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Annals of the American Thoracic Society

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https://read.qxmd.com/read/30763122/association-between-allosensitization-and-waiting-list-outcomes-among-adult-lung-transplant-candidates-in-the-united-states
#1
Laneshia K Tague, Chad A Witt, Derek E Byers, Roger D Yusen, Patrick R Aguilar, Hrishikesh S Kulkarni, Karen Bennett Bain, Keith A Fester, Varun Puri, Daniel Kreisel, Thalachallour Mohanakumar, Elbert P Trulock, Ramsey R Hachem
RATIONALE: Allosensitization may be a barrier to lung transplantation. Currently, consideration is not given to allosensitization when assigning priority on the lung transplant waiting list. OBJECTIVE: We aimed to examine the association between allosensitization and waitlist outcomes. METHODS: We conducted a retrospective single-center cohort study of adults listed for lung transplantation at our center between 1/1/06 and 12/31/16. We screened candidates for human leukocyte antigen (HLA) antibodies prior to listing and examined the association between allosensitization and waitlist outcomes, including likelihood of transplantation and death on the waiting list, using a competing risk model...
February 14, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30763114/poor-metered-dose-inhaler-mdi-technique-is-associated-with-overuse-of-inhaled-corticosteroids-in-copd
#2
Matthew F Griffith, Laura C Feemster, Lucas M Donovan, Laura J Spece, Jerry A Krishnan, Peter K Lindenauer, Mary A McBurnie, Richard A Mularski, David H Au
No abstract text is available yet for this article.
February 14, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30753092/the-annals-of-the-american-thoracic-society-editorial-fellowship-program
#3
Allan J Walkey, Robert Kotloff, David J Lederer
No abstract text is available yet for this article.
February 12, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30742540/toward-enhancing-the-rigor-of-causal-inference-studies
#4
Igor Karp
No abstract text is available yet for this article.
February 11, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30742491/summary-for-clinicians-the-role-of-weight-management-in-the-treatment-of-adult-obstructive-sleep-apnea
#5
Martha E Billings, Vidya Krishnan, George Su, Lucas M Donovan, Sanjay R Patel, David W Hudgel, Amy M Ahasic, Kevin C Wilson, Carey C Thomson
No abstract text is available yet for this article.
February 11, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30742490/volume-capnography-in-the-intensive-care-unit-potential-clinical-applications
#6
John W Kreit
Volume capnography provides a non-invasive, continuous display of the fractional concentration or partial pressure of carbon dioxide versus exhaled volume. Derived measurements and calculations are influenced by changes in both ventilation and perfusion and are therefore useful for assessing both respiratory and cardiovascular function. This article provides an evidence-based review of several potential uses of volume capnography in the ICU: 1) monitoring the effectiveness of ventilation by using end-tidal PCO2 as a surrogate for arterial PCO2; 2) assessing volume-responsiveness; 3) measuring cardiac output; 4) determining prognosis in patients with the acute respiratory distress syndrome; 5) optimizing alveolar recruitment; and 6) excluding pulmonary embolism...
February 11, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30742489/more-on-causal-inference-studies
#7
David J Lederer, Scott C Bell, Alan R Smyth, James D Chalmers
No abstract text is available yet for this article.
February 11, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30714833/patient-preference-to-accept-medical-treatment-is-associated-with-spokesperson-agreement
#8
Andrew J Foy, Benjamin H Levi, Lauren J Van Scoy, Ashley Bucher, Anne Dimmock, Michael J Green
No abstract text is available yet for this article.
February 4, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30714821/cigarette-smoke-exposure-and-radiographic-pulmonary-vascular-morphology-in-the-framingham-heart-study
#9
Andrew J Synn, Chunyi Zhang, George R Washko, Raúl San José Estépar, George T O'Connor, Wenyuan Li, Murray A Mittleman, Mary B Rice
RATIONALE: Cigarette smoke exposure is a risk factor for many lung diseases, and histologic studies suggest tobacco-related vasoconstriction and vessel loss plays a role in the development of emphysema. However, it remains unclear how tobacco affects the pulmonary vasculature in general populations with a typical range of tobacco exposure, and whether these changes are detectable by radiographic methods. OBJECTIVE: To determine whether tobacco exposure in a generally healthy population manifests as lower pulmonary blood vessel volumes and vascular pruning on imaging...
February 4, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30712361/reply-ethics-of-health-research-supported-by-for-profit-cannabis-companies-what-have-we-learned-from-big-tobacco
#10
David J Lederer
No abstract text is available yet for this article.
February 2, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30712358/ethics-of-health-research-supported-by-for-profit-cannabis-companies-what-have-we-learned-from-big-tobacco
#11
Ellen L Burnham, Michelle N Eakin, Smita Pakhale
No abstract text is available yet for this article.
February 2, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30712357/reply-ethics-of-health-research-supported-by-for-profit-cannabis-companies-what-have-we-learned-from-big-tobacco
#12
Sara J Abdallah, Benjamin M Smith, Jean Bourbeau, Dennis Jensen
No abstract text is available yet for this article.
February 2, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30698989/predictors-of-reduced-survival-for-adult-diagnosed-cystic-fibrosis-older-age-at-diagnosis-a-substitute-for-older-age
#13
Steffen Fieuws, Elpis Hatziagorou, Kris De Boeck
No abstract text is available yet for this article.
January 30, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30698985/reply-predictors-of-reduced-survival-for-adult-diagnosed-cystic-fibrosis-older-age-at-diagnosis-a-substitute-for-older-age
#14
Sameer Desai, Hubert Wong, Jenna Sykes, Anne L Stephenson, Joel Singer, Bradley S Quon
No abstract text is available yet for this article.
January 30, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30695649/interstitial-pneumonia-with-autoimmune-features
#15
Bridget A Graney, Aryeh Fischer
"Interstitial pneumonia with autoimmune features" (IPAF) is a research classification proposed by the European Respiratory Society/American Thoracic Society Task Force on Undifferentiated Forms of Connective Tissue Disease-associated Interstitial Lung Disease as an initial step to uniformly define, identify and study patients with interstitial lung disease (ILD) that have features of autoimmunity, yet fall short of a characterizable connective tissue disease. Since its publication in July 2015, there has been substantial interest in IPAF...
January 29, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30695648/the-pathway-to-definitive-palliation-of-malignant-pleural-effusions
#16
Benjamin Shieh, Stéphane Beaudoin, Anne V Gonzalez
No abstract text is available yet for this article.
January 29, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30682323/adult-asthma-among-workers-in-ontario-results-from-the-occupational-disease-surveillance-system
#17
Chloë Logar-Henderson, Jill S MacLeod, Victoria H Arrandale, D Linn Holness, Christopher B McLeod, Alice Peter, Paul A Demers
RATIONALE: Given that approximately 15% of new onset adult asthma cases originate due to exposures in the workplace, there is a need for systematic and ongoing monitoring of risk among workers. OBJECTIVES: To characterize the risk of new onset adult asthma among workers in Ontario. METHODS: We utilized 575,379 provincial accepted time-loss workers' compensation claimants data linked to physician billing data. Workers at-risk of new onset adult asthma were followed from cohort entry date to date of diagnosis, emigration, age 65, death, or end of study period...
January 25, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30678465/fish-oil-supplementation-in-overweight-obese-patients-with-uncontrolled-asthma-a-randomized-trial
#18
Jason E Lang, Edward B Mougey, Md Jobayer Hossain, Floyd Livingston, P Babu Balagopal, Scott Langdon, John J Lima
RATIONALE: Omega-3 fatty acid (n3PUFA) supplementation has been proposed as a promising anti-asthma strategy. The rs59439148 ALOX5 polymorphism affects leukotriene production and possibly inflammatory responses to n3PUFA. OBJECTIVE: Assess the effects of n3PUFA supplementation and ALOX5 genotype on asthma control in patients with obesity and uncontrolled asthma. METHODS: This multi-center trial among 12-25 year olds with overweight/obesity and uncontrolled asthma randomized subjects in a 3:1 allotment to n3PUFA (4g/day) or soy oil control for 24 weeks...
January 25, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30673510/the-prevalence-of-obstructive-lung-disease-in-a-lung-cancer-screening-cohort-analysis-of-the-nlst-acrin-cohort
#19
Juan P de-Torres, Juan P Wisnivesky, Gorka Bastarrika, David O Wilson, Bartolome R Celli, Javier J Zulueta
No abstract text is available yet for this article.
January 23, 2019: Annals of the American Thoracic Society
https://read.qxmd.com/read/30658043/developing-inhaled-antibiotics-in-cystic-fibrosis-current-challenges-and-opportunities
#20
Dave P Nichols, Anthony G Durmowicz, Ann Field, Patrick A Flume, Donald R VanDevanter, Nicole Mayer-Hamblett
No abstract text is available yet for this article.
January 18, 2019: Annals of the American Thoracic Society
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