C Zenoaga-Barbăroșie, L Berca, T Vassu-Dimov, M Toma, M I Nica, O A Alexiu-Toma, C Ciornei, A Albu, S Nica, C Nistor, R Nica
Type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) are diseases caused by the interaction of genetic and non-genetic factors. Therefore, the aim of our study was to investigate the association between six common genetic polymorphisms and T2DM and MetS in males. A total of 120 T2DM, 75 MetS, and 120 healthy controls (HC) were included in the study. ACE ID, eNOS 4a/b, ATR1 A1166C, OXTR (A>G), SOD1 +35A/C, CAT -21A/T gene polymorphisms were genotyped by PCR or PCR-RFLP techniques. T2DM was diagnosed at an earlier age compared to MetS (54 vs 55 years old, p=0...
July 2023: Balkan Journal of Medical Genetics: BJMG