journal
https://read.qxmd.com/read/38590708/hsp90b1-regulates-autophagy-via-pi3k-akt-mtor-signaling-mediating-hnsc-biological-behaviors
#1
JOURNAL ARTICLE
Chao Li, Xiaoyu Lin, Jiping Su
BACKGROUND: Autophagy, a crucial cellular mechanism, facilitates the degradation and removal of misfolded proteins and impaired organelles. Recent research has increasingly highlighted the intimate connection between autophagy and heat shock proteins (HSPs) in the context of tumor development. However, the specific role and underlying mechanisms of heat shock protein 90 beta family member 1 (HSP90B1) in modulating autophagy within head and neck squamous cell carcinoma (HNSCC) remain elusive...
2024: PeerJ
https://read.qxmd.com/read/38590707/exogenous-melatonin-improves-germination-rate-in-buckwheat-under-high-temperature-stress-by-regulating-seed-physiological-and-biochemical-characteristics
#2
JOURNAL ARTICLE
Zemiao Tian, Mengyu Zhao, Junzhen Wang, Qian Yang, Yini Ma, Xinlei Yang, Luping Ma, Yongzhi Qi, Jinbo Li, Muriel Quinet, BaoSheng Shi, Yu Meng
The germinations of three common buckwheat ( Fagopyrum esculentum ) varieties and two Tartary buckwheat ( Fagopyrum tataricum ) varieties seeds are known to be affected by high temperature. However, little is known about the physiological mechanism affecting germination and the effect of melatonin (MT) on buckwheat seed germination under high temperature. This work studied the effects of exogenous MT on buckwheat seed germination under high temperature. MT was sprayed. The parameters, including growth, and physiological factors, were examined...
2024: PeerJ
https://read.qxmd.com/read/38590706/the-comparative-plastisphere-microbial-community-profile-at-kung-wiman-beach-unveils-potential-plastic-specific-degrading-microorganisms
#3
JOURNAL ARTICLE
Nutsuda Chaimusik, Natthaphong Sombuttra, Yeampon Nakaramontri, Penjai Sompongchaiyakul, Chawalit Charoenpong, Bungonsiri Intra, Jirayut Euanorasetr
BACKGROUND: Plastic waste is a global environmental issue that impacts the well-being of humans, animals, plants, and microorganisms. Microplastic contamination has been previously reported at Kung Wiman Beach, located in Chanthaburi province along with the Eastern Gulf of Thailand. Our research aimed to study the microbial population of the sand and plastisphere and isolate microorganisms with potential plastic degradation activity. METHODS: Plastic and sand samples were collected from Kung Wiman Beach for microbial isolation on agar plates...
2024: PeerJ
https://read.qxmd.com/read/38590705/self-reported-side-effects-of-covid-19-vaccines-among-health-professions-students-in-india
#4
JOURNAL ARTICLE
Md Anwarul Azim Majumder, Ambadasu Bharatha, Santosh Kumar, Madhuri Chatterjee, Subir Gupta, Heather Harewood, Keerti Singh, Wms Johnson, Archana Rajasundaram, Sudeshna Banerjee Dutta, Sangishetti Vijay Prasad, Sayeeda Rahman, Russell Kabir, Ali Davod Parsa, Uma Gaur, Ahbab Mohammad Fazle Rabbi, Kandamaran Krishnamurthy, Shegufta Mohammad, Vikram Chode, Mainul Haque, Michael H Campbell
Studies focusing on the safety and common side effects of vaccines play a crucial role in enhancing public acceptance of vaccination. Research is scarce regarding the usage of COVID-19 vaccines and the side effects experienced by health professions students in India and other countries. This study aimed to document self-reported side effects associated with COVID-19 vaccination among medical and dental students of six medical and dental colleges and teaching hospitals in four states (Tamil Nadu, Madhya Pradesh, Gujarat, and West Bengal) of India...
2024: PeerJ
https://read.qxmd.com/read/38590704/carnivore-coexistence-without-competition-giant-otters-are-more-nocturnal-around-dens-than-sympatric-neotropical-otters
#5
JOURNAL ARTICLE
Darren Norris, Fernanda Michalski
Nocturnal activity of tropical otters is rarely reported. To date no studies have documented den use by sympatric giant ( Pteronura brasiliensis ) and neotropical otters ( Lontra longicaudis ). We used camera-traps to monitor den use by sympatric otters along an equatorial Amazonian river. Camera-traps provided evidence that giant otters were more nocturnal around dens than sympatric neotropical otters. Nocturnal activity was recorded in 11% of giant otter photos ( n = 14 of 125 photos), but was recorded only once for neotropical otters...
2024: PeerJ
https://read.qxmd.com/read/38590703/heterogeneity-of-the-effect-of-the-covid-19-pandemic-on-the-incidence-of-metabolic-syndrome-onset-at-a-japanese-campus
#6
JOURNAL ARTICLE
Toshiharu Mitsuhashi
BACKGROUND: The coronavirus disease 2019 (COVID-19) outbreak began in China in December 2019, with the World Health Organization declaring a state of emergency in January 2020. Worldwide implementation of lockdown measures to slow the spread of the virus led to reduced physical activity, disrupted eating habits, mental health issues, and sleep disturbances, which increased the risk of lifestyle-related diseases such as metabolic syndrome (MetS). During the COVID-19 pandemic, healthcare workers, especially intensive care workers, experienced longer working hours and burnout, which further increased the risk of lifestyle-related diseases...
2024: PeerJ
https://read.qxmd.com/read/38590702/selective-concentration-of-iron-titanium-and-zirconium-substrate-minerals-within-gregory-s-diverticulum-an-organ-unique-to-derived-sand-dollars-echinoidea-scutelliformes
#7
JOURNAL ARTICLE
Louis G Zachos, Alexander Ziegler
Gregory's diverticulum, a digestive tract structure unique to a derived group of sand dollars (Echinoidea: Scutelliformes), is filled with sand grains obtained from the substrate the animals inhabit. The simple methods of shining a bright light through a specimen or testing response to a magnet can reveal the presence of a mineral-filled diverticulum. Heavy minerals with a specific gravity of >2.9 g/cm3 are selectively concentrated inside the organ, usually at concentrations one order of magnitude, or more, greater than found in the substrate...
2024: PeerJ
https://read.qxmd.com/read/38590701/the-role-of-cxcl10-as-a-biomarker-for-immunological-response-among-patients-with-leprosy-a-systematic-literature-review
#8
JOURNAL ARTICLE
Flora Ramona Sigit Prakoeswa, Nabila Haningtyas, Listiana Masyita Dewi, Ellen Josephine Handoko, Moch Tabriz Azenta, Muhana Fawwazy Ilyas
INTRODUCTION: Involvement of a chemokine known as C-X-C motif chemokine ligand 10 or CXCL10 in the immunopathology of leprosy has emerged as a possible immunological marker for leprosy diagnosis and needed to be investigate further. The purpose of this systematic review is to assess CXCL10's potential utility as a leprosy diagnostic tool and evaluation of therapy. METHODS: This systematic review is based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020...
2024: PeerJ
https://read.qxmd.com/read/38590700/recombinant-hirudin-attenuates-pulmonary-hypertension-and-thrombosis-in-acute-pulmonary-embolism-rat-model
#9
JOURNAL ARTICLE
Xiang Wei, Yanfen Zou, Shunli Dong, Yi Chen, Guoping Li, Bin Wang
BACKGROUND: Acute pulmonary embolism (APE) is classified as a subset of diseases that are characterized by lung obstruction due to various types of emboli. Current clinical APE treatment using anticoagulants is frequently accompanied by high risk of bleeding complications. Recombinant hirudin (R-hirudin) has been found to have antithrombotic properties. However, the specific impact of R-hirudin on APE remains unknown. METHODS: Sprague-Dawley (SD) rats were randomly assigned to five groups, with thrombi injections to establish APE models...
2024: PeerJ
https://read.qxmd.com/read/38584941/preparation-and-characterization-of-vitamin-e-calcium-soy-protein-isolate-nanoparticles-for-soybean-milk-beverage-fortification
#10
JOURNAL ARTICLE
Heba A I M Taha, Neveen F M Agamy, Tarek N Soliman, Nashwa M Younes, Hesham Ali El-Enshasy, Amira M G Darwish
Soybean milk is a rich plant-based source of protein, and phenolic compounds. This study compared the nutritional value of soybean milk, flour, soy protein isolate (SPI) and evaluated the impact of prepared vitamin E/calcium salt/soy protein isolate nanoparticles (ECSPI-NPs) on fortification of developed soybean milk formulations. Results indicated that soybean flour protein content was 40.50 g/100 g, that fulfills 81% of the daily requirement (DV%), the unsaturated fatty acids (USFs), oleic and linoleic content was 21...
2024: PeerJ
https://read.qxmd.com/read/38584940/analysis-of-twelve-genomes-of-the-bacterium-kerstersia-gyiorum-from-brown-throated-sloths-bradypus-variegatus-the-first-from-a-non-human-host
#11
JOURNAL ARTICLE
Dennis Carhuaricra-Huaman, Irys H L Gonzalez, Patricia L Ramos, Aline M da Silva, Joao C Setubal
Kerstersia gyiorum is a Gram-negative bacterium found in various animals, including humans, where it has been associated with various infections. Knowledge of the basic biology of K. gyiorum is essential to understand the evolutionary strategies of niche adaptation and how this organism contributes to infectious diseases; however, genomic data about K. gyiorum is very limited, especially from non-human hosts. In this work, we sequenced 12 K. gyiorum genomes isolated from healthy free-living brown-throated sloths ( Bradypus variegatus ) in the Parque Estadual das Fontes do Ipiranga (São Paulo, Brazil), and compared them with genomes from isolates of human origin, in order to gain insights into genomic diversity, phylogeny, and host specialization of this species...
2024: PeerJ
https://read.qxmd.com/read/38584939/morphometric-and-taxonomic-approach-to-describe-heterospio-variabilis-annelida-longosomatidae-a-new-species-with-three-size-dependent-morphotypes-from-the-gulf-of-california-eastern-pacific
#12
JOURNAL ARTICLE
Pablo Hernández-Alcántara, Vivianne Solis-Weiss
The Longosomatidae, a poorly known polychaete family, includes only 23 recognized species; in this study, based on morphometric and taxonomic analyses, we describe a new species with three morphotypes: Heterospio variabilis from the Gulf of California, Mexico. The specimens examined exhibit large morphological variations but were clearly separated from close species due to a unique combination of morphological characters: chaetiger 9 as the first elongated chaetiger, four to eight branchial pairs; chaetae from chaetiger 10 forming rings in two rows, posterior row with thin and robust capillaries, anterior row with subuluncini, aristate spines, acicular spines and thick acicular spines...
2024: PeerJ
https://read.qxmd.com/read/38584938/investigating-mortality-salience-as-a-potential-causal-influence-and-moderator-of-responses-to-laboratory-pain
#13
JOURNAL ARTICLE
Beibei You, Hongwei Wen, Todd Jackson
BACKGROUND: Because pain can have profound ramifications for quality of life and daily functioning, understanding nuances in the interplay of psychosocial experiences with pain perception is vital for effective pain management. In separate lines of research, pain resilience and mortality salience have emerged as potentially important psychological correlates of reduced pain severity and increased tolerance of pain. However, to date, there has been a paucity of research examining potentially interactive effects of these factors on pain perception...
2024: PeerJ
https://read.qxmd.com/read/38584937/atherosclerosis-gut-microbiome-and-exercise-in-a-meta-omics-perspective-a-literature-review
#14
REVIEW
Haotian Tang, Yanqing Huang, Didi Yuan, Junwen Liu
BACKGROUND: Cardiovascular diseases are the leading cause of death worldwide, significantly impacting public health. Atherosclerotic cardiovascular diseases account for the majority of these deaths, with atherosclerosis marking the initial and most critical phase of their pathophysiological progression. There is a complex relationship between atherosclerosis, the gut microbiome's composition and function, and the potential mediating role of exercise. The adaptability of the gut microbiome and the feasibility of exercise interventions present novel opportunities for therapeutic and preventative approaches...
2024: PeerJ
https://read.qxmd.com/read/38584936/tailoring-transcranial-alternating-current-stimulation-based-on-endogenous-event-related-p3-to-modulate-premature-responses-a-feasibility-study
#15
JOURNAL ARTICLE
Augusto J Mendes, Alberto Lema, Sandra Carvalho, Jorge Leite
BACKGROUND: Transcranial alternating current stimulation (tACS) is a brain stimulation method for modulating ongoing endogenous oscillatory activity at specified frequency during sensory and cognitive processes. Given the overlap between event-related potentials (ERPs) and event-related oscillations (EROs), ERPs can be studied as putative biomarkers of the effects of tACS in the brain during cognitive/sensory task performance. OBJECTIVE: This preliminary study aimed to test the feasibility of individually tailored tACS based on individual P3 (latency and frequency) elicited during a cued premature response task...
2024: PeerJ
https://read.qxmd.com/read/38584935/relationship-between-intended-force-and-actual-force-comparison-between-athletes-and-non-athletes
#16
JOURNAL ARTICLE
Alex Rizzato, Giovanni Cantarella, Elisa Basso, Antonio Paoli, Luca Rotundo, Patrizia Bisiacchi, Giuseppe Marcolin
This cross-sectional study aimed to investigate whether athletes (ATHL) and non-athletes (NON-ATHL) individuals had similar accuracy in matching intended to actual force during ballistic (BAL) and tonic (TON) isometric contractions. In this cross-sectional study, the subjects were divided into ATHL ( n  = 20; 22.4 ± 2.3 yrs; 73.2 ± 15.7 kg; 1.76 ± 0.08 m) and NON-ATHL ( n  = 20; 24.6 ± 2.4 yrs; 68.2 ± 15.0 kg; 1.73 ± 0.1 m) groups...
2024: PeerJ
https://read.qxmd.com/read/38577416/health-and-ecological-risk-of-heavy-metals-in-agricultural-soils-related-to-tungsten-mining-in-southern-jiangxi-province-china
#17
JOURNAL ARTICLE
Jinhu Lai, Yan Ni, Jinying Xu, Daishe Wu
BACKGROUND: Dayu County, a major tungsten producer in China, experiences severe heavy metal pollution. This study evaluated the pollution status, the accumulation characteristics in paddy rice, and the potential ecological risks of heavy metals in agricutural soils near tungsten mining areas of Dayu County. Furthermore, the impacts of soil properties on the accumulation of heavy metals in soil were explored. METHODS: The geo-accumulation index (Igeo ), the contamination factor (CF), and the pollution load index (PLI) were used to evaluate the pollution status of metals (As, Cd, Cu, Cr, Pb, Mo, W, and Zn) in soils...
2024: PeerJ
https://read.qxmd.com/read/38577415/spatial-habitat-suitability-prediction-of-essential-oil-wild-plants-on-indonesia-s-degraded-lands
#18
JOURNAL ARTICLE
Elga Renjana, Elok Rifqi Firdiana, Melisnawati H Angio, Linda Wige Ningrum, Intani Quarta Lailaty, Apriyono Rahadiantoro, Irfan Martiansyah, Rizmoon Zulkarnaen, Ayyu Rahayu, Puguh Dwi Raharjo, Ilham Kurnia Abywijaya, Didi Usmadi, Rosniati Apriani Risna, Wendell P Cropper, Angga Yudaputra
BACKGROUND: Essential oils are natural products of aromatic plants with numerous uses. Essential oils have been traded worldwide and utilized in various industries. Indonesia is the sixth largest essential oil producing country, but land degradation is a risk to the continuing extraction and utilization of natural products. Production of essential oil plants on degraded lands is a potential strategy to mitigate this risk. This study aimed to identify degraded lands in Indonesia that could be suitable habitats for five wild native essential oil producing plants, namely Acronychia pedunculata (L...
2024: PeerJ
https://read.qxmd.com/read/38577414/seasonal-fluctuations-of-litter-and-soil-collembola-and-their-drivers-in-rainforest-and-plantation-systems
#19
JOURNAL ARTICLE
Winda Ika Susanti, Valentyna Krashevska, Rahayu Widyastuti, Christian Stiegler, Dodo Gunawan, Stefan Scheu, Anton M Potapov
Rainforest conversion and expansion of plantations in tropical regions change local microclimate and are associated with biodiversity decline. Tropical soils are a hotspot of animal biodiversity and may sensitively respond to microclimate changes, but these responses remain unexplored. To address this knowledge gap, here we investigated seasonal fluctuations in density and community composition of Collembola, a dominant group of soil invertebrates, in rainforest, and in rubber and oil palm plantations in Jambi province (Sumatra, Indonesia)...
2024: PeerJ
https://read.qxmd.com/read/38563018/higher-body-condition-with-infection-by-haemoproteus-parasites-in-bananaquits-coereba-flaveola
#20
JOURNAL ARTICLE
Nicole A Gutiérrez-Ramos, Miguel A Acevedo
Parasite transmission is a heterogenous process in host-parasite interactions. This heterogeneity is particularly apparent in vector-borne parasite transmission where the vector adds an additional level of complexity. Haemosporidian parasites, a widespread protist, cause a malaria-like disease in birds globally, but we still have much to learn about the consequences of infection to hosts' health. In the Caribbean, where malarial parasites are endemic, studying host-parasites interactions may give us important insights about energetic trade-offs involved in malarial parasites infections in birds...
2024: PeerJ
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