Suresh Hanagavadi, Priyanka Indoria, K S Rajashekar, Rajat Hegde, Smita Hegde, Sujayendra Kulkarni, Chanda Varshini Sindhiya, Vardendra Kulkarni, Suyamindra S Kulkarni, Pramod B Gai
BACKGROUND: Hemophilia A (HA) is a congenital bleeding disorder caused by a deficiency of Factor VIII clotting proteins in the blood. It has an X-linked recessive mode of inheritance. In this study, clinical and hematological manifestations were analyzed and correlated with molecular mutations in patients with HA. METHODS: This study included 90 patients with HA. Plasma coagulation test prothrombin time (PT) correction, factor assay for VIII, inhibitor screening, and quantification tests were performed for all patients...
June 8, 2023: Blood Research