journal
https://read.qxmd.com/read/38903148/comparative-determination-of-glomerular-filtration-rate-estimation-formulae-in-type-2-diabetic-patients-an-observational-study
#1
COMPARATIVE STUDY
Emmanuel Kwaku Ofori, Irene Nketiah-Dwomo, Emmanuel Aryee Tagoe, Seth Kwabena Amponsah, Ismaila Adams, Eric Nana Yaw Nyarko, Seth Dortey Amanquah
Assessing glomerular filtration rate (GFR) involves collecting timed urine samples for 24 hours, requiring significant time and resources in the clinical setting. Using predictive GFR formulae to assess renal function may be a better alternative. Our goal was to determine which predictive GFR formula had the highest level of concordance with the GFR that has been measured in a resource-poor setting. This is an observational study. We selected fifty (50) individuals diagnosed with type 2 diabetes (T2DM) in Kumasi, Ghana...
2024: BioMed Research International
https://read.qxmd.com/read/38899041/the-role-of-sports-club-participation-on-stability-of-motor-performance-and-body-composition-a-longitudinal-study-in-primary-school-children
#2
JOURNAL ARTICLE
Andreas Speer, Alexandra Ziegeldorf, Heike Streicher, Hagen Wulff, Petra Wagner
METHODS: MP and BC of 295 children (161 girls) with a mean age of 8.42 ± 0.36 years were measured annually with the German Motor Test 6-18. Based on self-reports, children were divided into three groups according to consistent (CON), partial (PAR), and nonparticipation (NO) in SC. NO and PAR were then combined into NO-PAR. The stability of MP and BC was determined using Pearson's correlation coefficient ( r ). Associations of SC participation, MP, and BC were examined using robust mixed-model ANOVA (mmANOVA) additionally with first grade as covariate (ANCOVA)...
2024: BioMed Research International
https://read.qxmd.com/read/38899040/timely-albumin-infusion-may-improve-resource-utilization-in-patients-with-cirrhosis-and-spontaneous-bacterial-peritonitis
#3
JOURNAL ARTICLE
W Ray Kim, Karthik Raghunathan, Greg S Martin, E Anne Davis, Navreet Sandhu Sindhwani, Santosh Telang, Kunal Lodaya
Spontaneous bacterial peritonitis is a life-threatening complication of cirrhosis that can increase healthcare utilization. The impact of albumin administration timing on hospital resource utilization and its optimal timing is unclear, despite its efficacy in improving survival for cirrhosis patients with spontaneous bacterial peritonitis. A retrospective study was conducted to evaluate the influence of the timing of albumin administration on the length of stay and total hospital cost for patients with cirrhosis and spontaneous bacterial peritonitis who require fluid resuscitation...
2024: BioMed Research International
https://read.qxmd.com/read/38899039/antimicrobial-anti-inflammatory-and-wound-healing-properties-of-myrtus-communis-leaf-methanolic-extract-ointment-on-burn-wound-infection-induced-by-methicillin-resistant-staphylococcus-aureus-in-rats
#4
JOURNAL ARTICLE
Zohre Jafari, Hassan Bardania, Mehrzad Jafari Barmak, Saba Eslami, Yaser Mahmoudi-Mourderaz, Narges Roustaei, Mohammad Sharif Talebianpoor, Esmaeel Panahi Kokhdan, Seyed Sajjad Khoramrooz
MATERIALS AND METHODS: In a research experiment, 48 male Wistar rats were anesthetized and second-degree burns were induced on their backs. The rats' wounds were then uniformly inoculated with MRSA. Various treatments were applied to the burn wounds daily, including Myrtus ointment, silver nanoparticles, silver nanoparticles-Myrtus ointment, silver sulfadiazine-Myrtus ointment, silver sulfadiazine 1%, mupirocin ointment, and a positive control. The study measured the antimicrobial effects, wound area, percentage of wound healing, antioxidant capacities, malondialdehyde, and nitric oxide concentrations in the serum of the rats...
2024: BioMed Research International
https://read.qxmd.com/read/38884020/potential-metabolic-pathways-involved-in-osteoporosis-and-evaluation-of-fracture-risk-in-individuals-with-diabetes
#5
REVIEW
Tong Liu, Yanjun Wang, Bing Qian, Pan Li
Diabetes has a significant global prevalence. Chronic hyperglycemia affects multiple organs and tissues, including bones. A large number of diabetic patients develop osteoporosis; however, the precise relationship between diabetes and osteoporosis remains incompletely elucidated. The activation of the AGE-RAGE signaling pathway hinders the differentiation of osteoblasts and weakens the process of bone formation due to the presence of advanced glycation end products. High glucose environment can induce ferroptosis of osteoblasts and then develop osteoporosis...
2024: BioMed Research International
https://read.qxmd.com/read/38884019/long-term-administration-of-omeprazole-induced-hypergastrinemia-and-changed-glucose-homeostasis-and-expression-of-metabolism-related-genes
#6
JOURNAL ARTICLE
Alina Kabaliei, Vitalina Palchyk, Olga Izmailova, Viktoriya Shynkevych, Oksana Shlykova, Igor Kaidashev
INTRODUCTION: PPIs, or proton pump inhibitors, are the most widely prescribed drugs. There is a debate regarding the relationship between long-term PPI use and the risk of type 2 diabetes mellitus (T2DM). A potential connection between T2DM and PPIs could be an elevated gastrin concentration. This study is aimed at investigating the long-term effects of PPI omeprazole (OZ) on glucose homeostasis and pancreatic gene expression profile in mice. METHODS: Healthy adult male BALB/c mice were randomly divided into three equal groups ( n = 10 in each one): (1) experimental mice that received OZ 20 mg/kg; (2) control mice that received 30  μ l saline per os; (3) intact mice without any interventions...
2024: BioMed Research International
https://read.qxmd.com/read/38884018/a-novel-multimodal-biometric-person-authentication-system-based-on-ecg-and-iris-data
#7
JOURNAL ARTICLE
K Ashwini, G N Keshava Murthy, S Raviraja, G A Srinidhi
Existing security issues like keys, pins, and passwords employed presently in almost all the fields that have certain limitations like passwords and pins can be easily forgotten; keys can be lost. To overcome such security issues, new biometric features have shown outstanding improvements in authentication systems as a result of significant developments in biological digital signal processing. Currently, the multimodal authentications have gained huge attention in biometric systems which can be either behavioural or physiological...
2024: BioMed Research International
https://read.qxmd.com/read/38884017/experimental-bracket-design-performance-on-bonding-and-polymerization-of-orthodontic-composite
#8
JOURNAL ARTICLE
Alexandre Daher Yunes Salgado, Victor Pinheiro Feitosa, Manuela Timbó Farrapo, Tainah Oliveira Rifane, Lara Leal Ribeiro, Andressa Silva de Oliveira, Diego Lomonaco
OBJECTIVE: To evaluate the enamel bonding ability and orthodontic adhesive resin degree of conversion using the experimental bracket design. Material and Methods . Thirteen bovine teeth were used in the study. The experimental bracket was modified with a translucent region in the center of its body. After enamel etching, Orthocem orthodontic adhesive (FGM, Joinville, Brazil) was applied on the bracket base for bonding. The groups were divided as follows ( n = 10 per group): (1) control (CB) with standard brackets and (2) spot bracket (SB) with experimental brackets featuring a 0...
2024: BioMed Research International
https://read.qxmd.com/read/38884016/a-bibliometric-analysis-of-telephone-triage-research-to-2021-using-vosviewer
#9
REVIEW
Jill Poots, Jim Morgan, Matteo Curcuruto
Telephone triage services are becoming increasingly commonplace in modern healthcare. Despite this widespread adoption, health researchers and practitioners seeking to understand evidence-based best practice face several challenges. Firstly, the few systematic reviews available yield small sample sizes, suggesting a small amount of research. Secondly, the rapid pace of development of telephone triage technologies means that there may be temporal validity issues with the available research, given some of this research is relatively old...
2024: BioMed Research International
https://read.qxmd.com/read/38807916/effect-of-dnmt3a-r882h-hot-spot-mutations-on-ddx43-promoter-methylation-in-acute-myeloid-leukemia
#10
JOURNAL ARTICLE
Tahere Tabatabaei, Mohammad Reza Rezvany, Bahare Ghasemi, Farzane Vafaei, Masoumeh Kiani Zadeh, Farhad Zaker, Arash Salmaninejad
Epigenetic alterations have been observed in many hematological malignancies, including acute myeloid leukemia (AML). Many of these alterations result from mutations in DNA methyl transferase (DNMT) enzymes, disabling them to methylate target genes in a proper way. In this case-control study, we investigated the association between R882H mutation in DNMT3A gene and DDX43 gene methylation in patients with AML. 47 AML patients and 6 controls were included in this study. After DNA extraction, amplification refractory mutation system (ARMS)-PCR was used to evaluate R882H mutations in DNMT3A gene...
2024: BioMed Research International
https://read.qxmd.com/read/38803515/loss-of-rab25-cooperates-with-oncogenes-in-the-transformation-of-human-mammary-epithelial-cells-hmecs-to-give-rise-to-claudin-low-tumors
#11
JOURNAL ARTICLE
Pooja Joshi, Vijayalakshmi Ayyagari, Samikshya Kandel, Vishnu Modur, Muhammad F Iqbal, Kathy Robinson, John Gao, Krishna Rao
The loss of RAB25 expression-RAS superfamily of GTPase characteristic of numerous breast cancers-corresponds with H-RAS point mutations, particularly in triple-negative breast cancers (TNBC), a subtype associated with a poor prognosis. To address the poorly understood factors dictating the progression of TNBC tumors, we examine the cooperative effects that loss of RAB25 expression in human mammary epithelial cell (HMEC) lines with H-RAS mutations confers in tumorigenesis. HMECs were immortalized by transduction with LXSN CDK4 R24C, a mutant form of cyclin-dependent kinase, followed by transduction with hTERT, a catalytic subunit of the telomerase enzyme...
2024: BioMed Research International
https://read.qxmd.com/read/38803514/relationship-between-intraoperative-bile-culture-outcomes-and-subsequent-postoperative-infectious-complications-a-retrospective-cohort-study
#12
JOURNAL ARTICLE
Jaime Alberto Ramírez-Arbeláez, Ricardo Leonel Arroyave-Zuluaga, Luis Manuel Barrera-Lozano, Verónica Hurtado, Daniel González-Arroyave, Carlos M Ardila
The presence of positive bile culture during intraoperative procedures has been associated with elevated morbidity and mortality rates in hepatobiliopancreatic surgeries, contributing to increased healthcare expenditures. However, the precise impact of bactobilia on the development of postoperative complications remains uncertain due to existing disparities in the published literature. In this retrospective cohort study, we assessed 137 patients who underwent major hepatobiliopancreatic surgery to examine the relationship between intraoperative bile culture outcomes and subsequent postoperative infectious complications...
2024: BioMed Research International
https://read.qxmd.com/read/38778831/antibiotic-resistance-profile-of-staphylococcus-aureus-in-cancer-patients-at-laquintinie-hospital-in-douala-littoral-region-cameroon
#13
JOURNAL ARTICLE
Michael Francis Kengne, Armelle T Mbaveng, Victor Kuete
Cancer and chemotherapy predispose the patients to various bacterial infections. This study is aimed at isolating and establishing the distribution of antibiotic-resistant Staphylococcus aureus from fecal samples in subjects with cancer admitted to the Oncology Department at Laquintinie Hospital in Douala, in the Littoral Region of Cameroon. A cross-sectional study was conducted from October 2021 to March 2023. Cancer and noncancer patients were suffering from Staphylococcus aureus infection. The isolation of Staphylococcus aureus was based on culture on the specific medium...
2024: BioMed Research International
https://read.qxmd.com/read/38764534/complete-blood-count-reference-intervals-for-children-aged-less-than-1-to-12-years-in-the-northern-region-of-ghana
#14
JOURNAL ARTICLE
Gabriel Abbam, Kofi Mensah, Samuel Kwasi Appiah, Charles Nkansah, Samira Daud, Cheryl Namusoke Aikins, Akua Nyarko Osei-Afoakwa, Felix Osei-Boakye, Charles Angnataa Derigubah, Sanda Mohammed, Samuel Tandoh, Simon Bannison Bani
Reliable laboratory diagnostic results are key for evaluating and improving children's health. To interpret these results, child-specific reference intervals (RIs), which account for constant biological changes and physiological development with sex and age, are required, as recommended by the Clinical and Laboratory Standards Institute (CLSI). This study presents age- and sex-specific reference intervals for complete blood count (CBC) parameters in children (<1-12 years old) in the Northern Region of Ghana...
2024: BioMed Research International
https://read.qxmd.com/read/38726293/association-between-gestational-weight-gain-and-maternal-and-birth-outcomes-in-northern-ghana
#15
JOURNAL ARTICLE
John Lapah Niyi, Zhihui Li, Fidelis Zumah
BACKGROUND: Although inappropriate gestational weight gain is considered closely related to adverse maternal and birth outcomes globally, little evidence was found in low- and middle-income countries. Study Objectives . This study is aimed at identifying the determinants of gestational weight gain and examine the association between gestational weight gain and maternal and birth outcomes in the Northern Region of Ghana. Study Methods . The study used a facility-based cross-sectional study design involving 611 antenatal and delivery records in Tatale district, Tamale west, and Gushegu municipal hospitals...
2024: BioMed Research International
https://read.qxmd.com/read/38726292/psychophysiological-adaptations-to-exercise-training-in-covid-19-patients-a-systematic-review
#16
REVIEW
Sameer Badri Al-Mhanna, Alexios Batrakoulis, Martin Hofmeister, Clemens Drenowatz, Wan Syaheedah Wan Ghazali, Georgian Badicu, Hafeez Abiola Afolabi, Mehmet Gülü, Yusuf Wada, Monira I Aldhahi, Pantelis T Nikolaidis
INTRODUCTION: Many COVID-19 patients display adverse symptoms, such as reduced physical ability, poor quality of life, and impaired pulmonary function. Therefore, this systematic review is aimed at evaluating the effectiveness of physical exercise on various psychophysiological indicators among COVID-19 patients who may be at any stage of their illness (i.e., critically ill, hospitalized, postdischarge, and recovering). METHODS: A systematic search was conducted in PubMed, Scopus, ScienceDirect, Web of Science, and Google Scholar from 2019 to 2021...
2024: BioMed Research International
https://read.qxmd.com/read/38726291/web-of-science-based-scientometric-assessment-of-the-importance-of-filtered-water-in-dentistry-spatiotemporal-dynamics-emerging-patterns-and-collaboration
#17
JOURNAL ARTICLE
Franco Mauricio, Cesar Mauricio-Vilchez, Diego Galarza-Valencia, Daniel Alvitez-Temoche, Fran Espinoza-Carhuancho, Frank Mayta-Tovalino
OBJECTIVE: The aim of this study was to examine the characteristics of scientific production related to the use of filtered water in the field of dentistry. Material and Methods . A quantitative and descriptive observational study was carried out with a scientometric approach. Data were collected from the Web of Science (WOS) database during the period January 1991 to December 2023. A search strategy incorporating a combination of MeSH terms, including terms and thesauri related to "filtered water" and "dentistry", was used...
2024: BioMed Research International
https://read.qxmd.com/read/38715713/time-to-death-and-its-predictors-among-neonates-hospitalized-with-sepsis-in-eastern-ethiopia
#18
JOURNAL ARTICLE
Usmael Jibro, Assefa Desalew, Galana Mamo Ayana, Abera Kenay Tura
BACKGROUND: Although neonatal sepsis is a major public health problem contributing to 30-50% of neonatal deaths in low- and middle-income countries, data on predictors of time to death are limited in Eastern Ethiopia. This study is aimed at determining predictors of time to death among neonates with sepsis admitted in public hospitals in Eastern Ethiopia. METHODS: An institutional-based retrospective cohort study was conducted among 415 neonates admitted to referral hospitals in Eastern Ethiopia with sepsis from January 1, 2021, to December 31, 2021...
2024: BioMed Research International
https://read.qxmd.com/read/38707766/association-between-interleukin-6-gene-polymorphism-rs1800795-and-rs1800796-and-type-2-diabetes-mellitus-in-a-ghanaian-population-a-case-control-study-in-the-ho-municipality
#19
JOURNAL ARTICLE
Christian Obirikorang, Sylvester Yao Lokpo, William K B A Owiredu, Linda Ahenkorah-Fondjo, James Osei-Yeboah, Kwabena Obeng Duedu, Esther Ngozi Adejumo, Samuel Ametepe, Evans Adu Asamoah, Shadrack Asiedu Coffie, Emmanuel Nattah Mawuli, Priscilla Essandoh, Precious Kwablah Kwadzokpui
BACKGROUND: There is no conclusive evidence on the association between interleukin- (IL-) 6 gene polymorphism and type 2 diabetes mellitus (type 2 DM). Thus, this study is aimed at evaluating the role of rs1800795 and rs1800796 polymorphisms in the pathogenesis of type 2 DM among Ghanaians in the Ho Municipality. MATERIALS AND METHODS: We recruited into this hospital-based case-control study 174 patients with type 2 DM (75 DM alone and 99 with DM+HTN) and 149 healthy individuals between 2018 and 2020...
2024: BioMed Research International
https://read.qxmd.com/read/38682117/assessing-concordance-of-results-a-comparative-study-of-the-manual-and-automated-urinalysis-methods
#20
COMPARATIVE STUDY
Nicholas Kwame Afriyie Gyamfi, George Nkrumah Osei, Ruth C Brenyah, Lawrence Duah Agyemang, Paulina Ampomah, Kwame Osei Darkwah, Emmanuel Toboh, Richard K D Ephraim
INTRODUCTION: An accurate urine analysis is a good indicator of the status of the renal and genitourinary system. However, limited studies have been done on comparing the diagnostic performance of the fully automated analyser and manual urinalysis especially in Ghana. This study evaluated the concordance of results of the fully automated urine analyser (Sysmex UN series) and the manual method urinalysis at the Komfo Anokye Teaching Hospital in Kumasi, Ghana. Methodology . Sixty-seven (67) freshly voided urine samples were analysed by the automated urine analyser Sysmex UN series and by manual examination at Komfo Anokye Teaching Hospital, Ghana...
2024: BioMed Research International
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