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Journal of Reproduction & Infertility

Jara Ben-Nagi, Rabi Odia, Xavier Viñals Gonzalez, Carleen Heath, Dhruti Babariya, Sioban SenGupta, Paul Serhal, Dagan Wells
Background: The exact origin of cell-free DNA found in spent culture media or blastocoel fluid is currently unknown but with the potential to become an improved source of DNA for chromosomal analysis than trophectoderm biopsy samples, it provides a superior representation of the fetal genetic status. However, the genetic material contained within the blastocoel cavity may be more reliable to assessment of embryo euploidy in a clinical context than trophectoderm of cell-free DNA. Case Presentation: This is the first UK case report where all three sources of DNA were analyzed in a clinical setting on 29 th January 2018 at the Centre for Reproductive and Genetic Health, London, leading to an ongoing clinical pregnancy...
January 2019: Journal of Reproduction & Infertility
Tamima Al-Dughaishi, Mussab Mubarak Hamed Al-Jabri, Amjad Hamed Al-Haddabi, Vaidyanathan Gowri
Background: This study aimed to find out the patients preference towards the management of pregnancy loss to either Misoprostol or dilatation and evacuation or curettage (D&C) in two different study periods. Methods: Retrospective chart review study included a total of 411 patients. The first study period was January to December 2010 and the second study period was January to December 2014. All patients were managed in Sultan Qaboos University Hospital of Oman...
January 2019: Journal of Reproduction & Infertility
Desta Erkalo Abame, Muluembet Abera, Amanuel Tesfay, Yonas Yohannes, Dejene Ermias, Terefe Markos, Gelila Goba
Background: Unintended pregnancy has direct relation with poor utilization of maternal health care services and also associated with unhealthy behaviors during pregnancy. Few studies have examined the association between unintended pregnancy and maternal health behaviors during pregnancy in developing countries including Ethiopia. The purpose of the study was to determine the association of unintended pregnancy with use of antenatal care during pregnancy among pregnant women in Hadiya zone, southern Ethiopia...
January 2019: Journal of Reproduction & Infertility
Marzieh Mehrafza, Roya Kabodmehri, Zahra Nikpouri, Gholamreza Pourseify, Azadeh Raoufi, Azadeh Eftekhari, Sajedeh Samadnia, Ahmad Hosseini
Background: Despite the advancements in assisted reproductive technologies, repeated implantation failure (RIF) still remains a challenging problem for patients and clinicians. The aim of the present study was to compare the impact of intrauterine infusion of autologous platelet-rich plasma (PRP) and systemic administration of granulocyte colony stimulating factor (GCSF) on pregnancy outcome in patients with repeated implantation failure. Methods: The present retrospective cohort study included 123 patients with history of more than two repeated failed embryo transfers...
January 2019: Journal of Reproduction & Infertility
Megan Edwards Collins
Background: Infertility impacts approximately 16% of couples in the United States-roughly five million individuals. Experiencing infertility takes a physical and psychological toll on the infertile individual, as well as his/her partner. The goal of the current study was to explore and provide better insight into how infertility affects the roles and daily occupations (Such as self-care and work related tasks) of females. This information can better assist health care providers in providing quality care to such clients...
January 2019: Journal of Reproduction & Infertility
Seyed Mojtaba Ahmadi, Jamile Shahverdi, Mansour Rezaei, Mitra Bakhtiari, Kheirollah Sadeghi, Fateme Veisy, Maryam Shahverdi
Background: Infertility is a common disorder, exposing couples to complication such as the loss of mental health and the increase of marital conflicts. The aim of this study was to evaluate the effect of behavioral couple therapy on the enhancement of mental health and reduction of marital conflicts. Methods: In this clinical trial, 24 couples were selected using convenience sampling and were divided randomly into control (12 couples) and experimental (12 couples) groups...
January 2019: Journal of Reproduction & Infertility
Sepideh Sadeghi, Ali Reza Talebi, Abbas Shahedi, Mohammad Reza Moein, Abolghasem Abbasi-Sarcheshmeh
Background: Tamoxifen (TX) is widely used to treat idiopathic infertility in men. Using TX has been shown to produce sperm in patients with oligospermia and azoospermia and improve male fertility. The aim of this study was to evaluate the effects of TX on DNA and chromatin quality in mice regarding the importance of chromatin quality and sperm DNA at all stages of reproduction. Methods: 24 male NMRI mice were divided into 3 groups including dose 0.4 mg/kg/day that received basal diet and TX, dose 0...
January 2019: Journal of Reproduction & Infertility
Hamid Nazarian, Nahid Azad, Leila Nazari, Abbas Piryaei, Mohammad Hassan Heidari, Reza Masteri-Farahani, Maryam Karimi, Marefat Ghaffari-Novin
Background: Artificial oocyte activation (AOA) is a specialized method in assisted reproductive technique (ART). According to increasing concern about using AOA, it is necessary to evaluate sperm-borne oocyte activating factors (SOAFs) including phospholipase C zeta (PLCζ). In this study, PLCζ before AOA was evaluated first and then the impact of AOA on pre-implantation embryo development was investigated. Methods: This prospective clinical trial enrolled couples subjected to ICSI...
January 2019: Journal of Reproduction & Infertility
Shahla Chaichian
No abstract text is available yet for this article.
January 2019: Journal of Reproduction & Infertility
Effatf Merghati Khoei, Mansoureh Jamshidimanesh, Mohammad Hassan Emamian, Fatemeh Sheikhan, Kate Dolan, Kathleen T Brady
Background: Substance use disorders and risky sexual behavior coexist for some women. Explanatory models of women's sexuality in the context of substance use are under study. This study aimed to explore how women's sexual behavior can become risky in the context of substance use. Methods: In this ethnographic inquiry, 25 women with substance use disorders (SUDs) were included at two Drop-In-Centers (DICs) in South Tehran. Observation, semi-structured interviews and field notes were used to collect data...
October 2018: Journal of Reproduction & Infertility
Fatemeh Darabi, Mehdi Yaseri, Alireza Rohban, Farideh Khalajabadi-Farahani
Background: Lack of accurate menstrual knowledge, attitude, and practices leave female adolescents ignorant of the necessary health behaviors during menstruation. This study aimed to develop a menstrual health-seeking behavior questionnaire based on the theory of planned behavior to evaluate its psychometric properties in female adolescents in Tehran. Methods: This study was conducted on 578 female adolescents aged 12-15 years in Tehran. The first draft of the menstrual health-seeking behavior questionnaire containing 52 items was developed based on the theory of planned behavior (TPB)...
October 2018: Journal of Reproduction & Infertility
Tatiana Alekseevna Marakhovskaya, Elena Viktorovna Butenko, Konstantin Alekseevich Kovalenko, Elena Vladimirovna Mashkina
Background: The study was aimed to investigate the association of V EGFA gene polymorphic variants - 2578C>A (rs699947) and - 634G>C (rs2010963) and TGFB1 gene 915G>C (rs1800471) and gene expression level with miscarriage in the first trimester. Methods: 288 women with different courses of pregnancy and 61 chorionic tissue samples were involved in case-control study. Allele-specific polymerase chain reaction in real time was used for genotyping. Next, gene-gene interactions were analyzed using the multifactor dimensionality reduction method...
October 2018: Journal of Reproduction & Infertility
Roshanak Aboutorabi, Ehsan Behzadi, Mohammad Javad Sadegh, Seyed Pooriya Fatehi, Soroosh Semsarzadeh, Yasaman Zarrin, Mohammad Kazemi, Laleh Rafiee, Fatemeh Sadat Mostafavi
Background: According to the literature review, polymorphisms of tumor necrosis factor alpha's (TNF-α) promoter region are probably the genetic risk factors of recurrent pregnancy loss. This study has investigated five single nucleotide polymorphisms in the TNF-α gene's promoter region to evaluate their relationship with recurrent pregnancy loss disorder. Methods: Blood samples were taken from 65 women with recurrent pregnancy loss (Case group) and 65 healthy women with a history of successful pregnancy (Control group)...
October 2018: Journal of Reproduction & Infertility
Mahnaz Heidari, Sara Darbandi, Mahsa Darbani, Naser Amirjanati, Mahmood Bozorgmehr, Hojjat Zeraati, Mohammad Mehdi Akhondi, Mohammad Reza Sadeghi
Background: The selection of sperm with good genomic integrity and surface antigens is suggested for improving assisted reproductive technology (ART) outcome. The aim of this study was evaluating the heat shock protein (HSPA2), Dj-1 and serum amyloid P compound (SAP) three sperm surface proteomes as biomarkers for this purpose. Methods: In this study, semen samples were obtained from 114 men who presented at Avicenna Fertility Clinic for their treatment. The semen characteristics, DNA fragmentation Index (DFI), chromatin maturation index (CMI), biomarker levels, and their embryo quality were considered...
October 2018: Journal of Reproduction & Infertility
Maasoume Abdollahi, Mojdeh Salehnia, Saghar Salehpour, Shahram Pour-Beiranvand
Background: For improving the human ovarian tissue culture, this study was designed to assess the incidence of apoptosis in this tissue following vitrification and in vitro culture in the presence of leukemia inhibitory factor (LIF) as an anti-apoptotic factor. Methods: After collecting the ovarian tissue samples they were divided into non-vitrified and vitrified groups and cultured for 14 days in the presence and absence of LIF then morphological, ultrastructural and steroidogenesis studies, TUNEL and caspase-3/7 assays, and apoptosis analysis by real time RT-PCR were done in all groups...
October 2018: Journal of Reproduction & Infertility
Niloofar Agharezaee, Mehrdad Hashemi, Minoo Shahani, Kambiz Gilany
Precision medicine (PM) is an approach that has the power to create the best effect and safety of medicine and treatment with the least side effects for each person. PM is very helpful as sometimes due to inaccurate or late diagnosis or toxicities of the drugs irreversible side effect for patient's health are generated. This seemingly new and emerging science is also effective in preventing disease, due to differences in the genes, environment, and lifestyles of any particular person. PM can be a prominent criterion in infertility research...
October 2018: Journal of Reproduction & Infertility
Neda Nozari, Maryam Shafiei, Soheila Sarmadi
Background: Bowel endometriosis affects about 3.8-37% of women with endometriosis diagnosis. Most of the time endometriosis involves the recto-sigmoid. Right colon involvement is not common in endometriosis and also a few studies have reported obstructive endometriosis of bowel. Here, a case of endometriosis was reported with the ileocolic intussusception and cecal mass. Case Presentation: A 32y old woman was referred to Yas hospital due to severe low abdominal pain and vomiting...
October 2018: Journal of Reproduction & Infertility
Mohammad Reza Sadeghi
No abstract text is available yet for this article.
October 2018: Journal of Reproduction & Infertility
Enrique Perez de la Blanca, Maria Fuensanta Fernandez-Perez, Elena Del Mar Martin-Diaz, Manuel Lozano, Marta Garcia-Sanchez, Carolina Monedero
Background: Cryopreservation of oocytes is an efficient method of fertility preservation (FP) that can be applied in women suffering from gynecologic conditions that menace their reproductive future. Collection of oocytes becomes challenging in some scenarios, like the possibility of an ovarian cancer, the " ex-vivo " harvest of oocytes for FP, aspirating follicles directly from the ovarian specimen already excised by laparotomy or laparoscopy and it is an option for these cases...
July 2018: Journal of Reproduction & Infertility
Rosario Mendoza, Teresa Jáuregui, Maria Diaz-Nuñez, Mariana de la Sota, Alaitz Hidalgo, Marcos Ferrando, Lorea Martínez-Indart, Antonia Expósito, Roberto Matorras
Background: The number of multiple pregnancies has been significantly increased in the last decades due to assisted reproduction techniques development. Compared to singleton, twins and multiple pregnancies are associated to more complications and risks for both mother and children. The objective of this study was to examine the proportion of patients preferring a multiple birth over a singleton after an IVF/ICSI attempt, their reasons and the influence of socio-demographic and clinical parameters on their preference...
July 2018: Journal of Reproduction & Infertility
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