Mengjie Weng, Binbin Fu, Yongjie Zhuo, Jiaqun Lin, Zhenhuan Zou, Yi Chen, Jiong Cui, Guifen Li, Caiming Chen, Yanfang Xu, Dewen Jiang, Jianxin Wan
OBJECTIVE: Whether serum uric acid (SUA) at baseline could been identiûed as a risk factor for progression in IgA nephropathy (IgAN) patients remains unclear, therefore, long- term SUA control levels must be monitored. We aimed to investigate the relevant factors affecting time-averaged SUA (TA-SUA) and to assess the prognostic value of TA-SUA in IgAN. METHODS: This retrospective study included 152 patients with IgAN. The relationships between TA-SUA and clinicopathological features and renal outcomes (defined as the doubling of the baseline serum creatinine level or end-stage renal disease) were analyzed in groups divided by quartiles of TA-SUA levels, the presence of hyperuricemia, and sex...
2024: PeerJ