journal
https://read.qxmd.com/read/33457321/can-we-turn-off-the-covid-biting-tail-inflammation
#21
JOURNAL ARTICLE
V Giudice, A Filippelli, C Selleri
No abstract text is available yet for this article.
December 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/33457320/head-and-neck-surgery-residency-during-covid-19-pandemic-lessons-from-southern-italy
#22
JOURNAL ARTICLE
P De Luca
No abstract text is available yet for this article.
December 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/33457319/histopathology-of-celiac-disease-position-statements-of-the-italian-group-of-gastrointestinal-pathologists-gipad-siapec
#23
JOURNAL ARTICLE
V Villanacci, C Ciacci, T Salviato, G Leoncini, L Reggiani Bonetti, T Ragazzini, F Limarzi, L Saragoni
Celiac Disease (CeD) is an immune-mediated inflammatory disorder of the small intestine, affecting genetically susceptible individuals when exposed to gluten. Small intestinal biopsy interpretation has been the "gold standard" for celiac disease (CeD) for over 50 years. Despite today's availability of sensitive and specific serological tests, the histopathological features from mucosal biopsy play a key role in diagnosing when CeD is suspected. Such a diagnostic approach requires a multidisciplinary team to optimize both tissue sampling and interpretation via the interaction between the pathologist and the gastroenterologist...
December 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/33457318/assessing-the-impact-of-a-community-based-pro-active-monitoring-program-addressing-the-need-for-care-of-community-dwelling-citizens-aged-more-than-80-protocol-for-a-prospective-pragmatic-trial-and-results-of-the-baseline-assessment
#24
JOURNAL ARTICLE
G Liotta, O Madaro, P Scarcella, M C Inzerilli, B Frattini, F Riccardi, N Accarino, S Mancinelli, E Terracciano, S Orlando, M C Marazzi
The aim of this paper is to describe the protocol of a study assessing the impact of a Community-based pro-Active Monitoring Program, by measuring the effect in counteracting the adverse outcomes related to frailty. Methods: a prospective pragmatic trial will be carried out to describe the impact of an intervention on people aged>80, adjusted for relevant parameters: demographic variables, comorbidities, disability and bio-psycho-social frailty. They have been assessed with the Functional Geriatric Evaluation questionnaire that is a validated tool...
December 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/33457317/saving-limited-resources-during-covid-19-pandemic
#25
JOURNAL ARTICLE
O Piazza
No abstract text is available yet for this article.
December 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/33457316/decluttering
#26
JOURNAL ARTICLE
C Ciacci, O Piazza
No abstract text is available yet for this article.
December 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/33457315/the-many-faces-of-covid-19-organizing-pneumonia-op-pattern-hrct-features
#27
JOURNAL ARTICLE
G Rea, Tullio Valente, R Lieto, G Bocchini, E Marchiori, A Pinto, A Maglio, A Vatrella
Covid-19 (coronavirus disease 2019) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). On 30 January 2020 the World Health Organization (WHO) declared that the outbreak of Covid-19 realizes a public health emergency of international concern. Because of the primary involvement of the respiratory system, chest CT is strongly recommended in suspected Covid-19 cases, for both initial and follow-up. We present the case of a Covid-19 patient, a 57-year-old man, with a typical HRCT course of OP reaction...
December 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/33457314/the-frailty-of-the-invincible
#28
JOURNAL ARTICLE
M Illario, V Zavagli, L Noronha Ferreira, M Sambati, A Teixeira, F Lanata, S Pais, J Farrell, D Tramontano
The COVID-19 pandemic has unveiled the frailty of our societies from too many points of view to look away. We need to understand why we were all caught unprepared. On the one hand, we have all short memories. As we forget too quickly, we were unable to recognize key factors influencing response and preparedness to public health threats. For many years, economic evaluation pushed governments all over the world to cut resources for public health systems, with COVID-19 pandemic the question arises: do we spend too much or too little on health care? What is the right amount to spend on health? Moreover, in many countries, the privatisation, or semi-privatisation, of healthcare may give rise to inequitable access to health care for everyone...
December 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/33457326/a-case-series-of-blastic-plasmacytoid-dendritic-cell-neoplasia
#29
JOURNAL ARTICLE
B Serio, V Giudice, M D'Addona, R Guariglia, M Gorrese, A Bertolini, F D'Alto, B Cuffa, D Pellegrino, M Langella, C Selleri
Blastic plasmacytoid dendritic cell neoplasm (BPDCN), an extremely rare and aggressive tumor, derives from plasmacytoid dendritic cell precursors and is characterized by CD4 and CD56 positivity accompanied by the expression of isolated myeloid, B- or T-cell lineage markers. Despite the recent introduction of specific targeted therapies, prognosis is still poor with a median overall survival of one year, and allogeneic bone marrow transplantation remains the only curative treatment in eligible patients. In this series, we described two cases of adult BPDCN treated with high dose cytarabine and methotrexate and autologous hematopoietic stem cell transplantation, or fludarabine, cytarabine, and idarubicin achieving the first a complete lasting remission, while the second only a transient improvement in skin lesions...
October 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/34447722/go-for-it-exercising-makes-you-happy-and-strong
#30
JOURNAL ARTICLE
M Illario, V De Luca, A Cano, D Tramontano
Despite it is generally recognized the beneficial role of physical activity, large portion of the population is physically inactive. Very alarmingly, the well-known gender gap in physical activity is constantly increasing. Several barriers obstacle women to perform physical activity although exercising would be of paramount importance for their health in particular during pregnancy and menopause. In addition to physical health benefits, physical activity may influence well-being and resilience, greatly impacting on quality of life...
September 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/34447721/pilot-study-on-the-effectiveness-of-reminiscence-therapy-on-cognition-depressive-symptoms-and-quality-of-life-in-nursing-home-residents
#31
JOURNAL ARTICLE
I Gil, P Santos-Costa, E Bobrowicz-Campos, A Barata, V Parola, A Coelho, E Santos, M L Almeida, J ApĆ³stolo
Aim: This study aimed to assess the effectiveness of the group Reminiscence Therapy (RT) on cognition, depressive symptoms, and quality of life (QOL) in older adults recruited in nursing homes. Methods: A pilot study with a one-group pretest-posttest design was conducted between September 2017 and March 2018 in five nursing homes from central Portugal. A comprehensive RT program (Core program followed by a Follow-up program) was provided to clinically stable volunteers aged 65 years or more, who did not have severe cognitive impairment...
September 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/34447720/the-management-of-asymptomatic-carotid-stenosis-is-there-a-benefit-to-operate-elderly-patients
#32
JOURNAL ARTICLE
N M Bouayed, A Sekkal
Background: We present a retrospective study of a series of 40 patients over the age of 75 operated for an asymptomatic carotid stenosis. The results were evaluated during an average of 3 years of follow-up. Material and method: The study is retrospective and monocentric. The series includes 40 patients aged over 75 years and with an average age of 78.5 years (range 75-82). Patients underwent surgery for an asymptomatic carotid stenosis of more than 80%. The technique in all case was a carotid endarterectomy...
September 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/34447719/good-practices-for-a-decade-for-active-and-healthy-ageing-little-drops-make-the-mighty-oceanlittle-things-julia-carney
#33
EDITORIAL
M Illario, G Tramontano, V De Luca, O Piazza
No abstract text is available yet for this article.
September 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/34447718/ionized-or-total-magnesium-levels-what-should-we-measure-in-critical-ill-patients
#34
JOURNAL ARTICLE
G Scarpati, D Baldassarre, F Oliva, G Pascale, O Piazza
Monitoring and measuring magnesium (Mg) values are essential to prevent the development of numerous complications in perioperative medicine and critically ill patients. Although previous studies suggest that measuring free ionized magnesium (iMg) is more useful for estimating Mg status, clinicians currently rely on measurement of total serum magnesium to determine if supplemental magnesium is needed. In this review, we analyzed the recent literature to decide whether it is better to measure ionized serum Mg or total serum Mg when assessing magnesium status, whether iMg predicts clinical outcome, and what are the difficulties in measuring serum iMg levels in intensive care patients and perioperative medicine...
September 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/34447717/kl-6-levels-in-covid-19
#35
JOURNAL ARTICLE
G Scarpati, B Polverino, M Boffardi, O Piazza
No abstract text is available yet for this article.
September 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/34447715/drug-induced-sleep-endoscopy-dise-with-simulation-bite-to-predict-the-success-of-oral-appliance-therapy-in-treating-obstructive-sleep-apnea-hypopnea-syndrome-osahs
#36
JOURNAL ARTICLE
Matteo Cavaliere, Pietro De Luca, Carla De Santis, Alfonso Scarpa, Massimo Ralli, Arianna Di Stadio, Pasquale Viola, Giuseppe Chiarella, Claudia Cassandro, Francesco Cassandro
STUDY OBJECTIVES: Oral appliances have gained their place in the treatment of obstructive sleep apnea (OSA) where custom-made titratable mandibular advancement devices (MAD) have become the oral appliance of choice. This study aimed to asses the value of the drug-induced sleep endoscopy (DISE) using a MAD in the prediction of treatment outcome for OSAHS. METHODS: This is a prospective, single-center cohort study that enrolled sixty-six consecutive patients with diagnosed OSA (5 events/h < apnea-hypopnea index (AHI) < 50 events/h) to be treated with a custom-made titratable MAD...
September 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/34447714/psychological-stress-and-cancer-new-evidence-of-an-increasingly-strong-link
#37
JOURNAL ARTICLE
M Abate, M Citro, M Caputo, S Pisanti, R Martinelli
To date stress, a highly complex process that disrupts homeostasis and involves environmental and psychosocial factors, is considered as one of the most crucial factor that affects our daily life, especially urban dweller's life. Clinical and experimental studies widely support the notion that adrenergic stimulation due to chronic stress affects inflammation and metabolism. In this work, supported by several recent scientific evidences, we show how stress plays a positive role in cancer initiation, progression and cancer metastasis, a negative role for anti-tumor immune function and therapy response...
September 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/34447713/pharmacological-surgical-and-diagnostic-innovations-in-meniere-s-disease-a-review
#38
JOURNAL ARTICLE
A Scarpa, M Ralli, E De Bonis, D Troisi, A Montanino, P Viola, G Chiarella, F M Gioacchini, M Cavaliere, E Cassandro, C Cassandro
Meniere's disease is an inner ear disorder characterized by the presence of endolymphatic hydrops in the inner ear and symptomatology of recurrent and debilitating vertigo attacks, tinnitus, aural fullness, and fluctuating sensorineural hearing loss. Although many therapeutic options for MD have been proposed during years, no consensus has been reached by the scientific community. In the last decade, many therapeutic options have been proposed, as intratympanic steroid, intratympanic gentamicin, and intravenous glycerol...
September 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/34447712/meningoencephalitis-associated-with-sars-coronavirus-2
#39
JOURNAL ARTICLE
G Iaconetta, P De Luca, A Scarpa, C Cassandro, E Cassandro
The aim of this work is to clarify the incidence of meningitis/encephalitis in SARS-CoV-2 patients. We conducted an initial search in PubMed using the Medical Subject Headings (MeSH) terms "meningitis," and "encephalitis,", and "COVID-19" to affirm the need for a review on the topic of the relationship between meningitis/encephalitis and SARS-CoV-2 infection. We included case series, case reports and review articles of COVID-19 patients with these neurological symptoms. Through PubMed database we identified 110 records...
September 2020: Translational Medicine @ UniSa
https://read.qxmd.com/read/34447711/can-we-turn-off-the-covid-biting-tail-inflammation
#40
JOURNAL ARTICLE
Giudice Valentina, Filippelli Amelia, Selleri Carmine
No abstract text is available yet for this article.
September 2020: Translational Medicine @ UniSa
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