Marion J Fokkert, Erik A Badings, Aize van der Sluis, Robbert J Slingerland, Arnoud Wj van 't Hof, Jan Paul Ottervanger
BACKGROUND: Pre-hospital risk stratification of non-ST-elevation acute coronary syndrome (NSTE-ACS) by the complete HEART score has not yet been assessed. We investigated whether pre-hospital risk stratification of patients with suspected NSTE-ACS using the HEART score is accurate in predicting major adverse cardiac events (MACE). METHODS: This is a prospective observational study, including 700 patients with suspected NSTE-ACS. Risk stratification was performed by ambulance paramedics, using the HEART score; low risk was defined as HEART score ⩽ 3...
November 23, 2018: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30741009/medical-misinformation-vet-the-message
#18
Joseph A Hill
No abstract text is available yet for this article.
February 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30741008/focus-on-st-elevation-myocardial-infarction
#19
(no author information available yet)
No abstract text is available yet for this article.
February 2019: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/30480482/renal-dysfunction-and-cardiogenic-shock-complicating-acute-coronary-syndromes
#20
(no author information available yet)
No abstract text is available yet for this article.
December 2018: European Heart Journal. Acute Cardiovascular Care
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