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Journals Annals of the American Thoraci...

Annals of the American Thoracic Society

https://read.qxmd.com/read/36961515/association-of-lung-function-decline-with-all-cause-and-cancer-cause-mortality-after-world-trade-center-dust-exposure
#1
JOURNAL ARTICLE
David G Goldfarb, Charles B Hall, Jaeun Choi, Rachel Zeig-Owens, Hillel Cohen, Madeline Cannon, David J Prezant, Michael D Weiden
RATIONALE: In numerous cohorts, lung function decline is associated with all-cause and cardiovascular-cause mortality but the association between forced expiratory volume in one second (FEV1) decline and cancer-cause mortality, particularly after occupational/environmental exposure(s), is unclear. Exposure to dust/smoke from the World Trade Center (WTC) disaster caused inflammation and lung injury in Fire Department of the City of New York (FDNY) rescue/recovery workers. In addition, prior research found that over 10% of the cohort experienced greater than twice the age-related decline in FEV1 (≥64 mL/year)...
March 24, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36961514/a-nine-year-investigation-of-healthcare-industry-payments-to-pulmonologists-in-the-united-states
#2
JOURNAL ARTICLE
Anju Murayama, Hinari Kugo, Yoshika Saito, Hiroaki Saito, Tetsuya Tanimoto, Akihiko Ozaki
RATIONALE: The healthcare industry sometimes makes payments to physicians for non-research and research purposes in the United States. OBJECTIVES: We aimed to evaluate the trends in non-research and research industry payments to pulmonologists since the inception of the Open Payments Database in 2013. METHODS: Using the Open Payments Database between August 2013 and December 2021, this population-based observational cohort study examined non-research and research payments made by the healthcare industry to pulmonologists registered in the National Plan and Provider Enumeration System in the United States...
March 24, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36943405/effects-of-lumacaftor-ivacaftor-on-cystic-fibrosis-disease-progression-in-children-2-through-5-years-of-age-homozygous-for-f508del-cftr-a-phase-2-placebo-controlled-clinical-trial
#3
JOURNAL ARTICLE
Mirjam Stahl, Jobst Roehmel, Monika Eichinger, Felix Doellinger, Lutz Naehrlich, Matthias V Kopp, Anna-Maria Dittrich, Christopher Lee, Olaf Sommerburg, Simon Tian, Tu Xu, Pan Wu, Aniket Joshi, Partha Ray, Margaret E Duncan, Mark O Wielpütz, Marcus A Mall
RATIONALE: Lumacaftor/ivacaftor (LUM/IVA) was shown to be safe and well tolerated in children 2 through 5 years of age with cystic fibrosis (CF) homozygous for F508del-CFTR in a phase 3 open-label study. Improvements in sweat chloride concentration, markers of pancreatic function, and lung clearance index2.5 (LCI2.5 ), along with increases in growth parameters, suggested the potential for early disease modification with LUM/IVA treatment. OBJECTIVE: To further assess the effects of LUM/IVA on CF disease progression in children 2 through 5 years of age using chest magnetic resonance imaging (MRI)...
March 21, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36943239/spirometry-for-transgender-and-non-binary-patients
#4
JOURNAL ARTICLE
Kelly A Roth
No abstract text is available yet for this article.
March 21, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36939838/trends-in-return-of-spontaneous-circulation-and-survival-to-hospital-discharge-for-in-intensive-care-unit-cardiac-arrests
#5
JOURNAL ARTICLE
Leigh M Cagino, Ari Moskowitz, Brahmajee K Nallamothu, Jakob McSparron, Theodore J Iwashyna
RATIONALE: Nearly 3 in 5 in-hospital cardiac arrests occur in the ICU, yet large scale data on the outcomes of in-ICU cardiac arrests have not been published for over a decade. OBJECTIVE: We sought to examine outcomes of in-ICU cardiac arrests evaluating both achievement of ROSC and subsequent survival to hospital discharge and how these have changed over time and by type of cardiac arrest. METHODS: This was an observational study using the Get With The Guidelines® (GWTG-R) registry, an American Heart Associated (AHA)-sponsored, prospective multisite registry of in-hospital cardiac arrest in the United States, including adults >=18 years of age with a confirmed initial cardiac arrest occurring in the ICU who underwent resuscitation...
March 20, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36930796/controlled-diesel-exhaust-exposure-induces-a-concentration-dependent-increase-in-airway-inflammation
#6
JOURNAL ARTICLE
Juma Orach, Christopher Francis Rider, Agnes Che Yan Yuen, Carley Schwartz, Neeloffer Mookherjee, Christopher Carlsten
RATIONALE: Air Pollution exposure is harmful to human airways and its impacts are best studied using concentration-response relationships. However, most concentration-response research on airway health has investigated chronic exposures, with less known about acute effects, which can be robustly studied using controlled human exposures. OBJECTIVES: To investigate the concentration-relationship between airway health measures and diesel exhaust (DE). METHODS: We conducted a double-blinded crossover study with 17 healthy non-smokers exposed to filtered air (FA) and DE standardized to 20, 50 and 150 µg/m3 of particulate matter <2...
March 17, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36930738/novel-pulmonary-cyst-characteristics-associated-with-the-diffusing-capacity-of-the-lung-in-lymphangioleiomyomatosis-a-cross-sectional-study
#7
JOURNAL ARTICLE
Brianna P Matthew, Alfredo Lebron, Yun-Ching Chen, Wesley H Lohr, Shirley F Rollison, Tatyana A Worthy, Amanda M Jones, Patricia Julien-Williams, Mehdi Pirooznia, Marcus Y Chen, Joel Moss, Han Wen
No abstract text is available yet for this article.
March 17, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36920751/vaping-and-health-service-utilization-a-canadian-health-survey-and-health-administrative-data-study
#8
JOURNAL ARTICLE
Teresa To, Cornelia M Borkhoff, Chung-Wai Chow, Theo J Moraes, Robert Schwartz, Nick Vozoris, Anne Van Dam, Chris Langlois, Kimball Zhang, Emilie Terebessy, Jingqin Zhu
RATIONALE: Emerging research suggests that e-cigarette (EC) use may have detrimental health effects, increasing the burden on healthcare systems. OBJECTIVES: This study aims to determine whether young EC users had increased asthma, asthma attacks, and health services use (HSU). METHODS: This cohort study used the linked Canadian Community Health Survey (CCHS, cycles 2015-16 and 2017-18) and health administrative data (January 2015-March 2018)...
March 15, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36917194/morning-chronotype-is-associated-with-improved-adherence-to-continuous-positive-airway-pressure-among-individuals-with-obstructive-sleep-apnea
#9
JOURNAL ARTICLE
Melissa P Knauert, Olurotimi Adekolu, Zhichao Xu, Annan Deng, Jen-Hwa Chu, Stephen Baldassarri, Clete Kushida, H Klar Yaggi, Andrey Zinchuk
RATIONALE: Poor adherence limits the effectiveness of continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA). A better understanding of CPAP adherence is needed to develop novel strategies to improve it. OBJECTIVE(S): To determine if chronotype (morning, evening or intermediate) of patients with OSA is associated with differences in CPAP adherence. If such an association exists, to determine the mechanisms underlying this association...
March 14, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36912897/statins-restore-endothelial-protection-against-complement-activity-in-obstructive-sleep-apnea-a-randomized-trial
#10
JOURNAL ARTICLE
Riddhi Shah, Neha Patel, Memet Emin, Yeliz Celik, Alondra Jimenez, Su Gao, Jared Garfinkel, Ying Wei, Sanja Jelic
RATIONALE: Increased cardiovascular risk in obstructive sleep apnea (OSA) persists after continuous positive airway pressure (CPAP) and alternative therapies are needed. Impaired endothelial protection against complement is a cholesterol-dependent process that initiates endothelial inflammation in OSA, which increases cardiovascular risk. OBJECTIVES: To investigate directly whether cholesterol lowering improves endothelial protection against complement and its pro-inflammatory effects in OSA...
March 13, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36884219/lung-function-decline-in-cystic-fibrosis-impact-of-data-availability-and-modeling-strategies-on-clinical-interpretations
#11
JOURNAL ARTICLE
Rhonda Szczesniak, Eleni-Rosalina Andrinopoulou, Weiji Su, Pedro M Afonso, Pierre-Régis Burgel, Elizabeth Cromwell, Emrah Gecili, Enas Ghulam, Christopher H Goss, Nicole Mayer-Hamblett, Ruth H Keogh, Theodore G Liou, Bruce Marshall, Wayne J Morgan, Joshua S Ostrenga, David J Pasta, Sanja Stanojevic, Claire Wainwright, Grace C Zhou, Gabriela Fernandez, Aliza K Fink, Michael S Schechter
RATIONALE: Studies estimating rate of lung function decline in cystic fibrosis (CF) have been inconsistent regarding methods used. How the methodology used impacts validity of the results and comparability between studies is unknown. OBJECTIVES: The Cystic Fibrosis Foundation established a workgroup whose tasks were to examine the impact of differing approaches to estimating rate of decline in lung function and to provide analysis guidelines. METHODS: We utilized a natural history cohort of 35,252 individuals with CF aged > 6 years of the Cystic Fibrosis Foundation Patient Registry (CFFPR), 2003-2016...
March 8, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36884216/considerations-in-selecting-venues-for-the-ats-international-conference-balancing-competing-priorities-of-the-society-s-diverse-membership
#12
JOURNAL ARTICLE
Gregory P Downey, M Patricia Rivera, Lynn M Schnapp, Irina Petrache, Jesse Roman, Karen J Collishaw
No abstract text is available yet for this article.
March 8, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36867521/disparities-in-the-diagnosis-and-treatment-of-obstructive-sleep-apnea-in-middle-aged-and-older-adults-in-the-united-states
#13
JOURNAL ARTICLE
Christopher N Kaufmann, Adam P Spira, Emerson M Wickwire, Jennifer S Albrecht, Halima Amjad, Chandra L Jackson, Atul Malhotra
No abstract text is available yet for this article.
March 3, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36867520/safety-of-transbronchial-biopsies-in-patients-with-pulmonary-hypertension-systematic-review-and-meta-analysis
#14
JOURNAL ARTICLE
Muhammad Sajawal Ali, Jaskaran Sethi, Uzair Khan Ghori, Jose De Cardenas, Max T Wayne, Fabien Maldonado
RATIONALE: Transbronchial lung biopsies (TBLB) are commonly performed by pulmonologists. Most providers consider pulmonary hypertension (PH) to be at least a relative contraindication to TBLB. This practice is primarily based on expert opinion as there is very little patient outcomes data backing it. OBJECTIVES: We performed a systematic review and meta-analysis of the previously published studies to determine the safety of TBLB in patients with PH. METHODS: MEDLINE, Embase, Scopus, and Google Scholar databases were searched for pertinent studies...
March 3, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36867519/association-between-early-venous-thromboembolism-prophylaxis-bleeding-risk-and-venous-thromboembolism-among-critically-ill-patients-with-thrombocytopenia
#15
JOURNAL ARTICLE
Brandon Pang, Lauren Kearney, Jennifer Maccarone, Jingzhou Zhang, Christopher Kearney, Ruchika Sangani, Divya A Shankar, Kari R Gillmeyer, Anica C Law, Nicholas A Bosch
No abstract text is available yet for this article.
March 3, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36857650/global-regional-and-national-burden-of-mesothelioma-1990-2019-a-systematic-analysis-of-the-global-burden-of-disease-study-2019
#16
JOURNAL ARTICLE
Jonghoon Han, Seoyeon Park, Dong Keon Yon, Seung Won Lee, Wongi Woo, Elena Dragioti, Ai Koyanagi, Louis Jacob, Karel Kostev, Joaquim Radua, Sungsoo Lee, Jae Il Shin, Lee Smith
RATIONALE: Mesothelioma has become a major health burden since the second world war due to the use of asbestos. Although many countries have imposed a ban on asbestos, there remains significant mortality and morbidity from mesothelioma owing to its long latent period and aggressiveness. Also, the use of asbestos is increasing in low-income countries, potentiating risk of mesothelioma in the upcoming decades. Assessment of global burden of mesothelioma is required to take proper measures against the disease...
March 1, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36857649/short-term-evolution-of-nutritional-status-in-patients-with-idiopathic-pulmonary-fibrosis
#17
JOURNAL ARTICLE
Paola Faverio, Alessia Fumagalli, Sara Conti, Fabiana Madotto, Francesco Bini, Sergio Harari, Michele Mondoni, Tiberio Oggionni, Emanuela Barisione, Paolo Ceruti, Maria Chiara Papetti, Bruno Dino Bodini, Antonella Caminati, Angela Valentino, Stefano Centanni, Paola Lanzi, Matteo Della Zoppa, Silvia Crotti, Marco Grosso, Samir Giuseppe Sukkar, Denise Modina, Marco Andreoli, Roberta Nicali, Giulia Suigo, Sara Busnelli, Giuseppe Paciocco, Sara Lettieri, Lorenzo Giovanni Mantovani, Giancarlo Cesana, Alberto Pesci, Fabrizio Luppi
No abstract text is available yet for this article.
March 1, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36867427/trends-and-rural-urban-differences-in-the-initial-prescription-of-low-value-inhaled-corticosteroids-among-us-veterans-with-copd
#18
JOURNAL ARTICLE
Kevin I Duan, Lucas M Donovan, Laura J Spece, Laura C Feemster, Alexander D Bryant, Robert Plumley, Margaret P Collins, David H Au
RATIONALE: Guidelines recommend inhaled corticosteroids (ICS) for patients with chronic obstructive pulmonary disease (COPD) and select indications, including asthma history, high exacerbation risk, or high serum eosinophils. ICS are commonly prescribed outside of these indications despite evidence of harm. We defined "low-value" ICS prescription as receipt of an ICS without evidence of a guideline-recommended indication. ICS prescription patterns are not well characterized and could inform health system interventions to reduce low-value practices...
February 27, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36827233/decision-preferences-in-shared-decision-making-for-lung-cancer-screening-among-white-and-african-american-individuals
#19
JOURNAL ARTICLE
Constantine Daskalakis, Ayako Shimada, Ronald E Myers, Kathleen Eastburn, Melissa A DiCarlo, Christine S Shusted, Julie A Barta
No abstract text is available yet for this article.
February 24, 2023: Annals of the American Thoracic Society
https://read.qxmd.com/read/36827230/association-between-inspired-oxygen-fraction-and-pneumothorax-after-endobronchial-valve-placement-for-emphysema
#20
JOURNAL ARTICLE
Robert J Lentz, See-Wei Low, Timothy Saettele, Otis B Rickman, Matthew Aboudara, Fabien Maldonado
No abstract text is available yet for this article.
February 24, 2023: Annals of the American Thoracic Society
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