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Journals International Journal of Endoc...

International Journal of Endocrinology and Metabolism

https://read.qxmd.com/read/38665148/primary-hyperaldosteronism-in-a-normotensive-patient-a-case-report
#1
Amir Hossein Ghanooni, Mitra KazemiJahromi, Farhad Hosseinpanah
INTRODUCTION: Primary aldosteronism (PA) is a clinical syndrome characterized by hypertension, suppressed plasma renin activity (PRA), elevated plasma aldosterone concentration (PAC), and spontaneous hypokalemia. CASE PRESENTATION: We present a 37-year-old normotensive female with hypokalemia, high plasma aldosterone level, and suppressed renin. The patient was treated with eplerenone and potassium chloride supplement. Further investigation with a computed tomography (CT) scan revealed a mass in the left adrenal...
January 2024: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38665147/association-between-hdl2-c-and-hdl3-c-with-cardiovascular-disease-a-nested-case-control-study-in-an-iranian-population
#2
JOURNAL ARTICLE
Abdolreza Chary, Maryam Tohidi, Mitra Hasheminia, Melika Golmohammadi, Reza Haji Hosseini, Mehdi Hedayati, Fereidoun Azizi, Farzad Hadaegh
BACKGROUND: The contribution of high-density lipoprotein cholesterol (HDL-C) subclasses to incident cardiovascular disease (CVD) and coronary heart disease (CHD) remains a subject of debate. OBJECTIVES: The objective of this study was to investigate these associations in a population with a high prevalence of dyslipidemia and CVD. METHODS: In a nested case-control study, HDL-C and its subclasses (HDL2-C and HDL3-C) in 370 age and gender-matched case and control subjects were determined...
January 2024: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38694238/diabetic-ketoacidosis-after-covid-19-vaccine-in-patients-with-type-1-diabetes-mellitus
#3
JOURNAL ARTICLE
Fahad Bedaiwi Albedaiwi, Manar Alshammari, Metab Algeffari, Abdulmajeed Alfouzan, Yasmeen Alfouzan, Hassan Siddiq, Omaima Hussein
BACKGROUND: The coronavirus disease 2019 (COVID-19) vaccine is one of the few vaccines that obtained emergency authorization to combat the fatal pandemic. Despite the fact that some available literature addressed its short-term side effects, there are still limitations on its effects on type 1 diabetes mellitus (T1DM). OBJECTIVES: The aim of the present study was to assess the association between COVID-19 vaccination and diabetic ketoacidosis (DKA) among individuals with T1DM...
October 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38666045/determinants-of-bone-mineral-density-in-iranian-women-with-polycystic-ovary-syndrome
#4
JOURNAL ARTICLE
Fariba Karimi, Parisa Mardani
BACKGROUND: Whether the endocrine aberrations caused by polycystic ovary syndrome (PCOS) might influence bone density in women of reproductive age is controversial. OBJECTIVES: The present study aimed to compare PCOS women to a control group matched in terms of age and body mass index (BMI) regarding bone indices and to clarify the potential relationship between their hormonal changes and bone density. METHODS: This case-control study consisted of 61 PCOS patients, and 35 women with normal ovulatory function served as controls...
October 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38666044/determinants-of-self-monitoring-of-blood-glucose-in-iranian-children-and-adolescents-with-type-1-diabetes
#5
JOURNAL ARTICLE
Farimah Fayyaz, Sepehr Khosravi, Asieh Mosallanejad, Ozra Tabatabaei-Malazy, Seyed Saeed Hashemi Nazari, Maede Shaghaghi
BACKGROUND: Type 1 diabetes mellitus (T1DM) is a prevalent chronic disease among children and adolescents, necessitating effective self-monitoring of blood glucose (SMBG) levels. Understanding the determinants and factors influencing SMBG behavior is crucial for optimizing diabetes management in this population. OBJECTIVES: This study aimed to investigate the frequency of SMBG and identify the determinants influencing factors in children and adolescents with T1DM...
October 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38666043/what-about-my-weight-insufficient-weight-loss-or-weight-regain-after-bariatric-metabolic-surgery
#6
REVIEW
Hamidreza Zefreh, Reza Amani-Beni, Erfan Sheikhbahaei, Farnaz Farsi, Shahrzad Ahmadkaraji, Maryam Barzin, Bahar Darouei, Alireza Khalaj, Shahab Shahabi
CONTEXT: This review study aimed to investigate the definition, etiology, risk factors (RFs), management strategy, and prevention of insufficient weight loss (IWL) and weight regain (WR) following bariatric metabolic surgery (BMS). EVIDENCE ACQUISITION: Electronic databases were searched to retrieve relevant articles. The inclusion criteria were English articles with adult participants assessing the definition, prevalence, etiology, RFs, management strategy, and prevention of IWL/WR...
October 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38666042/type-1-diabetes-and-covid-19-a-literature-review-and-possible-management
#7
REVIEW
Kebria Kashfi, Narges Anbardar, Artin Asadipooya, Kamyar Asadipooya
CONTEXT: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection normally damages the respiratory system but might likewise impair endocrine organs' function. Thyroid dysfunction and hyperglycemia are common endocrine complications of SARS-CoV-2 infection. The onset of type 1 diabetes (T1D) and associated complications, including diabetic ketoacidosis (DKA), hospitalization, and death, are thought to have increased during the coronavirus disease 2019 (COVID-19) pandemic...
October 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38666041/bioinformatic-identification-of-hub-genes-related-to-menopause-obesity-paradox-in-breast-cancer
#8
JOURNAL ARTICLE
Zahra Hosseinpour, Mostafa Rezaei-Tavirani, Mohammad Esmaeil Akbari
BACKGROUND: Breast cancer (BC) is one of the most common cancers in women, significantly contributing to cancer-related death in the modern world. Obesity, as a worldwide epidemic besides the menopausal status, has a paradoxical association with BC. OBJECTIVES: To determine the molecular mechanisms underlying the paradoxical effects of obesity on BC, a comprehensive systems biology analysis was performed. METHODS: Data retrieval, data preprocessing, and differential expression analysis were conducted...
October 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38028251/therapeutic-plasma-exchange-as-a-bridging-therapy-for-the-definitive-treatment-of-a-patient-with-graves-disease-and-methimazole-induced-liver-injury
#9
Dyah Purnamasari, Ardy Wildan, Juferdy Kurniawan, Nadia Ayu Mulansari, Birry Karim, Erwin Danil Yulian
INTRODUCTION: Graves' disease (GD) is an autoimmune condition affecting the thyroid gland. The aim of treating GD is to control the symptoms of hyperthyroidism and achieve long-term remission. Antithyroid drugs (ATDs) are the medications of choice among newly-diagnosed GD patients as they are easy to be delivered and cause remission in more than 50% of patients. However, ATDs increase the risk of hepatotoxicity, especially among patients with liver abnormalities. Patients who cannot tolerate ATDs should receive definitive therapy such as radioactive iodine (RAI) or surgery...
July 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38028250/complications-and-treatment-of-early-onset-type-2-diabetes
#10
REVIEW
Fahimeh Soheilipour, Naghmeh Abbasi Kasbi, Mahshid Imankhan, Delaram Eskandari
CONTEXT: Global reports have revealed a dramatic rise in the number of patients diagnosed with type 2 diabetes (T2DM) over the past three decades in all age groups, even in children and adolescents. The physiologic phenomenon of insulin resistance during puberty, as well as genetic and epigenetic factors, are implicated in this phenomenon. It seems that patients with early-onset T2DM experience a more aggressive clinical course; however, limited treatments available for these patients pose a challenge...
July 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38028249/long-term-ovariectomy-reduces-tolerance-of-rats-to-myocardial-ischemia-reperfusion-injury
#11
JOURNAL ARTICLE
Nasibeh Yousefzadeh, Sajad Jeddi
BACKGROUND: The harmful impact of ovariectomy on myocardial ischemia-reperfusion (M/IR) injury has been established in the short term. OBJECTIVES: In this study, we aimed to investigate the long-term effects of ovariectomy on M/IR injury. METHODS: Two methods involving dorsolateral skin incisions were used to induce the ovariectomized (OVX) rat model. The rats were divided into 2 groups: Control and OVX (n = 6). At the end of the study, the hearts were isolated and subjected to global ischemia using the Langendorff apparatus...
July 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38028248/sphingosine-kinase-2-knockout-mice-resist-hfd-induced-obesity-through-increasing-energy-expenditure
#12
JOURNAL ARTICLE
Jiawei Zhao, Menq-Jer Lee
BACKGROUND: It has been reported that sphingosine kinase (SK) 2 plays a role in maintaining metabolism and glucose homeostasis. However, the mechanism remains uncertain. OBJECTIVES: The present research aimed to further investigate the effect of SK2 knockout on high-fat diet (HFD)-induced obesity and metabolic regulation. METHODS: Male SK2-/- and wild-type (WT) control mice were challenged with HFD for 8 weeks. Then, body composition, inguinal white adipose tissue (IWAT) histology, intraperitoneal glucose tolerance tests (IPGTT), and metabolic parameters were examined, and expression levels of uncoupling protein 1 (UCP1), a key molecular marker of thermogenesis, in IWAT were determined...
July 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38028247/comparison-of-diabetic-ketoacidosis-characteristics-during-and-before-the-covid-19-pandemic
#13
JOURNAL ARTICLE
Nastaran Injinari, Hamed Ghoshouni, Akram Mehrabbeik, Nasim Namiranian, Akram Ghadiri-Anari, Reyhaneh Azizi
BACKGROUND: Despite evidence about the relationship between diabetic ketoacidosis (DKA) and infectious diseases, our knowledge of DKA during the coronavirus disease 2019 (COVID-19) pandemic remains unclear. OBJECTIVES: This study aimed to compare the DKA situation among individuals with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) during the COVID-19 pandemic compared to pre-pandemic. METHODS: This retrospective-longitudinal study included individuals with T1DM and T2DM hospitalized with newly diagnosed DKA before (March to August 2018 and 2019) and during (March to August 2020 and 2021) the COVID-19 pandemic...
July 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38028246/posterior-reversible-encephalopathy-syndrome-as-an-adverse-effect-of-lenvatinib-in-a-patient-with-papillary-thyroid-carcinoma-a-case-report
#14
Daisy Carolina Buenaventura, Hernando Vargas-Sierra, Natalia Aristizabal-Henao, Jose Luis Torres-Grajales, Carolina Aguilar-Londono, Johnayro Gutierrez-Restrepo
Posterior reversible encephalopathy syndrome (PRES) is an uncommon transient neuroradiological phenomenon that develops vasogenic cerebral edema and could be caused by some pharmacological agents, such as molecular-specific target agents. Lenvatinib belongs to the tyrosine kinase inhibitors and was approved in 2015 for progressive locally advanced or metastatic thyroid cancer refractory to radioactive iodine (I-131) treatment. Herein, we present the case of a 65-year-old woman who, while receiving treatment with lenvatinib for radioiodine-refractory metastatic papillary thyroid carcinoma, developed PRES without hypertension at the initial evaluation...
July 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/37662645/neck-ganglioneuroma-mimicking-a-thyroid-nodule-in-a-four-year-old-child-a-case-report-and-review-of-the-literature
#15
Stefania Corrado, Cesare Morgante, Sauro Tassi, Francesco Maccarrone, Gianluca Di Massa, Alfredo Pontecorvi, Giampaolo Papi
INTRODUCTION: Ganglioneuromas are tumors of neurogenic origin usually located in the abdomen, the adrenal glands, and the mediastinum but infrequently found in the neck region. CASE PRESENTATION: We describe the case of a four-year-old Albanian girl presenting with an anterior neck mass initially suspected to be a thyroid nodule. From a clinical point of view, there was no evidence of compression on vital cervical structures. Lab tests detected normal serum thyrotropin, calcitonin, and parathormone concentrations...
April 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/37662644/diabetic-ketoacidosis-in-children-before-and-during-covid-19-pandemic-a-cross-sectional-study
#16
JOURNAL ARTICLE
Mahtab Ordooei, Mehran Karimi, Elahe Akbarian, Zahra Rasoulizadeh
BACKGROUND: Coronavirus disease 2019 (COVID-19) has spread quickly. Comorbidities, such as diabetes, have been determined as critical risk factors for COVID-19. OBJECTIVES: This study aimed to determine the frequency and severity of diabetic ketoacidosis (DKA) in children before and during the COVID-19 pandemic. METHODS: This retrospective study examined children aged less than 18 years diagnosed with DKA hospitalized in Yazd Shahid Sadoughi Hospital from February 20, 2020, to November 21, 2021...
April 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/37654527/diabetes-ketoacidosis-and-covid-19-an-insight-into-the-pathophysiology
#17
JOURNAL ARTICLE
Seyed Amirabbas Ahadiat, Zeinab Hosseinian
No abstract text is available yet for this article.
April 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/37654526/metformin-in-covid-19-is-there-a-role-beyond-glycemic-control
#18
REVIEW
Lakshmi Nagendra, Saptarshi Bhattacharya, Sanjay Kalra, Nitin Kapoor
CONTEXT: The coronavirus disease 2019 (COVID-19) pandemic is still a cause of worldwide health concern. Diabetes and its associated comorbidities are risk factors for mortality and morbidity in COVID-19. Selecting the right antidiabetic drug to achieve optimal glycemic control might mitigate some of the negative impacts of diabetes. Metformin continues to be the most widely administered antidiabetic agent. There is evidence of its beneficial outcome in COVID-19 independent of its glucose-lowering effect...
April 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/37654525/self-reported-male-infertility-and-metabolic-disturbance-a-cross-sectional-study
#19
JOURNAL ARTICLE
Mahbanoo Farhadi-Azar, Marzieh Saei Ghare Naz, Mehrdad Ghahremani, Maryam Mousavi, Fereidoun Azizi, Fahimeh Ramezani Tehrani
BACKGROUND: Male infertility is a growing health problem. It is proposed that infertility is associated with some metabolic abnormalities. OBJECTIVES: This study aimed to examine the prevalence of self-reported male infertility and related metabolic disturbances. METHODS: This is a cross-sectional analysis of the Tehran Lipid and Glucose Study (TLGS). A total of 1526 males participated in the study. Logistic regression was used to examine metabolic factors associated with self-reported male infertility...
April 2023: International Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/37654524/effect-of-a-reduced-calorie-diet-on-plasma-levels-of-inflammatory-and-metabolic-factors-in-overweight-obese-patients-with-cardiovascular-risk-factors
#20
JOURNAL ARTICLE
Javad Nasrollahzadeh, Nafiseh Khandouzi, Mahsa Maroofi
BACKGROUND: Calorie restriction without malnutrition is likely to improve cardiovascular risk factors. OBJECTIVES: The aim of this study was to investigate calorie restriction on markers of cardiometabolic risk in overweight/obese adults with cardiovascular risk factors. METHODS: In a parallel controlled trial, patients with overweight or obesity and one or more cardiovascular risk factor were randomized to a modest reduced-calorie diet (75% of the total calculated energy requirements) or control (no calorie restriction) groups and followed up for two months...
April 2023: International Journal of Endocrinology and Metabolism
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