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Journals Journal of Allergy and Clinica...

Journal of Allergy and Clinical Immunology in Practice

https://read.qxmd.com/read/38462070/egg-induced-adult-food-protein-inducedenterocolitis-clinical-phenotypes-natural-history-and-immunological-characteristics
#21
JOURNAL ARTICLE
Purificación Gonzalez-Delgado, Sara Anvari, Jordi Barrachina, Ana L Jimenez Portillo, Teodorikez Jimenez, Francisco M Marco de la Calle, Javier Fernandez
No abstract text is available yet for this article.
March 8, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38530680/impact-of-asthma-medications-during-pregnancy-on-asthma-exacerbation-maternal-and-neonatal-outcomes
#22
JOURNAL ARTICLE
Sangmin Lee, Erin Hetherington, Richard Leigh, Kaylee Ramage, Amy Metcalfe
BACKGROUND: Asthma affects 5% to 13% of pregnant women, and many require daily pharmacotherapy to achieve asthma control; however, adherence to medication during pregnancy often decreases. OBJECTIVE: To understand the association between the use of or adherence to asthma medication with asthma exacerbation and maternal/neonatal outcomes. METHODS: Using linked population-based administrative databases from Alberta, Canada (2012-2018), pregnant women with asthma were categorized based on asthma medication use 1 year before pregnancy: short-acting β-agonists (SABA), inhaled corticosteroids (ICS), and ICS with long-acting β-agonists (ICS+LABA)...
March 7, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38458435/pharmacoequity-biologics-in-the-allergy-clinic-providing-the-right-care-at-the-right-time-every-time-to-everyone
#23
REVIEW
Alexandra E Conway, Jay Lieberman, Christopher D Codispoti, Mahboobeh Mahdavinia, Aikaterini Anagnostou, Karen S Hsu Blatman, David M Lang, John Oppenheimer, Giselle S Mosnaim, Don Bukstein, Marcus Shaker
Pharmacoequity refers to equity in access to pharmacotherapy for all patients and is an especially large barrier to biologic agents in patients with allergic diseases. Value-based care models can prompt clinicians to address social determinants of health, thereby promoting pharmacoequity. Pharmacoequity is influenced by numerous factors including socioeconomic status (SES), which may be mediated through insurance status, educational attainment, and access to specialist care. In addition to lower SES, race and ethnicity, age, locations isolated from care systems, and off-label indications for biologic agents all constitute barriers to pharmacoequity...
March 6, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38458434/upper-respiratory-tract-infections-have-minimal-impact-on-neffy-s-pharmacokinetics-or-pharmacodynamics
#24
JOURNAL ARTICLE
John Oppenheimer, Thomas Casale, Carlos A Camargo, David Fleischer, David Bernstein, Richard Lowenthal, Sarina Tanimoto
No abstract text is available yet for this article.
March 6, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38458433/noveos%C3%A2-and-immunocap%C3%A2-have-similar-performances-for-diagnosing-food-allergies
#25
JOURNAL ARTICLE
Benjamin Trouche-Estival, Joana Vitte, Audrey Martin-Blondel, Marine Michelet, Vianney Gruzelle, Alain Didier, Laurent Guilleminault, Claire Mailhol, Silvia Martinez Rivera, Anaïs De Lima Correia, Camille Taurus, Antoine Blancher, Julien Goret, Caroline Klingebiel, Pol André Apoil
BACKGROUND: The clinical interest of newly available platforms for specific IgE measurement must be evaluated. However, data are lacking for NOVEOS™ (Hycor), in particular for food allergens. OBJECTIVE: We compared technical and clinical performance of two platforms (ImmunoCAP™ and NOVEOS™) for the measurement of specific IgE to 10 food allergens. METHODS: Sera from 289 clinically-characterized patients were tested for IgE specific for six food allergen extracts (egg white, cow's milk, peanut, hazelnut, fish, shrimp) and four molecular allergens (Gal d 1, Bos d 8, Ara h 2, Cor a 14)...
March 6, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38432401/airway-diseases-related-to-the-use-of-cleaning-agents-in-occupational-settings
#26
JOURNAL ARTICLE
Hussein H Mwanga, Orianne Dumas, Nicolas Migueres, Nicole Le Moual, Mohamed F Jeebhay
Exposure to disinfectants and cleaning products (DCP) is now a well-established risk factor for work-related asthma (WRA). However, questions remain on the specific causal agents and pathophysiological mechanisms. Few studies have also reported an association between DCP and rhinitis or chronic obstructive pulmonary disease. This review discusses the recent evidence pertaining to airway diseases attributable to occupational exposure to DCP. In contrast to other agents, the incidence of WRA due to DCP has increased over time...
March 1, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38431251/smaller-differences-in-the-comparative-effectiveness-of-biologics-in-reducing-asthma-related-hospitalizations-compared-to-overall-exacerbations
#27
JOURNAL ARTICLE
Ayobami Akenroye, James Marshall, Andrew L Simon, Christian Hague, Rebecca Costa, Aziza Jamal-Allial, Cheryl N McMahill-Walraven, Katie Haffenreffer, Amy Han, Ann Chen Wu
BACKGROUND: Evidence on the comparative effectiveness of respiratory biologics remains sparse. OBJECTIVE: We sought to evaluate the comparative effectiveness of omalizumab, mepolizumab, benralizumab, and dupilumab in a matched retrospective cohort of patients with asthma. METHODS: We identified patients with asthma aged ≥18 years who were incident users of these biologics between November 1, 2018, and June 30, 2023, in administrative claims data from the FDA's Sentinel System and Merative™ MarketScan® Commercial Database...
February 29, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38428524/high-degree-of-desensitization-after-one-year-of-early-life-peanut-oral-immunotherapy-smacho-randomized-controlled-trial
#28
JOURNAL ARTICLE
Carina Uhl, Susanna Klevebro, Eva Sverremark-Ekström, Sandra G Tedner, Josef Brandström, Chrystalleni Papageorgiou, Erik Melén, Jon R Konradsen, Caroline Nilsson, Anna Asarnoj
BACKGROUND: The prevalence of peanut allergy is about 2% and mostly lifelong. Studies of oral immunotherapy (OIT) with peanut - daily oral intake of an initially low and then increasing dose of peanut - often show problematic side effects but there are indications of better safety and effect in younger children compared with older children and adults. OBJECTIVE: To determine the safety and effectiveness of peanut OIT with a slow up-dosing strategy and low maintenance dose, in peanut allergic children 1-3 years of age, a 1-year interim analysis...
February 28, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423296/clinical-and-histologic-remission-achieved-with-upadacitinib-in-a-patient-with-refractory-eosinophilic-gastritis-and-duodenitis
#29
JOURNAL ARTICLE
Jerry Fu, Twan Sia, Rachel Solecki, Shibani Mallik, Raisa Khuda, Madison Headen, Leeon Bacchus, Michelle Zheng, Tanvi Telukunta, Saad Shami, Stanley Liu, Sripad Sureshbabu, Kathleen Love, Alyssa Roby, Paige McDonald, Yuting Jiang, Dharaneswari Hari Narayanan, Evan Cunningham, Sara Matmatte, Puay Eng Tan, John Leung
There are currently no FDA-approved medications for eosinophilic gastritis and duodenitis. We present a novel case of a patient with eosinophilic gastritis and duodenitis who achieved histologic and symptomatic remission with upadacitinib, a Janus Kinase-1 (JAK1) inhibitor.
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423295/the-prevalence-of-osteoporosis-is-low-in-adult-cutaneous-mastocytosis-patients
#30
JOURNAL ARTICLE
Yannick Degboé, Maella Severino-Freire, Guillaume Couture, Pol-André Apoil, Nicolas Gaudenzio, Olivier Hermine, Adeline Ruyssen-Witrand, Carle Paul, Michel Laroche, Arnaud Constantin, Cristina Bulai Livideanu
BACKGROUND: Systemic mastocytosis (SM) is a clonal disorder of mast cells frequently associated with vertebral osteoporosis (OP) and subsequent vertebral fractures. The natural history of this OP remains unclear. Importantly, we do not know whether OP represents an early event triggered alongside mast cell abnormalities, and whether mast cell clonality is sufficient to trigger osteoporosis. OBJECTIVE: To describe OP in patients with medullar clonality in cutaneous mastocytosis (CM) and monoclonal mast cell activation syndrome (MMAS) and to compare their osteoporosis characteristics to those of non-advanced SM patients (bone marrow mastocytosis (BMM) and indolent systemic mastocytosis (ISM))...
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423294/comparative-impact-of-asthma-biologics-a-nationwide-us-claim-based-analysis
#31
JOURNAL ARTICLE
Taha Al-Shaikhly, Matthew R Norris, Emily H Dennis, Guodong Liu, Timothy J Craig
BACKGROUND: Biologic modifiers targeting type-2 (T2) airway inflammation are effective in reducing asthma exacerbation, however real-world and comparative effectiveness studies remain limited. OBJECTIVE: to examine and compare the real-world impact of anti-T2 asthma biologics METHODS: In this retrospective new user cohort study, we used the MarketScan, a Commercial Claims and Encounters Database, to identify adult patients with asthma who were started on an anti-T2 biologic agent (anti-IL-5s, dupilumab or omalizumab)...
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423293/safety-and-effectiveness-of-bypassing-oral-immunotherapy-buildup-with-an-initial-phase-of-sublingual-immunotherapy-for-higher-risk-food-allergy
#32
JOURNAL ARTICLE
Lianne Soller, Brock A Williams, Raymond Mak, Tiffany Wong, Stephanie C Erdle, Alanna Chomyn, Brittany Tetreault, Kelly Morrison, Lisa Gaudet, Edmond S Chan
BACKGROUND: Due to its favourable safety, sublingual immunotherapy (SLIT) for food allergy has been proposed as an alternative treatment for those in whom oral immunotherapy (OIT) is higher-risk - older children, adolescents, adults, and those with a history of severe reactions. Although safe, SLIT has been shown to be less effective than OIT. OBJECTIVE: To describe the safety of multi-food SLIT in pediatric patients aged 4-18 years of age, and the effectiveness of bypassing OIT buildup with an initial phase of SLIT...
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423292/accuracy-of-spring-pollen-forecasts-in-five-united-states-cities-using-national-allergy-bureau-reporting-as-a-gold-standard
#33
JOURNAL ARTICLE
Divya Shah, Linda Ford, Sergei Ochkur, Susan Kosisky, Stanley Fineman, Frank Virant, Matthew Rank
No abstract text is available yet for this article.
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423291/safety-of-sting-challenge-test-in-patients-with-clonal-mast-cell-diseases
#34
JOURNAL ARTICLE
Arantza Vega-Castro, Gaspar Dalmau-Duch, Lluís Marquès, David González-de-Olano, Berta Ruiz-León
No abstract text is available yet for this article.
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423290/respiratory-diseases-associated-with-organic-dust-exposure
#35
JOURNAL ARTICLE
Jill A Poole, Jose L Zamora-Sifuentes, Leticia De Las Vecillas, Santiago Quirce
Organic dusts are complex bioaerosol mixtures comprised of dust and particulate matter of organic origin. These include components from bacteria, fungi, pollen, and viruses to fragments of animals and plants commonplace to several environmental/occupational settings encompassing agriculture/farming, grain processing, waste/recycling, textile, cotton, woodworking, bird breeding, and more. Organic dust exposures are linked to development of chronic bronchitis, chronic obstructive pulmonary disease (COPD), asthma, asthma-like syndrome, byssinosis, hypersensitivity pneumonitis (HP), and idiopathic pulmonary fibrosis (IPF)...
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423289/consequences-of-nsaid-allergy-on-pain-control-options-for-patients-with-aspirin-exacerbated-respiratory-disease
#36
JOURNAL ARTICLE
Laura B Bailey, Alyson Brown, Rose Corcoran, Jillian C Bensko, Kathleen Buchheit, Tanya M Laidlaw
No abstract text is available yet for this article.
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423288/non-ige-mediated-immediate-drug-induced-hypersensitivity-reactions
#37
JOURNAL ARTICLE
Santiago Alvarez-Arango, Mukesh Kumar, Timothy G Chow, Vito Sabato
Immediate drug-induced hypersensitivity reactions (IDHSRs) have conventionally been attributed to an IgE-mediated mechanism. Nevertheless, it has now been acknowledged that IDHSRs can also occur independently of IgE involvement. Non-IgE-mediated IDHSRs encompass the activation of effector cells, both mast cell (MC) dependent and independent and the initiation of inflammatory pathways through immunogenic and non-immunogenic mechanisms. IDHSRs involve inflammatory mediators beyond histamine, including the platelet-activating factor (PAF), which activates multiple cell types, including smooth muscle, endothelium, and MC, and evidence supports its importance in IgE-mediated reactions in humans...
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423287/effectiveness-of-sirolimus-in-severe-refractory-chronic-spontaneous-urticaria
#38
JOURNAL ARTICLE
Gaytri Patel, David A Khan
No abstract text is available yet for this article.
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423286/characterization-of-alpha-gal-syndrome-and-sensitization-on-eastern-long-island
#39
JOURNAL ARTICLE
Ari Heffes-Doon, Erin McGintee, Meredith Akerman, Erin Banta
No abstract text is available yet for this article.
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38423285/association-between-the-presence-of-food-allergy-and-asthma-outcomes-in-allergic-asthmatic-adults-a-case-control-study
#40
JOURNAL ARTICLE
Diane Pelletier de Chambure, Stéphanie Fry, Cécile Chenivesse
No abstract text is available yet for this article.
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
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